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Open AccessArticle

Graphene-Derivatized Silica Composite as Solid-Phase Extraction Sorbent Combined with GC–MS/MS for the Determination of Polycyclic Musks in Aqueous Samples

by 1,2, 1,2, 1,2, 1, 1 and 1,2,*
1
Beijing Research Center for Agricultural Standards and Testing, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China
2
Beijing Municipal Key Laboratory of Agriculture Environment Monitoring, Beijing 100097, China
*
Author to whom correspondence should be addressed.
Molecules 2018, 23(2), 318; https://doi.org/10.3390/molecules23020318
Received: 6 January 2018 / Revised: 25 January 2018 / Accepted: 1 February 2018 / Published: 2 February 2018
(This article belongs to the Special Issue Solid Phase Extraction: State of the Art and Future Perspectives)
Polycyclic musks (PCMs) have recently received growing attention as emerging contaminants because of their bioaccumulation and potential ecotoxicological effects. Herein, an effective method for the determination of five PCMs in aqueous samples is presented. Reduced graphene oxide-derivatized silica ([email protected]) particles were prepared from graphene oxide and aminosilica microparticles and characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy. PCMs were preconcentrated using [email protected] as the solid-phase extraction sorbent and quantified by gas chromatography–tandem mass spectrometry. Several experimental parameters, such as eluent, elution volume, sorbent amount, pH, and sample volume were optimized. The correlation coefficient (R) ranged from 0.9958 to 0.9992, while the limits of detection and quantitation for the five PCMs were 0.3–0.8 ng/L and 1.1–2.1 ng/L, respectively. Satisfactory recoveries were obtained for tap water (86.6–105.9%) and river water samples (82.9–107.1%), with relative standard deviations <10% under optimal conditions. The developed method was applied to analyze PCMs in tap and river water samples from Beijing, China. Galaxolide (HHCB) and tonalide (AHTN) were the main PCM components detected in one river water sample at concentrations of 18.7 for HHCB, and 11.7 ng/L for AHTN. View Full-Text
Keywords: graphene; solid-phase extraction; polycyclic musks; water; GC–MS/MS graphene; solid-phase extraction; polycyclic musks; water; GC–MS/MS
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MDPI and ACS Style

Li, C.; Chen, J.; Chen, Y.; Wang, J.; Ping, H.; Lu, A. Graphene-Derivatized Silica Composite as Solid-Phase Extraction Sorbent Combined with GC–MS/MS for the Determination of Polycyclic Musks in Aqueous Samples. Molecules 2018, 23, 318.

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