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Keywords = surge arrester

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16 pages, 1810 KiB  
Article
Insulation Online Monitoring Method for Dry-Type Current Transformers Based on Virtual Voltage
by Junjie Zhang, Yu Peng, Xiaohui Hu, Zhipeng Li, Li Yan, Can Ding and Ruihua Zhao
Energies 2025, 18(13), 3499; https://doi.org/10.3390/en18133499 - 2 Jul 2025
Viewed by 290
Abstract
To improve the accuracy of insulation state online monitoring for capacitive dry-type current transformers (CTs) and to address the limitations of traditional methods relying on potential transformer (PT) voltage signals and reference devices, a virtual voltage-based online monitoring method is proposed. First, the [...] Read more.
To improve the accuracy of insulation state online monitoring for capacitive dry-type current transformers (CTs) and to address the limitations of traditional methods relying on potential transformer (PT) voltage signals and reference devices, a virtual voltage-based online monitoring method is proposed. First, the leakage current is collected through a core-type current transformer on the end-screen grounding line. Combined with group measurement data from surge arresters and dry-type CTs on the same busbar, phase constraints are established, and a least mean square (LMS) algorithm is utilized to iteratively train the virtual voltage reference phase. Subsequently, the resistive current and dielectric loss factor (tan δ) are calculated based on the virtual voltage reference phase to achieve online insulation state monitoring. Simulation results demonstrate that the proposed method can accurately obtain the virtual voltage reference phase and effectively identify the degradation trend of dry-type CTs. Field applications validate the feasibility of the method, with monitoring data fluctuations (±20 μA for the resistive current and ±0.002 for the dielectric loss) meeting engineering requirements. This method eliminates the need for PT signals and reference devices, thus providing a novel approach for the online insulation monitoring of dry-type CTs. Full article
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19 pages, 5909 KiB  
Article
Research on Overcurrent in Offshore MMC and Suppression Strategies Based on Field–Circuit Coupling Analysis
by Jun Zhang, Shuhong Wang, Youpeng Huangfu and Ruting Tang
Appl. Sci. 2025, 15(5), 2729; https://doi.org/10.3390/app15052729 - 4 Mar 2025
Viewed by 646
Abstract
Due to system failures and the limited overcurrent capability of semiconductor devices, overcurrent in modular multilevel converters (MMC) is a key factor affecting the safe and stable operation of offshore wind power MMC-HVDC (modular multilevel converter high-voltage direct current) transmission systems. This paper [...] Read more.
Due to system failures and the limited overcurrent capability of semiconductor devices, overcurrent in modular multilevel converters (MMC) is a key factor affecting the safe and stable operation of offshore wind power MMC-HVDC (modular multilevel converter high-voltage direct current) transmission systems. This paper proposes a field–circuit coupling analysis method for overcurrent research in MMC valve. The method integrates the electric field characteristics of valves with the analysis of MMC-HVDC systems. Firstly, the development process and influencing factors of overcurrent in valves in offshore wind power MMC-HVDC systems are analyzed. A field–circuit coupling model and an electric field calculation model for MMC valves are established. The electric field characteristics and stray parameters of MMC valves are analyzed synchronously and the result are incorporated into the field–circuit coupling model. The nonlinear transient parameters of surge arresters are calculated, and the results are incorporated into the field–circuit coupling model. Finally, a reasonable overcurrent suppression strategy for offshore MMC-HVDC valves is proposed based on the proposed method. The effectiveness and practicality of the field–circuit coupling overcurrent analysis method are verified through comprehensive case studies conducted on the ±500kV offshore MMC-HVDC valve overcurrent calculation and suppression. Full article
(This article belongs to the Section Marine Science and Engineering)
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16 pages, 5952 KiB  
Article
Hardware Design for Cascade-Structure, Dual-Stage, Current-Limiting, Solid-State DC Circuit Breaker
by Can Ding, Yinbo Ji and Zhao Yuan
Appl. Sci. 2025, 15(1), 341; https://doi.org/10.3390/app15010341 - 1 Jan 2025
Viewed by 919
Abstract
Solid-state DC circuit breakers provide crucial support for the safe and reliable operation of low-voltage DC distribution networks. A hardware topology based on a cascaded structure with dual-stage, current-limiting, small-capacity, solid-state DC circuit breakers has been proposed. The hardware topology uses a series–parallel [...] Read more.
