Next Article in Journal
A Novel Immunochromatographic Strip for Antigen Detection of Avian Infectious Bronchitis Virus
Next Article in Special Issue
Hepatoprotective Effect of Kombucha Tea in Rodent Model of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
Previous Article in Journal
Applicability of Supraclavicular Oxygenated and Total Hemoglobin Evaluated by Near-Infrared Time-Resolved Spectroscopy as Indicators of Brown Adipose Tissue Density in Humans
Previous Article in Special Issue
Pathophysiological, Molecular and Therapeutic Issues of Nonalcoholic Fatty Liver Disease: An Overview
Article Menu
Issue 9 (May-1) cover image

Export Article

Open AccessReview

Cardio-Metabolic Disorders in Non-Alcoholic Fatty Liver Disease

1
Internal Medicine 3, Department of Medicine DIMED, University of Padova, 35122 Padova, Italy
2
Department of Medicine, Klinikum Rheine, 48431 Rheine, Germany
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(9), 2215; https://doi.org/10.3390/ijms20092215
Received: 23 March 2019 / Revised: 19 April 2019 / Accepted: 28 April 2019 / Published: 6 May 2019
  |  
PDF [478 KB, uploaded 6 May 2019]
  |  

Abstract

With the progressive epidemics of obesity, non-alcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease in adults and children. The increasing prevalence and incidence of NAFLD with advanced fibrosis is concerning because patients appear to experience higher non-liver-related morbidity and mortality than the general population. Recent clinical evidence suggests that NAFLD is directly associated with an increased risk of cardio-metabolic disorders. This mini review describes briefly the current understanding of the pathogenesis of NAFLD, summarizing the link between NAFLD and cardio-metabolic complications, focusing mainly upon ischemic stroke, type 2 diabetes mellitus (DM), hypertension, chronic kidney disease (CKD) and cardiac arrhythmias. In addition, it describes briefly the current understanding of the pathogenesis of NAFLD. View Full-Text
Keywords: non-alcoholic fatty liver disease; cardio-metabolic disorders; hypertension; diabetes; dyslipidemia; chronic kidney disease; cardiac arrhythmia; ischemic stroke non-alcoholic fatty liver disease; cardio-metabolic disorders; hypertension; diabetes; dyslipidemia; chronic kidney disease; cardiac arrhythmia; ischemic stroke
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

El Hadi, H.; Di Vincenzo, A.; Vettor, R.; Rossato, M. Cardio-Metabolic Disorders in Non-Alcoholic Fatty Liver Disease. Int. J. Mol. Sci. 2019, 20, 2215.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top