Search Results (20)

Carryover slag (COS) entrained from the basic oxygen furnace (BOF) during tapping is highly oxidizing and affects secondary steelmaking by increasing deoxidizer consumption, refractory wear, P reversion, and decreasing steel cleanliness. A kinetic COS amount estimation model was developed by using the effective equilibrium reaction zone (EERZ) method. The amount of COS was determined by iteratively adjusting the carryover slag coefficient (CSC) until predicted steel and slag compositions approached industrial measurements. Validation with four industrial heats confirmed that the model effectively predicts COS under both complete and incomplete deoxidation conditions. Further simulation results show that increasing the CSC from 2 to 4 kg per tonne of steel leads to 9.3 ppm P reversion. The calculations also confirmed that larger COS amounts accelerate refractory wear due to the higher input of readily reducible components, particularly FeO and MnO. Full article

Plants defend against pathogens such as fungi by initiating coordinated structural and chemical responses. Pathogen perception triggers rapid cytosolic calcium influx and calcium oscillations that drive defense gene expression, yet the mechanisms by which these signals encode stressor intensity and propagate systematically remain unclear. Here, we present a microfluidic system to characterize intracellular calcium dynamics in protonemal colonies of the moss Physcomitrium patens (Hedw.) upon precise and reversible exposure to fungal chitin oligosaccharides. Epifluorescent imaging of cells expressing the calcium indicator GCaMP6f revealed a rapid, coordinated calcium response to chitin addition, followed by stereotyped oscillations that subsided quickly upon stimulus removal. We implemented an unbiased image segmentation algorithm using pixel-based k-means clustering to automatically locate regions with specific oscillatory signatures. Calcium dynamics were distinct across adjacent cells, distinguishable by cell type, and significantly modulated by circadian rhythm, adaptation time within the device, and stimulus timing. Cytosolic calcium oscillations, which rose and fell symmetrically within about 60 s, occurred spontaneously during the subjective night and following short adaptation periods. Chitin elicited strong oscillations with increased frequency, amplitude, and duration, and repeated pulses entrained regular, colony-wide oscillations at the stimulation interval. This study complements prior investigations of whole plant and growth tip dynamics and provides a quantitative framework to study calcium signaling in plants, including mechanisms of signal propagation and the role of oscillation frequency on gene expression. Full article

As the fundamental unit of soil structure, soil aggregates play a crucial role in enhancing soil carbon and nitrogen storage, thereby supporting soil fertility and overall health, particularly in fragile karst regions. This study aims to quantify the effects of various ecological construction measures on soil aggregate stability, including focusing on geometric mean diameter (GMD), mean weight diameter (MWD), and K values, as well as aggregate-related organic carbon (SOC) and total nitrogen (TN), soil mechanical composition, and aggregate content. The ecological construction measures examined include plantation forests (Y7th–rgl), restored forests (Y6th–zr), fruit forests (Y6th–jgl), and contour reverse slope terraces (Y1th–crt). Compared to sloping farmland, contour reverse slope terraces, with their distinctive priority induction function, significantly increased the content of medium-fine particle aggregates, greater than 87%. Among the ecological construction measures, plantation forests exhibited the highest aggregate stability, with an average increase ranging from 8% to 157%. Notably, microaggregates, regardless of size, possessed the highest carbon and nitrogen contents, contributing significantly to soil carbon and nitrogen pools. Furthermore, both plantation and contour reverse slope terrace treatments demonstrated an equal contribution of carbon and nitrogen across all aggregate sizes. The partial least squares path modeling (PLS-PM) analysis indicates that land use type and the content of carbon and nitrogen pools are the primary factors influencing soil aggregate stability. These findings suggest that plantations are particularly effective in enhancing soil and water conservation in fragile karst areas, while the contour reverse slope terrace method shows potential for stabilizing soil structure over extended time scales due to its unique “preferential entrainment” function. Full article

