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23 pages, 3512 KB  
Review
Advances in the Application of Fractal Theory to Oil and Gas Resource Assessment
by Baolei Liu, Xueling Zhang, Cunyou Zou, Lingfeng Zhao and Hong He
Fractal Fract. 2025, 9(10), 676; https://doi.org/10.3390/fractalfract9100676 - 20 Oct 2025
Viewed by 281
Abstract
In response to the growing complexity of global exploration targets, traditional Euclidean geometric and linear statistical methods reveal inherent theoretical limitations in characterizing hydrocarbon reservoirs as complex geological bodies that exhibit simultaneous local disorder and global order. Fractal theory, with its core parameter [...] Read more.
In response to the growing complexity of global exploration targets, traditional Euclidean geometric and linear statistical methods reveal inherent theoretical limitations in characterizing hydrocarbon reservoirs as complex geological bodies that exhibit simultaneous local disorder and global order. Fractal theory, with its core parameter systems such as fractal dimension and scaling exponents, provides an innovative mathematical–physics toolkit for quantifying spatial heterogeneity and resolving the multi-scale characteristics of reservoirs. This review systematically consolidates recent advancements in the application of fractal theory to oil and gas resource assessment, with the aim of elucidating its transition from a theoretical concept to a practical tool. We conclusively demonstrate that fractal theory has driven fundamental methodological progress across four critical dimensions: (1) In reservoir classification and evaluation, fractal dimension has emerged as a robust quantitative metric for heterogeneity and facies discrimination. (2) In pore structure characterization, the theory has successfully uncovered structural self-similarity across scales, from nanopores to macroscopic vugs, enabling precise modeling of complex pore networks. (3) In seepage behavior analysis, fractal-based models have significantly enhanced the predictive capacity for non-Darcy flow and preferential migration pathways. (4) In fracture network modeling, fractal geometry is proven pivotal for accurately characterizing the spatial distribution and connectivity of natural fractures. Despite significant progress, current research faces challenges, including insufficient correlation with dynamic geological processes and a scarcity of data for model validation. Future research should focus on the following directions: developing fractal parameter inversion methods integrated with artificial intelligence, constructing dynamic fractal–seepage coupling models based on digital twins, establishing a unified fractal theoretical framework from pore to basin scale, and expanding its application in low-carbon energy fields such as carbon dioxide sequestration and natural gas hydrate development. Through interdisciplinary integration and methodological innovation, fractal theory is expected to advance hydrocarbon resource assessment toward intelligent, precise, and systematic development, providing scientific support for the efficient exploitation of complex reservoirs and the transition to green, low-carbon energy. Full article
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22 pages, 3493 KB  
Article
NeuroFed-LightTCN: Federated Lightweight Temporal Convolutional Networks for Privacy-Preserving Seizure Detection in EEG Data
by Zheng You Lim, Ying Han Pang, Shih Yin Ooi, Wee How Khoh and Yee Jian Chew
Appl. Sci. 2025, 15(17), 9660; https://doi.org/10.3390/app15179660 - 2 Sep 2025
Viewed by 615
Abstract
This study investigates on-edge seizure detection that aims to resolve two major constraints that hold the deployment of deep learning models in clinical settings at present. First, centralized training requires gathering and consolidating data across institutions, which poses a serious issue of privacy. [...] Read more.
