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19 pages, 555 KB  
Article
Experiential Attractiveness, Self-Concept Connection, and Attitude Toward the Museum as Drivers of Visitor Experience and Location Loyalty in University Museums
by Héctor Hugo Pérez-Villarreal, Pedro Arturo Flores-Gómez, María Pilar Martínez-Ruiz and Tere Itzel Alva-Juárez
Tour. Hosp. 2026, 7(1), 7; https://doi.org/10.3390/tourhosp7010007 (registering DOI) - 30 Dec 2025
Abstract
Museums contribute significantly to the cultural and economic development of destinations, yet university museums remain underexplored, especially in developing economies. This study examines how experiential attractiveness (EA), attitude toward the museum (ATM), and self-concept connection (SCC) influence visitor experience (VE) and location loyalty [...] Read more.
Museums contribute significantly to the cultural and economic development of destinations, yet university museums remain underexplored, especially in developing economies. This study examines how experiential attractiveness (EA), attitude toward the museum (ATM), and self-concept connection (SCC) influence visitor experience (VE) and location loyalty (LL). Using data from 1400 visitors to university museums in Puebla, Mexico, Partial Least Squares Structural Equation Modeling (PLS-SEM) was applied to test the proposed relationships. All hypotheses were supported, with the strongest effects observed from EA to SCC and from SCC to VE, indicating that attractive and engaging experiences strengthen visitors’ self-connection and lead to greater satisfaction during the overall museum visit. The validated model demonstrates consistent relationships among constructs and contributes to understanding how attractiveness and self-connection shape behavioral intentions in the university museum context. These findings highlight the importance of experiential marketing and emotional engagement strategies, while future research should explore additional attitudinal and technological factors that enhance visitor loyalty. Full article
(This article belongs to the Special Issue Authentic Tourist Experiences: The Value of Intangible Heritage)
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27 pages, 1573 KB  
Article
A Multi-Dimensional Intelligence Framework to Explain Sustainable Employee Productivity
by Yuliia Shyron, Liana Chernobay, Dmytro Zherlitsyn, Oleksandr Dluhopolskyi, Sylwester Bogacki and Natalia Horbal
Sustainability 2026, 18(1), 368; https://doi.org/10.3390/su18010368 (registering DOI) - 30 Dec 2025
Abstract
In the context of sustainable development and the growing emphasis on decent work and productivity, understanding the human factors that shape employee performance has become a central concern for organizations and policymakers. While intelligence has long been linked to work outcomes, existing research [...] Read more.
In the context of sustainable development and the growing emphasis on decent work and productivity, understanding the human factors that shape employee performance has become a central concern for organizations and policymakers. While intelligence has long been linked to work outcomes, existing research remains fragmented and predominantly focused on single dimensions, offering limited insight into how different forms of intelligence interact across employees’ career life cycles. Addressing this gap, the present study advances a multi-dimensional perspective on intelligence and examines its relevance for sustainable employee productivity, thereby contributing to the human resource management literature and to the achievement of Sustainable Development Goal 8 (Decent Work and Economic Growth). The study assesses the impact of five types of intelligence (cognitive—IQ, emotional—EQ, physical—PQ, vitality—VQ, and social—SQ) on employee productivity across distinct career life cycle stages. The research was conducted in two phases: (1) measurement of intelligence dimensions and employee productivity using standardized psychometric instruments, including MSCEIT V2.0, the Guilford–O’Sullivan test, the Eysenck test, the Chekhov vitality method, and biological age indicators; (2) statistical analysis of the relationships between intelligence, productivity, and career stages using open-source Python tools. Empirical data were collected from enterprises in the Ukrainian construction industry. The findings demonstrate that the influence of intelligence on productivity varies across career stages. Emotional intelligence emerges as a consistently significant factor throughout the employee life cycle, while other intelligence dimensions exhibit stage-specific effects. These results confirm the dynamic and non-uniform nature of intelligence–productivity relationships. The study provides practical insights for sustainable human resource management by highlighting the need for stage-sensitive development strategies that align intelligence profiles with career phases. Implementing such targeted approaches can enhance employee productivity, organizational effectiveness, and long-term economic sustainability, thereby supporting progress toward SDG 8. Full article
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17 pages, 3084 KB  
Article
Neuromodulatory Effects of Arecoline on Anxiety-like Behavior in Mice Exposed to Chronic Unpredictable Mild Stress
by Xiangfei Zhang, Danyang Wang, Jingwen Cui, Bei Fan, Fengzhong Wang and Cong Lu
Int. J. Mol. Sci. 2026, 27(1), 371; https://doi.org/10.3390/ijms27010371 (registering DOI) - 29 Dec 2025
Abstract
Chronic stress disrupts neuroendocrine regulation, neurotransmitter balance, and neuronal redox homeostasis, thereby contributing to the development of anxiety-related neuropathology. Arecoline, the predominant alkaloid of Areca catechu L., displays diverse neuropharmacological properties, yet its role in stress-induced emotional dysfunction has not been fully elucidated. [...] Read more.
