Search Results (4,862)

Oxidative stress is a key contributor to aging and chronic diseases, highlighting the need for safe and effective natural antioxidants. Monascus yellow pigments (MYPs) and ginsenoside Rg3 exhibit antioxidant activity, but their applications are restricted by low solubility and limited natural abundance. In this research, a bidirectional liquid fermentation system of Monascus ruber using ginseng decoction was established for the simultaneous production of water-soluble MYPs (WSMYPs) and ginsenoside Rg3. Process conditions were optimized to enhance the yields and the antioxidant activity of the system. Antioxidant assays and H₂O₂-induced RAW264.7 cell models confirmed that WSMYPs were strongly correlated with antioxidant capacity, with ABTS and DPPH scavenging activities showing 2.28-fold and 3.33-fold increases, respectively, compared to the control. Their combination with Rg3 exerted synergistic protective effects by enhancing the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT). Network pharmacology and molecular docking further revealed that Monapurone C, a representative WSMYP, and Rg3 act through a multi-target, multi-pathway antioxidant network involving signaling pathways such as PI3K-Akt. This study demonstrates a cost-effective strategy for co-producing WSMYPs and Rg3, providing new insights into the value-added utilization of edible and medicinal resources. Full article

As the energy and power sector transitions toward clean and low-carbon development, the installed capacity of renewable energy sources such as wind and photovoltaic power has been rapidly increasing. Wind–solar hydrogen production via water electrolysis can enhance renewable energy utilization and enable the supply of green hydrogen. Meanwhile, the $H_2/C{O}_2$ molar ratio in the syngas produced by conventional biomass gasification generally cannot directly meet the 2:1 stoichiometric requirement for methanol synthesis. To address this issue, this paper proposes an off-grid coordinated system integrating wind–solar hydrogen production and biomass gasification for methanol synthesis. The system incorporates multi-operating-condition constraints of electrolyzers, coordinated regulation between electrochemical energy storage and hydrogen storage, and coordinated matching between biomass gasification and the water–gas shift reaction. Based on the system energy and material balance, a mixed-integer linear programming (MILP) model is formulated with the objective of minimizing the annualized total cost and is solved using the Gurobi solver in the MATLAB environment. To highlight the roles of HES and the WGS reaction, four comparative scenarios are designed for validation. The results show that the system with an annual methanol production capacity of 100,000 tons achieves an annualized total cost of 318 million CNY, with a wind–solar utilization rate of 98.86%. The system is configured with 12 electrolyzers of 5 MW each. The biomass consumption per ton of methanol is 3.06, and the $C{O}_2$ emissions per ton of methanol are 2.37. Finally, a sensitivity analysis of the levelized methanol cost (LCOM) was conducted, providing guidance for cost reduction in green methanol production. Full article

Energy-intensive processes such as flexographic printing, extrusion coating, slitting, compressed air generation, and chilled water production make liquid carton packaging manufacturing a major electricity consumer, increasing the need for cost-effective and sustainable energy solutions. This study evaluates the real-world performance of a 679 kWp grid-tied solar photovoltaic (PV) system integrated at the 11 kV level in a liquid carton packaging factory in Nairobi, Kenya, operating under regulatory export control constraints that require full on-site consumption of PV generation. Using measured operational data from energy monitoring platforms, including Sunny Portal, 1.31.8 Schneider EcoStruxure, and Sphera Cloud 8.17.2, system performance was assessed in accordance with IEC 61724-1, focusing on final yield, capacity utilization factor, grid offset contribution, and carbon emissions reduction. The results show that the system generated 617 MWh over the assessment period, corresponding to an average daily final yield of 2.49 kWh/kWp·day and a capacity utilization factor of 10.38%. On-site PV generation supplied approximately 17% of the plant’s annual electricity demand and avoided about 277.7 t CO₂ emissions. Performance benchmarking against comparable installations in Kenya, Morocco, Malaysia, Senegal, and Uzbekistan indicates that the lower observed yield is primarily driven by curtailment and industrial load-matching limitations rather than inadequate solar resource or component inefficiency. The findings demonstrate that meaningful electricity cost savings and emissions reductions can be achieved in energy-intensive manufacturing environments despite export restrictions while highlighting the importance of improved load alignment and data-driven operational strategies to enhance PV utilization. Full article

