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Open AccessArticle

Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System

School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore
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Author to whom correspondence should be addressed.
Academic Editors: Dragan Indjin, Željka Cvejić and Małgorzata Jędrzejewska-Szczerska
Sensors 2017, 17(2), 357; https://doi.org/10.3390/s17020357
Received: 4 January 2017 / Revised: 27 January 2017 / Accepted: 9 February 2017 / Published: 12 February 2017
Photoacoustic microscopy (PAM) is a scalable bioimaging modality; one can choose low acoustic resolution with deep penetration depth or high optical resolution with shallow imaging depth. High spatial resolution and deep penetration depth is rather difficult to achieve using a single system. Here we report a switchable acoustic resolution and optical resolution photoacoustic microscopy (AR-OR-PAM) system in a single imaging system capable of both high resolution and low resolution on the same sample. Lateral resolution of 4.2 µm (with ~1.4 mm imaging depth) and lateral resolution of 45 μm (with ~7.6 mm imaging depth) was successfully demonstrated using a switchable system. In vivo blood vasculature imaging was also performed for its biological application. View Full-Text
Keywords: photoacoustic imaging; AR-PAM; OR-PAM; microscopy; deep tissue imaging photoacoustic imaging; AR-PAM; OR-PAM; microscopy; deep tissue imaging
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MDPI and ACS Style

Moothanchery, M.; Pramanik, M. Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System. Sensors 2017, 17, 357. https://doi.org/10.3390/s17020357

AMA Style

Moothanchery M, Pramanik M. Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System. Sensors. 2017; 17(2):357. https://doi.org/10.3390/s17020357

Chicago/Turabian Style

Moothanchery, Mohesh; Pramanik, Manojit. 2017. "Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System" Sensors 17, no. 2: 357. https://doi.org/10.3390/s17020357

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