Next Article in Journal
Ovalbumin with Glycated Carboxyl Groups Shows Membrane-Damaging Activity
Next Article in Special Issue
Structural Characterization of Core Region in Erwinia amylovora Lipopolysaccharide
Previous Article in Journal
Tenebrio molitor Larvae Inhibit Adipogenesis through AMPK and MAPKs Signaling in 3T3-L1 Adipocytes and Obesity in High-Fat Diet-Induced Obese Mice
Previous Article in Special Issue
Identification and Characterization of Lipopolysaccharide Induced TNFα Factor from Blunt Snout Bream, Megalobrama amblycephala
Article Menu
Issue 3 (March) cover image

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2017, 18(3), 519;

Comparative Genomics of the Aeromonadaceae Core Oligosaccharide Biosynthetic Regions

Department of Genética, Microbiología y Estadística, Universidad de Barcelona, Diagonal 643, 08071 Barcelona, Spain
Author to whom correspondence should be addressed.
Academic Editor: William Chi-shing Cho
Received: 7 February 2017 / Revised: 23 February 2017 / Accepted: 26 February 2017 / Published: 28 February 2017
(This article belongs to the Special Issue Lipopolysaccharides (LPSs))
Full-Text   |   PDF [1203 KB, uploaded 28 February 2017]   |  


Lipopolysaccharides (LPSs) are an integral part of the Gram-negative outer membrane, playing important organizational and structural roles and taking part in the bacterial infection process. In Aeromonas hydrophila, piscicola, and salmonicida, three different genomic regions taking part in the LPS core oligosaccharide (Core-OS) assembly have been identified, although the characterization of these clusters in most aeromonad species is still lacking. Here, we analyse the conservation of these LPS biosynthesis gene clusters in the all the 170 currently public Aeromonas genomes, including 30 different species, and characterise the structure of a putative common inner Core-OS in the Aeromonadaceae family. We describe three new genomic organizations for the inner Core-OS genomic regions, which were more evolutionary conserved than the outer Core-OS regions, which presented remarkable variability. We report how the degree of conservation of the genes from the inner and outer Core-OS may be indicative of the taxonomic relationship between Aeromonas species. View Full-Text
Keywords: Aeromonas; genomics; inner core oligosaccharide; outer core oligosaccharide; lipopolysaccharide Aeromonas; genomics; inner core oligosaccharide; outer core oligosaccharide; lipopolysaccharide

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material


Share & Cite This Article

MDPI and ACS Style

Forn-Cuní, G.; Merino, S.; Tomás, J.M. Comparative Genomics of the Aeromonadaceae Core Oligosaccharide Biosynthetic Regions. Int. J. Mol. Sci. 2017, 18, 519.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top