The development of biocompatible functional nanostructures has emerged as a key driver in advancing nanomedicine, environmental remediation, and sustainable energy technologies. However, conventional synthesis methods often rely on toxic reagents, hazardous solvents, and energy-intensive processes, raising significant concerns regarding environmental impact and biological safety. In this context, green synthesis has gained increasing attention as a sustainable alternative, utilizing biological systems, renewable resources, and environmentally benign solvents to produce functional nanomaterials. This mini-review provides an overview of recent advances in the green synthesis of organic, inorganic, and hybrid nanostructures, highlighting their physicochemical properties and functional performance. Particular emphasis is placed on their applications in nanomedicine, including drug delivery, bioimaging, antimicrobial and anticancer therapies, and theranostic platforms. Additionally, their roles in environmental applications, such as pollutant degradation and water treatment, and in energy-related systems, including catalysis, solar energy conversion, and energy storage, are discussed with selected representative examples. Despite significant progress, key challenges remain, including limited mechanistic understanding, reproducibility issues, scalability constraints, and uncertainties related to long-term toxicity and environmental impact. Addressing these limitations will be essential for the safe and large-scale implementation of green nanotechnology. Overall, the integration of green chemistry principles with advanced nanomaterial design offers a promising pathway toward the development of multifunctional, sustainable, and high-performance nanostructures capable of addressing global health, environmental, and energy challenges. Full article

In recent years, accelerated industrialization has made water pollution a major challenge, bisphenol pollutants being one of the most typical examples. Advanced oxidation processes (AOPs) based on peroxymonosulfate (PMS) activation have been applied in environmental remediation due to their broad applicability and high pollutant removal efficiency. The key to AOPs lies in developing low-cost, highly active catalysts. This study utilized waste biomass of baijiu distillers’ grains (DSGs) as precursor to prepare biochar materials for bisphenol pollutant removal. Through high-temperature pyrolysis at 900 °C for 2 h in the presence of NaCl and KCl as activator, biochar-based materials (BC-x) were prepared, which possessed advantageous features of large specific surface area and high nitrogen doping content. When applied for typical bisphenol pollutant removal, the selected BC-900 biochar exhibited almost 100% bisphenol AF (BPAF) removal efficiency after a 30 min adsorption and following a 5 min PMS activation process under reaction conditions of 200 mg L⁻¹ of BC-900, 200 mg L⁻¹ of PMS, and 20 mg L⁻¹ of BPAF. Reactive species of sulfate radicals (SO₄⦁⁻), hydroxyl radicals (⦁OH) and singlet oxygen (¹O₂) were responsible for BPAF degradation, among which ¹O₂ played the major role. Further toxicity prediction of the BPAF degradation intermediate products implied the low ecological risk of the constructed BC-900/PMS catalytic system for BPAF removal. The findings in this study may provide useful guidance for waste biomass conversion and organic contamination remediation in water. Full article

Cocoa husk tea has gained attention as a value-added beverage from cocoa processing by-products, due to its potential content of bioactive compounds associated with health benefits. However, rapid and reliable analytical methods for the simultaneous determination of methylxanthines and flavanols in this matrix remain limited. This study aimed to develop and validate a rapid HPLC–PDA method for the simultaneous determination of methylxanthines and selected flavanols in cocoa husk tea. Separation was performed using a Zorbax 300SB-C18 with a gradient system of acetic acid, water and acetonitrile, and detection at 280 nm. The method enabled separation of theobromine, caffeine, catechin, epicatechin, procyanidin B1, and procyanidin B2 within 15 min. Validation followed ICH Q2(R2) guidelines, demonstrating satisfactory linearity, sensitivity, accuracy, and precision. The method was applied to ten commercial cocoa husk tea products from Thailand. Theobromine was the predominant methylxanthine (10.483–16.027 mg g⁻¹), whereas caffeine was lower (0.923–1.909 mg g⁻¹), while flavanol contents varied among samples. These findings demonstrate that the developed method provides a rapid and reliable approach for the analysis and quality assessment of cocoa husk tea products and may support the further utilization of cocoa by-products in the functional beverage industry. Full article

