Search Results (172)

Several attempts have been made to replace the critical raw material platinum (Pt) with other metals, mainly focusing on its functional performance, while safety and sustainability criteria are often overlooked. Here, the substitution of Pt by nickel-based coatings is addressed for water electrolysis applications. Risk assessment and life cycle assessment are iteratively performed at the laboratory scale and after upscaling metal coating protocols. The challenges for the transition towards an integrated safe and sustainable by design (SSbD) approach are identified, and strategies are proposed to resolve them. Valuable insights emerge from the individual assessments (e.g., hotspots, trade-offs, and recommendations for sustainability and safety), as well as regarding the transition towards an integrated SSbD (e.g., dealing with data gaps and uncertainties). Full article

The slurry aluminizing process is widely employed to enhance the oxidation and corrosion resistance of nickel-based superalloys used in high-temperature environments such as gas turbines and aerospace engines. This study investigates the effects of the concentration of Al vapors in the reactor chamber and the initial slurry layer thickness on the microstructure, chemical composition, and phase composition of aluminide coatings. Coatings were manufactured on Ni-based superalloy substrates using CrAl powders as an aluminum source and chloride- and fluoride-based activator salts. The effect of the initial thickness of the slurry layer was studied by varying the amount of deposited slurry in terms of mg_slurry/cm²_sample (with constant mg_slurry/cm³_chamber). The microstructure and phase composition of the produced aluminide coatings were evaluated by SEM, EDS, and XRD analysis. Slurry thickness can affect concentration gradients during diffusion, and the best results were obtained with an initial slurry amount of 100 mg_slurry/cm²_sample. The effect of the Al vapor phase in the reaction chamber was then investigated by varying the mg_slurry/cm³_chamber ratio while keeping the slurry layer thickness constant at 100 mg_slurry/cm²_sample. This parameter influences the amount of Al at the substrate surface before the onset of solid-state diffusion, and the best results were obtained for a 6.50 mg_slurry/cm³_chamber ratio with the formation of 80 µm coatings (excluding the interdiffusion zone) with a β-NiAl phase throughout the thickness. To validate process flexibility, the same parameters were successfully applied to produce platinum-modified aluminides with a bi-phasic ζ-PtAl2 and β-(Ni,Pt)Al microstructure. Full article

Copper is essential for various biological functions, but elevated levels in water can pose serious health risks. In this work, we introduce a novel electrochemical sensor designed for the highly sensitive and selective detection of copper ions. The sensor is based on a screen-printed platinum working electrode coated with a solid-state Nafion layer. Compared to previous platinum-based sensors, this design demonstrates enhanced sensitivity, a wide linear detection range (1 µM to 10 mM), and an exceptionally low limit of detection (1 nM). It also offers a rapid response time of 3–6 s, strong selectivity, and excellent stability. Interference from common metal ions such as Cr²⁺, Zn²⁺, Mn²⁺, Pb²⁺, and Fe²⁺ was minimal, with signal deviations remaining below 2%, and performance remained consistent across varying anion concentrations, showing less than 1% deviation. The use of Nafion as a solid-state electrolyte successfully overcomes challenges typically associated with traditional silver-based reference electrodes. These characteristics make the sensor a reliable and practical tool for the rapid, on-site monitoring of water quality. Full article

This study presents the optimization of a laser ablation process designed to achieve the precise removal of polyamide coatings from ultra-thin platinum wires. Removing polymer coatings is a critical challenge in high-reliability manufacturing processes such as aerospace thermocouple fabrication. The ablation process must not only ensure the complete removal of the polyamide insulation but also maintain the tensile strength of the wire to withstand mechanical handling in subsequent manufacturing stages. Additionally, the exposed platinum surface must exhibit low surface roughness to enable effective soldering and be free of thermal damage or residual debris to pass strict visual inspections. The wires have a total diameter of 65 µm, consisting of a 50 µm platinum core encased in a 15 µm polyamide coating. By utilizing a UV laser with a wavelength of 355 nm, average power of 3 W, a repetition rate range of 20 to 200 kHz, and a high-speed marking system, the process parameters were systematically refined. Initial attempts to perform the ablation in an air medium were unsuccessful due to inadequate thermal control and incomplete removal of the polyamide coating. Hence, a water-assisted ablation technique was explored to address these limitations. Experimental results demonstrated that a scanning speed of 1200 mm/s, coupled with a line spacing of 1 µm and a single ablation pass, resulted in complete coating removal while ensuring the integrity of the platinum substrate. The incorporation of a water layer above the ablation region was considered crucial for effective heat dissipation, preventing substrate overheating and ensuring uniform ablation. The laser’s spot diameter of 20 µm in air and a focal length of 130 mm introduced challenges related to overlap control between successive passes, requiring precise calibration to maintain consistency in coating removal. This research demonstrates the feasibility and reliability of water-assisted laser ablation as a method for a high-precision, non-contact coating material. Full article

