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8,967 Results Found

  • Article
  • Open Access
3 Citations
1,765 Views
13 Pages

12 February 2025

Polysaccharides in plants and microorganisms have important application value, and their purification and preparation is a prerequisite for in-depth research. However, there is currently a lack of dedicated separation and purification instruments for...

  • Review
  • Open Access
66 Citations
7,422 Views
17 Pages

Polysaccharide Structures and Their Hypocholesterolemic Potential

  • Inês M. V. Silva,
  • Fernanda Machado,
  • Maria João Moreno,
  • Cláudia Nunes,
  • Manuel A. Coimbra and
  • Filipe Coreta-Gomes

28 July 2021

Several classes of polysaccharides have been described to have hypocholesterolemic potential, namely cholesterol bioaccessibility and bioavailability. This review will highlight the main mechanisms by which polysaccharides are known to affect cholest...

  • Article
  • Open Access
19 Citations
3,412 Views
20 Pages

Preparation, Characterization, and Bioactivities of Polysaccharide–Nano-Selenium and Selenized Polysaccharides from Acanthopanax senticosus

  • Xiaoli Li,
  • Ying Li,
  • Xueyan Wang,
  • Rui Zhang,
  • Jiaojiao Xue,
  • Yi Ding,
  • Xiuling Chu and
  • Jianqing Su

22 March 2024

Acanthopanax senticosus polysaccharide–nano-selenium (ASPS-SENPS) and A. selenopanax selenized polysaccharides (Se-ASPS) were synthesized, and their characterization and biological properties were compared. The acid extraction method was used t...

  • Review
  • Open Access
54 Citations
9,434 Views
31 Pages

Polysaccharide-Based Transdermal Drug Delivery

  • Jingyuan Li,
  • Hong Xiang,
  • Qian Zhang and
  • Xiaoqing Miao

Materials derived from natural plants and animals have great potential for transdermal drug delivery. Polysaccharides are widely derived from marine, herbal, and microbial sources. Compared with synthetic polymers, polysaccharides have the advantages...

  • Review
  • Open Access
25 Citations
6,911 Views
26 Pages

Sulfation of Various Polysaccharide Structures: Different Methods and Perspectives

  • Yaroslava D. Berezhnaya,
  • Aleksandr S. Kazachenko,
  • Anna S. Kazachenko,
  • Yuriy N. Malyar and
  • Valentina S. Borovkova

29 July 2024

Sulfated polysaccharides have a variety of important biologically active properties, such as anticoagulant, hypolipidemic, antiviral activity, the ability to be a means of targeted drug delivery and to improve the water solubility of certain drugs. I...

  • Article
  • Open Access
2 Citations
5,192 Views
10 Pages

Extended Polysaccharide Analysis within the Liposomal Encapsulation of Polysaccharides System

  • Roozbeh Nayerhoda,
  • Dongwon Park,
  • Charles Jones,
  • Elsa N. Bou Ghanem and
  • Blaine A. Pfeifer

26 July 2020

The Liposomal Encapsulation of Polysaccharides (LEPS) dual antigen vaccine carrier system was assessed across two distinct polysaccharides for encapsulation efficiency, subsequent liposomal surface adornment with protein, adjuvant addition, and size...

  • Review
  • Open Access
208 Citations
14,684 Views
24 Pages

Polysaccharide-Based Micelles for Drug Delivery

  • Nan Zhang,
  • Patricia R. Wardwell and
  • Rebecca A. Bader

Delivery of hydrophobic molecules and proteins has been an issue due to poor bioavailability following administration. Thus, micelle carrier systems are being investigated to improve drug solubility and stability. Due to problems with toxicity and im...

  • Review
  • Open Access
264 Citations
21,219 Views
17 Pages

Polysaccharide-Based Membranes in Food Packaging Applications

  • Ana R. V. Ferreira,
  • Vítor D. Alves and
  • Isabel M. Coelhoso

Plastic packaging is essential nowadays. However, the huge environmental problem caused by landfill disposal of non-biodegradable polymers in the end of life has to be minimized and preferentially eliminated. The solution may rely on the use of biopo...