Solid-state DC circuit breakers provide crucial support for the safe and reliable operation of low-voltage DC distribution networks. A hardware topology based on a cascaded structure with dual-stage, current-limiting, small-capacity, solid-state DC circuit breakers has been proposed. The hardware topology uses a series–parallel configuration of cascaded SCR (thyristors) and MOSFETs (metal oxide semiconductor field-effect transistors) in the transfer branch, which enhances the breaking capacity of the transfer branch. Additionally, a secondary current-limiting circuit composed of an inductor and resistor in parallel is integrated at the front end of the transfer branch to effectively improve the current-limiting performance of the circuit breaker. Meanwhile, a dissipation branch is introduced on the fault side to reduce the energy consumption burden on surge arresters. For the power supply system of the hardware part, a capacitor-powered method is adopted for safety and efficiency, with a capacitor switch serially connected to the capacitor power supply for high-precision control of the power supply. Current detection branches are introduced into each branch to provide conditions for the on–off control of semiconductor switching devices and experimental data analysis. The high-frequency control of semiconductor devices is achieved using optocoupler signal isolation chips and high-speed drive chips through a microcontroller STM32. Simulation verification based on MATLAB/SIMULINK software and experimental prototype testing have been conducted, and the results show that the hardware topology is correct and effective. Full article
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11 pages, 4272 KiB  
Article
Indirect Method of Moisture Degree Evaluation in Varistors by Means of Dielectric Spectroscopy
by Krzysztof Walczak
Energies 2025, 18(1), 94; https://doi.org/10.3390/en18010094 - 30 Dec 2024
Viewed by 683
Abstract
Varistors, due to their unique properties, are materials commonly used in surge protection devices. Their reliability, however, requires periodic inspection, which should specifically include assessment of their moisture content. So far, no method has been developed that would directly and non-invasively allow for [...] Read more.
Varistors, due to their unique properties, are materials commonly used in surge protection devices. Their reliability, however, requires periodic inspection, which should specifically include assessment of their moisture content. So far, no method has been developed that would directly and non-invasively allow for the assessment of the moisture content of a varistor. In this work, an attempt was made to use dielectric spectroscopy for this purpose, i.e., measurements of dielectric parameters in the frequency domain. The tests were carried out on samples of materials based on silicon carbide. The result of the tests was the determination of the dependence of the dielectric response of the tested materials on moisture content, which after further tests may be the starting point for the development of a method for determining the moisture content of varistor surge arresters. Full article
(This article belongs to the Special Issue Innovation in High-Voltage Technology and Power Management)
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23 pages, 7672 KiB  
Article
Assessment of Insulation Coordination and Overvoltage for Utility Girds Integrated with Solar Farms
by Mansoor Soomro, Riaz Abbasi, Mazhar Baloch, Sohaib Tahir Chauhdary and Mokhi Maan Siddiqui
Energies 2024, 17(21), 5487; https://doi.org/10.3390/en17215487 - 2 Nov 2024
Viewed by 2479
Abstract
Due to the economic and environmental concerns associated with fossil fuels, many government and private organizations are progressively shifting towards the integration of solar farms with Utility Grids. However, these systems are facing insulation failure issues due to internal and external transient overvoltage’s, [...] Read more.
Due to the economic and environmental concerns associated with fossil fuels, many government and private organizations are progressively shifting towards the integration of solar farms with Utility Grids. However, these systems are facing insulation failure issues due to internal and external transient overvoltage’s, in which their shape, magnitude, and duration are unpredictable, and consequently, the insulation stress also becomes unpredictable. To ensure the safety and integrity of the system against any transient overvoltage event, it is important to carry out an insulation coordination analysis. The primary goal of this research work is to achieve this optimization in an economically viable manner, ensuring both operational stability and cost-effectiveness in the design of electrical equipment like surge Arresters. The research work presented in the literature does not fully evaluate all International Electrotechnical Commission (IEC) overvoltage classes as specified in the insulation coordination standards for Utility Grids integrated with solar farms. Therefore, this research paper investigates the impact of various transient and switching overvoltage conditions, as defined in the IEC 60071.4 Insulation Coordination Standard at the Solar and Utility Grid Electrical power system using PSCAD 4.6/EMTP Software. Five distinct simulation scenarios were developed to assess the systems’ resilience against insulation stress events. The proposed system was also examined with and without the application of a lightning surge arrester. Full article
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42 pages, 7745 KiB  
Opinion
Uncovering Diaphragm Cramp in SIDS and Other Sudden Unexpected Deaths
by Dov Jordan Gebien and Michael Eisenhut
Diagnostics 2024, 14(20), 2324; https://doi.org/10.3390/diagnostics14202324 - 18 Oct 2024
Cited by 1 | Viewed by 3438
Abstract
The diaphragm is the primary muscle of respiration. Here, we disclose a fascinating patient’s perspective that led, by clinical reasoning alone, to a novel mechanism of spontaneous respiratory arrests termed diaphragm cramp-contracture (DCC). Although the 7-year-old boy survived its paroxysmal nocturnal “bearhug pain [...] Read more.