Understanding the flow instabilities encountered by the turbocharger compressor is an important step toward improving its overall design for performance and efficiency. While an experimental study using Particle Image Velocimetry was previously conducted to examine the flow field at the inlet of the turbocharger compressor, the present work complements that effort by analyzing the flow structures leading to stall instability within the same impeller. Experimentally validated three-dimensional computational fluid dynamics predictions are carried out at three discrete mass flow rates, including 77 g/s (stable, maximum flow condition), 57 g/s (near peak efficiency), and 30 g/s (with strong reverse flow from the impeller) at a fixed rotational speed of 80,000 rpm. Large stationary stall cells were observed deep within the impeller at 30 g/s, occupying a significant portion of the blade passage near the shroud between the suction surface of the main blades and the pressure surface of the splitter blades. These stall cells are mainly created when a substantial portion of the inlet core flow is unable to follow the impeller’s axial to radial bend against the adverse pressure gradient and becomes entrained by the reverse flow and the tip leakage flow, giving rise to a region of low-momentum fluid in its wake. This phenomenon was observed to a lesser extent at 57 g/s and was completely absent at 77 g/s. On the other hand, the inducer rotating stall was found to be most dominant at 57 g/s. The entrainment of the tip leakage flow by the core flow moving into the impeller, leading to the generation of an unstable, wavy shear layer at the inducer plane, was instrumental in the generation of rotating stall. The present analyses provide a detailed characterization of both stationary and rotating stall cells and demonstrate the physics behind their formation, as well as their effect on compressor efficiency. The study also characterizes the entropy generation within the impeller under different operating conditions. While at 77 g/s, the entropy generation is mostly concentrated near the shroud of the impeller with the core flow being almost isentropic, at 30 g/s, there is a significant increase in the area within the blade passage that shows elevated entropy production. The tip leakage flow, its interaction with the blades and the core forward flow, and the reverse flow within the impeller are found to be the major sources of irreversibilities. Full article

The selection of entrainers primarily focuses on their ability to alter the relative volatility. However, the impact of feed composition on entrainer selection has often been overlooked. In this study, we conducted two case analyses of the minimum azeotropic mixtures in the ethyl acetate–ethanol and acetone–methanol systems to explore how the feed composition influences the entrainer selection when aiming for maximum economic efficiency. Additionally, the impact of the entrainer type (positive or reverse) on the economic benefits was also investigated. The cases revealed that economic benefits will be notably enhanced when the selected entrainer preferentially targets and removes the low-content component as the light key component. For the two cases studied, when the feed composition was 0.2–0.8, compared to preferentially separating the high-content component, preferentially separating the lower-content component resulted in a reduction in energy consumption by more than 24.14% and 22.72%, respectively. The results show that the ideal entrainer should be capable of converting the higher-content component in the feed into the heavy key component. Full article

A linear system identification technique has been widely used to track neural entrainment in response to continuous speech stimuli. Although the approach of the standard regularization method using ridge regression provides a straightforward solution to estimate and interpret neural responses to continuous speech stimuli, inconsistent results and costly computational processes can arise due to the need for parameter tuning. We developed a novel approach to the system identification method called the detrended cross-correlation function, which aims to map stimulus features to neural responses using the reverse correlation and derivative of convolution. This non-parametric (i.e., no need for parametric tuning) approach can maintain consistent results. Moreover, it provides a computationally efficient training process compared to the conventional method of ridge regression. The detrended cross-correlation function correctly captures the temporal response function to speech envelope and the spectral–temporal receptive field to speech spectrogram in univariate and multivariate forward models, respectively. The suggested model also provides more efficient computation compared to the ridge regression to process electroencephalography (EEG) signals. In conclusion, we suggest that the detrended cross-correlation function can be comparably used to investigate continuous speech- (or sound-) evoked EEG signals. Full article

