Search Results (5,357)

The aim of the study was to develop hybrid nanomaterials based on monodisperse silica spheres as carriers for silver nanoparticles (AgNPs) or bismuth nanoparticles (BiNPs) and to evaluate their antimicrobial properties. Silica spheres were synthesized using a modified Stöber method, either unmodified or functionalized with (3-aminopropyl)triethoxysilane (APTES), prior to AgNP or BiNP deposition. The materials were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), inductively coupled plasma optical emission spectroscopy (ICP-OES), and zeta potential measurements, while antimicrobial activity was assessed by microdilution against Gram-positive (Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Enterococcus faecium) and Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa), with Helicobacter pylori as a clinical model. The results show that both SiO₂-AgNP and SiO₂-BiNP composites completely inhibited H. pylori and showed high activity against other pathogens, although P. aeruginosa remained less susceptible. Functionalization of AgNP-coated samples with APTES promoted uniform distribution of AgNPs, with the minimum bactericidal concentration (MBC) to minimum inhibitory concentration (MIC) ratios ranging from 1 to 4, confirming a bactericidal rather than bacteriostatic effect. In contrast, BiNP-coated samples without APTES exhibited lower MIC values from 74 to 595 μg mL⁻¹, consistent with increased Bi³⁺ release from amorphous phases. This indicates the antimicrobial potential, highlighting the role of surface functionalization in regulating ion release and biological performance, and suggesting applications in the biomedical and food industries. Full article

Mesenchymal stem cells are widely cultivated in stirred tank bioreactors. Due to their adhesion properties, they are attached to small spherical spheres called microcarriers. To understand the hydromechanical stresses encountered by the cells, it is essential to characterize the flow using the PIV technique. However, the usual solid–liquid system used in cell cultures has poor optical properties. Thus, shifting to one with better optical properties, while respecting the physical characteristics, is mandatory to achieve a relevant representation. PMMA microparticles suspended with 61 wt% ammonium thiocyanate solution NH${}_4$SCN were found to be a robust candidate. The refractive index (RI) of both sides is of the order of 1.491 with a density ratio of ${\rho }_f/{\rho }_p\approx$ 0.96, and particle size averaged around 168 m. Using the RIM-PIV (refractive index matched particle image velocimetry) technique for a 0.7 L volume stirred tank equipped with an HTPG down-pumping axial impeller and operating at full homogeneous speed $N=150$ rpm, mean and turbulence quantities of the liquid phase were measured as a function of PMMA particle volume fractions ${\alpha }_p$, which ranged from 0.5 to 3 v%. This corresponds to a particle number density of $n=12$ particles/mm${}^3$, which is considered original and challenging for the PIV technique. At 3 v%, the addition of particles dampened the turbulent kinetic energy (TKE) of the liquid phase locally by 20% near the impeller. This impact became trivial (<10%) at the local-average level. The structure and direction of the recirculation loop also shifted. Full article

The design of spacecraft protection against orbital debris (OD) is generally based on experiments and models involving spherical projectiles. However, observations of collision fragments from ground-based satellite impact experiments have shown that orbital debris is non-spherical in shape. To accommodate non-spherical projectiles in spacecraft protection measures, a relationship between spherical projectiles and their threat-equivalent non-spherical counterparts was established. Cylindrical projectiles featuring adjustable Length-to-Diameter (L/D) ratios were employed to simulate the projectile shape effect on the bumper performance under hypervelocity impact. The L/D ratio spanned a range from L/D = 1/3, representing a “flake” shape, through L/D = 1 for a “nugget” configuration and extended up to L/D = 5/3, representing a “straight rod” configuration. The numerical analysis utilized the smoothed-particle hydrodynamics technique, demonstrating that projectile geometry significantly influenced the threat posed by projectile fragments to the objects behind the bumper. The established projectile threat relationship can be applied to assess the ability of the existing OD bumpers to withstand non-spherical projectiles by representing them with an equivalent sphere. Utilizing this approach can contribute to decreasing uncertainty and enhancing the protection of spacecraft when encountering irregularly shaped OD particles. Full article

