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Search Results (626)

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Keywords = upper limb rehabilitation

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12 pages, 521 KiB  
Article
Examination of the Relationship Between Pain Intensity, Pain Perceptions, and Kinesiophobia in Patients with Non-Specific Chronic Musculoskeletal Pain
by Sofia Sgourda, Maria Loulla, Eirini Zisiopoulou, Krystalia Katsiou, Sofia Nikolaidi, Ioannis Kyrosis and Anna Christakou
Muscles 2025, 4(3), 27; https://doi.org/10.3390/muscles4030027 - 4 Aug 2025
Viewed by 97
Abstract
Chronic musculoskeletal pain negatively affects patients’ quality of life, and pain perceptions may significantly influence rehabilitation outcomes. This study investigated the relationships among pain intensity, pain perceptions, and kinesiophobia in individuals with chronic musculoskeletal pain. No previous studies have examined these variables in [...] Read more.
Chronic musculoskeletal pain negatively affects patients’ quality of life, and pain perceptions may significantly influence rehabilitation outcomes. This study investigated the relationships among pain intensity, pain perceptions, and kinesiophobia in individuals with chronic musculoskeletal pain. No previous studies have examined these variables in combination. A cross-sectional observational study was conducted with 37 participants with non-specific chronic musculoskeletal pain for at least 6 months, affecting the neck (n = 8), lower back (n = 18), upper limbs (n = 5), lower limbs (n = 5), or shoulder (n = 1). The following validated tools were used: (a) Pain Beliefs and Perceptions Inventory (PBPI), (b) the Tampa Scale for Kinesiophobia (TSK), and (c) the Short-Form McGill Pain Questionnaire (SF-MPQ). Spearman r correlation analyses were performed. Total kinesiophobia scores were positively correlated with (a) total pain intensity (McGill score) (r = 0.37, p = 0.022), (b) present pain intensity (PPI) (r = 0.52, p = 0.001), (c) pain duration (r = 0.51, p = 0.001), (d) the “mystery” factor of pain perception (r = 0.41, p = 0.013), and (e) the Visual Analogue Scale (VAS) (r = 0.42, p = 0.009). The total pain perception scores were positively associated with the “fear of injury” factor of kinesiophobia (r = 0.36, p = 0.028). The McGill pain scores were strongly correlated with both PPI (r = 0.63, p = 0.001) and VAS (r = 0.51, p = 0.001). There is a significant relationship between pain perception and kinesiophobia levels in patients with chronic musculoskeletal pain. Limitations of the study include a small and heterogeneous sample regarding pain localization. Further research is required using larger, more homogeneous populations to confirm the present findings. Full article
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13 pages, 551 KiB  
Article
Classifying Patient Characteristics and Determining a Predictor in Acute Stroke Patients: Application of Latent Class Analysis in Rehabilitation Practice
by Junya Uchida, Moeka Yamada, Hirofumi Nagayama, Kounosuke Tomori, Kohei Ikeda and Keita Yamauchi
J. Clin. Med. 2025, 14(15), 5466; https://doi.org/10.3390/jcm14155466 - 4 Aug 2025
Viewed by 201
Abstract
Background/Objectives: Predicting comprehensive patient characteristics is essential for optimal individualized rehabilitation plans for acute stroke patients. However, current models primarily predict single outcomes. This study aimed to assess the applicability of latent class analysis (LCA) in rehabilitation practice by identifying comprehensive characteristics [...] Read more.
