Search Results (319)

Transition metal complexes that can serve as photosensitizers (PSs) have attracted considerable scientific interest owing to their potential applications in photodynamic therapy (PDT), triplet-triplet annihilation for energy upconversion (TTA UC), photocatalysis, and time-resolved bioimaging techniques. In many of these applications, the efficiency of intermolecular triplet-triplet energy transfer (TTET) between the photosensitizer and acceptor is largely determined by the triplet excited-state lifetime of the photosensitizer. One of the most efficient strategies for extending the triplet lifetimes of transition metal complexes is the incorporation of organic chromophores possessing long-lived intraligand (³IL) excited states into the coordination sphere of transition metal complexes. Polycyclic aromatic hydrocarbons, particularly anthracene- and pyrene-based chromophores, have emerged as especially attractive building blocks for this purpose. The current contribution highlights the role of pyrene and anthracene groups in controlling the photophysical properties of cyclometalated iridium(III) metal complexes, with an emphasis on their applications as photosensitizers. Particular attention is devoted to elucidating the relationships between molecular structure and excited-state properties. A detailed discussion of these relationships has been performed for three classes of cyclometalated iridium(III) complexes: (1) charge-neutral Ir(III) complexes including pyrene and anthracene motifs, (2) cationic bis-cyclometalated iridium(III) complexes bearing pyrene-functionalized ligands, and (3) cationic mono- and bis-cyclometalated iridium(III) complexes bearing anthracene-functionalized ligands. Full article

Background: The skin, as the largest organ of the human body, plays a crucial role in protection, immunity and homeostasis. Its exposure to environmental and internal factors contributes to the development of various dermatological conditions. Conventional treatments are often associated with adverse effects and increased resistance. This review aims to explore the growing role of phytotherapeutic approaches in dermatology, along with mapping recent research trends in the field. Methods: The paper presents three parts: the first part highlights the mapping of interest in the addressed topic through a systematic selection of the specialized literature using the Web of Science database. A bibliometric analysis was conducted using the Web of Science Core Collection, with data visualized in VOSviewer to identify publication trends, keyword clusters, and collaboration networks across European countries. Subsequently, in the second part of the review, the main topical topics regarding the skin were addressed (the immune and non-immune response system, microbiome composition and physiological responses in different situations). The third part of the paper addresses phytotherapy targeted at the dermatological sphere and controlled release therapeutic systems. Results: The analysis identified a total of 267 publications, with a significant increase in recent years. Key research clusters included phytochemical-based therapies, nanocarrier systems, and inflammatory skin conditions. Keyword co-occurrence analysis revealed emerging trends in nanoformulations and targeted delivery systems. The main research groups focused on polyphenols, antioxidant activity, anti-inflammatory effects and advanced delivery systems, such as nanoparticles and liposomes. In addition, innovative formulations have improved bioavailability and targeted administration. Conclusions: Phytotherapeutic approaches represent a promising alternative to conventional dermatological treatments, offering effective, safer and more sustainable solutions. The integration of natural compounds with modern delivery systems improves therapeutic outcomes and minimizes side effects, supporting their increasing relevance in clinical and pharmaceutical research. Full article

Background/Objectives: Cancer-related terminology is not merely descriptive and plays a critical role in shaping emotional responses, personal identity, and communication across clinical, social, and public spheres. Despite growing interest in the psychosocial dimensions of illness language, few studies have centered the lived experiences of individuals navigating cancer through the lens of terminology. This study explores how people living with and beyond cancer perceive, interpret, and emotionally respond to cancer-related language, focusing on the way terminology influences identity, stigma, and communicative interaction. Methods: A sequential mixed-methods design was employed. The quantitative phase involved 146 participants with a cancer diagnosis completing a structured questionnaire on preferred terminology and emotional impact. The qualitative phase followed, using open-ended questionnaires with 11 participants to deepen understanding of linguistic experiences. Thematic content analysis was used to identify patterns across narratives. Results: These findings reveal that labels such as “cancer patient” evoke strong negative emotional reactions, associated with stigma, fear, and identity reduction. Person-first and context-sensitive language was perceived as more respectful and empowering. Emotional responses to language varied widely, from fear to neutrality, shaped by speaker role, context, and time since diagnosis. Media representations were often seen as dramatizing or moralizing, reinforcing the need for communicative clarity, empathy, and education in both clinical and public discourse. Conclusions: Cancer-related language is a powerful psychosocial force. It shapes how individuals are seen and see themselves and can either reinforce stigma or foster dignity and resilience. This study highlights the urgent need for person-centered, context-aware communication practices across healthcare, media, and society. Full article