The recycling of proton exchange membrane water electrolyzer (PEMWE) raw materials is imperative due to their scarcity, cost, complexity and environmental impact. This is particularly true in the context of expanding electrolyzer manufacturing and reducing production costs. Developing comprehensive recycling strategies requires the creation of a model stack due to the diversity in stack design, structure and materials. The review-derived model presented here provides a sound basis and summarizes the variety of approaches found in the literature and industry. The holistically developed recycling chain, including dismantling, mechanical processing, hydrometallurgical processes and carbon reuse, is characterized by the complete recycling of materials, the reduced application of energy-intensive process steps and the avoidance of environmentally harmful processes. Emphasis is placed on demonstrating the non-destructive disassembly of joined components, the dry mechanical decoating of catalyst-coated membranes, membrane dissolution, the separation of anode and cathode particles and the environmentally friendly hydrometallurgical processing of platinum. Full article

Platinum wires, known for their excellent electrical conductivity and durability, are widely used in high-precision industries, such as aerospace and automotive. These wires are typically coated with polyamide for protection; however, specific manufacturing processes require the coating to be selectively removed. Although traditional chemical stripping methods are effective, they are associated with high costs, safety concerns, and long processing times. As a result, laser ablation has emerged as a more efficient, precise, and cleaner alternative, especially at the microscale. In this study, ultraviolet nanosecond laser ablation was applied to remove polyamide coatings from ultra-thin platinum wires in a water-assisted environment. The presence of water enhances the process by promoting thermal management and minimizing debris. Key processing parameters, including the scanning speed, overlap percentage, and line distance, were evaluated. The optimal result was achieved at a scanning speed of 1200 mm/s, line distance of 1 µm, and single loop in water-ambient, where coating removal was complete, surface roughness remained low, and wire tensile strength was preserved. This performance is attributed to the effective energy distribution across the wire surface and reduced thermal damage due to the heat dissipation role of water, along with controlled overlap that ensured full coverage without overexposure. A thin, well-maintained water layer confined above the apex of the wire played a crucial role in regulating the thermal flow during ablation. This setup helped shield the delicate platinum substrate from overheating, thereby maintaining its mechanical integrity and preventing substrate damage throughout the process. This study primarily focused on analyzing the main effects and two-factor interactions of these parameters using Analysis of Variance (ANOVA). Interactions such as Speed × Overlap and Speed × Line Distance were statistically examined to identify the influence of combined factors on tensile strength and surface roughness. In the second phase of experimentation, the parameter space was further expanded by increasing the line distance and number of loops to reduce the overlap in the X-direction. This allowed for a more comprehensive process evaluation. Again, conditions around 1200 mm/s and 1500 mm/s with 2 µm line distance and two loops offered favorable outcomes, although 1200 mm/s was selected as the optimal speed due to better consistency. These findings contribute to the development of a robust, high-precision laser processing method for ultra-thin wire applications. The statistical insights gained through ANOVA offer a data-driven framework for optimizing future laser ablation processes. Full article

Bioelectronic medicines record biological signals and provide electrical stimulation for the treatment of diseases. Advanced bioelectronic therapies require the development of electrodes that match the softness of the implanted tissues, as the present metal electrodes do not meet this condition. The objective of the present work was to investigate whether the electroconductive polymer polypyrrole (PPy) could be used for fabricating such electrodes, as PPy is several orders softer than metals. For this purpose, we here investigated if electrodes made using coatings and films of PPy doped with naphthalin-2-sulfonic acid (PPy/N) are capable to record and elicit by stimulation cardiac monophasic action potentials (MAPs) and if PPy/N is also biocompatible. The results of this study showed that the tested PPy/N electrodes are capable of recording MAPs almost identical to the MAPs recorded with platinum electrodes and eliciting stimulation-evoked MAPs almost identical to the spontaneous MAPs. In addition, we show here that the cell cultures that we used for biocompatibility tests grew in a similar manner on PPy/N and platinum substrates. We, therefore, conclude that PPy/N coatings and films have recording and electrical stimulation capabilities that are similar to those of platinum electrodes and that PPy/N substrates are as biocompatible as the platinum substrates. Full article

