Topical Collection "Proteins and Protein-Ligand Interactions"

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A topical collection in International Journal of Molecular Sciences (ISSN 1422-0067). This collection belongs to the section "Biochemistry, Molecular Biology and Biophysics".

Editors

Collection Editor
Dr. Tatyana Karabencheva-Christova
Faculty of Health and Life Sciences, Department of Applied Sciences, Northumbria University, UK
Website: http://www.northumbria.ac.uk/sd/academic/lifesciences/ad/biomed/staff/tatyana_kc/
E-Mail: tatyana.karabencheva-christova@northumbria.ac.uk
Interests: computational chemical biology; enzyme mechanisms; catalytic activity and inhibition; computer-aided drug design; conformational dynamics of proteins and nucleic acids; biomolecular spectroscopy; bioinorganic enzymology

Collection Editor
Dr. Christo Z. Christov
Senior Lecturer in Computational Biochemistry Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University Ellison Building, Newcastle-upon-Tyne, NE1 8ST, UK
Website: http://www.northumbria.ac.uk/sd/academic/lifesciences/ad/biomed/staff/cchristov/
E-Mail: christo.christov@northumbria.ac.uk
Phone: +44 191 243 7964
Fax: +44 191 227 3519
Interests: computational biomolecular science; enzyme mechanisms; protein conformational dynamics; biomolecular spectroscopy; combined quantum mechanical and molecular mechanical methods (QM/MM); quantum chemistry; molecular dynamics; protein-ligands interactions; bioinorganic electronic structure and mechanisms

Topical Collection Information

Dear Colleagues,

Proteins are biopolymers present in all living cells/organisms that take part in basically all processes in life by exerting extremely broad functional versatility such us structural, catalytic, signaling, transportational and regulatory.

All protein functions are realized by highly specific and highly effective protein-ligand interactions, where ligands can be either other protein molecules, nucleic acids, lipids, small molecules, substrates, allosteric modulators, inhibitors or some drugs. Indeed the specificity of protein-ligand interactions and their regulatory mechanisms are responsible for normal cell functionality and alterations might lead to pathological processes. Knowledge about the nature of those interactions at the atomistic level and the impact of the conformational flexibility and mutational effects on them is crucially important for understanding the molecular nature of cell processes and will contribute to the fields of drug design and biotechnology.

This collection of IJMS aims to present a tribune to broad range state-of-the-art experimental or computational studies or their synergetic combination for understanding protein-ligand interactions in their very broad context. We are also looking for contributions underlining the impact of the investigated processes in biomedicine and molecular pathology as well as applications of protein-ligands interactions in biotechnology and food industry.

Dr. Tatyana Karabencheva-Christova
Dr. Christo Z. Christov
Collection Editors

Manuscript Submission Information

Manuscripts for the topical collection can be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on this website. The topical collection considers regular research articles, short communications and review articles. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs).

Keywords

  • protein
  • protein-protein interactions
  • protein-ligand interactions
  • protein-lipid complexes
  • protein-nucleic acids interactions
  • enzyme inhibition
  • drug design
  • computational modelling
  • docking, binding studies
  • QSAR

Published Papers (34 papers)

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2014  ( 20 papers )


2013  ( 14 papers )


