Search Results (101)

Fungi, from saprophytes to pathogens, face predictable daily fluctuations in light, temperature, humidity, and nutrient availability. To cope, they have evolved an internal circadian clock that confers a major adaptive advantage. This review critically synthesizes current knowledge on the molecular architecture and physiological relevance of fungal circadian systems, moving beyond the canonical Neurospora crassa model to explore the broader phylogenetic diversity of timekeeping mechanisms. We examine the core transcription-translation feedback loop (TTFL) centered on the FREQUENCY/WHITE COLLAR (FRQ/WCC) system and contrast it with divergent and non-canonical oscillators, including the metabolic rhythms of yeasts and the universally conserved peroxiredoxin (PRX) oxidation cycles. A central theme is the clock’s role in gating cellular defenses against oxidative, osmotic, and nutritional stress, enabling fungi to anticipate and withstand environmental insults through proactive regulation. We provide a detailed analysis of chrono-pathogenesis, where the circadian control of virulence factors aligns fungal attacks with windows of host vulnerability, with a focus on experimental evidence from pathogens like Botrytis cinerea, Fusarium oxysporum, and Magnaporthe oryzae. The review explores the downstream pathways—including transcriptional cascades, post-translational modifications, and epigenetic regulation—that translate temporal signals into physiological outputs such as developmental rhythms in conidiation and hyphal branching. Finally, we highlight critical knowledge gaps, particularly in understudied phyla like Basidiomycota, and discuss future research directions. This includes the exploration of novel clock architectures and the emerging, though speculative, hypothesis of “chrono-therapeutics”—interventions designed to disrupt fungal clocks—as a forward-looking concept for managing fungal infections. Full article

Background/Objectives: It is essential to explore and disseminate positive deviance strategies that promote resilience, mindfulness, and well-being beyond stress and burnout reduction strategies for residents and physicians who experience high levels of occupational stress. This scoping review maps studies that investigate positive deviance strategies to enhance the well-being of residents and physicians. Methods: A scoping review was conducted by PRISMA guidelines to identify English-language studies on strategies for physician well-being. PubMed, MEDLINE, Embase, and ERIC were searched using terms related to well-being, coping, and medical education. Results: Among the 38 studies included, 17 (44.7%) targeted physicians in graduate medical education (GME), while 19 (50%) focused on continuing medical education (CME). Positive deviance strategies were identified in 26 studies and were most frequently implemented at the microsystem level, such as small group interventions (e.g., coaching, mentoring, and workshops). These strategies addressed individual and organisational factors that contribute to physician well-being and were associated with improvements in life satisfaction, resilience, professional identity, and psychological safety. The review found that positive deviance strategies were often proactive, values-driven, and disseminated organically over time, emphasising the importance of longitudinal engagement and sustained institutional support. Conclusions: This scoping review highlights the growing use of positive deviance strategies, especially at the microsystem level, to promote physician well-being. These approaches emphasise sustainable, values-driven practices and may offer effective, context-sensitive solutions within healthcare systems. Full article

In a highly competitive and high-pressure workplace environment, more and more employees may fall into negative work situations such as work disengagement. The actual effectiveness of avoidant job crafting as a proactive behavior of employees in coping with stress remains controversial, and the positive aspects of its impact are not explored. Based on conservation of resources theory, this study argues that avoidant job crafting mitigates employees’ self-control resource depletion, which in turn effectively helps employees to reduce work disengagement; the above process is moderated by career identity. To test the above hypotheses, this study collects 455 cross-sectional data from Internet companies in various regions of China and uses structural equation modeling to conduct an analysis. The results show the following: avoidant job crafting has a significant negative effect on work disengagement; self-control resource depletion partially mediates the effect of avoidant job crafting on work disengagement; and the negative relationship between avoidant job crafting and self-control resource depletion is stronger when employees’ career identity is higher and vice versa when it is weaker. The above results guide managers to help employees adjust avoidant job crafting correctly and escape negative work situations. Full article

