A novel electrode modified with silver nanoparticles was fabricated. It is found that the reducibility of silver nanoparticles is higher than for bulk silver by comparing a silver nanoparticles modified electrode with a silver micro-disk electrode. When SCN-
was added, a new oxidation peak occurred and the anodic peak current of silver nanoparticles decreased. The new anodic peak current is proportional to the thiocyanate concentration in the range of 5.0×10-7
mol/L in pH 6.0 NaH2PO4-Na2HPO4 buffer solutions (PBS). The detection limit (S/N=3) is 4×10-8
mol/L. This method has been applied to the determination of saliva (smoker and non-smoker).