This study investigates on-edge seizure detection that aims to resolve two major constraints that hold the deployment of deep learning models in clinical settings at present. First, centralized training requires gathering and consolidating data across institutions, which poses a serious issue of privacy. Second, a high computational overhead inherent in inference imposes a crushing burden on resource-limited edge devices. Hence, we propose NeuroFed-LightTCN, a federated learning (FL) framework, incorporating a lightweight temporal convolutional network (TCN), designed for resource-efficient and privacy-preserving seizure detection. The proposed framework integrates depthwise separable convolutions, grouped with structured pruning to enhance efficiency, scalability, and performance. Furthermore, asynchronous aggregation is employed to mitigate training overhead. Empirical tests demonstrate that the network can be reduced fully to 70% with a 44.9% decrease in parameters (65.4 M down to 34.9 M and an inferencing latency of 56 ms) and still maintain 97.11% accuracy, a metric that outperforms both the non-FL and FL TCN optimizations. Ablation shows that asynchronous aggregation reduces training times by 3.6 to 18%, and pruning sustains performance even at extreme sparsity: an F1-score of 97.17% at a 70% pruning rate. Overall, the proposed NeuroFed-LightTCN addresses the trade-off between computational efficiency and model performance, delivering a viable solution to federated edge-device learning. Through the interaction of federated-optimization-driven approaches and lightweight architectural innovation, scalable and privacy-aware machine learning can be a practical reality, without compromising accuracy, and so its potential utility can be expanded to the real world. Full article
(This article belongs to the Section Computing and Artificial Intelligence)
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29 pages, 1150 KB  
Review
What Helps or Hinders Annual Wellness Visits for Detection and Management of Cognitive Impairment Among Older Adults? A Scoping Review Guided by the Consolidated Framework for Implementation Research
by Udoka Okpalauwaekwe, Hannah Franks, Yong-Fang Kuo, Mukaila A. Raji, Elise Passy and Huey-Ming Tzeng
Nurs. Rep. 2025, 15(8), 295; https://doi.org/10.3390/nursrep15080295 - 12 Aug 2025
Viewed by 970
Abstract
Background: The U.S. Medicare Annual Wellness Visit (AWV) offers a structured opportunity for cognitive screening and personalized prevention planning among older adults. Yet, implementation of AWVs, particularly for individuals with cognitive impairment, remains inconsistent across primary care or other diverse care settings. Methods: [...] Read more.
Background: The U.S. Medicare Annual Wellness Visit (AWV) offers a structured opportunity for cognitive screening and personalized prevention planning among older adults. Yet, implementation of AWVs, particularly for individuals with cognitive impairment, remains inconsistent across primary care or other diverse care settings. Methods: We conducted a scoping review using the Consolidated Framework for Implementation Research (CFIR) to explore multilevel factors influencing the implementation of the Medicare AWV’s cognitive screening component, with a focus on how these processes support the detection and management of cognitive impairment among older adults. We searched four databases and screened peer-reviewed studies published between 2011 and March 2025. Searches were conducted in Ovid MEDLINE, PubMed, EBSCOhost, and CINAHL databases. The initial search was completed on 3 January 2024 and updated monthly through 30 March 2025. All retrieved citations were imported into EndNote 21, where duplicates were removed. We screened titles and abstracts for relevance using the predefined inclusion criteria. Full-text articles were then reviewed and scored as either relevant (1) or not relevant (0). Discrepancies were resolved through consensus discussions. To assess the methodological quality of the included studies, we used the Joanna Briggs Institute critical appraisal tools appropriate to each study design. These tools evaluate rigor, trustworthiness, relevance, and risk of bias. We extracted the following data from each included study: Author(s), year, title, and journal; Study type and design; Data collection methods and setting; Sample size and population characteristics; Outcome measures; Intervention details (AWV delivery context); and Reported facilitators, barriers, and outcomes related to AWV implementation. The first two authors independently coded and synthesized all relevant data using a table created in Microsoft Excel. The CFIR guided our data analysis, thematizing our findings into facilitators and barriers across its five domains, viz: (1) Intervention Characteristics, (2) Outer Setting, (3) Inner Setting, (4) Characteristics of Individuals, and (5) Implementation Process. Results: Among 19 included studies, most used quantitative designs and secondary data. Our CFIR-based synthesis revealed that AWV implementation is shaped by interdependent factors across five domains. Key facilitators included AWV adaptability, Electronic Health Record (EHR) integration, team-based workflows, policy alignment (e.g., Accountable Care Organization participation), and provider confidence. Barriers included vague Centers for Medicare and Medicaid