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Open AccessFeature PaperReview

Chiral Derivatives of Xanthones with Antimicrobial Activity

1
Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
2
Interdisciplinary Center of Marine and Environmental Research (CIIMAR), University of Porto, Edificio do Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4050-208 Matosinhos, Portugal
3
Institute of Research and Advanced Training in Health Sciences and Technologies, Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra, 1317, 4585-116 Gandra PRD, Portugal
*
Author to whom correspondence should be addressed.
Molecules 2019, 24(2), 314; https://doi.org/10.3390/molecules24020314
Received: 30 December 2018 / Revised: 12 January 2019 / Accepted: 14 January 2019 / Published: 16 January 2019
According to the World Health Organization, the exacerbated use of antibiotics worldwide is increasing multi-resistant infections, especially in the last decade. Xanthones are a class of compounds receiving great interest in drug discovery and development that can be found as natural products or obtained by synthesis. Many derivatives of xanthones are chiral and associated with relevant biological activities, including antimicrobial. The aim of this review is to compile information about chiral derivatives of xanthones from natural sources and their synthesized examples with antimicrobial activity. View Full-Text
Keywords: antimicrobial; xanthones; chirality; chiral derivatives of xanthones; caged xanthones antimicrobial; xanthones; chirality; chiral derivatives of xanthones; caged xanthones
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MDPI and ACS Style

Araújo, J.; Fernandes, C.; Pinto, M.; Tiritan, M.E. Chiral Derivatives of Xanthones with Antimicrobial Activity. Molecules 2019, 24, 314.

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