The diaphragm is the primary muscle of respiration. Here, we disclose a fascinating patient’s perspective that led, by clinical reasoning alone, to a novel mechanism of spontaneous respiratory arrests termed diaphragm cramp-contracture (DCC). Although the 7-year-old boy survived its paroxysmal nocturnal “bearhug pain apnea” episodes, essentially by breathing out to breathe in, DCC could cause sudden unexpected deaths in children, especially infants. Diaphragm fatigue is central to the DCC hypothesis in SIDS. Most, if not all, SIDS risk factors contribute to it, such as male sex, young infancy, rebreathing, nicotine, overheating and viral infections. A workload surge by a roll to prone position or REM-sleep inactivation of airway dilator or respiratory accessory muscles can trigger pathological diaphragm excitation (e.g., spasms, flutter, cramp). Electromyography studies in preterm infants already show that diaphragm fatigue and sudden temporary failure by transient spasms induce apneas, hypopneas and forced expirations, all leading to hypoxemic episodes. By extension, prolonged spasm as a diaphragm cramp would induce sustained apnea with severe hypoxemia and cardiac arrest if not quickly aborted. This would cause a sudden, rapid, silent death consistent with SIDS. Moreover, a unique airway obstruction could develop where the hypercontracted diaphragm resists terminal inspiratory efforts by the accessory muscles. It would disappear postmortem. SIDS autopsy evidence consistent with DCC includes disrupted myofibers and contraction band necrosis as well as signs of agonal breathing from obstruction. Screening for diaphragm injury from hypoxemia, hyperthermia, viral myositis and excitation include serum CK-MM and skeletal troponin-I. Active excitation could be visualized on ultrasound or fluoroscopy and monitored by respiratory inductive plethysmography or electromyography. Full article
(This article belongs to the Section Pathology and Molecular Diagnostics)
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20 pages, 2003 KiB  
Article
A Novel Method for Online Diagnostic Analysis of Partial Discharge in Instrument Transformers and Surge Arresters from the Correlation of HFCT and IEC Methods
by Marcel Antonionni de Andrade Romano, André Melo de Morais, Marcus Vinicius Alves Nunes, Kaynan Maresch, Luiz Fernando Freitas-Gutierres, Ghendy Cardoso, Aécio de Lima Oliveira, Erick Finzi Martins, Cristian Hans Correa and Herber Cuadro Fontoura
Energies 2024, 17(19), 4921; https://doi.org/10.3390/en17194921 - 1 Oct 2024
Viewed by 1398
Abstract
In this work, a new methodology is proposed for the online and non-invasive extraction of partial discharge (PD) pulses from raw measurement data obtained using a simplified setup. This method enables the creation of sub-windows with optimized size, each containing a single candidate [...] Read more.