Background/Objectives: Predicting comprehensive patient characteristics is essential for optimal individualized rehabilitation plans for acute stroke patients. However, current models primarily predict single outcomes. This study aimed to assess the applicability of latent class analysis (LCA) in rehabilitation practice by identifying comprehensive characteristics and associated predictors in acute stroke patients. Methods: We conducted a retrospective observational study using the Japan Association of Rehabilitation Database, including 10,270 stroke patients admitted to 37 acute-care hospitals between January 2005 and March 2016. Patients were classified using LCA based on outcomes at discharge, including Functional Independence Measure (FIM), National Institutes of Health Stroke Scale (NIHSS) subscales for upper-extremity function, length of hospitalization, and discharge destination. Predictor variables at admission included age, FIM scores, NIHSS subscales for upper-extremity function, stroke type, and daily rehabilitation volume. Results: 6881 patients were classified into nine distinct classes (class size: 4–29%). Class 1, representing the mildest cases, was noted for independent ambulation and good upper limb function. Class 2 comprised those with the most severe clinical outcome. Other classes exhibited a gradient of severity, commonly encountered in clinical practice. For instance, Class 7 included right-sided paralysis with preserved motor activities of daily living (ADLs) and modified dependence in cognitive functions, such as communication. All predictors at admission were significantly associated with class membership at discharge (p < 0.001). Conclusions: LCA effectively identified unique clinical subgroups among acute stroke patients and demonstrated that key admission variables could predict class membership. This approach offers a promising insight into targeted, personalized rehabilitation practice for acute stroke patients. Full article
(This article belongs to the Section Clinical Rehabilitation)
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13 pages, 849 KiB  
Article
Morphofunctional Profile Focusing on Strength and Ultrasound of the Upper Limbs in Female Breast Cancer Survivors: A Comparative Cross-Sectional Study Between Groups with and Without Lymphoedema and Between Ipsilateral and Contralateral Limbs
by Ana Rafaela Cardozo Da Silva, Juliana Netto Maia, Vanessa Maria Da Silva Alves Gomes, Naiany Tenório, Juliana Fernandes de Souza Barbosa, Ana Claudia Souza da Silva, Vanessa Patrícia Soares de Sousa, Leila Maria Alvares Barbosa, Armèle de Fátima Dornelas de Andrade and Diego Dantas
Biomedicines 2025, 13(8), 1884; https://doi.org/10.3390/biomedicines13081884 - 2 Aug 2025
Viewed by 300
Abstract
Background: Breast cancer is the most common neoplasm in women. Despite effective treatments, sequelae such as decreased muscle strength, upper limb dysfunction, and tissue changes are common, highlighting the need for functional assessments during rehabilitation. This study analysed the morphofunctional profile of [...] Read more.
Background: Breast cancer is the most common neoplasm in women. Despite effective treatments, sequelae such as decreased muscle strength, upper limb dysfunction, and tissue changes are common, highlighting the need for functional assessments during rehabilitation. This study analysed the morphofunctional profile of the upper limbs in breast cancer survivors, comparing muscle strength and ultrasound findings between groups with and without lymphoedema, as well as between ipsilateral and contralateral limbs. Methods: This cross-sectional study included female breast cancer survivors treated at an oncology physical therapy clinic. Muscle strength was measured using dynamometry (handgrip and arm flexor strength), and ultrasound assessed the thickness of the dermal–epidermal complex (DEC), subcutaneous tissue (SUB), and muscle (MT). Results: The upper limbs of 41 women were evaluated. No significant differences were observed between those with and without breast cancer-related lymphoedema (BCRL). When comparing the ipsilateral and contralateral limbs, significant reductions were observed in arm flexor strength (p < 0.001; 95% CI: −9.77 to −2.50), handgrip strength (p < 0.001; 95% CI: −4.10 to −1.22), and tissue thickness, with increased DEC thickness on the forearm (0.20 mm; p = 0.022) and arm flexors (0.25 mm; p < 0.001) of the ipsilateral limb. Conclusion: Significant differences in muscle strength and tissue structure between ipsilateral and contralateral limbs may reflect surgical and local pathophysiological effects. A trend toward reduced values for these parameters was also noted in limbs with BCRL, reinforcing the importance of future research to elucidate underlying mechanisms and guide more effective therapeutic strategies. Full article
(This article belongs to the Section Molecular and Translational Medicine)
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20 pages, 562 KiB  
Article
Effectiveness of a Post-Acute-Care Rehabilitation Program in Patients with Stroke: A Retrospective Cohort Study
by Yi-Pang Lo, Mei-Chen Wang, Yao-Hsiang Chen, Shang-Lin Chiang and Chia-Huei Lin
Life 2025, 15(8), 1216; https://doi.org/10.3390/life15081216 - 1 Aug 2025
Viewed by 568
Abstract
Early rehabilitation is essential for restoring functional recovery in patients with stroke, particularly during the early phase of post-acute care (PAC), or the subacute stage. We aimed to evaluate the effectiveness of a 7-week PAC rehabilitation program in improving muscle strength, physical performance, [...] Read more.