2014
by , ,  and
Int. J. Mol. Sci. 2014, 15(9), 16787-16799; doi:10.3390/ijms150916787
Received: 5 June 2014; in revised form: 3 September 2014 / Accepted: 9 September 2014 / Published: 22 September 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(9), 15122-15145; doi:10.3390/ijms150915122
Received: 24 April 2014; in revised form: 30 July 2014 / Accepted: 12 August 2014 / Published: 27 August 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(7), 12731-12749; doi:10.3390/ijms150712731
Received: 7 May 2014; in revised form: 23 June 2014 / Accepted: 14 July 2014 / Published: 18 July 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(7), 11783-11798; doi:10.3390/ijms150711783
Received: 31 March 2014; in revised form: 29 May 2014 / Accepted: 29 May 2014 / Published: 2 July 2014
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by , , , , ,  and
Int. J. Mol. Sci. 2014, 15(6), 10199-10214; doi:10.3390/ijms150610199
Received: 19 March 2014; in revised form: 12 May 2014 / Accepted: 23 May 2014 / Published: 6 June 2014
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by  and
Int. J. Mol. Sci. 2014, 15(6), 10018-10033; doi:10.3390/ijms150610018
Received: 16 February 2014; in revised form: 26 May 2014 / Accepted: 27 May 2014 / Published: 4 June 2014
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by , ,  and
Int. J. Mol. Sci. 2014, 15(6), 9628-9643; doi:10.3390/ijms15069628
Received: 3 April 2014; in revised form: 17 April 2014 / Accepted: 20 May 2014 / Published: 30 May 2014
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by , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(6), 9209-9223; doi:10.3390/ijms15069209
Received: 30 March 2014; in revised form: 9 May 2014 / Accepted: 12 May 2014 / Published: 26 May 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(5), 7594-7610; doi:10.3390/ijms15057594
Received: 7 February 2014; in revised form: 4 April 2014 / Accepted: 17 April 2014 / Published: 5 May 2014
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by , , , , ,  and
Int. J. Mol. Sci. 2014, 15(5), 7651-7666; doi:10.3390/ijms15057651
Received: 30 March 2014; in revised form: 18 April 2014 / Accepted: 21 April 2014 / Published: 5 May 2014
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by , , , ,  and
Int. J. Mol. Sci. 2014, 15(5), 7513-7536; doi:10.3390/ijms15057513
Received: 30 March 2014; in revised form: 18 April 2014 / Accepted: 21 April 2014 / Published: 30 April 2014
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by , , , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(5), 7225-7249; doi:10.3390/ijms15057225
Received: 22 November 2013; in revised form: 10 January 2014 / Accepted: 15 January 2014 / Published: 25 April 2014
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by ,  and
Int. J. Mol. Sci. 2014, 15(4), 6797-6814; doi:10.3390/ijms15046797
Received: 25 January 2014; in revised form: 3 April 2014 / Accepted: 4 April 2014 / Published: 22 April 2014
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by  and
Int. J. Mol. Sci. 2014, 15(4), 6717-6724; doi:10.3390/ijms15046717
Received: 2 February 2014; in revised form: 24 March 2014 / Accepted: 9 April 2014 / Published: 21 April 2014
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by , , , ,  and
Int. J. Mol. Sci. 2014, 15(4), 5221-5232; doi:10.3390/ijms15045221
Received: 25 January 2014; in revised form: 15 March 2014 / Accepted: 17 March 2014 / Published: 25 March 2014
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by ,  and
Int. J. Mol. Sci. 2014, 15(3), 3580-3595; doi:10.3390/ijms15033580
Received: 27 January 2014; in revised form: 17 February 2014 / Accepted: 18 February 2014 / Published: 27 February 2014
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by , ,  and
Int. J. Mol. Sci. 2014, 15(2), 2622-2645; doi:10.3390/ijms15022622
Received: 18 December 2013; in revised form: 17 January 2014 / Accepted: 21 January 2014 / Published: 14 February 2014
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by , , , , ,  and
Int. J. Mol. Sci. 2014, 15(2), 2431-2453; doi:10.3390/ijms15022431
Received: 4 December 2013; in revised form: 10 January 2014 / Accepted: 22 January 2014 / Published: 11 February 2014
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by , , , ,  and
Int. J. Mol. Sci. 2014, 15(2), 2359-2367; doi:10.3390/ijms15022359
Received: 13 December 2013; in revised form: 18 January 2014 / Accepted: 28 January 2014 / Published: 7 February 2014
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by , ,  and
Int. J. Mol. Sci. 2014, 15(1), 438-455; doi:10.3390/ijms15010438
Received: 28 November 2013; in revised form: 19 December 2013 / Accepted: 27 December 2013 / Published: 2 January 2014
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2013
by , , ,  and
Int. J. Mol. Sci. 2014, 15(1), 141-158; doi:10.3390/ijms15010141
Received: 6 November 2013; in revised form: 12 December 2013 / Accepted: 17 December 2013 / Published: 23 December 2013
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by , , , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(1), 29-43; doi:10.3390/ijms15010029
Received: 28 October 2013; in revised form: 28 November 2013 / Accepted: 6 December 2013 / Published: 20 December 2013
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by , ,  and
Int. J. Mol. Sci. 2014, 15(1), 75-99; doi:10.3390/ijms15010075
Received: 1 November 2013; in revised form: 5 December 2013 / Accepted: 12 December 2013 / Published: 20 December 2013
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by , , , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(12), 23955-23979; doi:10.3390/ijms141223955
Received: 13 September 2013; in revised form: 13 November 2013 / Accepted: 19 November 2013 / Published: 9 December 2013
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by , , , , ,  and
Int. J. Mol. Sci. 2013, 14(12), 23244-23256; doi:10.3390/ijms141223244
Received: 31 July 2013; in revised form: 31 October 2013 / Accepted: 11 November 2013 / Published: 25 November 2013
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by , , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(11), 22845-22856; doi:10.3390/ijms141122845
Received: 12 September 2013; in revised form: 6 November 2013 / Accepted: 7 November 2013 / Published: 20 November 2013
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by , ,  and
Int. J. Mol. Sci. 2013, 14(11), 22331-22345; doi:10.3390/ijms141122331
Received: 9 October 2013; in revised form: 1 November 2013 / Accepted: 5 November 2013 / Published: 13 November 2013
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by  and
Int. J. Mol. Sci. 2013, 14(11), 21551-21560; doi:10.3390/ijms141121551
Received: 26 September 2013; in revised form: 16 October 2013 / Accepted: 22 October 2013 / Published: 31 October 2013
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by , ,  and
Int. J. Mol. Sci. 2013, 14(10), 19556-19586; doi:10.3390/ijms141019556
Received: 11 July 2013; in revised form: 14 August 2013 / Accepted: 10 September 2013 / Published: 26 September 2013
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by , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(9), 19067-19085; doi:10.3390/ijms140919067
Received: 15 August 2013; in revised form: 6 September 2013 / Accepted: 11 September 2013 / Published: 16 September 2013
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by , , ,  and
Int. J. Mol. Sci. 2013, 14(8), 16836-16850; doi:10.3390/ijms140816836
Received: 15 July 2013; in revised form: 31 July 2013 / Accepted: 6 August 2013 / Published: 15 August 2013
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by , , , , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(7), 15121-15140; doi:10.3390/ijms140715121
Received: 14 May 2013; in revised form: 2 July 2013 / Accepted: 4 July 2013 / Published: 22 July 2013
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by
Int. J. Mol. Sci. 2013, 14(7), 14408-14425; doi:10.3390/ijms140714408
Received: 24 May 2013; in revised form: 27 June 2013 / Accepted: 2 July 2013 / Published: 11 July 2013
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by , , , ,  and
Int. J. Mol. Sci. 2013, 14(7), 12914-12930; doi:10.3390/ijms140712914
Received: 2 May 2013; in revised form: 7 June 2013 / Accepted: 7 June 2013 / Published: 24 June 2013
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Last update: 9 May 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert