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Molecules 2018, 23(11), 2851;

Synthetic Methodologies to Gold Nanoshells: An Overview

Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, QC H3A 0B8, Canada
Research Center, Montreal Heart Institute, 5000 Belanger Street, Montreal, QC H1T 1C8, Canada
Department of Electrical Engineering Ecole Polytechnique de Montreal, C.P. 6079 succ. Centre-ville, Montreal, QC H3C 3A7, Canada
Authors to whom correspondence should be addressed.
Received: 15 October 2018 / Revised: 27 October 2018 / Accepted: 29 October 2018 / Published: 2 November 2018
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Gold nanostructures that can be synthetically articulated to adapt diverse morphologies, offer a versatile platform and tunable properties for applications in a variety of areas, including biomedicine and diagnostics. Among several conformational architectures, gold nanoshells provide a highly advantageous combination of properties that can be fine-tuned in designing single or multi-purpose nanomaterials, especially for applications in biology. One of the important parameters for evaluating the efficacy of gold nano-architectures is their reproducible synthesis and surface functionalization with desired moieties. A variety of methods now exist that allow fabrication and chemical manipulation of their structure and resulting properties. This review article provides an overview and a discussion of synthetic methodologies to a diverse range of gold nanoshells, and a brief summary of surface functionalization and characterization methods employed to evaluate their overall composition. View Full-Text
Keywords: gold nanoshells; gold nanoshell synthesis; cored gold nanoshells; hollow gold nanoshells; template galvanic replacement method gold nanoshells; gold nanoshell synthesis; cored gold nanoshells; hollow gold nanoshells; template galvanic replacement method

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Wang, Y.-C.; Rhéaume, É.; Lesage, F.; Kakkar, A. Synthetic Methodologies to Gold Nanoshells: An Overview. Molecules 2018, 23, 2851.

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