Chronic stress disrupts neuroendocrine regulation, neurotransmitter balance, and neuronal redox homeostasis, thereby contributing to the development of anxiety-related neuropathology. Arecoline, the predominant alkaloid of Areca catechu L., displays diverse neuropharmacological properties, yet its role in stress-induced emotional dysfunction has not been fully elucidated. This study examined the anxiolytic-like and neuroprotective effects of arecoline in mice exposed to chronic unpredictable mild stress (CUMS). Arecoline administration markedly improved behavioral outcomes, reflected by increased central exploration in the open-field test, prolonged time in the light compartment, and enhanced open-arm activity in the elevated plus maze. These behavioral benefits were accompanied by normalization of serum corticosterone levels, restoration of hippocampal neurotransmitters, reinforcement of antioxidant enzyme activities, and attenuation of pro-inflammatory cytokines. At the molecular level, arecoline elevated brain-derived neurotrophic factor (BDNF), tropomyosin receptor kinase B (TrkB), cAMP response element-binding protein (CREB), N-methyl-D-aspartate receptor (NMDAR), and Ca2+/calmodulin-dependent protein kinase II (CaMKII), indicating enhanced synaptic plasticity, while concurrently diminishing oxidative and inflammatory stress. Collectively, the findings suggest that arecoline exerts multifaceted neuroprotective actions under chronic stress by coordinating neuroendocrine modulation, neurotransmitter homeostasis, antioxidant defenses, and synaptic plasticity. This study provides new mechanistic evidence supporting the potential relevance of arecoline as a functional neuroactive compound for managing stress-induced anxiety disorders. Full article
(This article belongs to the Special Issue Role of Natural Compounds in Human Health and Disease)
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23 pages, 797 KB  
Article
Drivers of People’s Connectedness with Nature in Urban Areas: Community Gardening Acceptance in a Densely Populated City
by Rahim Maleknia and Aureliu-Florin Hălălișan
Urban Sci. 2026, 10(1), 15; https://doi.org/10.3390/urbansci10010015 (registering DOI) - 29 Dec 2025
Abstract
Community gardening has become an important urban sustainability initiative that integrates ecological restoration with social participation. However, little is known about the psychological and social mechanisms that drive citizens’ willingness to engage in such activities, particularly in densely populated cities with limited green [...] Read more.