Early rehabilitation is essential for restoring functional recovery in patients with stroke, particularly during the early phase of post-acute care (PAC), or the subacute stage. We aimed to evaluate the effectiveness of a 7-week PAC rehabilitation program in improving muscle strength, physical performance, and functional recovery. A total of 219 inpatients with stroke in the subacute stage were initially recruited from the PAC ward of a regional teaching hospital in Northern Taiwan, with 79 eligible patients—within 1 month of an acute stroke—included in the analysis. The program was delivered 5 days per week, with 3–4 sessions daily (20–30 min each, up to 120 min daily), comprising physical, occupational, and speech–language therapies. Sociodemographic data, muscle strength, physical performance (Berg Balance Scale [BBS], gait speed, and 6-minute walk test [6MWT]), and functional recovery (modified Rankin Scale [mRS], Barthel Index [BI], Instrumental Activities of Daily Living [IADL], and Fugl–Meyer assessment: sensory and upper extremity) were collected at baseline, 3 weeks, and 7 weeks. Generalized estimating equations analyzed program effectiveness. Among the 56 patients (70.9%) who completed the program, significant improvements were observed in the muscle strength of both the affected upper (B = 0.93, p < 0.001) and lower limbs (B = 0.88, p < 0.001), as well as in their corresponding unaffected limbs; in physical performance, including balance (BBS score: B = 9.70, p = 0.003) and gait speed (B = 0.23, p = 0.024); and in functional recovery, including BI (B = 19.5, p < 0.001), IADL (B = 1.48, p < 0.001), and mRS (B = −0.13, p = 0.028). These findings highlight the 7-week PAC rehabilitation program as an effective strategy during the critical recovery phase for patients with stroke. Full article
(This article belongs to the Special Issue Advances in the Rehabilitation of Stroke)
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19 pages, 1517 KiB  
Article
Continuous Estimation of sEMG-Based Upper-Limb Joint Angles in the Time–Frequency Domain Using a Scale Temporal–Channel Cross-Encoder
by Xu Han, Haodong Chen, Xinyu Cheng and Ping Zhao
Actuators 2025, 14(8), 378; https://doi.org/10.3390/act14080378 - 31 Jul 2025
Viewed by 146
Abstract
Surface electromyographic (sEMG) signal-driven joint-angle estimation plays a critical role in intelligent rehabilitation systems, as its accuracy directly affects both control performance and rehabilitation efficacy. This study proposes a continuous elbow joint angle estimation method based on time–frequency domain analysis. Raw sEMG signals [...] Read more.
Surface electromyographic (sEMG) signal-driven joint-angle estimation plays a critical role in intelligent rehabilitation systems, as its accuracy directly affects both control performance and rehabilitation efficacy. This study proposes a continuous elbow joint angle estimation method based on time–frequency domain analysis. Raw sEMG signals were processed using the Short-Time Fourier Transform (STFT) to extract time–frequency features. A Scale Temporal–Channel Cross-Encoder (STCCE) network was developed, integrating temporal and channel attention mechanisms to enhance feature representation and establish the mapping from sEMG signals to elbow joint angles. The model was trained and evaluated on a dataset comprising approximately 103,000 samples collected from seven subjects. In the single-subject test set, the proposed STCCE model achieved an average Mean Absolute Error (MAE) of 2.96±0.24, Root Mean Square Error (RMSE) of 4.41±0.45, Coefficient of Determination (R2) of 0.9924±0.0020, and Correlation Coefficient (CC) of 0.9963±0.0010. It achieved a MAE of 3.30, RMSE of 4.75, R2 of 0.9915, and CC of 0.9962 on the multi-subject test set, and an average MAE of 15.53±1.80, RMSE of 21.72±2.85, R2 of 0.8141±0.0540, and CC of 0.9100±0.0306 on the inter-subject test set. These results demonstrated that the STCCE model enabled accurate joint-angle estimation in the time–frequency domain, contributing to a better motion intent perception for upper-limb rehabilitation. Full article
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17 pages, 876 KiB  
Article
Feasibility and Perceptions of Telerehabilitation Using Serious Games for Children with Disabilities in War-Affected Ukraine
by Anna Kushnir, Oleh Kachmar and Bruno Bonnechère
Appl. Sci. 2025, 15(15), 8526; https://doi.org/10.3390/app15158526 - 31 Jul 2025
Viewed by 148
Abstract
This study aimed to evaluate the feasibility of using serious games for the (tele)rehabilitation of children with disabilities affected by the Ukrainian war. Additionally, it provides requirements for technologies that can be used in war-affected areas. Structured interviews and Likert scale assessments were [...] Read more.