This study explores the use of metallurgical slag extracts as a liquid mineral fertilizer for maize cultivation. Slag samples were obtained from the former lead smelter in Shymkent and the Zhezkent Mining and Processing Plant. Elemental analysis identified the slag from the second storage area of the Shymkent smelter as the least contaminated with potentially toxic elements and enriched in macro- and micronutrients. Slag extraction was conducted via chemical leaching using potassium sulfate and ammonia solutions in a hydrogen peroxide medium, yielding Cu²⁺ and Zn²⁺ concentrations of 423.751 mg/L and 86.649 mg/L, respectively. The resulting extracts were diluted with distilled water at a ratio of 1:10 (potassium sulfate extract) and 1:200 (ammonia extract) and applied to assess early seed development and subsequent maize yield. Seed germination rates were comparable to those of the control group (100%). After 90 days of growth, maize plants treated with the ammonia-based extract showed positive effects on root system development, stem growth, and cob formation. The concentration of potentially toxic elements in the dry plant biomass remained within permissible limits. These findings demonstrate the potential for the safe agricultural use of these extracts while ensuring the rational utilization of industrial waste. Full article

Freshwater snails, specifically those belonging to the genus Bellamya, are increasingly recognized as important components of sustainable aquaculture and aquatic ecosystem management. This review synthesizes current knowledge on their ecological roles, aquaculture practices, utilization, and associated risks to evaluate their potential as a multifunctional resource. Available evidence shows that Bellamya species function as bioindicators of environmental change and contribute to water purification through grazing, nutrient cycling, and interactions with aquatic plants. In aquaculture, diverse production systems, including rice–snail co-culture and pond-based farming, have been developed, demonstrating high resource-use efficiency and economic value. In addition to their nutritional importance as a protein source, freshwater snails provide opportunities for value-added products in food, biomaterials, and health-related applications. However, challenges remain, including parasite transmission, the bioaccumulation of environmental pollutants, genetic resource degradation, and ecological carrying capacity constraints under intensive farming. Future development depends on advances in breeding, nutrition, and intelligent farming technologies, as well as improved environmental monitoring and regulatory frameworks. Overall, freshwater snail aquaculture represents a promising pathway for integrating food production with ecosystem restoration, but its sustainable expansion requires coordinated efforts in research, management, and industry development. Full article

This study develops a ternary Fe-based geopolymer system composed of metakaolin (MK), red mud (RM), and fly ash (FA) for the preparation of sustainable water-retaining subgrade materials for sponge-city roadbed applications. Unlike conventional formulations primarily designed for structural strength or rapid permeability, the proposed MK–FA–RM system was designed to improve water-storage capacity while maintaining adequate mechanical support and environmental compatibility. In this ternary system, MK provides highly reactive aluminosilicate species for geopolymer network formation, RM introduces Fe-bearing phases and enhances industrial solid-waste utilization, and FA contributes to particle packing, workability, and resource efficiency. A constrained ternary mixture design implemented using Design-Expert software was adopted to optimize precursor proportions. Within the investigated compositional range, the fitted first-order mixture model showed acceptable statistical adequacy for preliminary composition screening (R² = 0.86). The optimal blend (60% MK, 30% RM, and 10% FA) achieved a 7-day compressive strength of 8.37 MPa and a water retention rate of 35.3% under ambient curing conditions, satisfying the strength requirement considered for the target subgrade/base-layer application. Microstructural and phase analyses suggest that the synergistic interaction of the three precursors promoted Fe-modified aluminosilicate gel formation together with conventional geopolymer gel products, while improving matrix continuity and preserving interconnected pore space for water storage. This multiscale structural effect helps explain how the material achieved a balance between water retention capacity and mechanical support. Under the tested conditions, the material maintained acceptable residual strength after short-term exposure to water, acid, and sulfate-containing solutions. Life-cycle assessment indicated a 70% reduction in CO₂ emissions compared with ordinary Portland cement, while pilot-scale cost analysis showed a 39% lower production cost than MetaMax-based geopolymer materials. Pilot-scale application further demonstrated the constructability and water-regulation potential of the material in practical environments. Overall, the proposed ternary Fe-based geopolymer demonstrates that Fe-rich industrial wastes can be engineered into low-carbon and economically viable water-retaining subgrade materials that balance hydraulic regulation, structural adequacy, and sustainability. Nevertheless, long-term durability, cyclic loading performance, and direct nanoscale characterization of Fe-bearing gel evolution still require further investigation. Full article