Services (CMS) guidance, limited reimbursement, staffing shortages, workflow misalignment, and provider discomfort with cognitive screening. Implementation strategies were often poorly defined or inconsistently applied. Conclusions: Effective AWV delivery for older adults with cognitive impairment requires more than sound policy and intervention design; it demands organizational readiness, structured implementation, and engaged providers. Tailored training, leadership support, and integrated infrastructure are essential. These insights are relevant not only for U.S. Medicare but also for global efforts to integrate dementia-sensitive care into primary health systems. Our study has a few limitations that should be acknowledged. First, our scoping review synthesized findings predominantly from quantitative studies, with only two mixed-method studies and no studies using strictly qualitative methodologies. Second, few studies disaggregated findings by race, ethnicity, or geography, reducing our ability to assess equity-related outcomes. Moreover, few studies provided sufficient detail on the specific cognitive screening instruments used or on the scope and delivery of educational materials for patients and caregivers, limiting generalizability and implementation insights. Third, grey literature and non-peer-reviewed sources were not included. Fourth, although CFIR provided a comprehensive analytic structure, some studies did not explicitly fit in with our implementation frameworks, which required subjective mapping of findings to CFIR domains and may have introduced classification bias. Additionally, although our review did not quantitatively stratify findings by year, we observed that studies from more recent years were more likely to emphasize implementation facilitators (e.g., use of templates, workflow integration), whereas earlier studies often highlighted systemic barriers such as time constraints and provider unfamiliarity with AWV components. Finally, while our review focused specifically on AWV implementation in the United States, we recognize the value of comparative analysis with international contexts. This work was supported by a grant from the National Institute on Aging, National Institutes of Health (Grant No. 1R01AG083102-01; PIs: Tzeng, Kuo, & Raji). Full article
(This article belongs to the Section Nursing Care for Older People)
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18 pages, 2601 KB  
Article
Refined Consolidation Settlement Calculation Based on the Oedometer Tests for Normally and Overconsolidated Clays
by Nopakun Phonchamni, Thammanun Chatwong, Artit Udomchai, Sivarit Sultornsanee, Niwat Angkawisittpan, Noppadol Sangiamsak and Nopanom Kaewhanam
Appl. Sci. 2025, 15(10), 5777; https://doi.org/10.3390/app15105777 - 21 May 2025
Viewed by 2296
Abstract
This study presents an enhanced analytical approach for one-dimensional consolidation settlement by introducing a revised AJOP (arc joint via optimum parameters) equation assuming creep and strain rate effects can be neglected for both normally and overconsolidated clays. This modified equation integrates both curved [...] Read more.
This study presents an enhanced analytical approach for one-dimensional consolidation settlement by introducing a revised AJOP (arc joint via optimum parameters) equation assuming creep and strain rate effects can be neglected for both normally and overconsolidated clays. This modified equation integrates both curved and linear segments within a unified framework, enhancing accuracy across varying stress levels for normally consolidated clay. Additionally, the revised AJOP function, coupled with newly proposed equations for symmetrical and asymmetrical hysteresis, improves the modeling of overconsolidated clay. The findings from a comparative investigation using benchmark datasets and conventional methods, including the linear function (LF) and the curved function (CF), reveal that the revised AJOP method was found to reduce settlement prediction errors by up to 85% compared to LF method (particularly at shallow layers) and by 10–15% compared to the CF method (particularly at deep layers). The revised AJOP equation effectively resolves this error with a wide range of depths. Furthermore, results highlight the crucial impact of clay layering techniques on consolidation settlement predictions. Non-layered models yield lower settlement estimates compared to multilayer approaches, emphasizing the significance of the proper elogσv relationship and layering techniques in enhancing prediction reliability. Full article
(This article belongs to the Special Issue Geotechnical Engineering: Principles and Applications)
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33 pages, 15492 KB  
Article
Seasonal Bias Correction of Daily Precipitation over France Using a Stitch Model Designed for Robust Representation of Extremes
by Philippe Ear, Elena Di Bernardino, Thomas Laloë, Adrien Lambert and Magali Troin
Atmosphere 2025, 16(4), 480; https://doi.org/10.3390/atmos16040480 - 19 Apr 2025
Viewed by 1452
Abstract
Highly resolved and accurate daily precipitation data are required for impact models to perform adequately and correctly measure the impacts of high-risk events. In order to produce such data, bias correction is often needed. Most of those statistical methods correct the probability distributions [...] Read more.