  • Article
  • Open Access
34 Citations
6,069 Views
10 Pages

Polysaccharide conjugates were alkali-extracted from green tea (TPC-A). Although it contained 11.80% covalently binding proteins, TPC-A could not bind to the Coomassie Brilliant Blue dyes G250 and R250. TPC-A had no expected characteristic absorption...

  • Review
  • Open Access
4 Citations
8,482 Views
19 Pages

Polysaccharide as a Separation Medium for Gel Electrophoresis

  • Tsutomu Arakawa,
  • Masataka Nakagawa,
  • Chiaki Sakuma,
  • Yui Tomioka,
  • Yasunori Kurosawa and
  • Teruo Akuta

Gel electrophoresis and size exclusion chromatography (SEC) are vital techniques in biochemical research, employing gel matrix structures made of polysaccharides or synthetic polymers like polyacrylamide for the analysis and separation of macromolecu...

  • Review
  • Open Access
55 Citations
8,170 Views
17 Pages

6 May 2022

Biocompatible, nontoxic, and biodegradable polysaccharides are considered as a promising base for bio-inspired materials, applicable as scaffolds in regenerative medicine, coatings in drug delivery systems, etc. The tunable macroscopic properties of...

  • Review
  • Open Access
5 Citations
5,743 Views
11 Pages

Didymo and Its Polysaccharide Stalks: Beneficial to the Environment or Not?

  • Hurmat Ejaz,
  • Esther Somanader,
  • Uday Dave,
  • Hermann Ehrlich and
  • M. Azizur Rahman

Didymosphenia geminata diatoms, or Didymo, was first found to be an invasive species that could have negative impacts on the environment due to the aggressive growth of its polysaccharide-based stalks. The stalks’ adhesive properties have prompted pa...

  • Review
  • Open Access
70 Citations
6,321 Views
42 Pages

Polysaccharide-Based Coatings as Drug Delivery Systems

  • Anita Ioana Visan and
  • Rodica Cristescu

Therapeutic polysaccharide-based coatings have recently emerged as versatile strategies to transform a conventional medical implant into a drug delivery system. However, the translation of these polysaccharide-based coatings into the clinic as drug d...

  • Review
  • Open Access
4 Citations
2,072 Views
14 Pages

Membrane processes are extensively employed in a range of industrial and food applications. Due to growing environmental concerns and the introduction of regulatory measures, it is imperative to develop innovative membrane materials that can effectiv...

  • Article
  • Open Access
48 Citations
7,242 Views
14 Pages

Characterization and Antitumor Activity of a Polysaccharide from Sarcodia ceylonensis

  • Yijun Fan,
  • Mengchuan Lin,
  • Aoshuang Luo,
  • Ze Chun and
  • Aoxue Luo

25 July 2014

A water-soluble polysaccharide from Sarcodia ceylonensis was obtained by using the method of water-extraction and ethanol-precipitation. The polysaccharide was further purified by chromatography on AB-8 and ADS-7 columns, yielding a pure polysacchari...

  • Review
  • Open Access
64 Citations
8,553 Views
29 Pages

Biosourced Polysaccharide-Based Superabsorbents

  • Ludovic Llanes,
  • Pascal Dubessay,
  • Guillaume Pierre,
  • Cédric Delattre and
  • Philippe Michaud

In the last decades, many studies have been conducted on new materials to meet a growing industrial demand and to move scientific research forward. Superabsorbents are good examples of materials that have generated special attention in many fields fo...

  • Review
  • Open Access
33 Citations
10,019 Views
15 Pages

Marine Polysaccharide Networks and Diatoms at the Nanometric Scale

  • Vesna Svetličić,
  • Vera Žutić,
  • Galja Pletikapić and
  • Tea Mišić Radić

9 October 2013

Despite many advances in research on photosynthetic carbon fixation in marine diatoms, the biophysical and biochemical mechanisms of extracellular polysaccharide production remain significant challenges to be resolved at the molecular scale in order...

  • Review
  • Open Access
185 Citations
19,657 Views
28 Pages

Protein–Polysaccharide Composite Materials: Fabrication and Applications

  • Elizabeth J. Bealer,
  • Shola Onissema-Karimu,
  • Ashley Rivera-Galletti,
  • Maura Francis,
  • Jason Wilkowski,
  • David Salas-de la Cruz and
  • Xiao Hu

17 February 2020

Protein–polysaccharide composites have been known to show a wide range of applications in biomedical and green chemical fields. These composites have been fabricated into a variety of forms, such as films, fibers, particles, and gels, dependent...