Community gardening has become an important urban sustainability initiative that integrates ecological restoration with social participation. However, little is known about the psychological and social mechanisms that drive citizens’ willingness to engage in such activities, particularly in densely populated cities with limited green space. This study develops and empirically tests an integrative behavioral model combining environmental psychology, social cognitive theory, and environmental identity theory to explain citizens’ participation in community gardening in Tehran, Iran. Using survey data from 416 residents and analyzing results through structural equation modeling, the study evaluates the effects of six key predictors, including childhood nature experience, connectedness to nature, self-efficacy, outcome expectancy, psychological restoration, and collective environmental responsibility, on willingness to participate. The model explained 54% of the variance in participation, indicating high explanatory power. Five predictors significantly influenced willingness to participate: childhood nature experience, connectedness to nature, outcome expectancy, psychological restoration, and collective environmental responsibility, while self-efficacy was not significant. The findings reveal that engagement in community gardening is shaped more by emotional, restorative, and moral motivations than by perceived capability alone. Theoretically, this research advances understanding of pro-environmental participation by integrating memory-based, affective, and normative dimensions of behavior. Practically, it provides actionable insights for urban planners and policymakers to design inclusive, emotionally restorative, and collectively managed green initiatives that strengthen citizen participation and enhance urban resilience. Full article
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22 pages, 808 KB  
Article
Understanding Athlete Emotions: A Psychometric Approach to the AEQ-S in Sports
by María-Jesús Lirola, Rubén Trigueros, José Manuel Aguilar Parra and Clemente Franco
Brain Sci. 2026, 16(1), 46; https://doi.org/10.3390/brainsci16010046 (registering DOI) - 29 Dec 2025
Abstract
Introduction: This study focuses on the adaptation and validation of the Achievement Emotions Questionnaire-Short (AEQ-S) to the Spanish sports context. Emotions play a crucial role in athletes’ decision making, making it essential to have reliable assessment tools tailored to this field. Method: The [...] Read more.
Introduction: This study focuses on the adaptation and validation of the Achievement Emotions Questionnaire-Short (AEQ-S) to the Spanish sports context. Emotions play a crucial role in athletes’ decision making, making it essential to have reliable assessment tools tailored to this field. Method: The AEQ-S was administered to 998 professional athletes (mean age: 26.83 years). The adaptation followed the Hambleton method and involved the support of sports psychologists. Exploratory (EFA) and confirmatory factor analyses (CFAs) were conducted, along with tests for reliability and criterion validity. Results: The analyses confirmed that the factor structure of the AEQ-S in sports aligns with the original version, identifying eight key emotions: enjoyment, hope, pride, anxiety, anger, shame, hopelessness, and boredom. Furthermore, positive emotions were positively associated with resilience, while negative emotions showed an inverse relationship. Conclusions: The adapted AEQ-S proved to be a valid and reliable tool for assessing emotions in athletes. Its applications extend to both research and professional practice in the sports domain. Full article
(This article belongs to the Special Issue Advances in Cognitive and Psychometric Evaluation)
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22 pages, 878 KB  
Article
Addressing Teacher Occupational Health in Challenging Times: The Role of a Positive Organizational Climate in Buffering Teachers’ Burnout
by Sofia Oliveira, Magda Sofia Roberto, Ana Margarida Veiga-Simão and Alexandra Marques-Pinto
Int. J. Environ. Res. Public Health 2026, 23(1), 42; https://doi.org/10.3390/ijerph23010042 - 28 Dec 2025
Viewed by 26
Abstract
Teacher occupational health is a critical issue worldwide that COVID-19 has worsened. While previous research has highlighted the impact of chronic work-related stress and limited personal resources on burnout, much of this research relies on cross-sectional data that do not capture how these [...] Read more.
Teacher occupational health is a critical issue worldwide that COVID-19 has worsened. While previous research has highlighted the impact of chronic work-related stress and limited personal resources on burnout, much of this research relies on cross-sectional data that do not capture how these effects develop over time. Additionally, the role of positive organizational factors remains underexplored. Our study examined burnout trajectories among 101 Portuguese elementary teachers (94.1% women, M = 46.03 years, 85.6% enrollment rate) over five data collection points spanning the 1st and 2nd COVID-19 waves (2019–2021) and investigated the impact of organizational climate on teacher burnout indicators. Main work-related stressors were identified through an open-ended question. Trajectories of occupational stress and burnout were analyzed using independent ANOVAs, and moderation analyses tested the relationship between organizational climate, occupational stress, and burnout indicators. Results showed a significant drop in perceived personal accomplishment during the first lockdown. Key stressors included greater job demands and more strained interpersonal relationships. Organizational climate significantly moderated the effect of work-related stress on emotional exhaustion, while having a positive main effect on personal accomplishment. This research contributes to a strengthened theoretical understanding of burnout as a dynamic, context-sensitive process, offering new empirical evidence, especially in underrepresented educational systems like Portugal. It emphasizes the importance of addressing contextual factors when working to reduce teacher burnout. Rethinking professional development and workplace relationships is essential for supporting teachers’ occupational health in today’s uncertain educational environments. Full article
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12 pages, 273 KB  
Article
Stimulant Treatment Gap in ADHD Patients with Heroin Use Disorder: Clinical and Behavioural Consequences
by Alessandro Pallucchini, Maurizio Varese, Irene Pergentini, Samuele Gemignani, Elisa Parapetto, Icro Maremmani and Angelo Giovanni Icro Maremmani
Int. J. Environ. Res. Public Health 2026, 23(1), 40; https://doi.org/10.3390/ijerph23010040 - 28 Dec 2025
Viewed by 30
Abstract
Background: Adults with attention-deficit/hyperactivity disorder (ADHD) often have comorbid substance use disorders (SUDs). In Italy, individuals with both ADHD and heroin use disorder (HUD) are usually treated in addiction services with opioid agonist therapy (OAT), but stimulant medications are rarely prescribed. This may [...] Read more.