Highly resolved and accurate daily precipitation data are required for impact models to perform adequately and correctly measure the impacts of high-risk events. In order to produce such data, bias correction is often needed. Most of those statistical methods correct the probability distributions of daily precipitation by modeling them with either empirical or parametric distributions. A recent semi-parametric model based on a penalized Berk–Jones (BJ) statistical test, which allows for automatic and personalized splicing of parametric and non-parametric distributions, has been developed. This method, called the Stitch-BJ model, was found to be able to model daily precipitation correctly and showed interesting potential in a bias correction setting. In the present study, we will consolidate these results by taking into account the seasonal properties of daily precipitation in an out-of-sample context and by considering dry days probabilities in our methodology. We evaluate the performance of the Stitch-BJ method in this seasonal bias correction setting against more classical models such as the Gamma, Exponentiated Weibull (ExpW), Extended Generalized Pareto (EGP) or empirical distributions. Results show that a seasonal separation of data is necessary in order to account for intra-annual non-stationarity. Moreover, the Stitch-BJ distribution was able to consistently perform as well as or better than all the other considered models over the validation set, including the empirical distribution, which is often used due to its robustness. Finally, while methods for correcting dry day probabilities can be easily applied, their relevance can be discussed as temporal and spatial correlations are often neglected. Full article
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19 pages, 1418 KB  
Systematic Review
Short- and Long-Term Chest-CT Findings after Recovery from COVID-19: A Systematic Review and Meta-Analysis
by Mustufa Babar, Hasan Jamil, Neil Mehta, Ahmed Moutwakil and Tim Q. Duong
Diagnostics 2024, 14(6), 621; https://doi.org/10.3390/diagnostics14060621 - 14 Mar 2024
Cited by 20 | Viewed by 6628
Abstract
While ground-glass opacity, consolidation, and fibrosis in the lungs are some of the hallmarks of acute SAR-CoV-2 infection, it remains unclear whether these pulmonary radiological findings would resolve after acute symptoms have subsided. We conducted a systematic review and meta-analysis to evaluate chest [...] Read more.
While ground-glass opacity, consolidation, and fibrosis in the lungs are some of the hallmarks of acute SAR-CoV-2 infection, it remains unclear whether these pulmonary radiological findings would resolve after acute symptoms have subsided. We conducted a systematic review and meta-analysis to evaluate chest computed tomography (CT) abnormalities stratified by COVID-19 disease severity and multiple timepoints post-infection. PubMed/MEDLINE was searched for relevant articles until 23 May 2023. Studies with COVID-19-recovered patients and follow-up chest CT at least 12 months post-infection were included. CT findings were evaluated at short-term (1–6 months) and long-term (12–24 months) follow-ups and by disease severity (severe and non-severe). A generalized linear mixed-effects model with random effects was used to estimate event rates for CT findings. A total of 2517 studies were identified, of which 43 met the inclusion (N = 8858 patients). Fibrotic-like changes had the highest event rate at short-term (0.44 [0.3–0.59]) and long-term (0.38 [0.23–0.56]) follow-ups. A meta-regression showed that over time the event rates decreased for any abnormality (β = −0.137, p = 0.002), ground-glass opacities (β = −0.169, p < 0.001), increased for honeycombing (β = 0.075, p = 0.03), and did not change for fibrotic-like changes, bronchiectasis, reticulation, and interlobular septal thickening (p > 0.05 for all). The severe subgroup had significantly higher rates of any abnormalities (p < 0.001), bronchiectasis (p = 0.02), fibrotic-like changes (p = 0.03), and reticulation (p < 0.001) at long-term follow-ups when compared to the non-severe subgroup. In conclusion, significant CT abnormalities remained up to 2 years post-COVID-19, especially in patients with severe disease. Long-lasting pulmonary abnormalities post-SARS-CoV-2 infection signal a future public health concern, necessitating extended monitoring, rehabilitation, survivor support, vaccination, and ongoing research for targeted therapies. Full article
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42 pages, 5103 KB  
Article
The DEWI High-Level Architecture: Wireless Sensor Networks in Industrial Applications
by Ramiro Sámano-Robles, Tomas Nordström, Kristina Kunert, Salvador Santonja-Climent, Mikko Himanka, Markus Liuska, Michael Karner and Eduardo Tovar
Technologies 2021, 9(4), 99; https://doi.org/10.3390/technologies9040099 - 9 Dec 2021
Cited by 3 | Viewed by 4056
Abstract
This paper presents the High-Level Architecture (HLA) of the European research project DEWI (Dependable Embedded Wireless Infrastructure). The objective of this HLA is to serve as a reference framework for the development of industrial Wireless Sensor and Actuator Networks (WSANs) based on the [...] Read more.