This study aimed to evaluate the feasibility of using serious games for the (tele)rehabilitation of children with disabilities affected by the Ukrainian war. Additionally, it provides requirements for technologies that can be used in war-affected areas. Structured interviews and Likert scale assessments were conducted on-site and remotely with patients of the tertiary care facility in Ukraine. All participants used the telerehabilitation platform for motor and cognitive training. Nine serious games were employed, involving trunk tilts, upper limb movements, and head control. By mid-September 2023, 186 positive user experiences were evident, with 89% expressing interest in continued engagement. The platform’s accessibility, affordability, and therapeutic benefits were highlighted. The recommendations from user feedback informed potential enhancements, showcasing the platform’s potential to provide uninterrupted rehabilitation care amid conflict-related challenges. This study suggests that serious games solutions that suit the sociopolitical and economic context offer a promising solution to rehabilitation challenges in conflict zones. The positive user experiences towards using the platform with serious games indicate its potential in emergency healthcare provision. The findings emphasize the role of technology, particularly serious gaming, in mitigating the impact of armed conflicts on children’s well-being, thereby contributing valuable insights to healthcare strategies in conflict-affected regions. Requirements for technologies tailored to the context of challenging settings were defined. Full article
(This article belongs to the Special Issue Novel Approaches of Physical Therapy-Based Rehabilitation)
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19 pages, 1913 KiB  
Systematic Review
Innovative but Difficult to Replicate: A Systematic Review of the Reporting Quality of Robotic and Conventional Upper-Limb Interventions in Stroke Rehabilitation Randomized Controlled Trials Using the TIDieR-Rehab Checklist
by Emeline Gomes, Gemma Alder, Kate Boardsworth, Kate L. Anderson, Sharon Olsen and Nada Signal
Appl. Sci. 2025, 15(15), 8487; https://doi.org/10.3390/app15158487 - 31 Jul 2025
Viewed by 261
Abstract
Background: Upper-limb impairment is a major cause of post-stroke disability, limiting participation in meaningful activities. Robotic rehabilitation may address this by delivering high-dosage, task-oriented training while reducing clinician workload. However, limited clinical translation of robotic interventions may be partly due to poor reporting [...] Read more.
Background: Upper-limb impairment is a major cause of post-stroke disability, limiting participation in meaningful activities. Robotic rehabilitation may address this by delivering high-dosage, task-oriented training while reducing clinician workload. However, limited clinical translation of robotic interventions may be partly due to poor reporting in the literature. This systematic review evaluated the intervention-reporting quality (completeness and consistency) of randomized controlled trials (RCTs) comparing robotic and conventional upper-limb stroke rehabilitation. Methods: Four databases were searched for RCTs investigating robotic upper-limb interventions compared with dose-matched conventional interventions for people with stroke. Intervention reporting was assessed using the TIDieR-Rehab checklist. Trained reviewers independently extracted and evaluated data, resolving discrepancies through consensus. Completeness and consistency were analyzed descriptively. Results: Among 25 RCTs, the overall reporting completeness was low (43%). Robotic interventions were better described (50%) than conventional interventions (36%). While timing and total dose were commonly reported, critical details on provider expertise, active dose, progressive challenge, personalization, and harms were often omitted. Reporting consistency was moderate (68%), with key information dispersed across article sections. Conclusions: Inadequate reporting limits the transparency, replication, and implementation of robotic upper-limb interventions. Adopting structured reporting frameworks like TIDieR-Rehab is essential for advancing the field. Full article
(This article belongs to the Special Issue Current Advances in Rehabilitation Technology)
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18 pages, 4452 KiB  
Article
Upper Limb Joint Angle Estimation Using a Reduced Number of IMU Sensors and Recurrent Neural Networks
by Kevin Niño-Tejada, Laura Saldaña-Aristizábal, Jhonathan L. Rivas-Caicedo and Juan F. Patarroyo-Montenegro
Electronics 2025, 14(15), 3039; https://doi.org/10.3390/electronics14153039 - 30 Jul 2025
Viewed by 298
Abstract
Accurate estimation of upper-limb joint angles is essential in biomechanics, rehabilitation, and wearable robotics. While inertial measurement units (IMUs) offer portability and flexibility, systems requiring multiple inertial sensors can be intrusive and complex to deploy. In contrast, optical motion capture (MoCap) systems provide [...] Read more.