Background: Adults with attention-deficit/hyperactivity disorder (ADHD) often have comorbid substance use disorders (SUDs). In Italy, individuals with both ADHD and heroin use disorder (HUD) are usually treated in addiction services with opioid agonist therapy (OAT), but stimulant medications are rarely prescribed. This may create a treatment gap for core ADHD symptoms. Aim: This study examined the clinical and behavioural profiles of ADHD patients with HUD who receive OAT but no stimulant treatment, compared to ADHD patients without opioid use disorder (ADHD/NoHUD) on standard pharmacotherapy. All participants were considered treatment responders in their respective services. Methods: Data were collected from two outpatient clinics and included 103 adult ADHD patients assessed using validated tools for symptom severity, emotional dysregulation, and global functioning. Differences between groups were analysed using univariate tests and logistic regression. Results: The ADHD+HUD group was significantly older and showed higher levels of emotional dysregulation, impulsivity, and current cocaine use. Despite clinical stability, these individuals presented a more severe psychopathological profile than their ADHD/NoHUD counterparts, who received stimulant-based treatment. Conclusions: Although limited by its cross-sectional nature and setting-related confounders, the study indicates that OAT alone may not be sufficient to manage neurodevelopmental symptoms in ADHD+HUD patients. Further research is necessary to assess the safety and efficacy of integrated stimulant-based treatments, ideally within dual disorder services combining psychiatric and addiction expertise. Full article
12 pages, 234 KB  
Article
Associations of ADHD and Borderline Personality Disorder with Suicidality in Adolescents: Additive and Interactive Effects
by Bartłomiej Sporniak, Przemysław Zakowicz and Monika Szewczuk-Bogusławska
J. Clin. Med. 2026, 15(1), 224; https://doi.org/10.3390/jcm15010224 - 27 Dec 2025
Viewed by 87
Abstract
Background/Objectives: Suicidal behaviors are a major clinical concern in adolescents, particularly among those with disorders marked by emotion dysregulation and impulsivity. Although attention-deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD) each heighten suicide risk, little is known about whether their occurrence confers [...] Read more.