Despite the importance of solid concentration in froth flotation, its effect on flotation kinetics and entrainment has rarely been studied. In this study, the flotation kinetics and entrainment in quartz and hematite single-mineral flotation systems as a function of the solid concentration and particle size were investigated using dodecylamine acetate as a collector. Kinetics modeling showed that the Gamma distribution achieved the best agreement with the experimental data, whereas the Classical and Klimpel models poorly fit the data (e.g., RMSE). The flotation rate constants (k) of both quartz and hematite at a higher solid concentration showed a concave shape, with the inflexion point at the middle-size range, whereas this trend altered at lower solid concentrations. Overall, quartz exhibited higher equilibrium recoveries (R_∞) than hematite, which indicates its better overall rate constants. The degree of water recovery in both the quartz and hematite systems was higher at higher solid concentrations, but the hematite system exhibited higher water R_∞ than the quartz system, meaning that the entrainment of gangue could be higher in direct hematite flotation than the reverse one. Therefore, a higher solid concentration is associated with better overall quartz recovery and can reduce hematite loss by entrainment during reverse flotation. An inverse relationship was identified between the solid concentration and particle size in terms of the ratio of water recovery to the concentrate. In the reverse flotation of iron ore, refraining from achieving equilibrium recovery could help limit entrainment, but this was not necessarily the case in direct flotation. No entrainment model or method other than the Warren and Ross model approximated the overall trends of flotation at the finest size range (−38 µm). However, extending the Warren method to polynomial distribution led to an improved fit with the experimental results. In addition to the solid concentration, particle density and size were revealed to be key to developing new entrainment models. Finally, after the fast recovery period (true flotation) was over, the slow recoveries were mainly driven by the slow-floating water fraction. Full article

Dopamine D4 receptor (D4R) mechanisms are implicated in psychiatric diseases characterized by cognitive deficits, including schizophrenia, ADHD, and autism. The cellular mechanisms are poorly understood, but impaired neuronal synchronization in cortical networks was proposed to contribute to these deficits. In animal experiments, D4R activation was shown to generate aberrant increased gamma oscillations and to reduce performance on cognitive tasks requiring functional prefrontal cortex (PFC) and hippocampus (HPC) networks. While fast oscillations in the gamma range are important for local synchronization within neuronal ensembles, long-range synchronization between distant structures is achieved by slow rhythms in the delta, theta, alpha ranges. The characteristics of slow oscillations vary between structures during cognitive tasks. HPC activity is dominated by theta rhythm, whereas PFC generates unique oscillations in the 2–4 Hz range. In order to investigate the role of D4R on slow rhythms, cortical activity was recorded in rats under urethane anesthesia in which slow oscillations can be elicited in a controlled manner without behavioral confounds, by electrical stimulation of the brainstem reticular formation. The local field potential segments during stimulations were extracted and subjected to fast Fourier transform to obtain power density spectra. The selective D4R agonist A-412997 (5 and 10 mg/kg) and antagonists L-745870 (5 and 10 mg/kg) were injected systemically and the peak power in the two frequency ranges were compared before and after the injection. We found that D4R compounds significantly changed the activity of both HPC and PFC, but the direction of the effect was opposite in the two structures. D4R agonist enhanced PFC slow rhythm (delta, 2–4 Hz) and suppressed HPC theta, whereas the antagonist had an opposite effect. Analogous changes of the two slow rhythms were also found in the thalamic nucleus reuniens, which has connections to both forebrain structures. Slow oscillations play a key role in interregional cortical coupling; delta and theta oscillations were shown in particular, to entrain neuronal firing and to modulate gamma activity in interconnected forebrain structures with a relative HPC theta dominance over PFC. Thus, the results of this study indicate that D4R activation may introduce an abnormal bias in the bidirectional PFC–HPC coupling which can be reversed by D4R antagonists. Full article

