Treatment of the known half-sandwich complexes of the type [(η
6-C
6H
6)RuCl
2(P(OR)
3)] (R = Me or Ph) with SnCl
2 yielded three new half-sandwich ruthenium complexes (
C1–
C3): [(η
6-C
6
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Treatment of the known half-sandwich complexes of the type [(η
6-C
6H
6)RuCl
2(P(OR)
3)] (R = Me or Ph) with SnCl
2 yielded three new half-sandwich ruthenium complexes (
C1–
C3): [(η
6-C
6H
6)RuCl(SnCl
3)(P(OMe)
3)] (
C1), [(η
6-C
6H
6)RuCl(SnCl
3)(P(OPh)
3)] (
C2) and the bis-stannyl complex [(η
6-C
6H
6)Ru(SnCl
3)
2(P(OMe)
3)] (
C3) by facile insertion of SnCl
2 into the Ru–Cl bonds. Treatment of the known complexes [(η
6-C
6H
6)RuCl(SnCl
3)(PPh
3)] and [(η
6-C
6H
6)RuCl
2(PPh
3)] with 4-dimethylaminopyridine (DAMP) and ammonium tetrafluoroborate afforded the complex salts: [(η
6-C
6H
6)Ru(SnCl
3)(PPh
3)(DAMP)]
+BF
4− (
C4) and [(η
6-C
6H
6)RuCl(PPh
3)(DAMP)]
+BF
4− (
C5) respectively. Complexes
C1–
C5 have been fully characterized by spectroscopic means (IR, UV–vis, multinuclear NMR, ESI–MS) and their thermal behaviour elucidated by thermal gravimetric analysis (TGA). Structural characterization by single crystal X-ray crystallography of the novel complex
C2 and [(η
6-C
6H
6)RuCl
2(P(OPh)
3)], the latter having escaped elucidation by this method, is also reported. Finally, the cytotoxicity of the complexes was determined on the A2780 (human ovarian cancer), A2780cisR (human ovarian
cis-platin-resistant cancer), and the HEK293 (human embryonic kidney) cell lines and discussed, and an attempt is made to elucidate the effect of the stannyl ligand on cytotoxicity.
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