This study characterizes novel cross-linked polymeric composites based on bisphenol A glycerolate dimethacrylate (BPA.DM) as the primary matrix, incorporating 1-vinyl-2-pyrrolidone (NVP) or 2-hydroxyethyl methacrylate (HEMA) as active diluents, and modified with antimicrobial agents: zinc oxide (ZnO), copper(II) sulfate (CuSO₄), nanosilver (Ag), and benzethonium chloride (BEN). Release kinetics of active components into water and LH medium were measured over 20 days using HPLC (bisphenol A, benzethonium chloride), GF AAS (Cu, Zn, Ag), and GC–MS, revealing highest silver release from HEMA+Ag composites (1671 µg/L), substantial copper release from HEMA (354 mg/L) and NVP (319 mg/L) systems, while benzethonium chloride exhibited significantly lower migration. The effect of NVP- and HEMA-containing composites on the metabolism of the Cerrena unicolor was also assessed. Scanning electron microscopy (SEM) and optical profilometry confirmed extensive surface degradation by C. unicolor mycelium, manifesting as cracks, increased porosity, and altered surface across HEMA- and NVP-based composites after 21-day incubation. Biochemical analysis of the fungus post-culture liquids demonstrated that both composite types markedly enhanced extracellular laccase activity at all tested time points (7, 14, 21 days), with ethanol-sterilized samples inducing a slower-migrating laccase isoform identified via zymography. These materials also increased total protein concentration and superoxide anion radical levels while reducing phenolic compounds relative to controls. The findings demonstrate that antimicrobial-modified BPA.DM composites not only undergo controlled biodegradation by C. unicolor but crucially serve as potential laccase inducers, highlighting their dual utility in bioactive material design and fungal enzyme biotechnology. Full article

Coal mine methane (CMM) separation faces significant challenges due to high humidity and multicomponent conditions, under which the selective adsorption performance of CH₄ is substantially degraded compared with idealized laboratory scenarios. This review systematically analyzes the fundamental causes of this discrepancy by integrating water vapor occupation, competitive adsorption, and structural constraints into a unified framework. Water molecules preferentially occupy high-energy adsorption sites and reconstruct the interfacial energy landscape, while strongly adsorbing components such as CO₂ further suppress CH₄ uptake through competitive displacement. These coupled effects lead to a pronounced deviation between theoretical adsorption capacity and actual separation performance. To address this issue, this work proposes an evaluation paradigm centered on effective working capacity, which reflects the practically recoverable CH₄ under cyclic operation rather than equilibrium limits. The applicability of this framework is demonstrated through comparative analysis across different adsorbent systems, highlighting the critical roles of moisture resistance, structural stability, and competitive resilience. Finally, key material design strategies and process-level optimization approaches are discussed to enhance sustainable CH₄ separation under realistic conditions. This review provides a process-oriented perspective for bridging the gap between material performance and engineering application in CMM utilization. Full article

Ozone micro- and nanobubbles have emerged as a promising platform for advanced oxidation processes owing to their distinctive physicochemical characteristics, including exceptional stability, prolonged gas residence time, and highly active gas–liquid interfaces. Compared with conventional ozonation, micro/nanobubble-assisted systems significantly enhance ozone dissolution and utilization efficiency. They achieve this by creating a unique interfacial microenvironment that promotes localized and sustained oxidative reactions. Increasing evidence suggests that ozone oxidation is not dominated solely by homogeneous bulk-phase reactions but is strongly coupled with processes occurring at the bubble/water interface, particularly hydroxyl radical generation and surface-localized oxidation. This review provides an application-oriented overview of ozone micro/nanobubble technology by summarizing representative preparation methods and characterization techniques, elucidating their distinctive interfacial physicochemical properties, and critically examining their performance in oxidative cleaning, microbial inactivation, and complex environmental remediation. Special emphasis is placed on interpreting these phenomena from the perspective of gas–liquid reactions and surface-induced radical generation, with the aim of establishing a unified mechanistic framework that bridges fundamental properties with engineering performance. Finally, current challenges and future research directions for translating ozone micro/nanobubble systems into large-scale and long-term applications are discussed. Full article

Decarbonizing HVAC in hot–arid regions is challenging for natatoriums because year-round cooling must be delivered alongside stringent dehumidification and occasional heating under high ambient temperatures. In this paper, a fully renewable system has been developed and evaluated for an indoor swimming pool located in Abu Dhabi with a 679 m² swimming pool hall designed to accommodate 200 pool users. The hybrid system includes a high-temperature linear Fresnel reflector (LFR) solar field, stratified thermal energy storage (TES), a single-effect LiBr–H₂O absorption chiller for cooling, a water-to-water heat pump as a backup system for the stability of cooling and heating rates, and a photovoltaic (PV) system to offset the ancillary equipment power input of the hybrid system. The system performance was simulated and validated by using hourly data from Abu Dhabi. Optimization of design/operation parameters was carried out by a multi-objective genetic algorithm to achieve the maximum coefficient of performance (COP) and the minimum levelized cost of cooling (LCOE). The initial COP and LCOE were 0.701 and 0.037 $/kWh, respectively. They were optimized to 0.825 and 0.0254 $/kWh, respectively. The annual energy balance revealed a synergistic operation of the solar field, TES, and heat pump. The lifecycle assessment was utilized to compare the proposed hybrid system with the conventional vapor-compression systems in terms of energy, cost, and CO₂ emissions, in which the proposed system proved superior over conventional systems with a positive net present value (NPV) and net zero carbon emissions. Full article