Background/Objectives: Suicidal behaviors are a major clinical concern in adolescents, particularly among those with disorders marked by emotion dysregulation and impulsivity. Although attention-deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD) each heighten suicide risk, little is known about whether their occurrence confers additive or interactive effects in youth. This study examined whether ADHD and BPD diagnoses show additive or interactive associations with the suicide risk in adolescents. Methods: In this cross-sectional observational clinical study, the sample included 108 Polish adolescents (66.7% female; aged 13–17 years) recruited from inpatient and outpatient psychiatric settings (Independent Public Healthcare Facility, Children and Youth Treatment Center in Zabór, the Youth Sociotherapy Center No. 2 in Wrocław, and the District Educational Center in Jerzmanice-Zdrój (Poland)). The data collection for our study was conducted between May 2024 and July 2025. Diagnoses and suicide risk were assessed using the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID 7.02). Associations of ADHD and BPD with suicide risk were tested using linear and logistic regression models while accounting for age, sex, the current depressive episode, and the use of psychiatric medications. Results: Unadjusted analyses revealed significant main, but not interactive, associations of BPD and ADHD with suicide risk. When covariates were included in the model, BPD remained strongly associated with suicidality severity and with the presence of any suicide risk (adjusted OR = 7.00, 95% CI [1.55–31.57]), whereas the association between ADHD and suicidality was attenuated and did not reach conventional levels of statistical significance (adjusted OR = 3.48, 95% CI [0.93–13.08]). No statistically detectable ADHD × BPD interaction was observed. Estimates for ADHD were directionally consistent across models but characterized by wide confidence intervals. Conclusions: Adolescents with BPD appear to be at particularly high risk of suicide and should receive focused assessment, safety planning, and early intervention as part of routine care. In contrast, suicidality among adolescents with ADHD appears to be influenced by co-occurring clinical conditions, and its independent association with suicide risk remains statistically uncertain after adjustment. Clinicians should therefore remain alert to suicidality in youth with ADHD, while paying particular attention to accompanying symptoms and comorbid diagnoses that may further increase risk. Full article
(This article belongs to the Section Mental Health)
12 pages, 1509 KB  
Article
The Effect of Sacubitril/Valsartan on Mood and Cognitive Function in Patients with Heart Failure with Reduced Ejection Fraction
by Fahad Al Kindi, Raya Al Maskari, Fatma Al Mahruqi, Adil Al Riyami, Zuhra Al Yarabi, Rasha Kaddoura, Mujahid Al Busaidi and Samir Al Adawi
Brain Sci. 2026, 16(1), 38; https://doi.org/10.3390/brainsci16010038 - 27 Dec 2025
Viewed by 114
Abstract
Background/Objectives: Heart failure with reduced ejection fraction (HFrEF) is associated with significant neuropsychological burden, including cognitive impairment and mood disturbances. While sacubitril/valsartan has demonstrated cardiovascular benefits, its effects on cognitive and emotional functioning remain underexplored, particularly in Middle Eastern populations. We aimed [...] Read more.
Background/Objectives: Heart failure with reduced ejection fraction (HFrEF) is associated with significant neuropsychological burden, including cognitive impairment and mood disturbances. While sacubitril/valsartan has demonstrated cardiovascular benefits, its effects on cognitive and emotional functioning remain underexplored, particularly in Middle Eastern populations. We aimed to evaluate the impact of sacubitril/valsartan on intellectual capacity, cognitive function and mood in patients with HFrEF using an idiographic study design. Methods: This study was conducted in adult patients with HFrEF selected to take sacubitril/valsartan to improve their clinical status. Participants were assessed at baseline and 3 months after treatment initiation using Al Khoudh Cognitive Test, PHQ-9 and Raven’s Progressive Colored Matrices. Results: Following three months of treatment, participants showed a statistically significant improvement in left ventricular ejection fraction (LVEF) (p = 0.043), depression severity (p = 0.025) and a non-significant trend toward improvement in abstract reasoning scores (p = 0.051). On the other hand, participants did not demonstrate significant improvements in the cognitive subdomains assessed by the Al Khoudh Test. Among these subdomains, the largest improvement was observed with verbal fluency (p = 0.057). Improvements in LVEF were not significantly associated with the changes in mood (p = 0.93), cognitive function (p = 0.34) or verbal fluency (p = 0.46). Conclusions: This study provides preliminary, hypothesis-generating evidence of potential short-term improvement in mood and reasoning scores in HFrEF patients treated with sacubitril/valsartan. Notably, these changes were not attributed to the observed improvements in cardiac function. These findings underscore the need for further investigation into the neurocognitive benefits of sacubitril/valsartan in larger and more diverse populations. Full article
(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
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17 pages, 428 KB  
Article
Psychological Resources, Stress, and Well-Being in Adolescence: An Integrative Structural Model
by Sándor Rózsa and Andrea Kövesdi
Children 2026, 13(1), 38; https://doi.org/10.3390/children13010038 - 26 Dec 2025
Viewed by 95
Abstract
Background/Objectives: Emotional and behavioral difficulties are common during adolescence and have lasting implications for well-being. Although several psychological resources—such as self-efficacy, mindfulness, and reflective functioning—have been individually linked to better adjustment, less is known about how these strengths jointly relate to perceived [...] Read more.