  • Review
  • Open Access
44 Citations
12,133 Views
16 Pages

3 March 2014

Linear polysaccharides are typically composed of repeating mono- or disaccharide units and are ubiquitous among living organisms. Polysaccharide diversity arises from chain-length variation, branching, and additional modifications. Structural diversi...

  • Review
  • Open Access
122 Citations
13,251 Views
15 Pages

22 May 2018

Polysaccharide hydrogels have been increasingly utilized in various fields. In this review, we focus on polysaccharide-based hydrogels used as probiotic delivery systems. Probiotics are microorganisms with a positive influence on our health that live...

  • Article
  • Open Access
17 Citations
4,270 Views
14 Pages

Preparation and Characterization of Polysaccharide-Based Hydrogels for Cutaneous Wound Healing

  • Hongyan Xue,
  • Meng Sun,
  • Xiaoliang Zhao,
  • Yonggang Wang,
  • Jinxin Yan and
  • Weijie Zhang

22 April 2022

Natural hydrogels are growing in interest as a priority for wound healing. Plant polysaccharides have a variety of biological pharmacological activities, and chitosan hydrogels have proven strong antimicrobial effects, but hydrogels prepared with pol...

  • Review
  • Open Access
231 Citations
15,981 Views
37 Pages

Review on the Production of Polysaccharide Aerogel Particles

  • Kathirvel Ganesan,
  • Tatiana Budtova,
  • Lorenz Ratke,
  • Pavel Gurikov,
  • Victor Baudron,
  • Imke Preibisch,
  • Philipp Niemeyer,
  • Irina Smirnova and
  • Barbara Milow

31 October 2018

A detailed study of the production of polysaccharide aerogel (bio-aerogel) particles from lab to pilot scale is surveyed in this article. An introduction to various droplets techniques available in the market is given and compared with the lab scale...

  • Article
  • Open Access
57 Citations
6,357 Views
18 Pages

The Antidiabetic Effect of Grape Pomace Polysaccharide-Polyphenol Complexes

  • Filipa Campos,
  • Andreia F. Peixoto,
  • Pedro A. R. Fernandes,
  • Manuel A. Coimbra,
  • Nuno Mateus,
  • Victor de Freitas,
  • Iva Fernandes and
  • Ana Fernandes

15 December 2021

Type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic metabolic diseases of the 21st century. Nevertheless, its prevalence might be attenuated by taking advantage of bioactive compounds commonly found in fruits and vegetables. This wor...

  • Review
  • Open Access
90 Citations
7,706 Views
23 Pages

The Microfluidic Technique and the Manufacturing of Polysaccharide Nanoparticles

  • Enrica Chiesa,
  • Rossella Dorati,
  • Silvia Pisani,
  • Bice Conti,
  • Gloria Bergamini,
  • Tiziana Modena and
  • Ida Genta

The microfluidic technique has emerged as a promising tool to accelerate the clinical translation of nanoparticles, and its application affects several aspects, such as the production of nanoparticles and the in vitro characterization in the microenv...

  • Communication
  • Open Access
8 Citations
2,726 Views
8 Pages

1 December 2022

In this study, we developed a method to fabricate chitosan-based network polysaccharides via the condensation between amino groups in water-soluble chitosan (WSCS) and a carboxylate-terminated maltooligosaccharide crosslinker. We previously reported...

  • Review
  • Open Access
169 Citations
14,674 Views
33 Pages

8 December 2017

Polysaccharides are natural biopolymers that have been recognized to be the most promising hosts for the synthesis of metallic nanoparticles (MNPs) because of their outstanding biocompatible and biodegradable properties. Polysaccharides are diverse i...

  • Review
  • Open Access
20 Citations
4,299 Views
25 Pages

Research Progress on Emerging Polysaccharide Materials Applied in Tissue Engineering

  • Chunyu Su,
  • Yutong Chen,
  • Shujing Tian,
  • Chunxiu Lu and
  • Qizhuang Lv

11 August 2022

The development and application of polysaccharide materials are popular areas of research. Emerging polysaccharide materials have been widely used in tissue engineering fields such as in skin trauma, bone defects, cartilage repair and arthritis due t...

