Next Article in Journal
Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation
Next Article in Special Issue
Inhibitory Effect of Camptothecin against Rice Bacterial Brown Stripe Pathogen Acidovorax avenae subsp. avenae RS-2
Previous Article in Journal
Synthesis and Spectral Characterization of Benzo-[6,7][1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivatives
Previous Article in Special Issue
Quantitative Determination of Alkaloids in Lotus Flower (Flower Buds of Nelumbo nucifera) and Their Melanogenesis Inhibitory Activity
Article Menu
Issue 8 (August) cover image

Export Article

Open AccessArticle
Molecules 2016, 21(8), 968;

Indole Alkaloids from the Leaves of Nauclea officinalis

Department of Pharmacy, School of Medicine, Shenzhen University, Shenzhen 518060, China
Author to whom correspondence should be addressed.
Academic Editor: Michael Wink
Received: 25 June 2016 / Revised: 18 July 2016 / Accepted: 20 July 2016 / Published: 23 July 2016
(This article belongs to the Special Issue Diversity of Alkaloids)
Full-Text   |   PDF [1383 KB, uploaded 23 July 2016]   |  


Three new indole alkaloids, named naucleamide G (1), and nauclealomide B and C (5 and 6), were isolated from the n-BuOH-soluble fraction of an EtOH extract of the leaves of Nauclea officinalis, together with three known alkaloids, paratunamide C (2), paratunamide D (3) and paratunamide A (4). The structures with absolute configurations of the new compounds were identified on the basis of 1D and 2D NMR, HRESIMS, acid hydrolysis and quantum chemical circular dichroism (CD) calculation. According to the structures of isolated indole alkaloids, their plausible biosynthetic pathway was deduced. View Full-Text
Keywords: indole alkaloids; Nauclea officinalis; biosynthetic pathway indole alkaloids; Nauclea officinalis; biosynthetic pathway

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material


Share & Cite This Article

MDPI and ACS Style

Fan, L.; Liao, C.-H.; Kang, Q.-R.; Zheng, K.; Jiang, Y.-C.; He, Z.-D. Indole Alkaloids from the Leaves of Nauclea officinalis. Molecules 2016, 21, 968.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top