Search Results (13)

Multispectral imaging can provide objective quantitative data on various clinical pathologies, e.g., abnormal content of bio-substances in human skin. Performance of diagnostics increases with decreased spectral bandwidths of imaging; from this point, ultra-narrowband laser spectral line imaging is well suited for diagnostic applications. In this study, 40 volunteers participated in clinical validation tests of a newly developed prototype device for triple laser line whole-body skin imaging. The device comprised a vertically movable high-resolution camera coupled with a specific illumination unit—a side-emitting optical fiber spiral that emits simultaneously three RGB laser spectral lines at the wavelengths 450 nm, 520 nm, and 628 nm. The prototype’s design details, skin spectral image processing, and the obtained first clinical data are reported and discussed. Full article

Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer therapy that uses NIR light and conjugates of a tumor-targeting monoclonal antibody and phthalocyanine dye. In clinical practice, frontal and cylindrical diffusers are the only options for NIR illumination. However, illumination in a narrow space is technically difficult with such diffusers. Therefore, we evaluated a lateral illumination system using a lateral emitting laser (LEL) fiber. The LEL fiber illuminated a certain area in a lateral direction. NIR-PIT with an LEL fiber reduced luciferase activity in a light-dose-dependent manner in A431-GFP-luc cells in vitro and significantly suppressed tumor proliferation in a xenograft mouse model. To evaluate the usefulness of the LEL fiber in the illumination of a narrow space, a tumor was illuminated from the inside of a cylinder, mimicking a narrow space, and the fluorescence intensity in the tumor was monitored. In the frontal diffuser, NIR light was unevenly delivered and little light reached a distal tumor area from the illuminated side. By contrast, the LEL fiber allowed a uniform illumination of the entire tumor, and a loss of fluorescence was observed even in distal areas. These findings suggested that the LEL fiber can be used for NIR-PIT and is suitable for NIR light illumination in a narrow space. Full article

The advent of fiber optic technology in geophysics exploration has grown in its use in the exploration, production, and monitoring of subsurface environments, revolutionizing the way data are gathered and interpreted critically to speed up decision-making and reduce expense and time. Distributed Acoustic Sensing (DAS) has been increasingly utilized to build relationships in complex geophysics environments by utilizing continuous measurement along fiber optic cables with high spatial resolution and a frequency response of up to 10 KHz. DAS, as fiber optic technology examining backscattered light from a laser emitted inside the fiber and measuring strain changes, enables the performance of subsurface imaging in terms of real-time monitoring for Vertical Seismic Profiling (VSP), reservoir monitoring, and microseismic event detection. This review examines the most widely used fiber optic cables employed for DAS acquisition, namely Single-Mode Fiber (SMF) and Multi-Mode Fiber (MMF), with the different deployments and scopes of data used in geophysics exploration. Over the years, SMF has emerged as a preferred type of fiber optic cable utilized for DAS acquisition and, in most applications examined in this review, outperformed MMF. On the other side, MMF has proven to be preferable when used to measure distributed temperature. Finally, the fiber optic cable deployment technique and acquisition parameters constitute a pivotal preliminary step in DAS data preprocessing, offering a pathway to improve imaging resolution based on DAS measurement as a future scope of work. Full article

Air-coupled ultrasound sensors have advantages over contact ultrasound sensors when a sample should not become contaminated or influenced by the couplant or the measurement has to be a fast and automated inline process. Thereby, air-coupled transducers must emit high-energy pulses due to the low air-to-solid power transmission ratios (10⁻³ to 10⁻⁸). Currently used resonant transducers trade bandwidth—a prerequisite for material parameter analysis—against pulse energy. Here we show that a combination of a non-resonant ultrasound emitter and a non-resonant detector enables the generation and detection of pulses that are both high in amplitude (130 dB) and bandwidth (2 µs pulse width). We further show an initial application: the detection of reflections inside of a carbon fiber reinforced plastic plate with thicknesses between 1.7 mm and 10 mm. As the sensors work contact-free, the time of flight and the period of the in-plate reflections are independent parameters. Hence, a variation of ultrasound velocity is distinguishable from a variation of plate thickness and both properties are determined simultaneously. The sensor combination is likely to find numerous industrial applications necessitating high automation capacity and opens possibilities for air-coupled, single-side ultrasonic inspection. Full article