  • Review
  • Open Access
136 Citations
17,214 Views
41 Pages

Comprehensive Review of Polysaccharide-Based Materials in Edible Packaging: A Sustainable Approach

  • Yuan Zhao,
  • Bo Li,
  • Cuicui Li,
  • Yangfan Xu,
  • Yi Luo,
  • Dongwu Liang and
  • Chongxing Huang

10 August 2021

Edible packaging is a sustainable product and technology that uses one kind of “food” (an edible material) to package another kind of food (a packaged product), and organically integrates food with packaging through ingenious material design. Polysac...

  • Article
  • Open Access
15 Citations
4,174 Views
13 Pages

8 June 2021

Polysaccharide conjugates are important renewable materials. If properly designed, they may for example be able to carry drugs, be proactive (e.g., with amino acid substituents) and can carry a charge. These aspects can be particularly useful for bio...

  • Article
  • Open Access
1 Citations
1,754 Views
12 Pages

Screening of Lentinula edodes Strains for High Polysaccharide Production and In Vitro Antioxidant Activities

  • Jie Zhang,
  • Kanwal Rida,
  • Jiahao Wen,
  • Xiumei Yu,
  • Yunfu Gu,
  • Maoqiang He,
  • Qiang Chen and
  • Quanju Xiang

30 April 2025

Lentinan is one of the main metabolites of Lentinula edodes and exhibits numerous biological properties, such as antitumor and antioxidant activity. Despite recent advancements, its commercialization remains constrained by a lengthy cultivation cycle...

  • Review
  • Open Access
16 Citations
5,137 Views
29 Pages

The Beneficial Role of Polysaccharide Hydrocolloids in Meat Products: A Review

  • Hanxiao Bao,
  • Yuxi Wang,
  • Yue Huang,
  • Yuhao Zhang and
  • Hongjie Dai

10 January 2025

Polysaccharide hydrocolloids have garnered increasing attention from consumers, experts, and food processing industries due to their advantages of abundant resources, favorable thickening properties, emulsification stability, biocompatibility, biodeg...

  • Review
  • Open Access
80 Citations
4,270 Views
19 Pages

Polysaccharide-Based Nanomedicines Targeting Lung Cancer

  • Asif Ahmad Bhat,
  • Gaurav Gupta,
  • Khalid Saad Alharbi,
  • Obaid Afzal,
  • Abdulmalik S. A. Altamimi,
  • Waleed Hassan Almalki,
  • Imran Kazmi,
  • Fahad A. Al-Abbasi,
  • Sami I. Alzarea and
  • Kamal Dua
  • + 4 authors

A primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe. Radiation treatment, surgery, and chemotherapy ar...

  • Review
  • Open Access
11 Citations
3,670 Views
14 Pages

Advances in Polysaccharide Production Based on the Co-Culture of Microbes

  • Wanrong Peng,
  • Xueying Guo,
  • Xinyi Xu,
  • Dan Zou,
  • Hang Zou and
  • Xingyong Yang

28 June 2023

Microbial polysaccharides are natural carbohydrates that can confer adhesion capacity to cells and protect them from harsh environments. Due to their various physiological activities, these macromolecules are widely used in food, medicine, environmen...

  • Review
  • Open Access
251 Citations
8,990 Views
22 Pages

Natural Polysaccharide Nanomaterials: An Overview of Their Immunological Properties

  • Fernando G. Torres,
  • Omar P. Troncoso,
  • Anissa Pisani,
  • Francesca Gatto and
  • Giuseppe Bardi

14 October 2019

Natural occurring polymers, or biopolymers, represent a huge part of our planet biomass. They are formed by long chains of monomers of the same type or a combination of different ones. Polysaccharides are biopolymers characterized by complex secondar...