This paper presents the High-Level Architecture (HLA) of the European research project DEWI (Dependable Embedded Wireless Infrastructure). The objective of this HLA is to serve as a reference framework for the development of industrial Wireless Sensor and Actuator Networks (WSANs) based on the concept of the DEWI Bubble. The DEWI Bubble constitutes a set of architecture design rules and recommendations that can be used to integrate legacy industrial sensor networks with a modern, interoperable and flexible IoT (Internet-of-Things) infrastructure. The DEWI Bubble can be regarded as a high-level abstraction of an industrial WSAN with enhanced interoperability (via standardized interfaces), dependability, technology reusability and cross-domain development. The DEWI Bubble aims to resolve the issue on how to integrate commercial WSAN technology to match the dependability, interoperability and high criticality needs of industrial domains. This paper details the criteria used to design the HLA and the organization of the infrastructure internal and external to the DEWI Bubble. The description includes the different perspectives, models, or views of the architecture: the entity model, the layered perspective of the entity model and the functional model. This includes an overview of software and hardware interfaces. The DEWI HLA constitutes an extension of the ISO/IEC 29182 SNRA (Sensor Network Reference Architecture) towards the support of wireless industrial applications in different domains: aeronautics, automotive, railway and building. To improve interoperability with existing approaches, the DEWI HLA also reuses some features from other standardized technologies and architectures. The DEWI HLA and the concept of Bubble allow networks with different industrial sensor technologies to exchange information between them or with external clients via standard interfaces, thus providing consolidated access to sensor information of different industrial domains. This is an important aspect for smart city applications, Big Data, Industry 4.0 and the Internet-of-Things (IoT). The paper includes a non-exhaustive review of the state of the art of the different interfaces, protocols and standards of this architecture. The HLA has also been proposed as the basis of the European projects SCOTT (Secure Connected Trustable Things) for enhanced security and privacy in the IoT and InSecTT (Intelligent Secure Trustable Things) for the convergence of artificial intelligence (AI) and the IoT. Full article
(This article belongs to the Section Information and Communication Technologies)
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22 pages, 23060 KB  
Article
A Spatial-Scale Evaluation of Soil Consolidation Concerning Land Subsidence and Integrated Mechanism Analysis at Macro-, and Micro-Scale: A Case Study in Chongming East Shoal Reclamation Area, Shanghai, China
by Qingbo Yu, Xuexin Yan, Qing Wang, Tianliang Yang, Wenxi Lu, Meng Yao, Jiaqi Dong, Jiewei Zhan, Xinlei Huang, Cencen Niu and Kai Zhou
Remote Sens. 2021, 13(12), 2418; https://doi.org/10.3390/rs13122418 - 21 Jun 2021
Cited by 17 | Viewed by 4380
Abstract
Land reclamation has been increasingly employed in many coastal cities to resolve issues associated with land scarcity and natural hazards. Especially, land subsidence is a non-negligible environmental geological problem in reclamation areas, which is essentially caused by soil consolidation. However, spatial-scale evaluation on [...] Read more.