A McKibben artificial muscle is a typical soft actuator, and it features flexibility, lightweight, and low cost. It consists of a rubber tube and a sleeve which is woven with spiral fibers, and contracts axially by applying pneumatic pressure to the rubber tube. We have developed the combination structure of the McKibben artificial muscle and the optical fiber which works as a contractile displacement sensor. The optical fiber can be braided into the sleeve which is the necessary component of the artificial muscle, which means that the optical fiber works as not only the sensor element but also the actuator element. In the previous sensor system, the light-receiving part (photo IC diode) and the light-emitting part (LED) were located at the base and tip sides of the artificial muscle, respectively. This configuration has a limitation in applications and the possibility of electrical line troubles. In this report, the LED and the photo IC diode are arranged at the base end of the artificial muscle by improving the fabrication process. Through the process, the optical fiber from the base can be returned to the base again via the tip, and the LED and photo IC diode can be located at the base side of the artificial muscle. Experimentally, the relation between the sensor output and contractile displacement of the artificial muscle was confirmed. Full article

Bicomponent photoluminescent polymer optical fibers (PL-POFs) have been melt-spun and in-situ drawn to different extents. The results suggest that scattering in the sheath can effectively increase the photoluminescent dye excitation probability in the fiber core. The core/sheath PL-POFs are made of a semi-crystalline fluoropolymer sheath of low refractive index (RI) and an amorphous cycloolefin polymeric core of high RI, which is doped with a luminescent dye. The axial light emission, as well as the guiding attenuation coefficients of the core/sheath PL-POFs, have been measured using a side-illumination set-up. The incident blue laser is down-converted to red light, which is re-emitted and partially guided by the core. The axial light emission is measured at the fiber tip as a function of the distance from the illumination position to the integrating sphere. It is demonstrated that the presence of a semi-crystalline sheath significantly enhances the axial light emission and that it also lowers the attenuation coefficient, compared to the emission and guiding properties of PL core-only fibers. Additionally, the attenuation coefficient has been found to be lower in more strongly drawn PL-POFs. Wide-angle X-ray diffraction and small-angle X-ray scattering experiments reveal structural differences in differently drawn PL-POFs that can be linked to the observed differences in the optical properties. Full article

An overview of the most important methods for producing side-emitting polymer optical fibers is given. Based on a systematic literature and patent search, the methods that are applied in practice and explored in research are identified. The fabrication methods are classified into four groups according to the physical phenomenon that hinders total internal reflection: bulk scattering, bending, surface perforations and luminescence. Subdivisions are made regarding the actual processing steps. The production methods are described in detail and discussed with respect to their customizability and applications. Full article

E-textiles represent an emerging technology aiming toward the development of fabric with augmented functionalities, enabling the integration of displays, sensors, and other electronic components into textiles. Healthcare, protective clothing, fashion, and sports are a few examples application areas of e-textiles. Light-emitting textiles can have different applications: sensing, fashion, visual communication, light therapy, etc. Light emission can be integrated with textiles in different ways: fabricating light-emitting fibers and planar light-emitting textiles or employing side-emitting polymer optical fibers (POFs) coupled with light-emitting diodes (LEDs). Different kinds of technology have been investigated: alternating current electroluminescent devices (ACELs), inorganic and organic LEDs, and light-emitting electrochemical cells (LECs). The different device working principles and architectures are discussed in this review, highlighting the most relevant aspects and the possible approaches for their integration with textiles. Regarding POFs, the methodology to obtain side emissions and the critical aspects for their integration into textiles are discussed in this review. The main applications of light-emitting fabrics are illustrated, demonstrating that LEDs, alone or coupled with POFs, represent the most robust technology. On the other hand, OLEDs (Organic LEDs) are very promising for the future of light-emitting fabrics, but some issues still need to be addressed. Full article

Polymer optical fibers (POFs) were used for preparing side-emitting polymer optical fibers (SPOFs), which were processed with acetone and n-hexane combined in selected proportions by a solvent treatment method. The effects of the volume ratio of acetone to n-hexane and treatment time on response variable factors were investigated. The center composite design (CCD) based response surface methodology (RSM), a quadratic model, and a two-factor interaction model were developed to relate the preparation variables of illumination intensity, breaking strength, and rigidity. According to analysis of variance (ANOVA), the factors affecting the optimization of each response factor were determined. The predicted values after process optimization were found to be highly similar to the experimental values. The optimal conditions for the preparation of SPOF were as follows: the volume ratio of acetone to hexane was 1.703, and the treatment time was 2.716 s. The three response variables of SPOF prepared under the optimal conditions were: illumination intensity 19.339 mV, breaking strength 5.707 N, and rigidity 572.013 N·mm². Full article