The international construction contracting industry is facing increasingly stringent regulations and complex compliance risks, forcing contractors to reluctantly comply with regulations to cope with external pressure, intense competition, and turbulent markets. The existing research focuses on the passive compliance of contractors and sporadically identifies the driving factors, and lacks a detailed exploration of proactive compliance, which has created a research gap in regard to contractor compliance management, wherein changes to internal passive control and external environmental dynamics cannot be addressed. This study aims to promote proactive compliance by contractors by establishing a theoretical framework, containing factors related to stakeholder pressures, project complexity, and compliance values. This study involves 135 samples of international construction experience, utilizing the partial least squares structural equation modelling (PLS-SEM) technique for data analysis. The findings demonstrate a significant positive impact of stakeholder pressures (β = 0.328, p < 0.01) and compliance values on the promotion of proactive compliance by contractors (β = 0.246, p < 0.01). Moreover, the study reveals that project complexity further strengthens the relationship between stakeholder pressures and proactive compliance (β = 0.203, p < 0.05). By deepening the understanding of the interactions between external pressures, internal control, and proactive compliance in regard to complex project attributes, this study offers a theoretical framework that integrates project level factors and organizational level factors. This study contributes guidance for contractors facing compliance challenges in the global context, enabling them to tackle increasing compliance pressures and risks, thereby facilitating the development of proactive compliance strategies in complex project environments and enhancing their competitiveness and sustainability. Full article

As Artificial Intelligence (AI) has become a crucial element in the competitive advantage of enterprises, it is important to understand how to stimulate employees’ creativity and initiative to cope with AI-driven changes. Drawing from the traditional Chinese wisdom of “remaining vigilant while enjoying prosperity” and based on the Conservation of Resources Theory, this study explored the impact of AI usage on employees’ innovative behavior and proactive skill development. The results of a three-stage survey of 350 questionnaires showed that (1) AI usage positively influences employees’ innovative behavior and proactive skill development; (2) job absorption partially mediates the relationship between AI usage and employees’ innovative behavior; (3) AI job replacement anxiety partially mediates the relationship between AI usage and proactive skill development; and (4) employees’ learning goal orientation positively moderates the impact of AI usage on innovative behavior through job absorption and on proactive skill development through AI job replacement anxiety. This study provides insights into how individuals respond to AI-driven changes and offers a novel perspective for developing research on AI usage at the individual level. Full article

In recent years, changing working conditions have placed high demands on employees, resulting in increased work intensity, which may affect employees’ health and performance. Based on job and personal resources, individual behaviors help to cope with increased work intensity. We investigated two individual behaviors, namely resilient behavior, which is a reactive approach that helps to cope with adverse situations at work, and job crafting, which is a proactive approach to managing the constellation of job demands and job resources. In a study of 1108 employees, we used regression analyses to examine the interplay between work intensity and individual behaviors and their impact on various outcomes. Our results showed that resilient behavior moderated the relationship between work intensity and psychosomatic complaints. In addition, work intensity moderated the relationship between job crafting and task performance. In summary, individual behaviors can have different effects on the constellation of work intensity and specific outcomes. Our findings on the specific effects of resilient behavior and job crafting allow for a more targeted application. Since the above behaviors can be enhanced through training, organizations can embrace this idea to maintain employees’ health and performance. Full article

The COVID-19 pandemic has significantly impacted and disrupted higher education worldwide, creating unprecedented challenges for university students. In New Zealand, universities operated under varying pandemic restrictions, requiring students to frequently transition between online and in-person learning. This distinctive context provides a valuable opportunity to examine students’ academic stress and coping strategies during these transitions. Grounded in the transactional model of Stress–Appraisal–Coping, this research investigates sources of academic stress, coping strategies, and their effectiveness among university students during the pandemic. A mixed-methods approach was employed, with 193 university students completing an online survey incorporating qualitative and quantitative components. The thematic analysis results indicate eight major sources of academic-related stress and three types of coping strategies. Hierarchical regression analysis revealed that proactive and assistance-seeking strategies were associated with effective stress management, while avoidant strategies were linked to poorer outcomes. However, the study is limited by a low response rate (39.68%), which may affect the generalisability of findings. The results underscore the importance of fostering adaptive coping mechanisms in university settings and highlight the need for targeted institutional support to enhance student wellbeing and resilience in the post-pandemic academic landscape. Full article