Land reclamation has been increasingly employed in many coastal cities to resolve issues associated with land scarcity and natural hazards. Especially, land subsidence is a non-negligible environmental geological problem in reclamation areas, which is essentially caused by soil consolidation. However, spatial-scale evaluation on the average degree of consolidation (ADC) of soil layers and the effects of soil consolidation on land subsidence have rarely been reported. This study aims to carry out the integrated analysis on soil consolidation and subsidence mechanism in Chongming East Shoal (CES) reclamation area, Shanghai, at spatial-, macro-, and micro-scale so that appropriate guides can be provided to resist the potential environmental hazards. The interferometric synthetic aperture radar (InSAR) technique was utilized to retrieve the settlement curves of the selected onshore (Ra) and offshore (Rb) areas. Then, the hyperbolic (HP) model and three-point modified exponential (TME) model were combined applied to predict the ultimate settlement and to determine the range of ADC rather than a single pattern. With two boreholes Ba and Bb set within Ra and Rb, conventional tests, MIP test, and SEM test were conducted on the collected undisturbed soil to clarify the geological features of exposed soil layers and the micro-scale pore and structure characteristics of representative compression layer. The preliminary results showed that the ADC in Rb (93.1–94.1%) was considerably higher than that in Ra (60.8–78.7%); the clay layer was distinguished as the representative compression layer; on micro-scale, the poor permeability conditions contributed to the low consolidation efficiency and slight subsidence in Rb, although there was more compression space. During urbanization, the offshore area may suffer from potential subsidence when it is subjected to an increasing ground load, which requires special attention. Full article
(This article belongs to the Special Issue Applications of Remote Sensing in Geological Engineering)
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29 pages, 8344 KB  
Article
New Syntheses, Analytic Spin Hamiltonians, Structural and Computational Characterization for a Series of Tri-, Hexa- and Hepta-Nuclear Copper (II) Complexes with Prototypic Patterns
by Ana Maria Toader, Maria Cristina Buta, Fanica Cimpoesu, Andrei-Iulian Toma, Christina Marie Zalaru, Ludmila Otilia Cinteza and Marilena Ferbinteanu
Chemistry 2021, 3(1), 411-439; https://doi.org/10.3390/chemistry3010031 - 15 Mar 2021
Cited by 5 | Viewed by 3873
Abstract
We present a series of pyrazolato-bridged copper complexes with interesting structures that can be considered prototypic patterns for tri-, hexa- and hepta- nuclear systems. The trinuclear shows an almost regular triangle with a μ3-OH central group. The hexanuclear has identical monomer [...] Read more.
We present a series of pyrazolato-bridged copper complexes with interesting structures that can be considered prototypic patterns for tri-, hexa- and hepta- nuclear systems. The trinuclear shows an almost regular triangle with a μ3-OH central group. The hexanuclear has identical monomer units, the Cu6 system forming a regular hexagon. The heptanuclear can be described as two trinuclear moieties sandwiching a central copper ion via carboxylate bridges. In the heptanuclear system, the pyrazolate bridges are consolidating the triangular faces, which are sketching an elongated trigonal antiprism. The magnetic properties of these systems, dominated by the strong antiferromagnetism along the pyrazolate bridges, were described transparently, outlining the energy levels formulas in terms of Heisenberg exchange parameters J, within the specific topologies. We succeeded in finding a simple Kambe-type resolution of the Heisenberg spin Hamiltonian for the rather complex case of the heptanuclear. In a similar manner, the weak intermolecular coupling of two trimer units (aside from the strong exchange inside triangles) was resolved by closed energy formulas. The hexanuclear can be legitimately proposed as a case of coordination-based aromaticity, since the phenomenology of the six-spins problem resembles the bonding in benzene. The Broken-Symmetry Density Functional Theory (BS-DFT) calculations are non-trivial results, being intrinsically difficult at high nuclearities. Full article
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25 pages, 2432 KB  
Article
Social Life-Cycle Assessment: A Review by Bibliometric Analysis
by Irene Huertas-Valdivia, Anna Maria Ferrari, Davide Settembre-Blundo and Fernando E. García-Muiña
Sustainability 2020, 12(15), 6211; https://doi.org/10.3390/su12156211 - 1 Aug 2020
Cited by 124 | Viewed by 10862
Abstract
This study examined the literature on social life-cycle assessment (S-LCA) published in the last 15 years (2003–2018) using bibliometric methods. Applying scientific mapping and analyzing publication performance, the study describes the structure of and trends in S-LCA publications in terms of related subject [...] Read more.