Background/Objectives: Emotional and behavioral difficulties are common during adolescence and have lasting implications for well-being. Although several psychological resources—such as self-efficacy, mindfulness, and reflective functioning—have been individually linked to better adjustment, less is known about how these strengths jointly relate to perceived stress, difficulties, and health-related quality of life (HRQoL). This study aimed to develop and test an integrative structural model capturing the interplay of these factors during early and mid-adolescence. Methods: A cross-sectional online survey was conducted among 395 adolescents (222 girls, 173 boys; aged 10–16 years) who completed self-report questionnaires assessing HRQoL (KIDSCREEN-10), emotional–behavioral difficulties (SDQ), perceived stress (PSS), self-efficacy (GSE), mindfulness (CAMM), and reflective functioning (RFQY-5). After descriptive analyses and correlation testing, the structural path model using observed variables examined how these variables were interrelated. Multi-group analyses assessed whether structural pathways were invariant across gender and age groups. Results: Mindfulness, self-efficacy, and reflective functioning were each indirectly associated with better HRQoL, mainly through lower perceived stress and fewer emotional–behavioral difficulties. Perceived stress showed a strong positive association with difficulties, and both constructs uniquely predicted lower HRQoL. The overall pattern of associations was fully consistent across age and broadly comparable across gender. Conclusions: The findings highlight the interconnected role of psychological resources, stress, and emotional–behavioral difficulties in adolescents’ well-being. However, the cross-sectional design, convenience sampling, reliance on self-report measures, and single-country sample limit the generalizability and causal interpretation of the results. The robustness of these pathways across age and their broad comparability across gender underscore their developmental relevance and suggest that programs aimed at strengthening socio-emotional competences may be meaningfully applied to support adolescents’ well-being already from early adolescence. Full article
(This article belongs to the Special Issue Children’s Behaviour and Social-Emotional Competence)
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23 pages, 1616 KB  
Article
Drivers of Revisit Intention in a Sacred Heritage Site: An Integrated Theory of Planned Behavior, Attribution Theory, and Elaboration Likelihood Model Approach at Mount Wutai
by Wenqi Liu, Jirawan Deeprasert and Songyu Jiang
Tour. Hosp. 2026, 7(1), 5; https://doi.org/10.3390/tourhosp7010005 - 26 Dec 2025
Viewed by 175
Abstract
As a representative case that embodies both the attributes of a Buddhist sacred site and those of a UNESCO World Heritage site, Mount Wutai provides a distinctive research setting for examining behavioral mechanisms in temple tourism. This study aims to construct an integrated [...] Read more.
As a representative case that embodies both the attributes of a Buddhist sacred site and those of a UNESCO World Heritage site, Mount Wutai provides a distinctive research setting for examining behavioral mechanisms in temple tourism. This study aims to construct an integrated model to systematically test the effects of enjoyment, memorability, attitude, subjective norm, and perceived behavioral control (PBC) on revisit intention (RI), while incorporating social media exposure as a moderating variable. Based on data collected through a two-wave on-site survey, this study analyzed 617 tourists in Mount Wutai and employed structural equation model to examine the relationships among the variables. The results indicate that all five psychological antecedents exert significant positive effects on revisit intention, among them, PBC demonstrating the most substantial impact. Further analysis reveals that social media exposure significantly moderates the relationships among enjoyment, memorability, attitude, subjective norm, and revisit intention, most notably in the “memorability–RI” relationship, whereas its moderating effect on the “PBC–RI” relationship is not significant. These findings not only enrich the theoretical framework by integrating emotional attribution, behavioral cognition, and digital media engagement but also provide practical implications for sacred tourism destinations, enabling them to enhance visitor loyalty through digital communication and experience optimization. Full article
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12 pages, 4899 KB  
Article
Analytical Modeling of Hybrid CNN-Transformer Dynamics for Emotion Classification
by Ergashevich Halimjon Khujamatov, Mirjamol Abdullaev and Sabina Umirzakova
Mathematics 2026, 14(1), 85; https://doi.org/10.3390/math14010085 - 25 Dec 2025
Viewed by 140
Abstract
Facial expression recognition (FER) is crucial for affective computing and human–computer interaction; however, it is still difficult to achieve under various conditions in the real world, such as lighting, occlusion, and pose. This work presents a lightweight hybrid network, SE-Hybrid + Face-ViT, which [...] Read more.