Objectives: Germline genetic testing is increasingly being integrated into pediatric oncology and a large number of families are interested. Current research on the psychological impact of germline genetic testing is limited by a main focus on individual outcomes in parents or children and little is known about its impact at the family level. Our study addresses that limitation by exploring parents’ lived experiences of how their family—as a whole—is affected by germline genetic testing for cancer predisposition. Methods: In six families who opted for germline genetic testing in the context of cancer predisposition, both parents of six ill children (five boys) with an average age of 9.67 years (SD = 3.77 years) were interviewed individually (N = 12). Germline genetic testing was performed by exome sequencing followed by analysis of a panel of childhood cancer predisposition genes in pediatric cancer patients and their parents. Their experiences were elicited through semi-structured interviews and the data were analyzed using Multi Family Member Interview Analysis. This qualitative study was conducted at Ghent University Hospital in Belgium. Results: The findings demonstrated that while germline genetic testing was generally viewed as a valuable and straightforward step in the child’s oncology trajectory, parents found it difficult to distinguish its impact from the overwhelming stressors of their child’s cancer diagnosis and treatment. However, parents recognized that the testing also significantly affected various family-level processes. Five main themes were identified: talking about germline genetic testing, being together matters (more), differences in coping with germline genetic testing between partners, feelings of guilt and mutual forgiveness, and concerns about the future health of the family. Conclusions: Given the expanded use of germline genetic testing in pediatric oncology, it is critical for clinicians to address the family-level impacts of germline genetic testing. Although families are affected by these issues, they often do not raise them due to the overwhelming challenges posed by the cancer diagnosis and treatment. Proactively addressing these themes could improve the support provided to families undergoing germline genetic testing for cancer predisposition. Full article

Background: Brucellosis, one of the most common zoonotic diseases globally, is a serious public health problem. The complex and diverse clinical manifestations pose numerous challenges for patients when coping with brucellosis. Scarce studies have been performed in China. Objectives: This study aimed to explore the process of coping with brucellosis and different aspects of the phenomenon from the perspective of patients, and propose a conceptual framework of patients’ processes in coping with brucellosis. Methods: Qualitative study based on constructivist grounded theory methodology using in-depth interviews and focus group discussions. The data analysis included initial coding, focused coding, and theoretical coding using the constant comparative method and memo writing. Results: The conceptual framework of “compelled metamorphosing” was constructed, which conceptualized three primary types of coping strategies: “blind persistence”, “resignation to avoidance”, and “proactive pacing”. Symptoms, financial strain, information cocoon, emotional value, and family responsibility had an important impact on coping strategies and played a significant role in driving their development. Conclusions: This paper provides new insight into patients’ lives and describes the strategies patients use to cope with the challenges and problems caused by brucellosis. Compelled metamorphosing represents a basic psychosocial process. These findings can be used to develop future complex interventions and studies. Full article

With the leapfrog development of information and communication technology and the intensification of external competition among enterprises, after-hours work connectivity through communication devices has become a new norm in the workplace. While it offers certain conveniences, the constant connectivity it entails also imposes significant pressure on employees. How to comprehensively understand and rationally treat after-hours work connectivity has become an issue that organizations need to pay great attention to. Based on conservation of resources theory, this study analyzed 407 questionnaires to explore the “double-edged sword” effect of after-hours work connectivity on employee performance and analyzed the moderating effect of the psychological contract. The results indicate the following: (1) Proactive pathway: after-hours work connectivity promotes employees’ job crafting behaviors toward approach-oriented adjustments, thereby enhancing job performance. (2) Passive pathway: after-hours work connectivity encourages employees’ job crafting behaviors toward avoidance-oriented adjustments, leading to decreased job performance. (3) The psychological contract positively moderates the relationship between after-hours work connectivity and approach-oriented job crafting and negatively moderates the relationship between after-hours work connectivity and avoidance-oriented job crafting, regulating both the positive and negative coping pathways. The research findings contribute to assisting organizations in adopting a dialectical perspective towards and effectively utilizing after-hours work connectivity. This aids in achieving a balance between organizational effectiveness and employee well-being, seeking a mutually beneficial work paradigm, and providing managerial recommendations to promote sustainable organizational development. Full article

Background: There are increasing mental health concerns in the construction industry workforce, with stress being a primary concern. This qualitative study investigates stress experiences and the management of stress in office-based and on-site workers in the UK building construction sector. This study can provide key insights for construction, but also potentially other industries which struggle with high stress levels among their employees. Methods: A total of 40 semi-structured interviews (20 on-site/20 office-based) were conducted at large-scale building construction projects in the southeast UK. Framework method analysis was used to derive an understanding of stress in the workplace and coping strategies. Results: The study identified two major themes: the negative influence of work stress on personal and professional wellbeing, and the management of stress through proactive and reactive coping strategies. Results indicated that on-site workers frequently cited high workloads, tight deadlines, and safety concerns, whereas office-based workers tended to highlight job complexity and organisational pressures. Both population sub-groups reported stress affecting their work performance, with site-workers having the added concern of physical health and safety. Coping strategies among workers tended to rely on support networks, outside-the-workplace hobbies, and boundary-setting, among others. Conclusions: Stress remains a significant problem in the workplace and affects wellbeing; however, there are ways to mitigate the stress. Our findings could provide a foundation for intervention development. Full article