Twelve years of remotely sensed all-sat merged chlorophyll-a concentration unveils strong signatures of chlorophyll-a blooms along the south Java coast. An unprecedented three-times increase in chlorophyll-a concentration is significantly observed along the south Java coast during the southeast monsoon (June–October) than the northwest monsoon (December–April). The multiple regression analysis of dynamic factors evidently indicates that seasonal upwelling is predominantly controlled by the seasonally evolving coastal eddies associated with the seasonally reversing south Java coastal currents (SJCC) and Ekman mass transport (EMT), followed by the relative roles of sea surface temperature (SST) and wind stress curl. The eddy-induced upwelling and EMT-induced coastal upwelling lead to chlorophyll-a blooms during southeast monsoon, well-supported by the entrainment of cold and saline waters (thermocline doming) with low spiciness. On the other hand, the coastal eddies associated with SJCC and SST anomalies play a significant role in modulating the interannual surface chlorophyll-a variability in the domain. Intense chlorophyll-a blooms are observed during the positive IOD years, whereas the least chlorophyll-a concentration is observed during the negative IOD years. The unprecedentedly least chlorophyll-a concentrations during 2010 and 2016 are attributed to the intense and prolonged surface marine heatwaves. Full article

Domains rich in different blend components phase-separate during deposition, creating a film morphology that determines the performance of active layers in organic electronics. However, morphological control either relies on additional fabrication steps or is limited to a small region where an external interaction is applied. Here, we show that different semiconductor-insulator polymer composites can be rapidly dip-coated with the film structure electrically switched between distinct morphologies during deposition guided by the meniscus formed between the stationary barrier and horizontally drawn solid substrate. Reversible and repeatable changes between the morphologies used in devices, e.g., lateral morphologies and stratified layers of semiconductors and insulators, or between phase-inverted droplet-like structures are manifested only for one polarity of the voltage applied across the meniscus as a rectangular pulse. This phenomenon points to a novel mechanism, related to voltage-induced doping and the doping-dependent solubility of the conjugated polymer, equivalent to an increased semiconductor content that controls the composite morphologies. This is effective only for the positively polarized substrate rather than the barrier, as the former entrains the nearby lower part of the coating solution that forms the final composite film. The mechanism, applied to the pristine semiconductor solution, results in an increased semiconductor deposition and 40-times higher film conductance. Full article

Due to its high mechanical penetration rate and lack of pollution of the environment, air reverse circulation drilling is considered to be a promising method for ice drilling. The air reverse circulation is caused by the combination of the ejector and the flushing nozzles in the drill bit. In this paper, CFD software was used to simulate the influence of the structure of the swirler on the effect of air reverse circulation in the swirling drill bit, and a testing stand was established for the testing of air reverse circulation. The results show that for drill bits without flushing nozzles, the smaller the helical angle is, the larger the entrainment ratio will be, meanwhile the smaller the area ratio is, the larger the entrainment ratio will be. In contrast, for drill bits designed with flushing nozzles, the larger the helical angle is, the larger the entrainment ratio will be, and the larger the area ratio is, the larger the entrainment ratio will be. In addition, the presence of the ice core sharply reduces the effect of air reverse circulation. When the ice core’s height exceeds that of the outlet of the swirler, the reverse circulation effect is slightly improved. Full article

The studies of iron (Fe), copper (Cu), and zinc (Zn) isotopic compositions in seafloor andesites are helpful in understanding the metal stable isotope fractionation during magma evolution. Here, the Fe, Cu, and Zn isotopic compositions of andesites from the Kueishantao hydrothermal field (KHF) off northeastern Taiwan, west Pacific, have been studied. The majority of δ⁵⁶Fe values (+0.02‰ to +0.11‰) in the KHF andesites are consistent with those of MORBs (mid-ocean ridge basalts). This suggests that the Fe in the KHF andesites is mainly from a MORB-type mantle. The Fe-Cu-Zn isotopic compositions (δ⁵⁶Fe +0.22‰, δ⁶⁵Cu +0.16‰ to +0.64‰, and δ⁶⁶Zn +0.29‰ to +0.71‰) of the KHF andesites, which are significantly different from those of the MORBs and the continental crust (CC), have a relatively wide range of Cu and Zn isotopic compositions. This is most likely to be a result of the entrainment of the sedimentary carbonate-derived components into an andesitic magma. The recycled altered rocks (higher δ⁵⁶Fe, lower δ⁶⁶Zn) could preferentially incorporate isotopically light Fe and heavy Zn into the magma, resulting in relative enrichment of the lighter Fe and heavier Zn isotopes in the andesites. The majority of the δ⁵⁶Fe values in the KHF andesites are higher than those of the sediments and the local CC and lower than those of the subducted altered rocks, while the reverse is true for δ⁶⁶Zn, suggesting that the subseafloor sediments and CC materials (lower δ⁵⁶Fe, higher δ⁶⁶Zn) contaminating the rising andesitic magma could preferentially incorporate isotopically heavy Fe and light Zn into the magma, resulting in relative enrichment of the heavier Fe and lighter Zn isotopes in the andesites. Thus, the characteristics of the Fe and Zn isotopes in back-arc and island-arc volcanic rocks may also be influenced by the CC and plate subduction components. Full article