Adsorption studies of ciprofloxacine (CPX) and lidocaine (LID) emerging contaminants were performed on two fibrous Mg clays from the Madrid basin and Senegal. The samples were characterized by X-ray diffraction, ICP major element analysis, infrared spectroscopy, thermal analysis, optical petrography, scanning and transmission electron microscopy, cation exchange capacity (CEC), and N₂-BET analysis. Two mineral assemblages were established. Assemblage 1 mainly consists of sepiolite and minor trioctahedral smectite, while assemblage 2 is mostly composed of palygorskite, which is associated with dioctahedral smectite. The sorption was fast and reached equilibrium in 2 h. Fibrous Mg clays showed a higher adsorption capacity for CPX than for LID in the conditions studied. CPX adsorption on sepiolite and palygorskite can be the result of the combination of various mechanisms: ion exchange with permanently charged sites, electrostatic attractions with external surfaces, and an inner sphere complex with broken edges. LID adsorption mainly occurs by ion exchange and electrostatic interaction with the external surfaces of the clays. Dioctahedral smectite, as an associated phase, contributed to a higher removal percentage in palygorskite samples. By contrast, the trioctahedral smectite did not play a significant role in the adsorption of the samples with sepiolite. The mesoporous structure, high surface area, and moderate cation exchange of fibrous clays play a key role in the sorption process of CPX and LID. Full article

In this paper, the uniqueness of steady Schwarzschild gradient Ricci solitons is studied. The role of the weight functions is analyzed. The generalized steady Schwarzschild gradient Ricci solitons are investigated; the implications of the rotational ansatz of Bryant are developed; and the new Generalized Schwarzschildsteady gradient solitons are defined. The aspects of the weight functions of the latter type of solitons are researched as well. The new most-accurate curvature bound of the steady Ricci gradient solitons is provided. The uniqueness of the Schwarzschild solitons is discussed. The Ricci flow is reconciled with the Einstein Field Equations such that the weight functions are utilized to spell out the determinant of the metric tensor, the procedure for which is commented on following the use of the appropriate geometrical objects. The mean curvature is discussed. The configurations of the observer are issued from the geodesics spheres of the solitonic structures. Full article

The compound 3-((benzyloxy)carbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid was successfully synthesized. High-quality crystals were obtained, and its X-ray structure was solved and refined by Hirshfeld atom refinement using custom aspherical scattering factors with the Olex2/NoSphereA2 package. Hydrogen bonding interactions lead to head-to-head carboxylic acid dimer formation. A positional disorder for the bridging H-atom was detected and modeled to two parts in a 0.85:0.15 ratio. Detailed comparison with a neutron diffraction study of benzoic acid at the same temperature (100 K) demonstrates that the E–H-bond distances in the title compound are in excellent agreement (differing less than 1%) and the displacement ellipsoids volumes to the model are also in excellent agreement to the neutron diffraction structure. Moreover, both the variation in refined disorder occupancy and differences in C=O and C–O lengths of the disordered carboxylic acids in the two structures track well with their dimer O···O separations. This is longer by 0.023 Å in the structure of the title compound than in that of benzoic acid. A database search was conducted and used for comparison of the title compound to other high-quality structures of bicyclo[1.1.1]pentane-containing species. Full article

In this work, we construct a multiple solutions theory based on a membrane shape equation. The membrane shape of a vesicle or a red blood cell is determined using the Zhongcan–Helfrich shape equation. These spherical solutions, which have an identical radius $r_s$ but different center positions, can be described by the same equation: $\varphi -\rho /r_s=0$. A degeneracy for the spherical solutions exists, leading to multisphere solutions with the same radius. Therefore, there can be multiple solutions for the sphere equilibrium shape equation, and these need to satisfy a quadratic equation. The quadratic equation has a maximum of two roots. We also find that the multiple solutions should be in a line to undergo rotational symmetry. We use the quadratic equation to compute the sphere radius, together with a membrane surface constraint condition, to obtain the number of small spheres. We ensure matching with the energy constraint condition to determine the stability of the full solutions. The method is then extended into the myelin formation of red blood cells. Our numerical calculations show excellent agreement with the experimental results and enable the comprehensive investigation of cell fission and fusion phenomena. Additionally, we have predicted the existence of the bifurcation phenomenon in membrane growth and proposed a control strategy. Full article