  • Article
  • Open Access
3 Citations
3,097 Views
12 Pages

Identification and Quantification of a Pneumococcal Cell Wall Polysaccharide by Antibody-Enhanced Chromatography Assay

  • James Z. Deng,
  • Zhifeng Chen,
  • James Small,
  • Yue Yuan,
  • Kara Cox,
  • Aimin Tang,
  • Jeanette Roman,
  • Liming Guan,
  • Katrina Feller and
  • Kalpit Vora
  • + 1 author

28 April 2024

Multivalent pneumococcal vaccines have been developed successfully to combat invasive pneumococcal diseases (IPD) and reduce the associated healthcare burden. These vaccines employ pneumococcal capsular polysaccharides (PnPs), either conjugated or un...

  • Review
  • Open Access
19 Citations
3,715 Views
31 Pages

Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery

  • Ming Song,
  • Adila Aipire,
  • Elzira Dilxat,
  • Jianmin Li,
  • Guoyu Xia,
  • Ziwen Jiang,
  • Zhongxiong Fan and
  • Jinyao Li

Clinical drug administration aims to deliver drugs efficiently and safely to target tissues, organs, and cells, with the objective of enabling their therapeutic effects. Currently, the main approach to enhance a drug’s effectiveness is ensuring...

  • Article
  • Open Access
16 Citations
5,461 Views
12 Pages

Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation

  • Zhi-Peng Li,
  • Hong-Bing Liu,
  • Quan-Wei Zhang,
  • Li-Feng Li,
  • Wan-Rong Bao,
  • Dik-Lung Ma,
  • Chung-Hang Leung,
  • Zhao-Xiang Bian,
  • Ai-Ping Lu and
  • Quan-Bin Han

Polysaccharides, which exert immunoregulatory effects, are becoming more and more popular as food supplements; however, certain components of ordinary foods could be reducing the polysaccharides beneficial effects. Quercetin, a flavonoid found in com...

  • Feature Paper
  • Review
  • Open Access
300 Citations
21,279 Views
35 Pages

Prospect of Polysaccharide-Based Materials as Advanced Food Packaging

  • Aleksandra Nešić,
  • Gustavo Cabrera-Barjas,
  • Suzana Dimitrijević-Branković,
  • Sladjana Davidović,
  • Neda Radovanović and
  • Cédric Delattre

29 December 2019

The use of polysaccharide-based materials presents an eco-friendly technological solution, by reducing dependence on fossil resources while reducing a product’s carbon footprint, when compared to conventional plastic packaging materials. This r...

  • Article
  • Open Access
6 Citations
2,967 Views
11 Pages

Physicochemical and Microstructural Characteristics of Sulfated Polysaccharide from Marine Microalga

  • Diana Fimbres-Olivarria,
  • Jorge Marquez-Escalante,
  • Karla G. Martínez-Robinson,
  • Valeria Miranda-Arizmendi,
  • Yubia De Anda-Flores,
  • Agustín Rascon-Chu,
  • Francisco Brown-Bojorquez and
  • Elizabeth Carvajal-Millan

5 December 2023

Marine algae are a valuable source of polysaccharides. However, the information available on sulfated polysaccharides from microalgae is limited. Navicula sp. is a microalga present in the Sea of Cortez, of which little is known regarding their polys...

  • Article
  • Open Access
14 Citations
5,897 Views
12 Pages

13 February 2020

Biomaterials made of natural polysaccharides have attracted much attention due to the fact of their excellent properties, such as high biocompatibility and biodegradability, and their specific biological functions based on their chemical structures....

  • Review
  • Open Access
56 Citations
9,793 Views
18 Pages

Mushroom Polysaccharide-Assisted Anticarcinogenic Mycotherapy: Reviewing Its Clinical Trials

  • Iyyakkannu Sivanesan,
  • Manikandan Muthu,
  • Judy Gopal and
  • Jae-Wook Oh

25 June 2022

Of the biologically active components, polysaccharides play a crucial role of high medical and pharmaceutical significance. Mushrooms have existed for a long time, dating back to the time of the Ancient Egypt and continue to be well explored globally...

  • Article
  • Open Access
37 Citations
7,305 Views
13 Pages

Anti-Tumor Activity of a Polysaccharide from Blueberry

  • Xiyun Sun,
  • Ning Liu,
  • Zhaoxia Wu,
  • Ying Feng and
  • Xianjun Meng

27 February 2015

Blueberries (Vaccinium spp.) are rich in bioactive compounds. However, the biological activity of polysaccharides from blueberry has not been reported so far. This study evaluated the anti-tumor and immunological activities of a polysaccharide (BBP3-...