This study examined the literature on social life-cycle assessment (S-LCA) published in the last 15 years (2003–2018) using bibliometric methods. Applying scientific mapping and analyzing publication performance, the study describes the structure of and trends in S-LCA publications in terms of related subject categories, authors, journals, countries, and highly cited articles. Challenges and research gaps in the S-LCA literature were also explored. The content of related papers published in the ISI Web of Science databases was examined to identify the main themes investigated, evolution of publication activity, and most representative elements. Analyses were conducted with SciMAT software. This tool enables researchers to map research specialties by extracting qualitative information in the specialized literature and representing it using quantitative measures. The results show rapid and exponential growth of the S-LCA research line in the past ten years, with a clear upward trend in related publications (mostly case studies), especially after publication of the UNEP/SETAC Guidelines for Social Life Cycle Assessment of Products in 2009: 66% of all articles published on S-LCA were published during the period 2015–2018, primarily by European authors. The findings also delineate S-LCA as a highly fragmented research field that has been applied to diverse sectors (agriculture, bioenergy, transport, water management, chemical products, electronics, etc.), mainly in non-European countries. Critical questions concerning methods, framework, paradigms, and indicators remain to be resolved. This study provides insight into the publication performance of S-LCA, characterizing its intellectual structure and salient authors and works. In identifying hotspots in the S-LCA research, the study provides a useful state-of-the-art reference guide for academics and reveals critical research gaps and potential research avenues for future studies to advance in consolidating the discipline. Full article
(This article belongs to the Special Issue The Role of Social Life Cycle Assessment in Sustainability)
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18 pages, 5324 KB  
Article
Integral Phylogenomic Approach over Ilex L. Species from Southern South America
by Jimena Cascales, Mariana Bracco, Mariana J. Garberoglio, Lidia Poggio and Alexandra M. Gottlieb
Life 2017, 7(4), 47; https://doi.org/10.3390/life7040047 - 22 Nov 2017
Cited by 18 | Viewed by 5882
Abstract
The use of molecular markers with inadequate variation levels has resulted in poorly resolved phylogenetic relationships within Ilex. Focusing on southern South American and Asian species, we aimed at contributing informative plastid markers. Also, we intended to gain insights into the nature [...] Read more.
The use of molecular markers with inadequate variation levels has resulted in poorly resolved phylogenetic relationships within Ilex. Focusing on southern South American and Asian species, we aimed at contributing informative plastid markers. Also, we intended to gain insights into the nature of morphological and physiological characters used to identify species. We obtained the chloroplast genomes of I. paraguariensis and I. dumosa, and combined these with all the congeneric plastomes currently available to accomplish interspecific comparisons and multilocus analyses. We selected seven introns and nine IGSs as variable non-coding markers that were used in phylogenomic analyses. Eight extra IGSs were proposed as candidate markers. Southern South American species formed one lineage, except for I. paraguariensis, I. dumosa and I. argentina, which occupied intermediate positions among sampled taxa; Euroasiatic species formed two lineages. Some concordant relationships were retrieved from nuclear sequence data. We also conducted integral analyses, involving a supernetwork of molecular data, and a simultaneous analysis of quantitative and qualitative morphological and phytochemical characters, together with molecular data. The total evidence tree was used to study the evolution of non-molecular data, evidencing fifteen non-ambiguous synapomorphic character states and consolidating the relationships among southern South American species. More South American representatives should be incorporated to elucidate their origin. Full article
(This article belongs to the Special Issue Open Science Phyloinformatics: Resources, Methods, and Analyses)
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4 pages, 196 KB  
Case Report
Bronchioloalveolar Cell Carcinoma Presenting as a “Non-Resolving Consolidation” for Two Years
by Elias Mir, Richa Sareen, Ritu Kulshreshtha and Ashok Shah
Adv. Respir. Med. 2015, 83(3), 208-211; https://doi.org/10.5603/PiAP.2015.0033 - 30 Apr 2015
Cited by 2 | Viewed by 673
Abstract
Bronchioloalveolar carcinoma (BAC), a rare form of lung malignancy, is usually seen in non-smokers and women. Three distinct histological forms have been identified viz, mucinous, non-mucinous and mixed or indeterminate. The mucinous variety of BAC may present as a consolidation which is very [...] Read more.
Bronchioloalveolar carcinoma (BAC), a rare form of lung malignancy, is usually seen in non-smokers and women. Three distinct histological forms have been identified viz, mucinous, non-mucinous and mixed or indeterminate. The mucinous variety of BAC may present as a consolidation which is very difficult to differentiate from an infective pneumonia. We present a case of a middle aged female who was evaluated for a “non-resolving consolidation” for a period of two years. She had undergone an inconclusive bronchoscopy and had received several courses of antibiotics including anti-tuberculous therapy without relief. The size of the lesion had remained largely unchanged during this period and there was no significant clinical deterioration in the patient. Transbronchial biopsy done on presentation revealed BAC of the mucinous variety. BAC presenting as a large consolidation without significant change for a period of two years has rarely been documented in the literature. Full article
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