Short-range forces enable peridynamics to simulate impact, yet it demands a computationally expensive contact search and includes no intrinsic damping. A significantly more efficient solution is the coupled dual-horizon peridynamics–discrete element method approach, which provides a robust framework for modeling fracture. The peridynamics component handles the nonlocal continuum mechanics capabilities to predict material damage and fracture, while the discrete element method captures discrete particle behavior. Whereas existing peridynamics–discrete element method approaches assign discrete element method particles to many or all surface peridynamics points, the proposed method integrates dual-horizon peridynamics with a single discrete element particle representing each object. Contact forces are computed once per discrete element pair and mapped to overlapping peridynamics points in proportion to shared volume, conserving linear momentum. Benchmark sphere-on-plate impact demonstrates prediction of peak contact force, rebound velocity, and plate deflection within 5% of theoretical results found in the literature, while decreasing neighbour-search cost by more than an order of magnitude. This validated force-transfer mechanism lays the groundwork for future extension to fully resolved fracture and fragmentation. Full article

Objectives: The systematic increase in the number of overweight and obese people in recent years has led to the recognition of this condition as a chronic, non-infectious disease of civilization, declared a global epidemic by WHO in 1997. This phenomenon is particularly dangerous in children, because it negatively affects their later existence in the health, mental and social spheres. This phenomenon is particularly concerning in the pediatric population, as it may have long-term adverse effects on physical health, psychological well-being, and social functioning. Objective: The aim of this study was to assess anthropometric parameters and physical fitness using the EUROFIT test in children and adolescents diagnosed with obesity. Materials and Methods: The study group consisted of 123 pediatric patients attending the Endocrinology and Diabetology Clinic and Pediatric Rehabilitation IP-CZD aged 8–16 (64 boys—52% and 59 girls—48%) with diagnosed simple obesity. Obesity was diagnosed according to the CDC standard using percentile charts from the OLAF study. Physical fitness was assessed using the EUROFIT test using 8 samples, and body mass composition was examined using the bioimpedance method with the BC 418 Tanita analyzer. Results: The results of our own research obtained in this study were compared to population standards. The total results of the EUROFIT test in the study group were statistically significantly lower than the norm. The results of the balance, upper limb movement speed, jumping, trunk strength, functional strength and agility tests were lower than the norm, the flexibility result was within the norm, and only hand strength was higher than the norm. In 4 out of 8 fitness tests, girls achieved significantly better results than boys. Conclusions: Reduced physical fitness is characteristic of children and adolescents with simple obesity. Worse physical fitness shows significant correlations with the results of anthropometric measurements. Full article

This study examines Egypt’s evolving role as a middle power through the lens of niche diplomacy. It analyzes how Cairo leverages its strategic advantages to assert influence within an increasingly multipolar international order. Egypt’s global profile has expanded beyond its immediate regional sphere through four key domains: mediation, its bid to serve as an energy hub, its geopolitical positioning at the Arab-African and Mediterranean crossroads, and its promotion of religious, cultural, and heritage diplomacy. The analysis shows that these niches enable Egypt to maintain agency, manage external dependencies, and project influence despite structural vulnerabilities. The study advances the literature on middle powers by illustrating how a Global South state adapts niche diplomacy to contemporary geopolitical pressures. Egypt’s case demonstrates that structural geography, historical legacy, and interregional identity can sustain middle-power relevance, extending the niche diplomacy concept beyond models centered on wealth or ideational leadership. Full article

Metal additive manufacturing represents the most promising application for Three-dimensional printing systems. Gas atomization is an important method for the preparation of metal powders. In this work, aluminum powders were prepared via vacuum induction atomization. Morphology and microstructure were investigated. Results demonstrated that optimal atomization occurred at 3 MPa with a 2.5 mm delivery tube diameter, yielding powders with an average particle size of 63.8 μm and a sphericity of more than 90%. Variations in droplet size caused differential cooling rates, enabling rapidly solidified small droplets to adhere to incompletely cooled large droplets and form satellite spheres. Quantitative analysis confirmed a positive correlation between metal powder particle size and surface satellite spheres. Large droplets exhibited long cooling times, resulting in more pronounced dendritic microstructures. This study provides theoretical insights for the preparation of metal powders. Full article