In this work, a new methodology is proposed for the online and non-invasive extraction of partial discharge (PD) pulses from raw measurement data obtained using a simplified setup. This method enables the creation of sub-windows with optimized size, each containing a single candidate PD pulse. The proposed approach integrates mathematical morphological filtering (MMF) with kurtosis, a first-order Savitzky-Golay smoothing filter, the Otsu method for thresholding, and a specific technique to associate each sub-window with the phase angle of the applied voltage waveform, enabling the construction of phase-resolved PD (PRPD) patterns. The methodology was validated against a commercial PD detection device adhering to the IEC (International Electrotechnical Commission) standard. Experimental results demonstrated that the proposed method, utilizing an off-the-shelf 8-bit resolution data acquisition system and a low-cost high-frequency current transformer (HFCT) sensor, effectively diagnoses and characterizes PD activity in high-voltage equipment, such as surge arresters and instrument transformers, even in noisy environments. It was able to characterize PD activity using only a few cycles of the applied voltage waveform and identify low amplitude PD pulses with low signal-to-noise ratio signals. Other contribution of this work is the diagnosis and fault signature obtained from a real surge arrester (SA) with a nominal voltage of 192 kV, corroborated by destructive disassembly and internal inspection of the tested equipment. This work provides a cost-effective and accurate tool for real-time PD monitoring, which can be embedded in hardware for continuous evaluation of electrical equipment integrity. Full article
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25 pages, 3094 KiB  
Article
Exosome-like Nanoparticles, High in Trans-δ-Viniferin Derivatives, Produced from Grape Cell Cultures: Preparation, Characterization, and Anticancer Properties
by Yury Shkryl, Zhargalma Tsydeneshieva, Ekaterina Menchinskaya, Tatiana Rusapetova, Olga Grishchenko, Anastasia Mironova, Dmitry Bulgakov, Tatiana Gorpenchenko, Vitaly Kazarin, Galina Tchernoded, Victor Bulgakov, Dmitry Aminin and Yulia Yugay
Biomedicines 2024, 12(9), 2142; https://doi.org/10.3390/biomedicines12092142 - 20 Sep 2024
Cited by 3 | Viewed by 3183
Abstract
Background: Recent interest in plant-derived exosome-like nanoparticles (ENs) has surged due to their therapeutic potential, which includes antioxidant, anti-inflammatory, and anticancer activities. These properties are attributed to their cargo of bioactive metabolites and other endogenous molecules. However, the properties of ENs isolated [...] Read more.
Background: Recent interest in plant-derived exosome-like nanoparticles (ENs) has surged due to their therapeutic potential, which includes antioxidant, anti-inflammatory, and anticancer activities. These properties are attributed to their cargo of bioactive metabolites and other endogenous molecules. However, the properties of ENs isolated from plant cell cultures remain less explored. Methods: In this investigation, grape callus-derived ENs (GCENs) were isolated using differential ultracentrifugation techniques. Structural analysis through electron microscopy, nanoparticle tracking analysis, and western blotting confirmed that GCENs qualify as exosome-like nanovesicles. Results: These GCENs contained significant amounts of microRNAs and proteins characteristic of plant-derived ENs, as well as trans-δ-viniferin, a notable stilbenoid known for its health-promoting properties. Functional assays revealed that the GCENs reduced the viability of the triple-negative breast cancer cell line MDA-MB-231 in a dose-dependent manner. Moreover, the GCENs exhibited negligible effects on the viability of normal human embryonic kidney (HEK) 293 cells, indicating selective cytotoxicity. Notably, treatment with these GCENs led to cell cycle arrest in the G1 phase and triggered apoptosis in the MDA-MB-231 cell line. Conclusions: Overall, this study underscores the potential of grape callus-derived nanovectors as natural carriers of stilbenoids and proposes their application as a novel and effective approach in the management of cancer. Full article
(This article belongs to the Section Nanomedicine and Nanobiology)
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16 pages, 7290 KiB  
Article
Application of Surge Arrester in Limiting Voltage Stress at Direct Current Breaker
by Mohammadamin Moghbeli, Shahab Mehraeen and Sudipta Sen
Appl. Sci. 2024, 14(18), 8319; https://doi.org/10.3390/app14188319 - 15 Sep 2024
Cited by 2 | Viewed by 1562
Abstract
Hybrid DC circuit breakers combine mechanical switches with a redirecting current path, typically controlled by power electronic devices, to prevent arcing during switch contact separation. The authors’ past work includes a bipolar hybrid DC circuit breaker that effectively redirects the fault current and [...] Read more.