High-order Poincaré sphere (HOPS) beams have attracted tremendous interest due to their complex polarization and phase characteristics. However, manipulating the second harmonics generation (SHG) of HOPS beams is still challenging. Here, we developed a vector-coupled wave model to predict petal-shaped intensity patterns and reveal a linear correlation between petal number and topological order (n = 2 → 4). Moreover, we experimentally investigated the multidimensional regulation of SHG in HOPS beams through tailored phase-matching strategies. By employing three distinct configurations—(i) type-I phase matching, (ii) type-II phase matching, and (iii) orthogonally arranged BBO crystals based on Type-I phase matching—we establish a comprehensive framework for controlling the spatial and polarization properties of SHG in n = 2 HOPS beams. These results advance the manipulation of structured light in nonlinear optics, providing insights for optimizing applications in optical communication and polarization imaging. Full article

The technological promise of nonlinear optical (NLO) compounds has stimulated intense interest in optoelectronic devices, data storage, photonics, and anticancer therapy. Thiosemicarbazone ruthenium materials are of growing interest because of their tunable ligand framework and coordination sphere, allowing fine control over geometry, electronics, and functional properties. Here, we report an N-substituted salicylaldehyde thiosemicarbazone ligand and a series of octahedral Ru(III) complexes bearing triphenylphosphine or triphenylarsine and halide (Cl, Br) co-ligands. The complexes were characterized by elemental analysis, FT-IR, UV–Vis, EPR, mass spectrometry, and magnetic susceptibility measurements, which together confirm NS-chelation to a low-spin Ru(III) center in a distorted octahedral environment. Their photophysical and NLO responses were assessed by UV–Vis spectroscopy and powder second-harmonic generation measurements (Kurtz–Perry method), revealing promising NLO behavior. In parallel, antioxidant activity and in vitro anticancer effects against HeLa cells were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cytotoxicity assays. These results provide insight into ligand-controlled structure–activity relationships, in which the halide (Cl/Br) and ancillary triarylphosphine co-ligands regulate electronic interactions and lipophilicity and ultimately increase biological performance, underscoring the dual materials and medicinal potential of these Ru(III) complexes. Full article

This paper investigates cylindrical sphere packings, that is, patterns of uniform spheres with mutually disjoint interiors which are all tangent to a common cylinder. The key unifying themes are the existence and uniqueness of hexagonal packings, in which each sphere is tangent to six others. Constructions are both intuitive and subtle, but result in the complete characterization in terms of integer parameter pairs $(m,n)$. Interesting questions in rigidity and density are encountered. Density questions arise because the packings, being of equal diameter, lie within the space between inner and outer cylinders. This density problem hovers between the 2D and 3D sphere packing cases, and though it is not solved here, it is conjectured that the hexagonal packings are densest for the countable number of cylinders which support them. Other geometric objects are along for the ride, including equilateral triangles and the packings’ dual graphs, which are associated with patterns of carbon atoms forming buckytubes. Interesting structural rigidity questions also arise. Full article

In the aviation industry the so-called ballistic impact of small accidental or human-made sources on aircraft elements during their service life encompasses several scenarios of practical interest. The experimental assessment of ballistic impact requires dedicated infrastructures (such as the light-gas gun system utilized in this study) and exhibits intrinsic difficulties, mainly concerning the proper acceleration of a projectile and the accurate measurement by a high-speed camera of its (inlet and outlet) velocity. As a first objective, this study aimed at characterizing the dynamic response of fiber metal laminates, manufactured ad hoc by the authors with two different stacking sequences currently not available in commerce. The layups included aluminum 2024 T3 and aramid fiber-reinforced prepregs, leading through specific treatments to excellent specific properties. The collision of the laminate with a 25 g, 9 mm radius steel sphere, traveling at speeds ranging from 90 to 145 m/s, caused a variety of scenarios: partial or complete penetration, with the projectile passing through and continuing its trajectory, remaining stuck in the sample (embedment) or even being bounced back (ricochet). The experimental information led to the estimation, for each typology of sample, of a conventional ballistic limit according to the Lambert-Jonas approximation, as a second objective, these data were utilized to validate an accurate heterogeneous model of the samples developed in the ABAQUS^® platform, discretized by finite elements in explicit dynamics and including geometric nonlinearity and contact. We describe plasticity and damage of the metal layers by the Johnson–Cook phenomenological model, progressive failure in the fiber-reinforced plies through a 2D Hashin criterion with damage evolution, and interlaminar debonding at multiple cohesive interfaces governed by the Benzeggagh–Kenane criterion. The outlet speed of the bullet measured during the experiments was retrieved correctly by this model, and a satisfactory agreement of the finite element predictions was found with the deformation patterns and the damage mechanisms identified by post mortem visual inspection. Finally, several discussion points are raised, concerning the robustness of the numerical analyses, the reliability of the constitutive modeling and the identification of the governing parameters. Full article

