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Amino Acid Synthesis in a Supercritical Carbon Dioxide - Water System

International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan
Department of Molecular Cell Biology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, Japan
Sekisui Chemical Co., Ltd., 2-1 Hyakuyama, Shimamoto-cho, Mishima-gun, Osaka, Japan
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2009, 10(6), 2722-2732;
Received: 21 May 2009 / Revised: 5 June 2009 / Accepted: 8 June 2009 / Published: 15 June 2009
(This article belongs to the Special Issue Origin of Life)
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Mars is a CO2-abundant planet, whereas early Earth is thought to be also CO2-abundant. In addition, water was also discovered on Mars in 2008. From the facts and theory, we assumed that soda fountains were present on both planets, and this affected amino acid synthesis. Here, using a supercritical CO2/liquid H2O (10:1) system which mimicked crust soda fountains, we demonstrate production of amino acids from hydroxylamine (nitrogen source) and keto acids (oxylic acid sources). In this research, several amino acids were detected with an amino acid analyzer. Moreover, alanine polymers were detected with LC-MS. Our research lights up a new pathway in the study of life’s origin. View Full-Text
Keywords: supercritical carbon oxide; amino acid; prebiotic chemistry; soda fountain; Mars supercritical carbon oxide; amino acid; prebiotic chemistry; soda fountain; Mars

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Fujioka, K.; Futamura, Y.; Shiohara, T.; Hoshino, A.; Kanaya, F.; Manome, Y.; Yamamoto, K. Amino Acid Synthesis in a Supercritical Carbon Dioxide - Water System. Int. J. Mol. Sci. 2009, 10, 2722-2732.

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