Accurate estimation of upper-limb joint angles is essential in biomechanics, rehabilitation, and wearable robotics. While inertial measurement units (IMUs) offer portability and flexibility, systems requiring multiple inertial sensors can be intrusive and complex to deploy. In contrast, optical motion capture (MoCap) systems provide precise tracking but are constrained to controlled laboratory environments. This study presents a deep learning-based approach for estimating shoulder and elbow joint angles using only three IMU sensors positioned on the chest and both wrists, validated against reference angles obtained from a MoCap system. The input data includes Euler angles, accelerometer, and gyroscope data, synchronized and segmented into sliding windows. Two recurrent neural network architectures, Convolutional Neural Network with Long-short Term Memory (CNN-LSTM) and Bidirectional LSTM (BLSTM), were trained and evaluated using identical conditions. The CNN component enabled the LSTM to extract spatial features that enhance sequential pattern learning, improving angle reconstruction. Both models achieved accurate estimation performance: CNN-LSTM yielded lower Mean Absolute Error (MAE) in smooth trajectories, while BLSTM provided smoother predictions but underestimated some peak movements, especially in the primary axes of rotation. These findings support the development of scalable, deep learning-based wearable systems and contribute to future applications in clinical assessment, sports performance analysis, and human motion research. Full article
(This article belongs to the Special Issue Wearable Sensors for Human Position, Attitude and Motion Tracking)
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20 pages, 1125 KiB  
Review
Brain-Computer Interfaces for Stroke Motor Rehabilitation
by Alessandro Tonin, Marianna Semprini, Pawel Kiper and Dante Mantini
Bioengineering 2025, 12(8), 820; https://doi.org/10.3390/bioengineering12080820 - 30 Jul 2025
Viewed by 483
Abstract
Brain–computer interface (BCI) technology holds promise for improving motor rehabilitation in stroke patients. This review explores the immediate and long-term effects of BCI training, shedding light on the potential benefits and challenges. Clinical studies have demonstrated that BCIs yield significant immediate improvements in [...] Read more.
Brain–computer interface (BCI) technology holds promise for improving motor rehabilitation in stroke patients. This review explores the immediate and long-term effects of BCI training, shedding light on the potential benefits and challenges. Clinical studies have demonstrated that BCIs yield significant immediate improvements in motor functions following stroke. Patients can engage in BCI training safely, making it a viable option for rehabilitation. Evidence from single-group studies consistently supports the effectiveness of BCIs in enhancing patients’ performance. Despite these promising findings, the evidence regarding long-term effects remains less robust. Further studies are needed to determine whether BCI-induced changes are permanent or only last for short durations. While evaluating the outcomes of BCI, one must consider that different BCI training protocols may influence functional recovery. The characteristics of some of the paradigms that we discuss are motor imagery-based BCIs, movement-attempt-based BCIs, and brain-rhythm-based BCIs. Finally, we examine studies suggesting that integrating BCIs with other devices, such as those used for functional electrical stimulation, has the potential to enhance recovery outcomes. We conclude that, while BCIs offer immediate benefits for stroke rehabilitation, addressing long-term effects and optimizing clinical implementation remain critical areas for further investigation. Full article
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14 pages, 513 KiB  
Article
Tailoring Treatment in Complex Regional Pain Syndrome: A Comparative Study of Therapeutic Approaches in Complex Rehabilitation
by Iana Andreieva, Beata Tarnacka, Adam Zalewski and Justyna Wiśniowska
Pharmaceuticals 2025, 18(8), 1114; https://doi.org/10.3390/ph18081114 - 25 Jul 2025
Viewed by 274
Abstract
Complex regional pain syndrome (CRPS) is a disabling pain condition, which is distinct from other pain syndromes by the presence of autonomic dysfunction and regional inflammatory changes. Objectives: To explore the impact of pharmacological treatment strategies, specifically scheduled, on-demand dosing regimens versus lack [...] Read more.