Hybrid DC circuit breakers combine mechanical switches with a redirecting current path, typically controlled by power electronic devices, to prevent arcing during switch contact separation. The authors’ past work includes a bipolar hybrid DC circuit breaker that effectively redirects the fault current and returns it to the source. This reduces arcing between the mechanical breaker’s contacts and prevents large voltage overshoots across them. However, the breaker’s performance declines as the upstream line inductance increases, causing overvoltage. This work introduces a modification to the originally proposed hybrid DC breaker to make it suitable to use anywhere along DC grid lines. By using a switch-controlled surge arrester in parallel with the DC breaker, part of the arc energy is dissipated in the surge arrester, preventing an overvoltage across the mechanical switches. Based on the experimental results, the proposed method can effectively interrupt the fault current with minimal arcing and reduce the voltage stress across the mechanical switches. To address practical fault currents, tests at high fault currents (900 A) and voltage levels (500 V) are conducted and compared with simulation models and analytical studies. Furthermore, the application of the breaker for the protection of DC distribution grids is illustrated through simulations, and the procedure for designing the breaker components is explained. Full article
(This article belongs to the Special Issue Recent Advances in Smart Microgrids)
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20 pages, 1020 KiB  
Review
Beta-Blockers as an Immunologic and Autonomic Manipulator in Critically Ill Patients: A Review of the Recent Literature
by Akram M. Eraky, Yashwanth Yerramalla, Adnan Khan, Yasser Mokhtar, Mostafa Alamrosy, Amr Farag, Alisha Wright, Matthew Grounds and Nicole M. Gregorich
Int. J. Mol. Sci. 2024, 25(15), 8058; https://doi.org/10.3390/ijms25158058 - 24 Jul 2024
Cited by 5 | Viewed by 4530
Abstract
The autonomic nervous system plays a key role in maintaining body hemostasis through both the sympathetic and parasympathetic nervous systems. Sympathetic overstimulation as a reflex to multiple pathologies, such as septic shock, brain injury, cardiogenic shock, and cardiac arrest, could be harmful and [...] Read more.
The autonomic nervous system plays a key role in maintaining body hemostasis through both the sympathetic and parasympathetic nervous systems. Sympathetic overstimulation as a reflex to multiple pathologies, such as septic shock, brain injury, cardiogenic shock, and cardiac arrest, could be harmful and lead to autonomic and immunologic dysfunction. The continuous stimulation of the beta receptors on immune cells has an inhibitory effect on these cells and may lead to immunologic dysfunction through enhancing the production of anti-inflammatory cytokines, such as interleukin-10 (IL-10), and inhibiting the production of pro-inflammatory factors, such as interleukin-1B IL-1B and tissue necrotizing factor-alpha (TNF-alpha). Sympathetic overstimulation-induced autonomic dysfunction may also happen due to adrenergic receptor insensitivity or downregulation. Administering anti-adrenergic medication, such as beta-blockers, is a promising treatment to compensate against the undesired effects of adrenergic surge. Despite many misconceptions about beta-blockers, beta-blockers have shown a promising effect in decreasing mortality in patients with critical illness. In this review, we summarize the recently published articles that have discussed using beta-blockers as a promising treatment to decrease mortality in critically ill patients, such as patients with septic shock, traumatic brain injury, cardiogenic shock, acute decompensated heart failure, and electrical storm. We also discuss the potential pathophysiology of beta-blockers in various types of critical illness. More clinical trials are encouraged to evaluate the safety and effectiveness of beta-blockers in improving mortality among critically ill patients. Full article
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19 pages, 10721 KiB  
Article
Modeling and Experimental Validation on Current Uniformity Characteristics of Parallel Spiral Structure Surge Arrester in ±550 kV DC GIS
by Siyuan Liu, Liudan Wang, Shiyu Liu, Zhiyuan Liu and Yingsan Geng
Appl. Sci. 2024, 14(13), 5744; https://doi.org/10.3390/app14135744 - 1 Jul 2024
Cited by 1 | Viewed by 1226
Abstract
The employment of a multi-column parallel connection is intended to enhance the energy absorption capability and reliability of surge arresters. However, the disparity in reference voltage between each varistor column and the uneven current distribution may result in a reduction in performance or [...] Read more.