This study utilized tetramethylammonium hydroxide (TMAH) as a substitute for traditional catalysts and successfully incorporated platinum octaethylporphyrin (PtOEP) into SiO₂ nanoparticles (PtOEP@SiO₂) via the Stöber method. Methyl silicone resin was employed as the matrix material, and a drop-coating technique was applied to fabricate thin films of PtOEP@SiO₂ particles for dissolved oxygen (DO) sensing in seawater. By optimizing the concentrations of TMAH and PtOEP, a highly sensitive oxygen-sensing film with a quenching ratio (I₀/I₁₀₀) of 28 was ultimately developed, with a wide linear detection range (0~20 mg/L, R² = 0.994). Stability tests revealed no significant performance degradation during five oxygen–nitrogen cycle tests. After 30 days of immersion in East China Sea seawater, the quenching ratio decreased by only 6%, confirming its long-term stability and excellent resistance to ion interference. This research provides a novel strategy for developing highly reliable in situ marine DO sensors. Full article

We developed a novel biodegradable poly(lactic-co-glycolic acid) (PLGA) polymer chemically modified with paclitaxel (PTX) to form a PLGA-PTX hybrid. Pre-modification of PTX enhanced its loading in PLGA-PTX nanoparticles (NPs). Background/Objectives: PTX is one of the most effective chemotherapy agents used in cancer therapy. The primary mode of PTX’s action is the hyperstabilization of microtubules leading to cell growth arrest. Although highly potent, the drug is water insoluble and requires the Cremophor EL excipient. The toxic effects of the free drug (e.g., neurotoxicity) as well as its solubilizing agent are well established. Thus, there is strong clinical rationale and need for exploring alternative PTX delivery approaches, retaining biological activity and minimizing systemic effects. Methods: The PTX modification method features reacting the C-2′ and C-7 residues with a linker (succinic anhydride) to produce easily accessible carboxyl groups on the PTX for enhanced coupling to the hydroxyl group of PLGA. The PLGA-PTX hybrid, formed via esterification reaction, was used to formulate lipid-coated PLGA-PTX NPs. As proof of concept, the PLGA-PTX NPs were tested in ovarian cancer (OvCA) models, including several patient-derived cell lines (PDCLs), one of which was generated from a platinum-resistant patient. Results: The PLGA-PTX NPs critically remained stable in water and serum while enabling slow drug release. Importantly, PLGA-PTX NPs demonstrated biological activity. Conclusions: We suggest that this approach offers both a new and effective PTX formulation and a possible path towards the development of a new generation of OvCA treatment. Full article

The aim of this study was to produce a coating for protective glass glued to touch displays with high antibacterial effectiveness. This paper presents the structural, mechanical, optical, and antibacterial properties of a TiO₂:Ag–Pt coating prepared by dual reactive DC and RF magnetron sputtering. Characterization techniques used include XRD, TEM with EDS, SEM, AFM, nanoindentation for hardness and Young’s modulus, wettability tests, and optical property analysis. The coating exhibited columnar crystals with a width of 30–50 nm. Crystals of anatase, rutile, silver, and platinum with a size of up to 3 nm were identified. The coating deposited on glass had a concentration of 5.0 ± 0.2% at. Ag and 4.4 ± 0.1% at. Pt. The value of the optical band gap energy, corresponding to the direct transition, was 3.36 eV, while Urbach’s energy was in the order of 500 meV. The hydrophilic coating had a roughness RMS = 1.8 ± 0.2 nm, hardness HV = 6.8 ± 0.5 GPa, and Young’s modulus E = 116 ± 8 GPa. A unique combination of the phase composition of the TiO₂:Ag–Pt coating, metallic Ag and Pt nanoparticles in a ceramic matrix of anatase and rutile crystallites resulted a >90% reduction of Staphylococcus aureus bacteria. This antibacterial effect was attributed to the activation of the doped semiconductor under visible light via plasmon resonance of the Ag and Pt nanoparticles, as well as a light-independent antibacterial action due to Ag⁺ ion release. In contrast, commercial antibacterial coatings typically achieve only around 60% bacterial reduction. Full article