  • Review
  • Open Access
26 Citations
16,855 Views
25 Pages

Polysaccharide Vaccines: A Perspective on Non-Typhoidal Salmonella

  • Sumudu R. Perera,
  • Akosiererem S. Sokaribo and
  • Aaron P. White

Polysaccharides are often the most abundant antigens found on the extracellular surfaces of bacterial cells. These polysaccharides play key roles in interactions with the outside world, and for many bacterial pathogens, they represent what is present...

  • Review
  • Open Access
111 Citations
17,464 Views
49 Pages

A Comprehensive Review of Polysaccharide-Based Hydrogels as Promising Biomaterials

  • Achraf Berradi,
  • Faissal Aziz,
  • Mounir El Achaby,
  • Naaila Ouazzani and
  • Laila Mandi

30 June 2023

Polysaccharides have emerged as a promising material for hydrogel preparation due to their biocompatibility, biodegradability, and low cost. This review focuses on polysaccharide-based hydrogels’ synthesis, characterization, and applications. T...

  • Review
  • Open Access
36 Citations
5,652 Views
12 Pages

PUL-Mediated Plant Cell Wall Polysaccharide Utilization in the Gut Bacteroidetes

  • Zhenzhen Hao,
  • Xiaolu Wang,
  • Haomeng Yang,
  • Tao Tu,
  • Jie Zhang,
  • Huiying Luo,
  • Huoqing Huang and
  • Xiaoyun Su

Plant cell wall polysaccharides (PCWP) are abundantly present in the food of humans and feed of livestock. Mammalians by themselves cannot degrade PCWP but rather depend on microbes resident in the gut intestine for deconstruction. The dominant Bacte...

  • Review
  • Open Access
13 Citations
5,499 Views
12 Pages

This review examines the immobilization of A. pullulans cells for production of the fungal polysaccharide pullulan. Pullulan is a water-soluble gum that exists structurally as a glucan consisting primarily of maltotriose units, which has a variety of...

  • Review
  • Open Access
28 Citations
6,539 Views
40 Pages

Insights on Some Polysaccharide Gel Type Materials and Their Structural Peculiarities

  • Ioana Alexandra Duceac,
  • Magdalena-Cristina Stanciu,
  • Marioara Nechifor,
  • Fulga Tanasă and
  • Carmen-Alice Teacă

26 November 2022

Global resources have to be used in responsible ways to ensure the world’s future need for advanced materials. Ecologically friendly functional materials based on biopolymers can be successfully obtained from renewable resources, and the most p...

  • Review
  • Open Access
25 Citations
6,515 Views
13 Pages

11 February 2019

Bacterial pathogens expressing capsular polysaccharides are common causes of mucosal infections (pneumonia, intestinal), as well as often fatal, invasive infections (meningitis, bloodstream infections) in children and adults worldwide. These chemical...

  • Article
  • Open Access
20 Citations
4,089 Views
11 Pages

Purification, Characterization, and Self-Assembly of the Polysaccharide from Allium schoenoprasum

  • Fengrui Zhang,
  • Jun Zheng,
  • Zeyu Li,
  • Zixuan Cai,
  • Fengqiao Wang and
  • Dong Yang

11 June 2021

The major polysaccharide component from the stalk of Allium schoenoprasum (AssP) was extracted and purified. Gel filtration chromatography purified AssP exhibited a molecular weight of around 1.7 kDa, which was verified by MALDI-ToF-MS. The monosacch...

  • Review
  • Open Access
4 Citations
2,627 Views
22 Pages

Recent Advances in Polysaccharide-Based Hydrogels for Tumor Immunotherapy

  • Youxi Zhou,
  • Kaizhao Chen,
  • Hongwei Cheng and
  • Shuaishuai Zhang

20 February 2025

Immunotherapy has revolutionized cancer treatment and led to a significant increase in patient survival rates and quality of life. However, the effectiveness of current immunotherapies is limited by various factors, including immune evasion mechanism...

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