Despite global progress in LGBTQ+ rights, sexual minorities in China face significant societal pressures and legal ambiguities, which remain poorly understood. This study explores the potential mediating role of proactive and preventive coping strategies in the relationship between perceived stress and outness levels among Chinese LGBTQ+ individuals. Survey data from 267 Chinese LGBTQ+ individuals aged 16–42 revealed high levels of perceived stress within this community. Both proactive and preventive coping strategies significantly mediated the negative impact of perceived stress on outness levels. These findings contribute to the understanding of LGBTQ+ community’s perceived stress and outness status in China, highlighting the need for inclusive policies and support systems to improve their mental health and social well-being. Full article

Background: Teaching is a physically and mentally challenging profession that demands high emotional involvement, often leading to stress and anxiety. Understanding how teachers cope with these demands is essential for enhancing their well-being and effectiveness. Objectives: This study aimed to (1) investigate personal and school-based well-being initiatives that teachers use for maintaining their occupational well-being, and (2) develop a coping strategy model that enhances teachers’ occupational well-being. Methods: This study utilised a qualitative phenomenological approach to explore the coping strategies of Australian primary school teachers. Results: The twenty-one participants interviewed employed ten diverse coping strategies classified into five personal and five school-based well-being-enabling initiatives. The personal strategies included setting boundaries, exercise and physical health, social support and interactions, mental health and mindfulness, and work–life balance. The school-based initiatives comprised supportive leadership, colleague support, flexibility and autonomy, resource availability, and proactive approaches to address challenges. A novel SHIELD model incorporating Support, Health, Interaction, Empathy, Leadership, and Development strategies was formulated as a holistic coping strategy for enhancing teachers’ occupational well-being. Conclusions: The findings highlight the necessity of a holistic approach to teacher well-being, integrating both personal and institutional support systems. Schools can enhance teacher well-being by fostering a supportive and empathetic culture, providing necessary resources, and encouraging healthy lifestyles. The SHIELD model offers a comprehensive framework for supporting teachers and improving educational outcomes. Full article

Career crafting offers a new approach for individuals to cope with changing career situations. However, few studies have focused on personality-related antecedents that stably predict career proactivity. Additionally, as individuals’ careers are embedded in various social relationships, career crafting involves significant social interaction. Our study focuses on gratitude, which is related to social interaction, suggesting that gratitude fosters an appreciation for interpersonal relationships, providing a beneficial impetus for career crafting. A quantitative approach was adopted with a three-wave survey with 825 responses, and SPSS 26 and Mplus 8.3 were used as the analytical software for confirmatory factor analysis, hierarchical regression analysis, and path analysis. We conducted an empirical examination employing a moderated mediation model grounded in the framework of proactive motivation. The results revealed a positive correlation between gratitude and career crafting, with prosocial motivation mediating this relationship. Simultaneously, intrinsic motivation moderated the relationship between prosocial motivation and career crafting. Our study emphasizes gratitude’s role in career crafting and explores how it, along with prosocial motivations, drives proactive behaviors, responding to calls for relational work redesign and examining interactions between intrinsic and prosocial motivations in careers. It has important practical implications for individuals, organizations, and career counselors. Full article

Inherited and current trends of urbanization result in growing agri–urban mixed land use patterns that strongly call for innovative management and planning tools at the urban/rural interface. This could especially help to cope with both resilience and environmental fairness goals. In this framework, the category of the Agriculture Park (AP) deserves much attention in relating meaningful experiences, especially in Mediterranean areas. This article deepens the category with the aim of assessing its features as a viable tool in the planning domain to jointly protect and enhance peri-urban farmland areas. In particular, the adopted methodology taps into an integrated and holistic approach to define and assess, by design, a multi-purpose model of a Public Agri–urban Park (PAP) drawing on the Public–Private Partnership (PPP) management model (using break-even analysis to define the contents of the PPP itself), inhabitants’ participation, and referring to a typical fringe area in the municipality of Prato (Italy). Results show the potential of the PAP to jointly achieve—according to a proactive model of green spaces’ protection—many sustainable design targets along with new forms of services aimed at social welfare. At the same time, the article highlights the call for public bodies and agencies to overcome the “business as usual” and “silo-framed” institutional approach and establish fruitful collaborative and synergistic co-design procedures with inhabitants and local stakeholders. Full article