Nanomaterials in Biomedicine: Therapeutic Delivery, Diagnostics, and Beyond

Dear Colleagues,

Nanomaterials have emerged as powerful tools at the forefront of modern biomedicine, offering unprecedented capabilities for improving human health. This Topic will synthesize the multifaceted roles of nanomaterials across therapeutic delivery, diagnostics, and emerging biomedical applications. It will present advanced nanocarriers designed for targeted drug and gene delivery, highlighting strategies that enhance bioavailability and controlled release and minimize systemic toxicity. In the realm of diagnostics, this Topic will include reports on nanoscale probes and contrast agents that have significantly improved the sensitivity and specificity of imaging and point-of-care detection methods. The integration of therapeutic and diagnostic functions into single nanoplatforms (theranostics) enabling real-time monitoring and personalized treatment strategies will be also discussed. Beyond these well-established domains, cutting-edge applications, including tissue engineering scaffolds, antimicrobial surfaces, and nano-enabled immunotherapies, will also be acknowledged. Critical considerations regarding biocompatibility, toxicity, and regulatory challenges will be addressed to underscore the path toward clinical translation. Finally, it will reflect on future directions, emphasizing the convergence of nanotechnology with artificial intelligence and precision medicine to shape the next generation of biomedical innovations.

Prof. Dr. Hans Bäumler
Prof. Dr. Radostina Georgieva
Topic Editors