To address the key problems of low-frequency oscillation and insufficient regulation accuracy at the Point of Common Coupling (PCC) in hydro–wind–photovoltaic hybrid systems, which are caused by the randomness of wind and photovoltaic output, the water-hammer effect of hydropower units, and multi-source power coupling, a joint control strategy based on Fractional-Order Proportional Integral Derivative (FOPID) and Co-evolutionary Multi-objective Particle Swarm Optimization (CMOPSO) is proposed. First, a small-signal transfer function model of the system covering photovoltaic inverters, doubly fed induction generators (DFIGs), hydropower units and voltage-source converter-based high-voltage direct current (VSC-HVDC) converter stations is established to accurately characterize the water-hammer effect and multi-source dynamic coupling characteristics. Second, a Caputo-type FOPID controller is designed. Compared with traditional integer-order controllers with limited tuning flexibility, the FOPID controller utilizes its five degrees of freedom to address specific multi-source coupling challenges. This precisely compensates for the non-minimum phase lag caused by the water-hammer effect in hydropower units via the fractional derivative link, and effectively smooths the impact of stochastic wind–solar fluctuations on PCC voltage through the memory characteristics of the fractional integral link. This multi-parameter regulation mechanism prevents a trade-off between response speed and overshoot suppression, achieving effective decoupling of complex multi-source dynamic interactions. Third, a dual-objective optimization framework with the Integral of Time-weighted Absolute Error (ITAE) and Oscillatory Disturbance Risk Index (ODRI) as the objectives is constructed. The multi-population co-evolution mechanism of the CMOPSO algorithm is adopted to solve the Pareto-optimal solution set, realizing the coordinated optimization of dynamic response accuracy and oscillation instability risk. Finally, comparative simulations are carried out on the Simulink platform with traditional PI/FOPI controllers and optimization algorithms such as Multi-objective Particle Swarm Optimization based on the Decomposition/Simple Indicator-Based Evolutionary Algorithm (MPSOD/SIBEA). The results show that the proposed strategy can effectively suppress low-frequency oscillations in the range of 0~30 Hz. Compared with the traditional PI controller, the PCC voltage overshoot is reduced by more than 40%, the oscillation decay time is shortened by 33%, the ITAE and ODRI indices are decreased by 12.58% and 2.47%, respectively, and the stability of DC bus voltage is significantly improved. Its robustness and comprehensive control performance are superior to existing methods, providing an efficient and stable control scheme for power electronics-dominated complex new energy grid-connected systems. Full article

Alternate wetting and drying (AWD) is a crucial water-saving irrigation strategy in rice production, yet its regulatory mechanisms during drought–rewatering cycles remain unclear, particularly across recovery stages. Using a polyethylene glycol (PEG-6000) hydroponic system, we analyzed physiological, metabolomic, and transcriptomic responses of Oryza sativa L. ssp. japonica under control, continuous drought, and rewatering treatments. The net photosynthetic rate (P_n) recovered within one day after rewatering, and subsequently exceeded control levels, indicating a photosynthetic compensatory effect. In contrast, instantaneous water-use efficiency (WUE) showed only a transient increase before declining thereafter and remaining lower than under continuous drought, revealing an asynchronous recovery in which carbon assimilation precedes the recovery of transpiration. Metabolomic analysis indicated a shift from drought-induced accumulation to recovery-driven metabolic reprogramming, with coordinated up-regulation of central carbon metabolism and chlorophyll biosynthesis. Decreases in citrate, malate, and glutamate suggested their sustained utilization to support nitrogen assimilation and chlorophyll synthesis. Transcriptomic data further revealed large-scale reprogramming during late recovery, including up-regulation of nitrogen assimilation genes (e.g., NIA, NiR), linking carbon–nitrogen coordination with photosynthetic compensation. Overall, these results demonstrate that stage-specific integration of physiological recovery, metabolic restructuring, and transcriptional regulation underlies AWD-induced efficiency and identify early rewatering as a critical window for optimizing WUE. Full article