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Pathophysiological, Molecular and Therapeutic Issues of Nonalcoholic Fatty Liver Disease: An Overview
Review

Cardio-Metabolic Disorders in Non-Alcoholic Fatty Liver Disease

1
Internal Medicine 3, Department of Medicine DIMED, University of Padova, 35122 Padova, Italy
2
Department of Medicine, Klinikum Rheine, 48431 Rheine, Germany
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(9), 2215; https://doi.org/10.3390/ijms20092215
Received: 23 March 2019 / Revised: 19 April 2019 / Accepted: 28 April 2019 / Published: 6 May 2019
With the progressive epidemics of obesity, non-alcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease in adults and children. The increasing prevalence and incidence of NAFLD with advanced fibrosis is concerning because patients appear to experience higher non-liver-related morbidity and mortality than the general population. Recent clinical evidence suggests that NAFLD is directly associated with an increased risk of cardio-metabolic disorders. This mini review describes briefly the current understanding of the pathogenesis of NAFLD, summarizing the link between NAFLD and cardio-metabolic complications, focusing mainly upon ischemic stroke, type 2 diabetes mellitus (DM), hypertension, chronic kidney disease (CKD) and cardiac arrhythmias. In addition, it describes briefly the current understanding of the pathogenesis of NAFLD. View Full-Text
Keywords: non-alcoholic fatty liver disease; cardio-metabolic disorders; hypertension; diabetes; dyslipidemia; chronic kidney disease; cardiac arrhythmia; ischemic stroke non-alcoholic fatty liver disease; cardio-metabolic disorders; hypertension; diabetes; dyslipidemia; chronic kidney disease; cardiac arrhythmia; ischemic stroke
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MDPI and ACS Style

El Hadi, H.; Di Vincenzo, A.; Vettor, R.; Rossato, M. Cardio-Metabolic Disorders in Non-Alcoholic Fatty Liver Disease. Int. J. Mol. Sci. 2019, 20, 2215. https://doi.org/10.3390/ijms20092215

AMA Style

El Hadi H, Di Vincenzo A, Vettor R, Rossato M. Cardio-Metabolic Disorders in Non-Alcoholic Fatty Liver Disease. International Journal of Molecular Sciences. 2019; 20(9):2215. https://doi.org/10.3390/ijms20092215

Chicago/Turabian Style

El Hadi, Hamza, Angelo Di Vincenzo, Roberto Vettor, and Marco Rossato. 2019. "Cardio-Metabolic Disorders in Non-Alcoholic Fatty Liver Disease" International Journal of Molecular Sciences 20, no. 9: 2215. https://doi.org/10.3390/ijms20092215

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