Complex regional pain syndrome (CRPS) is a disabling pain condition, which is distinct from other pain syndromes by the presence of autonomic dysfunction and regional inflammatory changes. Objectives: To explore the impact of pharmacological treatment strategies, specifically scheduled, on-demand dosing regimens versus lack of medical treatment, on pain-related and functional outcomes in rehabilitation for individuals with CRPS. Methods: A total of 32 participants with CRPS were assigned to three treatment groups depending on analgesic treatment during the course of complex rehabilitation. Pre- and post-rehabilitation assessments were conducted using validated measures, including the Numerical Rating Scale (NRS) for pain, the Short-Form McGill Pain Questionnaire (SF-MPQ), PainDETECT, the Disabilities of the Arm, Shoulder, and Hand (DASH), and the Lower Extremity Functional Scale (LEFS). Results: Significant improvements in pain and upper limb function (DASH scores) were observed across all groups (p < 0.05). No statistically significant changes were found in lower limb function (LEFS). Between-group comparisons revealed significant differences in post-treatment pain scores (SFMPQ-B), particularly between groups with a constant treatment regimen and those without treatment. Conclusions: There were no statistically significant changes compared to different treatment regimen groups. The constant treatment group showed slightly better average improvements in pain and disability compared to other groups. Statistically significant improvements in all CRPS patients were observed in pain-related and functional measures. Full article
(This article belongs to the Special Issue Pharmacotherapy for Neuropathic Pain)
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23 pages, 2407 KiB  
Article
Replication of Sensor-Based Categorization of Upper-Limb Performance in Daily Life in People Post Stroke and Generalizability to Other Populations
by Chelsea E. Macpherson, Marghuretta D. Bland, Christine Gordon, Allison E. Miller, Caitlin Newman, Carey L. Holleran, Christopher J. Dy, Lindsay Peterson, Keith R. Lohse and Catherine E. Lang
Sensors 2025, 25(15), 4618; https://doi.org/10.3390/s25154618 - 25 Jul 2025
Viewed by 212
Abstract
Background: Wearable movement sensors can measure upper limb (UL) activity, but single variables may not capture the full picture. This study aimed to replicate prior work identifying five multivariate categories of UL activity performance in people with stroke and controls and expand those [...] Read more.
Background: Wearable movement sensors can measure upper limb (UL) activity, but single variables may not capture the full picture. This study aimed to replicate prior work identifying five multivariate categories of UL activity performance in people with stroke and controls and expand those findings to other UL conditions. Methods: Demographic, self-report, and wearable sensor-based UL activity performance variables were collected from 324 participants (stroke n = 49, multiple sclerosis n = 19, distal UL fracture n = 40, proximal UL pain n = 55, post-breast cancer n = 23, control n = 138). Principal component (PC) analyses (12, 9, 7, or 5 accelerometry input variables) were followed by cluster analyses and numerous assessments of model fit across multiple subsets of the total sample. Results: Two PCs explained 70–90% variance: PC1 (overall UL activity performance) and PC2 (preferred-limb use). A five-variable, five-cluster model was optimal across samples. In comparison to clusters, two PCs and individual accelerometry variables showed higher convergent validity with self-report outcomes of UL activity performance and disability. Conclusions: A five-variable, five-cluster model was replicable and generalizable. Convergent validity data suggest that UL activity performance in daily life may be better conceptualized on a continuum, rather than categorically. These findings highlight a unified, data-driven approach to tracking functional changes across UL conditions and severity of functional deficits. Full article
(This article belongs to the Special Issue Sensor-Based Human Activity Recognition)
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24 pages, 4249 KiB  
Article
Developing a Serious Video Game to Engage the Upper Limb Post-Stroke Rehabilitation
by Jaime A. Silva, Manuel F. Silva, Hélder P. Oliveira and Cláudia D. Rocha
Appl. Sci. 2025, 15(15), 8240; https://doi.org/10.3390/app15158240 - 24 Jul 2025
Viewed by 302
Abstract
Stroke often leads to severe motor impairment, especially in the upper limbs, greatly reducing a patient’s ability to perform daily tasks. Effective rehabilitation is essential to restore function and improve quality of life. Traditional therapies, while useful, may lack engagement, leading to low [...] Read more.