Proper ventilation of a patient with an endotracheal tube (ETT) requires proper placement of the ETT. We present a sensitive, noninvasive, operator-free, and cost-effective optical sensor, called Opt-ETT, for the real-time assessment of ETT placement and alerting of the clinical care team should the ETT become displaced. The Opt-ETT uses a side-firing optical fiber, a near-infrared light-emitting diode, two photodetectors with an integrated amplifier, an Arduino board, and a computer loaded with a custom LabVIEW program to monitor the position of the endotracheal tube inside the windpipe. The Opt-ETT generates a visual and audible warning if the tube moves over a distance set by the operator. Displacement prediction is made using a second-order polynomial fit to the voltages measured from each detector. The system is tested on ex vivo porcine tissues, and the accuracy is determined to be better than 1.0 mm. In vivo experiments with a pig are conducted to test the performance and usability of the system. Full article

Saliva has gained considerable attention as a diagnostics alternative to blood analyses. A wide spectrum of salivary compounds is correlated to blood concentrations of biomarkers, providing informative and discriminative data regarding the state of health. Intra-oral detection and assessment of food and beverage intake can be correlated and provides valuable information to forecast the formation and modification of salivary biomarkers. In this context, the present work proposes a novel intra-oral optical fiber sensor, developed around an optical coupler topology, and exemplified on the detection and assessment of wine intake, which is accounted for example for the formation of N^ε-carboxymethyllysine Advanced Glycation End-products. A laboratory proof of concept validates the proposed solution on four white and four red wine samples. The novel optical sensor geometry shows good spectral properties, accounting for selectivity with respect to grape-based soft drinks. This enables intra-oral detection and objective quality assessment of wine. Moreover, its implementation exploits the advantages of fiber-optics sensing and facilitates integration into a mouthguard, holding considerable potential for real-time biomedical applications to investigate Advanced Glycation End-products in the saliva and their connection with consumption of wine, for the evaluation of risk factors in diet-related diseases. Full article

This paper presents the development of a smart carpet based on polymer optical fiber (POF) for ground reaction force (GRF) and spatio-temporal gait parameter assessment. The proposed carpet has 20 intensity variation-based sensors on one fiber with two photodetectors for acquisition, each one for the response of 10 closer sensors. The used multiplexing technique is based on side-coupling between the light sources and POF lateral sections in which one light-emitting diode (LED) is activated at a time, sequentially. Three tests were performed, two for sensor characterization and one for validation of the smart carpet, where the first test consisted of the application of calibrated weights on the top of each sensor for force characterization. In the second test, the foot was positioned on predefined points distributed on the carpet, where a mean relative error of 2.9% was obtained. Results of the walking tests on the proposed POF-embedded smart carpet showed the possibility of estimating the GRF and spatio-temporal gait parameters (step and stride lengths, cadence, and stance duration). The obtained results make possible the identification of gait events (stance and swing phases) as well as the stance duration and double support periods. The proposed carpet is a low-cost and reliable tool for gait analysis in different applications. Full article

Directly modulated long-wavelength vertical cavity surface emitting lasers (VCSELs) are considered for the implementation of sliceable bandwidth/bitrate variable transceivers for very high capacity transmission (higher than 50 Gb/s per wavelength) in metropolitan area systems characterized by reduced cost, power consumption, and footprint. The impact of the frequency chirp measured for InP VCSELs with different kinds of design (high-bandwidth very short cavity and widely-tunable with micro electro-mechanical systems (MEMS) top mirror) is analyzed in case of discrete multitone (DMT) direct modulation in combination with 25-GHz wavelength selective switch (WSS) filtering. The maximum transmitted capacity for both dual side- and single side-band DMT modulation is evaluated as a function of the number of crossed nodes in a mesh metro network, comparing VCSEL based transmitters performance also with the case of external electro-absorption modulator use. Finally, the maximum reach achieved based on the received optical signal to noise ratio (OSNR) and the fiber span length is discussed. The results confirm the possibility to use directly-modulated long-wavelength VCSELs for the realization of sliceable bandwidth/bitrate variable transmitters targeting 50-Gb/s capacity per polarization, also in the presence of 5 crossed WSSs for reaches of hundreds of kilometers in multi-span Erbium-doped fiber amplified (EDFA) metro links supported by coherent detection. Full article