Facial expression recognition (FER) is crucial for affective computing and human–computer interaction; however, it is still difficult to achieve under various conditions in the real world, such as lighting, occlusion, and pose. This work presents a lightweight hybrid network, SE-Hybrid + Face-ViT, which merges convolutional and transformer architectures through multi-level feature fusion and adaptive channel attention. The network includes a convolutional stream to capture the fine-grained texture of the image and a retrained Face-ViT branch to provide the high-level semantic context. Squeeze-and-Excitation (SE) modules adjust the channel responses at different levels, thus allowing the network to focus on the emotion-salient cues and suppress the redundant features. The proposed architecture, trained and tested on the large-scale AffectNet benchmark, achieved 70.45% accuracy and 68.11% macro-F1, thereby outperforming the latest state-of-the-art models such as TBEM-Transformer, FT-CSAT, and HFE-Net by around 2–3%. Grad-CAM-based visualization of the model confirmed accurate attention to the most significant facial areas, resulting in better recognition of subtle expressions such as fear and contempt. The findings indicate that SE-Hybrid + Face-ViT is a computationally efficient yet highly discriminative FER strategy that successfully addresses the issue of how to preserve details while globally reasoning with contextual information locally. Full article
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14 pages, 639 KB  
Article
A Cross-Sectional Evaluation of Caregiver Burden in Schizophrenia Care: Findings from Western Saudi Arabia with Policy Implications for Preventive Mental Healthcare
by Ashokkumar Thirunavukkarasu and Ebtehal Mobarak Zawawi
Healthcare 2026, 14(1), 55; https://doi.org/10.3390/healthcare14010055 - 25 Dec 2025
Viewed by 146
Abstract
Background/Objectives: Research about the effects of schizophrenia, along with caregiver burden, exists extensively in Western countries. However, research on Middle Eastern societies, especially Saudi Arabia, is limited. We assessed the burden experienced by caregivers of individuals with schizophrenia and identified the associated [...] Read more.
Background/Objectives: Research about the effects of schizophrenia, along with caregiver burden, exists extensively in Western countries. However, research on Middle Eastern societies, especially Saudi Arabia, is limited. We assessed the burden experienced by caregivers of individuals with schizophrenia and identified the associated factors contributing to it. Methods: The current cross-sectional study was conducted in Jeddah, Western Saudi Arabia, from December 2024 to March 2025. We used a validated Arabic data collection tool comprising 22 items that assessed five domains of caregiver burden. The associations between background characteristics and individual domains were determined by the Mann–Whitney U test and the Kruskal–Wallis test. We applied binomial regression analysis to find the factors associated with caregiver burden. Results: Of the 330 participants studied, no burden was observed in 17.9%. The remaining had mild (25.8%), moderate (34.8%), and severe (21.5%) burdens. Among the domains, emotional strain showed the highest mean (11.52 ± 4.32), followed closely by time and social limitations (11.29 ± 5.07) and health and financial impacts (11.08 ± 5.08). The caregiver burden was significantly higher among the adult children caring for their parents (p = 0.034) and lower among the participants working in the government sector (p = 0.022). Conclusions: The findings suggest a policy-relevant support program that includes workplace flexibility and financial help to manage their overall caregiving load and improve their health. Future research should explore the effectiveness of support strategies tailored to caregivers in different sociocultural contexts to enhance both caregiver and patient outcomes. Full article
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14 pages, 2488 KB  
Article
Exploring Consequences of Predator Stress on Behaviors of Mice Lacking Trace Amine-Associated Receptor 5 (TAAR5)
by Vsevolod V. Nemets, Vladimir P. Grinevich, Evgeniia N. Petrunina, Evgeny A. Budygin and Raul R. Gainetdinov
Cells 2026, 15(1), 39; https://doi.org/10.3390/cells15010039 - 25 Dec 2025
Viewed by 120
Abstract
Recent studies indicated a connection between trace amine-associated receptor 5 (TAAR5) and emotional behaviors related to anxiety and depression; however, the neurobiological basis of this link is still unclear. Using mutant TAAR5 knockout (TAAR5-KO) mice, we explored the consequences of receptor deletion on [...] Read more.