The management of religious diversity has become a central concern for European countries, particularly within the sphere of education. It has been questioned before the European Court of Human Rights (ECtHR) approach towards religious diversity through indirect discrimination and the proportionality test. While this approach has yielded positive outcomes in workplace contexts, its application in educational settings reveals distinctive challenges, especially given the pluralistic and often contested nature of public education in Europe. This article undertakes a comparative analysis of how the ECtHR’s development of concepts such as indirect discrimination and differential treatment in educational cases shapes the broader understanding of religious diversity. It examines the Court’s evolving and at times inconsistent jurisprudence, which oscillates between affirming individual rights and upholding collective interests such as social cohesion and secularism. The analysis highlights that the management of religious diversity in education cannot rely solely on legal accommodation; it requires a nuanced interplay between legal standards, institutional practices, and societal engagement. Full article

This study is grounded in the premise that local media should be understood beyond a market-oriented framework, with their social role theoretically redefined through the concept of symbolic capital. The central thesis is that the survival of local media must be regarded primarily as a matter of public interest and as a prerequisite for strengthening the democratic capacity of communities in contemporary socio-communicative contexts. Representative examples of both active and defunct local media in Serbia were analyzed to assess how, across different historical periods, they contributed to the formation and transformation of symbolic capital in local communities. The theoretical framework draws on Pierre Bourdieu’s concept of symbolic capital and Jürgen Habermas’ theory of the public sphere. The analysis indicates that local media functioned as institutional carriers of legitimacy during the socialist period, as spaces of resistance during the transitional period, and as sources of moral and professional capital in the contemporary era. Nevertheless, current project-based funding models and precarious working conditions undermine their autonomy and long-term sustainability. It is therefore concluded that the disappearance of local media represents not merely an economic problem but also a profound symbolic and democratic loss, as communities lose spaces of trust, dialogue, and public representation. Full article

The objective of this article is to examine how alternative digital platforms can be designed and governed as public-interest infrastructures capable of supporting democratic deliberation in the contemporary digital public sphere. Drawing on deliberative democratic theory, the article develops a normative framework for evaluating participatory digital infrastructures and applies it to a qualitative, theory-driven case study of Decidim, an open-source participatory platform originally developed by the Barcelona City Council. Methodologically, the study combines normative analysis with qualitative documentary analysis of official platform documentation, peer-reviewed academic literature, and the institutional and technical features of the platform. The analysis shows that Decidim operationalises key deliberative principles—such as inclusion, publicity, reason-giving, transparency, traceability, and participatory governance—through its institutional design, governance model, and deliberative affordances. The findings demonstrate that algorithmic systems and digital infrastructures are not inherently incompatible with democratic values, but can be intentionally engineered to support public deliberation and democratic will-formation. The article concludes that the reconstruction of participatory digital infrastructures as public goods constitutes a democratic imperative, requiring sustained institutional commitment, political will, and a reconceptualisation of platform design as a domain of democratic governance. Full article

This qualitative study explores the construction of financial literacy in the context of retirement among young women in Israel, in light of available cultural schemas. The research challenges economic models that rely solely on assumptions of rationality and self-interest, offering a qualitative expansion of the behavioral foundations of financial literacy. Drawing on in-depth interviews of 46 young women, the findings reveal that their perceptions and choices in the financial domain are profoundly shaped by gendered “schemas of devotion”: devotion to work and devotion to family. These schemas give rise to two orientations: women who are more engaged in the financial sphere, characterized by initiative and reflexivity (resistance to the gendered schemas), and women who are more detached, displaying passivity and emotional distance (adoption of these schemas). The study demonstrates how these cultural models contribute to either the reproduction or transformation of gender inequality in retirement. Its main contribution lies in broadening the discipline of economics and positioning gender as a central analytical category—one that is vital for developing more sensitive policies capable of improving the functioning of the economic system and reducing gender gaps. Full article

