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4-(3-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)thieno[3,2-d]pyrimidine

Department of Chemistry, Mokwon University, Doanbuk-Ro 88, Daejeon 35349, Korea
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Molbank 2020, 2020(2), M1136; https://doi.org/10.3390/M1136
Received: 3 May 2020 / Revised: 15 May 2020 / Accepted: 17 May 2020 / Published: 17 May 2020
A new hybrid compound, 4-(3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)thieno[3,2-d]pyrimidine 3, with promising biological activity was efficiently synthesized by the reaction of 3-phenyl-1-(thieno[3,2-d]pyrimidin-4-yl)-1H-pyrazol-5-amine with Vilsmeier–Haack reagent and subsequent treatment with ammonium carbonate. The structure of the synthesized compound was fully characterized by 1H-, 13C-NMR, IR spectroscopy, mass-spectrometry and elemental analysis. View Full-Text
Keywords: thieno[3,2-d]pyrimidine; pyrazolo[3,4-d]pyrimidine; Vilsmeier–Haack reagent thieno[3,2-d]pyrimidine; pyrazolo[3,4-d]pyrimidine; Vilsmeier–Haack reagent
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Noh, E.S.; Kim, S.M.; Song, Y.-H. 4-(3-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)thieno[3,2-d]pyrimidine. Molbank 2020, 2020, M1136.

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