Stroke often leads to severe motor impairment, especially in the upper limbs, greatly reducing a patient’s ability to perform daily tasks. Effective rehabilitation is essential to restore function and improve quality of life. Traditional therapies, while useful, may lack engagement, leading to low motivation and poor adherence. Gamification—using game-like elements in non-game contexts—offers a promising way to make rehabilitation more engaging. The authors explore a gamified rehabilitation system designed in Unity 3D using a Kinect V2 camera. The game includes key features such as adjustable difficulty, real-time and predominantly positive feedback, user friendliness, and data tracking for progress. The evaluations were conducted with 18 healthy participants, most of whom had prior virtual reality experience. About 77% found the application highly motivating. While the gameplay was well received, the visual design was noted as lacking engagement. Importantly, all users agreed that the game offers a broad range of difficulty levels, making it accessible to various users. The results suggest that the system has strong potential to improve rehabilitation outcomes and encourage long-term use through enhanced motivation and interactivity. Full article
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12 pages, 459 KiB  
Article
Effects of Air Splints on Sensorimotor Disturbances of the Affected Upper Extremity and Trunk Control in Adult Post-Stroke Patients
by Ana Isabel Useros-Olmo, Roberto Cano-de-la-Cuerda, Jesús Rodríguez-Herranz, Alfonso Gil-Martínez and Alicia Hernando-Rosado
J. Clin. Med. 2025, 14(15), 5185; https://doi.org/10.3390/jcm14155185 - 22 Jul 2025
Viewed by 201
Abstract
Background: The present study aimed to determine whether the protocolized use of pneumatic splints within neurodevelopmental therapeutic approaches produces a positive effect on sensorimotor impairments of the hemiplegic upper extremity in patients. Methods: A randomized clinical single-blind trial was conducted. Stroke patients were [...] Read more.
Background: The present study aimed to determine whether the protocolized use of pneumatic splints within neurodevelopmental therapeutic approaches produces a positive effect on sensorimotor impairments of the hemiplegic upper extremity in patients. Methods: A randomized clinical single-blind trial was conducted. Stroke patients were recruited and randomized into an experimental group, which completed a treatment protocol of splinting plus physiotherapy for 45 min per session, two sessions per week for four weeks; or a control group, which received the same type of conventional physiotherapy treatment for the same period of time. The patients were evaluated by Fugl-Meyer Assessment of the Upper Extremity (FMA-UE) and the Trunk Control Scale. Secondary variables were Mini-BEStest, the modified Ashworth scale for ankle flexors, and computerized measurements of upper limb functional parameters performed by Armeo Spring® robotic systems and Amadeo®. All variables were measured pre- and post-treatment. Results: Twenty stroke patients with subacute and chronic stroke completed the protocol. Mann–Whitney U tests showed statistically significant differences between groups for the FM sensation variable (Z = −2.19; p = 0.03). The rest of the variables studied in the comparison between the two study groups did not present statistically significant differences (p > 0.05). Conclusions: The use of air splints in combination with physiotherapy treatment produced improvements in exteroceptive and proprioceptive sensitivity in post-stroke adult patients in the subacute and chronic phases. Full article
(This article belongs to the Section Clinical Rehabilitation)
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17 pages, 1788 KiB  
Article
Morphological and Functional Asymmetry Among Competitive Female Fencing Athletes
by Wiktoria Bany, Monika Nyrć and Monika Lopuszanska-Dawid
Appl. Sci. 2025, 15(14), 8020; https://doi.org/10.3390/app15148020 - 18 Jul 2025
Viewed by 285
Abstract
Maintaining body symmetry in sports characterized by high lateralization is crucial for optimizing long-term athletic performance and mitigating injury risk. This study aimed to evaluate the extent of morphological asymmetry in anthropometric features among elite professional fencers. Additionally, the presence of functional asymmetry [...] Read more.