The employment of a multi-column parallel connection is intended to enhance the energy absorption capability and reliability of surge arresters. However, the disparity in reference voltage between each varistor column and the uneven current distribution may result in a reduction in performance or even failure of the surge arrester. The objective of this study is to investigate the spiral structure of a ±550 kV DC gas-insulated switchgear (GIS) parallel arrester and its influence on the current distribution characteristics. This research develops a model of a ±550 kV DC GIS arrester and performs an in-depth theoretical analysis using multi-physics field simulations. Subsequently, a ±66 kV miniature prototype is constructed, and the accuracy of the theoretical analysis and simulation results is validated by experiments, validating the effectiveness of the proposed method. This study calculates the self-generated inductance in the spiral structure of ZnO varistors using simulations. The influence of the self-generated inductance on the current distribution of the multi-column arrester when absorbing energy is further investigated. The results indicate that the self-generated inductance of the spiral structure can reduce the current deviation factor by 28–65%. This research provides a novel approach to improving current equalization in the parallel surge arresters of DC GISs for offshore wind power converter platforms. Full article
(This article belongs to the Section Electrical, Electronics and Communications Engineering)
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22 pages, 3149 KiB  
Article
Accurate Surge Arrester Modeling for Optimal Risk-Aware Lightning Protection Utilizing a Hybrid Monte Carlo–Particle Swarm Optimization Algorithm
by Amir Hossein Kimiai Asadi, Mohsen Eskandari and Hadi Delavari
Technologies 2024, 12(6), 88; https://doi.org/10.3390/technologies12060088 - 8 Jun 2024
Cited by 4 | Viewed by 2624
Abstract
The application of arresters is critical for the safe operation of electric grids against lightning. Arresters limit the consequences of lightning-induced over-voltages. However, surge arrester protection in electric grids is challenging due to the intrinsic complexities of distribution grids, including overhead lines and [...] Read more.
The application of arresters is critical for the safe operation of electric grids against lightning. Arresters limit the consequences of lightning-induced over-voltages. However, surge arrester protection in electric grids is challenging due to the intrinsic complexities of distribution grids, including overhead lines and power components such as transformers. In this paper, an optimal arrester placement technique is developed by proposing a multi-objective function that includes technical, safety and risk, and economic indices. However, an effective placement model demands a comprehensive and accurate modeling of an electric grid’s components. In this light, appropriate models of a grid’s components including an arrester, the earth, an oil-immersed transformer, overhead lines, and lightning-induced voltage are developed. To achieve accurate models, high-frequency transient mathematical models are developed for the grid’s components. Notably, to have an accurate model of the arrester, which critically impacts the performance of the arrester placement technique, a new arrester model is developed and evaluated based on real technical data from manufacturers such as Pars, Tridelta, and Siemens. Then, the proposed model is compared with the IEEE, Fernandez, and Pinceti models. The arrester model is incorporated in an optimization problem considering the performance of the over-voltage protection and the risk, technical, and economic indices, and it is solved using the particle swarm optimization (PSO) and Monte Carlo (MC) techniques. To validate the proposed arrester model and the placement technique, real data from the Chopoghloo feeder in Bahar, Hamedan, Iran, are simulated. The feeder is expanded over three different geographical areas, including rural, agricultural plain, and mountainous areas. Full article
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13 pages, 4166 KiB  
Article
Effect of Co-Doping of Al3+, In3+, and Y3+ on the Electrical Properties of Zinc Oxide Varistors under Pre-Synthesizing BiSbO4
by Bo Xu, Lei Wang, Mengfan Yang, Yu Xiang and Lingyun Liu
Materials 2024, 17(6), 1401; https://doi.org/10.3390/ma17061401 - 19 Mar 2024
Viewed by 1228
Abstract
Under the premise of using the solid-phase method to pre-sinter Bi2O3 and Sb2O3 into BiSbO4 as a substitute for equal amounts of Bi2O3 and Sb2O3 in the formula, the effects [...] Read more.
Under the premise of using the solid-phase method to pre-sinter Bi2O3 and Sb2O3 into BiSbO4 as a substitute for equal amounts of Bi2O3 and Sb2O3 in the formula, the effects of co-doping with In(NO3)3, Al(NO3)3, and Y(NO3)3 on the microstructure and electrical properties of ZnO varistors were studied. The experimental results show that with an increase in In3+-doped molar concentration, the leakage current of the ZnO varistor shows a rapid decrease and then a slow increase trend. However, the nonlinear coefficient is the opposite of it. With the combined effect of the rare earth element Y3+, the average grain size is significantly reduced, which leads to an increase in the voltage gradient. At the same time, a certain amount of doped In3+ and Al3+ is dissolved into the grains, resulting in a decrease in grain resistance and thus a low level of residual voltage. The varistor with 0.6 mol% In3+, 0.1 mol% Al3+, and 0.9 mol% Y3+ doping ratios exhibits excellent overall performance. The nonlinear coefficient is 62.2, with the leakage current being 1.46 µA/cm2 and the voltage gradient being 558 V/mm, and the residual voltage ratio is 1.73. The prepared co-doped ZnO varistors will provide better protection for metal oxide surge arresters. Full article
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17 pages, 3116 KiB  
Article
Exploring the Anticancer Potential of Traditional Thai Medicinal Plants: A Focus on Dracaena loureiri and Its Effects on Non-Small-Cell Lung Cancer
by Xiaomin Huang, Punnida Arjsri, Kamonwan Srisawad, Supachai Yodkeeree and Pornngarm Dejkriengkraikul
Plants 2024, 13(2), 290; https://doi.org/10.3390/plants13020290 - 18 Jan 2024
Cited by 13 | Viewed by 3590
Abstract
Non-small-cell lung cancer (NSCLC) is renowned for its aggressive and highly metastatic nature. In recent years, there has been a surge in interest regarding the therapeutic potential of traditional medicinal plants. Dracaena loureirin (D. loureirin), Ficus racemosa Linn. (F. racemosa [...] Read more.