Recent studies indicated a connection between trace amine-associated receptor 5 (TAAR5) and emotional behaviors related to anxiety and depression; however, the neurobiological basis of this link is still unclear. Using mutant TAAR5 knockout (TAAR5-KO) mice, we explored the consequences of receptor deletion on dopamine (DA) dynamics in the ventral striatum and stress-related behaviors. Voltammetric measurements of DA in the nucleus accumbens (NAc) coupled with electrical stimulation of the ventral tegmental area (VTA) revealed that mice lacking TAAR5 display a greater DA release, while its reuptake is not affected. Behaviorally, mutants were significantly less anxious in the elevated plus maze (EPM) and consumed more sucrose in comparison with wild-type (WT) controls. The new object recognition test (NOR) did not uncover a difference between these genotypes. During predator (rat) stress exposure, mutant and WT mice showed quite distinct responses versus the behavior observed in stressless conditions. Control animals demonstrated a substantial increase in “freezing” (a sign of passive coping), while “running” and “exploring” patterns (signs of active coping) were significantly extended in mice lacking TAAR5. Short-term consequences of stress were explored 24 h following the predator exposure. The absence of TAAR5 did not prevent or reduce stress-induced anxiety in the EPM. In fact, the level of anxiety in mutants reached that observed in control mice. Furthermore, activity in NOR was significantly decreased in mice lacking TAAR5 but not in WT animals. On the other hand, predator exposure resulted in impaired NOR in the WT control, whereas mutants’ performance was not altered. These findings indicate that TAAR5 deletion leads to significant DA imbalance, which might at least partly explain the better stress-coping strategy and other stress-induced behavioral consequences observed in mutant animals. Full article
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22 pages, 1329 KB  
Article
Anxiety-Related Modulation of Early Neural Responses to Task-Irrelevant Emotional Faces
by Eligiusz Wronka
Brain Sci. 2026, 16(1), 26; https://doi.org/10.3390/brainsci16010026 - 25 Dec 2025
Viewed by 191
Abstract
Objectives: The purpose of the study was to test the hypothesis that high anxiety is associated with biased processing of threat-related stimuli and that anxious individuals may be particularly sensitive to facial expressions of fear or anger. In addition, these effects may [...] Read more.
Objectives: The purpose of the study was to test the hypothesis that high anxiety is associated with biased processing of threat-related stimuli and that anxious individuals may be particularly sensitive to facial expressions of fear or anger. In addition, these effects may result from a specific pattern occurring in the early stages of visual information processing. Methods: Event-Related Potentials (ERPs) were recorded in response to task-irrelevant pictures of faces presented in either an upright or inverted position in two groups differing in trait anxiety, as assessed by scores on the Spielberger Trait Anxiety Inventory (STAI). Behavioural responses and ERP activity were also recorded in response to simple neutral visual stimuli presented during exposure to the facial stimuli, which served as probe-targets. Results: A typical Face Inversion Effect was observed, characterised by longer latencies and greater amplitudes of the early P1 and N170 ERP components. Differences between low- and high-anxious individuals emerged at parieto-occipital sites within the time window of the early P1 component. The later stage of face processing, indexed by the N170 component, was not affected by the level of trait anxiety. Conclusions: The results of this experiment indicate that anxiety level modulates the initial stages of information processing, as reflected in the P1 component. This may be associated with anxiety-related differences in the involuntary processing of face detection of emotional expression. Consequently, a greater attentional engagement appears to occur in highly anxious individuals, leading to delayed behavioural responses to concurrently presented neutral stimuli. Full article
(This article belongs to the Special Issue Advances in Face Perception and How Disorders Affect Face Perception)
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