Maintaining body symmetry in sports characterized by high lateralization is crucial for optimizing long-term athletic performance and mitigating injury risk. This study aimed to evaluate the extent of morphological asymmetry in anthropometric features among elite professional fencers. Additionally, the presence of functional asymmetry and its associations with morphological asymmetry were assessed. Thirty-two Polish adult female fencers, aged 18–33 yrs, were examined. Data collection involved a questionnaire survey, anthropometric measurements, calculation of anthropological indices, and assessment of functional asymmetry. For the 24 bilateral anthropometric features, small differences were found in seven characteristics: foot length, subscapular skinfold thickness, upper arm circumference, minimum and maximum forearm circumference, upper limb length, and arm circumference in tension. Morphological asymmetry index did not exceed 5%. Left-sided lateralization of either the upper or lower limbs was associated with significantly high asymmetry, specifically indicating larger minimum forearm circumferences in the right limb. Continuous, individualized monitoring of morphological asymmetry and its direction in athletes is essential, demanding concurrent consideration of functional lateralization. This ongoing assessment establishes a critical baseline for evaluating training adaptations, reducing injury susceptibility, and optimizing rehabilitation strategies. Deeper investigation of symmetry within non-dominant limbs is warranted to enhance our understanding. Full article
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15 pages, 2173 KiB  
Review
Optimal Sites for Upper Extremity Amputation: Comparison Between Surgeons and Prosthetists
by Brandon Apagüeño, Sara E. Munkwitz, Nicholas V. Mata, Christopher Alessia, Vasudev Vivekanand Nayak, Paulo G. Coelho and Natalia Fullerton
Bioengineering 2025, 12(7), 765; https://doi.org/10.3390/bioengineering12070765 - 15 Jul 2025
Viewed by 363
Abstract
Upper extremity amputations significantly impact an individual’s physical capabilities, psychosocial well-being, and overall quality of life. The level at which an amputation is performed influences residual limb function, prosthetic compatibility, and long-term patient satisfaction. While surgical guidelines traditionally emphasize maximal limb preservation, prosthetists [...] Read more.
Upper extremity amputations significantly impact an individual’s physical capabilities, psychosocial well-being, and overall quality of life. The level at which an amputation is performed influences residual limb function, prosthetic compatibility, and long-term patient satisfaction. While surgical guidelines traditionally emphasize maximal limb preservation, prosthetists often advocate for amputation sites that optimize prosthetic fit and function, highlighting the need for a collaborative approach. This review examines the discrepancies between surgical and prosthetic recommendations for optimal amputation levels, from digit amputations to shoulder disarticulations, and explores their implications for prosthetic design, functionality, and patient outcomes. Various prosthetic options, including passive functional, body-powered, myoelectric, and hybrid devices, offer distinct advantages and limitations based on the level of amputation. Prosthetists emphasize the importance of residual limb length, not only for mechanical efficiency but also for achieving symmetry with the contralateral limb, minimizing discomfort, and enhancing control. Additionally, emerging technologies such as targeted muscle reinnervation (TMR) and advanced myoelectric prostheses are reshaping rehabilitation strategies, further underscoring the need for precise amputation planning. By integrating insights from both surgical and prosthetic perspectives, this review highlights the necessity of a multidisciplinary approach involving surgeons, prosthetists, rehabilitation specialists, and patients in the decision-making process. A greater emphasis on preoperative planning and interprofessional collaboration can improve prosthetic outcomes, reduce device rejection rates, and ultimately enhance the functional independence and well-being of individuals with upper extremity amputations. Full article
(This article belongs to the Section Biomedical Engineering and Biomaterials)
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