Non-small-cell lung cancer (NSCLC) is renowned for its aggressive and highly metastatic nature. In recent years, there has been a surge in interest regarding the therapeutic potential of traditional medicinal plants. Dracaena loureirin (D. loureirin), Ficus racemosa Linn. (F. racemosa), and Harrisonia perforata (Blanco) Merr. (H. perforata) are prominent traditional medicinal herbs in Thailand, recognized for their diverse biological activities, including antipyretic and anti-inflammatory effects. However, their prospective anti-cancer properties against NSCLC remain largely unexplored. This study aimed to evaluate the anti-cancer attributes of ethanolic extracts obtained from D. loureiri (DLEE), F. racemosa (FREE), and H. perforata (HPEE) against the A549 lung adenocarcinoma cell lines. Sulforhodamine B (SRB) assay results revealed that only DLEE exhibited cytotoxic effects on A549 cells, whereas FREE and HPEE showed no such cytotoxicity. To elucidate the anti-cancer mechanisms of DLEE, cell cycle and apoptosis assays were performed. The findings demonstrated that DLEE inhibited cell proliferation and induced cell cycle arrest at the G0/G1 phase in A549 cells through the downregulation of key cell cycle regulator proteins, including cyclin D1, CDK-2, and CDK-4. Furthermore, DLEE treatment facilitated apoptosis in A549 cells by suppressing anti-apoptotic proteins (Bcl-2, Bcl-xl, and survivin) and enhancing apoptotic proteins (cleaved-caspase-3 and cleaved-PARP-1). In summary, our study provides novel insights into the significant anti-cancer properties of DLEE against A549 cells. This work represents the first report suggesting that DLEE has the capability to impede the growth of A549 lung adenocarcinoma cells through the induction of apoptosis. Full article
(This article belongs to the Special Issue Medicinal Plants: Advances in Phytochemistry and Ethnobotany II)
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26 pages, 2244 KiB  
Review
A Bibliometric and Comprehensive Review on Condition Monitoring of Metal Oxide Surge Arresters
by Tiago Goncalves Zacarias and Wilson Cesar Sant’Ana
Sensors 2024, 24(1), 235; https://doi.org/10.3390/s24010235 - 31 Dec 2023
Cited by 4 | Viewed by 2216
Abstract
This paper presents a literature review on the subject of Condition-Based Maintenance of surge arresters. Both a bibliometric analysis and traditional comprehensive research are presented. The bibliometric analysis is useful for obtaining insights about the literature. It quantitatively highlights relationships between journals, authors [...] Read more.
This paper presents a literature review on the subject of Condition-Based Maintenance of surge arresters. Both a bibliometric analysis and traditional comprehensive research are presented. The bibliometric analysis is useful for obtaining insights about the literature. It quantitatively highlights relationships between journals, authors and keywords (related to the monitoring methods) and reveals future trends for research based on the timeline of the keywords. The traditional comprehensive literature review is also presented. It summarizes the methods, their advantages and disadvantages and also points to some known measurement issues of the methods. Both online (leakage current, harmonic components, temperature, partial discharges, power loss and the counting of discharges) and offline (reference voltage, residual voltage, insulation resistance, polarization/depolarization, return voltage, microscopy, spectrometry, X-ray, RUS and the recent application of FRA) methods have been qualitatively analyzed. Full article
(This article belongs to the Special Issue Sensors for Fault Detection and Condition Monitoring)
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