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Short Note

(2,3-Dihydro-1H-indol-5-ylmethyl)amine

by
Vladimir A. Ogurtsov
1 and
Oleg A. Rakitin
1,2,*
1
N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, Russia
2
Nanotechnology Education and Research Center, South Ural State University, 76 Lenina Avenue, 454080 Chelyabinsk, Russia
*
Author to whom correspondence should be addressed.
Molbank 2021, 2021(3), M1248; https://doi.org/10.3390/M1248
Submission received: 15 June 2021 / Revised: 22 June 2021 / Accepted: 24 June 2021 / Published: 5 July 2021
(This article belongs to the Collection Heterocycle Reactions)

Abstract

New (2,3-dihydro-1H-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolution mass-spectrometry, 1H, 13C NMR and IR spectroscopy and mass-spectrometry. The resulting compound is a convenient intermediate for various disubstituted 1-(indolin-5-yl)methanamines, which may be of interest as substances with useful pharmacological properties.
Keywords: 2,3-dihydroindoles (indolines); (2,3-dihydro-1H-indol-5-ylmethyl)amine; deprotection; biological activity 2,3-dihydroindoles (indolines); (2,3-dihydro-1H-indol-5-ylmethyl)amine; deprotection; biological activity
Graphical Abstract

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MDPI and ACS Style

Ogurtsov, V.A.; Rakitin, O.A. (2,3-Dihydro-1H-indol-5-ylmethyl)amine. Molbank 2021, 2021, M1248. https://doi.org/10.3390/M1248

AMA Style

Ogurtsov VA, Rakitin OA. (2,3-Dihydro-1H-indol-5-ylmethyl)amine. Molbank. 2021; 2021(3):M1248. https://doi.org/10.3390/M1248

Chicago/Turabian Style

Ogurtsov, Vladimir A., and Oleg A. Rakitin. 2021. "(2,3-Dihydro-1H-indol-5-ylmethyl)amine" Molbank 2021, no. 3: M1248. https://doi.org/10.3390/M1248

APA Style

Ogurtsov, V. A., & Rakitin, O. A. (2021). (2,3-Dihydro-1H-indol-5-ylmethyl)amine. Molbank, 2021(3), M1248. https://doi.org/10.3390/M1248

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