Gastrointestinal and Metabolic Diseases: From Mechanisms to Surgery

Topic Information

Dear Colleagues,

Gastrointestinal and metabolic diseases represent a broad and complex group of disorders involving the digestive tract, associated organs, and systemic metabolic regulation, including inflammatory, neoplastic, functional, and obesity-related conditions. These diseases remain a major global health burden and continue to stimulate growing interest in their physiological and pathophysiological mechanisms, including neuroendocrine signaling, inflammation, barrier dysfunction, gut microbiota interactions, and metabolic regulation.

At the same time, gastrointestinal surgery has evolved considerably through minimally invasive and robotic approaches, improved perioperative management, and increasing integration with translational and precision medicine. Surgery is no longer viewed solely as a technical intervention, but also as a physiological and metabolic modulator with important endocrine, inflammatory, immunological, and microbiota-related effects.

This Topic aims to provide a multidisciplinary platform for research bridging gastrointestinal physiology, pathophysiology, metabolic regulation, and surgery. Particular attention will be given to bariatric and metabolic surgery, while also addressing a broad spectrum of benign and malignant gastrointestinal diseases. We welcome high-quality contributions that explore mechanisms of disease, surgical innovation, patient stratification, perioperative optimization, and clinically relevant outcomes.

In this Topic, original research articles and reviews are welcome. Research topics may include, but are not limited to, the following:

• Physiological and pathophysiological mechanisms in gastrointestinal and metabolic diseases
• Translational links between gastrointestinal physiology, metabolic regulation, and surgical practice
• Surgery as a metabolic and endocrine modulator
• Bariatric and metabolic surgery: mechanisms, indications, and outcomes
• Gut microbiota and host responses in gastrointestinal and metabolic disease
• Inflammatory and immunological pathways relevant to digestive and metabolic surgery
• Advances in minimally invasive and robotic gastrointestinal surgery
• Surgical treatment of benign and malignant gastrointestinal diseases
• Perioperative optimization, enhanced recovery, and functional outcomes
• Biomarkers, predictive models, and personalized approaches in gastrointestinal and metabolic diseases. 

We are pleased to invite researchers and clinicians to contribute their latest findings and perspectives to this Topic.

We look forward to receiving your contributions. 

Dr. Alin Constantin Pînzariu
Prof. Dr. Ionela Lacramioara Serban
Prof. Dr. Daniel Timofte
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Current Issues in Molecular Biology cimb	3.0	5.0	1999	16.3 Days	CHF 2200	Submit
Gastrointestinal Disorders gastrointestdisord	0.8	2.1	2019	22.2 Days	CHF 1400	Submit
International Journal of Molecular Sciences ijms	4.9	10.0	2000	17.8 Days	CHF 2900	Submit
Surgeries surgeries	1.1	1.8	2020	24.4 Days	CHF 1400	Submit

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