Optical Resolution of Rimantadine
AbstractThis work discloses a new procedure for the resolution of commercially available racemic rimantadine hydrochloride to enantiomerically pure (S)-rimantadine using (R)-phenoxypropionic acid as a recyclable resolving reagent. Good chemical yields, operational ease, and low-cost structure underscore the preparative value of this method for the production of enantiomerically pure rimantadine for medicinal or synthetic studies. View Full-Text
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Han, J.; Takeda, R.; Sato, T.; Moriwaki, H.; Abe, H.; Izawa, K.; Soloshonok, V.A. Optical Resolution of Rimantadine. Molecules 2019, 24, 1828.
Han J, Takeda R, Sato T, Moriwaki H, Abe H, Izawa K, Soloshonok VA. Optical Resolution of Rimantadine. Molecules. 2019; 24(9):1828.Chicago/Turabian Style
Han, Jianlin; Takeda, Ryosuke; Sato, Tatsunori; Moriwaki, Hiroki; Abe, Hidenori; Izawa, Kunisuke; Soloshonok, Vadim A. 2019. "Optical Resolution of Rimantadine." Molecules 24, no. 9: 1828.
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