Collophane is difficult to upgrade by reverse flotation of quartz with amine collector alone due to its low grade, complex structure, fine dissemination grain size, etc. This investigation was conducted to explore the synergistic effect of dibutyl phthalate (DBP) as a surfactant with cetyltrimethyl ammonium bromide (CTAB) as the collector on the separation of quartz from collophane by means of micro-flotation tests, surface tension and aggregate size measurements, and froth water mass fraction/recovery characterization. It was found that DBP reduced the surface tension of the reagent solution and enhanced the collision probability between bubbles and quartz particles by increasing the size of aggregates through increased hydrophobic interaction between the quartz particles and DBP droplets. The addition of DBP reduced the entrainment of fine collophane particles as a result of improved defoaming and increased the flotation recovery of quartz without resulting in any flotation of collophane at dosages lower than 200 mg/L. Flotation test results with the binary artificial mineral mixture showed that DBP improved the P₂O₅ recovery, SiO₂ rejection, and P₂O₅ grade by up to 7%, 12%, and 1%, respectively. Full article

Collinear wave-current shear interactions are often assumed to be the same for currents following or opposing the direction of regular wave propagation; with momentum and mass exchanges restricted to the thin oscillating boundary layer (zero-flux condition) and enhanced but equal wave-averaged bed shear stresses. To examine these assumptions, a prototype-scale experiment investigated the nature of turbulent exchanges in flows with currents aligned to, and opposing, wave propagation over a mobile sandy bed. Estimated mean and maximum stresses from measurements above the bed exceeded predictions by models of bed shear stress subscribing to the assumptions above, suggesting the combined boundary layer is larger than predicted by theory. The core flow experiences upward turbulent fluxes in aligned flows, coupled with sediment entrainment by vortex shedding at flow reversal, whilst downward fluxes of eddies generated by the core flow, and strong adverse shear can enhance near-bed mass transport, in opposing currents. Current-aligned coherent structures contribute significantly to the stress and energy dissipation, and display characteristics of wall-attached eddies formed by the pairing of counter-rotating vortices. These preliminary findings suggest a notable difference in wave-following and wave-opposing wave-current interactions, and highlight the need to account for intermittent momentum-exchanges in predicting stress, boundary layer thickness and sediment transport. Full article

Monosialotetrahexosylganglioside (GM1) has good activity on brain diseases and was developed to be a drug applied in clinics for neurological disorders and nerve injury. It is difficult to isolate GM1 in industry scale from the brains directly. In this work, a simple and highly efficient method with high yield was developed for the isolation, conversion, and purification of GM1 from a pig brain. Gangliosides (GLS) were first extracted by supercritical CO₂ (SCE). The optimum extraction time of GLS by SCE was 4 h, and the ratio of entrainer to acetone powder from the pig brain was 3:1 (v/w). GM1 was then prepared from GLS by immobilized sialidase and purified by reverse-phase silica gel. Sodium alginate embedding was used for the immobilization of sialidase. Under the optimized method, the yield of high-purity GM1 was around 0.056%. This method has the potential to be applied in the production of GM1 in the industry. Full article