Bacterial infections are the primary cause of mastitis in dairy cattle. Fungal mastitis occurs in 1–12% of cases. Antibiotic therapy, the standard treatment for mastitis, has led to antibiotic-resistant bacteria, reducing treatment efficacy and increasing fungal mastitis occurrence. Antibiotics lack biocidal effects on fungi, which often exhibit resistance to antifungal agents. This study evaluated the antifungal properties of nanoparticles (NPs) against Candida albicans, Candida glabrata, Candida parapsilosis, Diutina rugosa var. rugosa, Diutina catenulata, and Diutina rugosa. Tested NPs included gold (AuNPs), silver (AgNPs), copper (CuNPs), iron with hydrophilic carbon coating (FeCNPs) (1.56–25 mg/L), and platinum (PtNPs) (0.625–10 mg/L), along with their complexes. Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) at 0.75–25 mg/L for AuNPs, AgNPs, CuNPs, and FeCNPs and 0.313–10 mg/L for PtNPs, as well as fungal sensitivity to standard antifungals, were determined. Each strain showed different sensitivities depending on the NPs used and their concentrations. C. glabrata was the most resistant to nanoparticles, while D. catenulata was the most susceptible. PtNPs and FeCNPs showed no or weak biocidal properties. Some mycotic-resistant strains were sensitive to nanoparticles. This study indicates a high in vitro antifungal potential for the application of nanoparticles, especially AgCuNPs, as a new effective non-antibiotic agent for the prevention and control of mycotic mastitis in dairy cattle. Full article

Gold nanostars (AuNSTs) stabilized with adenosine monophosphate (AMP) were synthesized using a scalable method, achieving a 30-fold yield increase compared to previous studies using AMP as a shaping agent, while also reducing the reaction time to 3 h. The AuNSTs were coated with mesoporous silica (mSiO₂) via a robust approach, producing the AuNSTs@mSiO₂ nanoparticles (NPs) with tunable thicknesses and consistent optical properties for a range of morphologies. The NPs were additionally coated with platinum (Pt) before synthesizing the mSiO₂ layer, facilitating a comparative analysis of catalytic activity. The catalytic performance of the bare AuNSTs, the AuNSTs@mSiO₂, and the AuNSTs@Pt@mSiO₂ was evaluated through methylene blue reduction, confirming the gold core as the primary catalytic source. The AuNSTs@Pt@mSiO₂ exhibited enhanced activity, highlighting the potential of the mSiO₂ coatings. Additionally, solid-phase catalytic tests using 3,3′,5,5′-tetramethylbenzidine (TMB) on cellulose discs demonstrated the effectiveness of these NPs under diverse conditions. These findings showcase the versatility and broad catalytic potential of silica-coated NPs for solution- and solid-phase applications. Full article

International projects study the safety aspects of the storage and long-distance transportation of liquid hydrogen at large scales. Catalytic recombiners, which are today key elements of hydrogen risk mitigation in nuclear power plants, could become an efficient safety device to prevent flammable gas mixtures after liquid hydrogen leakages in closed rooms. This study tackles fundamental questions about the operational behavior of typical recombiner catalysts related to the conditions of the start-up and the termination of the catalytic reaction. For this purpose, small-scale catalyst sheets with coatings containing either platinum or palladium as active materials were exposed to gas mixtures of air and hydrogen of up to 4 vol.% at temperatures between −50 °C and 20 °C. Both platinum and palladium showed variation to performance and had stochastic results. Overall, the initialized platinum catalyst was better than the palladium. The experimental results show that the transfer of the recombiner technology from its current application is not easily possible. Full article

An effective deposition of a cinchonine layer on a platinum metal surface can be easily achieved through the cathodic reduction of a cinchonine hydrochloride methanolic solution at a controlled potential of −220 mV vs. the silver standard electrode (SSE). A coated screen-printed platinum electrode has proven to be suitable for cinchonine determination in water, urine, and serum at µg L⁻¹ concentration levels using differential pulse voltammetry in a phosphate buffer solution (pH 7.0). The limits of detection (LOD) and quantitation (LOQ) were 0.6 µg L⁻¹ and 1.8 µg L⁻¹, respectively. Full article

Nanozymes, exemplified by metal nanoparticles, have shown promise in the fields of biological diagnostics and therapeutics. However, their practical application is often hindered by aggregation or deactivation in complex biological systems. Here, we develop a DNA-engineered nanozyme coating to preserve the peroxidase-like catalytic activity of platinum nanoparticles in complex biological environments. We employed thiol-modified single-stranded DNA to coat the platinum nanoparticles through metal–sulfur interaction. We found that the negatively charged DNA coating prevents the aggregation of platinum nanoparticles in high-salt environments. Moreover, the DNA coating functions as a molecular sieve, inhibiting non-specific protein adsorption while preserving substrate access to the catalytic interface, thus sustaining high peroxidase-like catalytic activity in serum. As a proof of concept, we demonstrate miRNA detection in serum samples with a detection limit of 1 fM. This approach offers a versatile strategy for molecular diagnostics of nanozymes in complex biological environments. Full article