Despite growing interest in humanized childbirth practices, there is still little qualitative research exploring women’s perspectives on vocalization during labor. The present study aims to analyze women’s experiences with the use of vocalization in the first and second stages of labor. A descriptive and exploratory qualitative study was conducted using semi-structured interviews with 16 women in the postpartum period between February and April 2024. Participants were recruited by convenience sampling, and data saturation was achieved when no new themes emerged from the interviews. Thematic analysis was performed using IRaMuTeQ (version 0.8 alpha 7) software. The textual corpus generated allowed classification into five thematic categories: Vocalization as an instinctive expression in natural childbirth; Functionality of vocalization during labor; Medicalized childbirth and natural childbirth; Fears during childbirth and their contributing factors; Typology of vocalization in labor. We conclude that many women reported that vocalization during labor is instinctive and functional, providing pain relief, but also serving as a means of communication, empowering women. Its expression can be strongly influenced by sociocultural, emotional, and contextual factors in each woman’s particular sphere. These findings, although limited to a specific population, suggest that healthcare professionals should consider vocalization as an individualized support tool, taking cultural differences into account. Full article

Recently, a link between gravitational tension (GT) and energy density via the Kretschmann scalar (KS) was proposed to construct regular black holes (RBHs) in pure Lovelock (PL) gravity. However, including a negative cosmological constant in PL gravity leads to a curvature singularity. Here, we choose the coupling constants such that the Lovelock equations admit an n-fold degenerate AdS vacuum (LnFDGS), allowing us to construct an RBH with $\Lambda <0$, where the energy density is analogous to the previously mentioned model. To achieve this, we propose alternative definitions for both the KS and GT. We find that, for mass parameter values greater than the extremal value $M_{\min }$, our RBH solution becomes indistinguishable from the AdS vacuum black hole from inside the event horizon out to infinity. At small scales, quantum effects modify the geometry and thermodynamics, removing the singularity. Furthermore, due to the lack of analytical relationships between the event horizon, photon sphere, and shadow in LnFDGS, we propose a numerical method to represent these quantities. Full article

Multispectral LiDAR (MSL) systems offer a significant advantage by actively capturing both spatial and spectral information. These systems offer significant promise in supporting the comprehensive analysis and precise classification of underwater targets. In this study, we build an MSL system based on an acousto-optic tunable filter (AOTF) to investigate the feasibility of underwater sphere classification. The MSL prototype features a spectral resolution of 20 nm and 13 spectral channels, covering a range from 560 to 800 nm. Laboratory-based experiments were conducted to evaluate the accuracy of range measurements and the classification performance of the system. The spectral curves of nine distinct spheres acquired by the MSL were utilized for classification using a support vector machine (SVM). The experimental results indicate that classification using multispectral data yields a higher accuracy and Kappa coefficient. Finally, the point cloud acquired from scanning experiments further validated the MSL system’s performance. This finding preliminarily validates the feasibility of multispectral LiDAR for classifying submerged spherical targets. Full article

Precise estimate of antenna location is essential for high-quality three-dimensional (3D) radar imaging, especially under sparse sampling schemes. In scenarios involving synchronized scanning and rotational motion, small deviations in the radar’s transmitting position can lead to significant phase errors, thereby degrading image fidelity or even causing image failure. To address this challenge, we propose a novel trajectory estimation method based on microwave three-point ranging. The method utilizes three fixed microwave-reflective calibration spheres positioned outside the imaging scene. By measuring the one-dimensional radial distances between the radar and each of the three spheres, and geometrically constructing three intersecting spheres in space, the radar’s spatial position can be uniquely determined at each sampling moment. This external reference-based localization scheme significantly reduces positioning errors without requiring precise synchronization control between scanning and rotation. Furthermore, the proposed approach enhances the robustness and flexibility of sparse sampling strategies in near-field radar imaging. Beyond ground-based setups, the method also holds promise for drone-borne 3D imaging applications, enabling accurate localization of onboard radar systems during flight. Simulation results and error analysis demonstrate that the proposed method improves trajectory accuracy and supports high-fidelity 3D reconstruction under non-ideal sampling conditions. Full article