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Review

Artemisia abrotanum L. (Southern Wormwood)—History, Current Knowledge on the Chemistry, Biological Activity, Traditional Use and Possible New Pharmaceutical and Cosmetological Applications

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Chair and Department of Pharmaceutical Botany, Medical College, Jagiellonian University, ul. Medyczna 9, 30-688 Kraków, Poland
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Family Medicine Clinic, Medizinisches Versorgungszentrum (MVZ) Burgbernheim GmbH, Gruene Baumgasse 2, 91593 Burgbernheim, Germany
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Museum of Pharmacy, Medical College, Jagiellonian University, ul. Floriańska 25, 31-019 Kraków, Poland
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Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Białystok, ul. Mickiewicza 2a, 15-230 Białystok, Poland
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Authors to whom correspondence should be addressed.
Academic Editor: William Setzer
Molecules 2021, 26(9), 2503; https://doi.org/10.3390/molecules26092503
Received: 8 March 2021 / Revised: 13 April 2021 / Accepted: 14 April 2021 / Published: 25 April 2021
(This article belongs to the Special Issue Phytotherapy: Medicinal Plants and Natural Products in Healthcare)
Artemisia abrotanum L. (southern wormwood) is a plant species with an important position in the history of European and Asian medicine. It is a species famous as a medicinal plant in Central Asia, Asia Minor, and in South-East and Central Europe. The raw materials obtained from this species are Abrotani herba and Abrotani folium. In the traditional European medicine, they have been used successfully most of all in liver and biliary tract diseases, in parasitic diseases in children and as antipyretic medication. In the official European medicine, this plant species is recommended by the French Pharmacopoeia for use in homeopathy. In many European countries, it is used traditionally in allopathy. The latest studies on the biological activity of extracts from the aboveground parts of the plant and/or the leaves, and/or the essential oil have provided evidence of other possible applications related to their antibacterial, antifungal, antioxidant, anticancer, and antiallergic properties. The latest studies have also focused on the repellent activity of the essential oil of this species and the possibility to use it in the prevention of diseases in which insects are the vectors. The main substances obtained from the plant that are responsible for this activity are: the essential oil, coumarins, phenolic acids, and flavonoids. Some of the latest investigations emphasize the large differences in the composition of the essential oil, determined by the geographical (climatic) origin of the plant. A. abrotanum is recommended by the European Cosmetic Ingredients Database (CosIng) as a source of valuable cosmetic ingredients. Additionally, the leaves of this species possess a well-established position in the food industry. This plant species is also the object of biotechnological studies. View Full-Text
Keywords: Artemisia abrotanum; southern wormwood; traditional medicinal use; chemical composition; biological activity; potential medicinal value; position in cosmetology; biotechnological studies Artemisia abrotanum; southern wormwood; traditional medicinal use; chemical composition; biological activity; potential medicinal value; position in cosmetology; biotechnological studies
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MDPI and ACS Style

Ekiert, H.; Knut, E.; Świątkowska, J.; Klin, P.; Rzepiela, A.; Tomczyk, M.; Szopa, A. Artemisia abrotanum L. (Southern Wormwood)—History, Current Knowledge on the Chemistry, Biological Activity, Traditional Use and Possible New Pharmaceutical and Cosmetological Applications. Molecules 2021, 26, 2503. https://doi.org/10.3390/molecules26092503

AMA Style

Ekiert H, Knut E, Świątkowska J, Klin P, Rzepiela A, Tomczyk M, Szopa A. Artemisia abrotanum L. (Southern Wormwood)—History, Current Knowledge on the Chemistry, Biological Activity, Traditional Use and Possible New Pharmaceutical and Cosmetological Applications. Molecules. 2021; 26(9):2503. https://doi.org/10.3390/molecules26092503

Chicago/Turabian Style

Ekiert, Halina, Ewa Knut, Joanna Świątkowska, Paweł Klin, Agnieszka Rzepiela, Michał Tomczyk, and Agnieszka Szopa. 2021. "Artemisia abrotanum L. (Southern Wormwood)—History, Current Knowledge on the Chemistry, Biological Activity, Traditional Use and Possible New Pharmaceutical and Cosmetological Applications" Molecules 26, no. 9: 2503. https://doi.org/10.3390/molecules26092503

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