The development of anisotropic gold nanostructures supporting localized surface plasmon (LSP) resonances in the near-infrared (NIR) biological window is of great interest for diagnostic and therapeutic nanotechnologies. Here, we report gold open-shell nanoparticles (AuOSNs), a symmetry-broken nanoshell architecture exhibiting strong NIR surface-enhanced Raman scattering (SERS) activity. AuOSNs were fabricated via a surfactant-free strategy combining bottom-up silica sphere assembly with a simple top-down gold deposition process, without using highly cytotoxic surfactants such as cetyltrimethylammonium bromide (CTAB). Boundary element method (BEM) simulations revealed that the asymmetric open-shell geometry induces NIR LSP resonances with pronounced electromagnetic field localization near the opening edges, depending on excitation configuration. Consistent with these predictions, extinction spectra of AuOSNs dispersed in water showed an LSP resonance peak at ~793 nm, close to the 785 nm excitation wavelength for SERS. In aqueous dispersion, AuOSNs modified with 4-mercaptobenzoic acid (4-MBA) exhibited strong SERS activity with enhancement factors of ~10⁶. Furthermore, polyethylene glycol (PEG)-modified MBA/AuOSNs showed negligible cytotoxicity in vitro. SERS imaging confirmed that PEG/MBA/AuOSNs enable visualization of HeLa cells via characteristic MBA SERS signals. These results demonstrate that surfactant-free AuOSNs provide a biocompatible platform for NIR-excited SERS sensing and cellular imaging, highlighting their potential in plasmonic bioimaging applications. Full article

Stormwater systems can improve public health and environmental and social conditions in cities, but their effectiveness may be blocked by fragmented project plans and lack of stakeholder support. Systems thinking and institutional analysis were used to assess how these barriers can be addressed and how stormwater systems can become agents of change to support livable and healthy cities. Projects and professional activities were studied to assess stakeholder involvement from low-to-high levels of power and interest in projects. Community stakeholders were developers and social entrepreneurs, government stakeholders included elected officials and staff, and support groups represented engineers, public agency facilitators, and urban planners. Stormwater projects and systems are a focus for engineers, but they often lose their stormwater identify when they are combined with other development projects. The workplace for such projects is the public arena, where cities seek aspirational goals by applying integration through comprehensive planning. However, development projects sometimes fail to comply with the plans. Stormwater may provide the spark for multi-purpose projects as cities must sustain conveyance corridors for connectivity of major flows. However, fragmented project development spurred by rigid capital improvement programs and lack of a path to develop stormwater system connectivity through comprehensive planning and development present barriers. Effective governance is the core issue, and most power is with elected officials, who require public support. The analysis shows need for a road map to utilize stakeholder power to promote stormwater advances by raising awareness and developing practical approaches that work in the spheres of comprehensive planning and capital improvement programming. The road map could be supported by an integrated body of knowledge to frame stormwater management as a combination of urban planning, engineering, and public administration and to encourage these communities to develop a cooperative road map through work among their professional associations. Full article

Since the 1990s, but especially in the early 21st century, a new family of right-wing populist parties has become a stable feature of Western European party systems. These parties, linked by several studies to new cleavages related to globalization processes and values changes which have happened since the late 20th century, are also marked by a new use of religion. In their worldview, this latter is indeed mainly an identity and civilization marker, related to the belonging, rather than believing or behaving, dimension. As a consequence, while they promote Christian symbols in the public sphere and are actively engaged in debates related to morality politics and multicultural society, they also contribute to processes of banalization and culturalization of faith, and to the delegitimization of religious leaders and institutions. For this reason, the scholarly community is divided about their role as promoters of religion, or, rather, as (maybe unintentional) agents of secularization. This article will try to contribute to this discussion by analyzing the Italian case. Italy is indeed an interesting laboratory for the study of right-wing populism, with the development over the past few decades of two state-wide parties belonging to the right-wing populist family, the League and Brothers of Italy, both currently part of the Meloni cabinet. The article will analyze the historical roots of the parties and their developments, their manifestos, their policy proposals, and their relations with religious institutions and symbols to reflect on the two parties’ uses of religion for political aims, and their meaning in relation to the above-mentioned theoretical debates. Full article

In this work, polylactic acid (PLA)/poly(butylene adipate-coterephthalate) (PBAT) composites containing nanomagnetite particles were developed for electromagnetic shielding. The nanomagnetite particles acted not only as a conductive filler but also as a reinforced agent and compatibilizer for PLA/PBAT blends. The effect of surface treatments by the silicon coupling agent (SCA) under different pH conditions and with other substances (silica and dopamine (DA)) were investigated in particular. The composites were prepared by thermal mixing and characterized by Fourier-transform infrared spectroscopy (FTRI), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), transparency electron microscopy (TEM) and tensile testing. The results show that the interface between the PBAT spheres and the PLA matrix was improved after the addition of magnetite particles treated with SCA or PDA. It is interesting to find that under acidic conditions, SCA acted more efficiently due to the chemical reaction of SCA with the hydroxyl groups on the surface of the magnetite particles, which resulted in chemical improvement. Tensile strength increased about 20%, while elongation also increased about 15%. The fracture surface under SEM clearly showed plastic deformation, which contributed to an improvement in mechanical properties, especially toughness. Full article