Search Results (644)

Stroke continues to impose an enormous morbidity and mortality burden worldwide. Stroke survivors often incur debilitating consequences that impair motor function, independence in activities of daily living and quality of life. Rehabilitation is a pivotal intervention to minimize disability and promote functional recovery following a stroke. The Internet of Medical Things, a network of connected medical devices, software and health systems that collect, store and analyze health data over the internet, is an emerging resource in neurorehabilitation for stroke survivors. Technologies such as asynchronous transmission to handle intermittent connectivity, edge computing to conserve bandwidth and lengthen device life, functional interoperability across platforms, security mechanisms scalable to resource constraints, and hybrid architectures that combine local processing with cloud synchronization help bridge the digital divide and infrastructure limitations in low-resource environments. This manuscript reviews emerging rehabilitation technologies such as robotic devices, virtual reality, brain–computer interfaces and telerehabilitation in the setting of neurorehabilitation for stroke patients. Full article

Slicing functionality makes it possible for an operator to share a 5G physical infrastructure between several virtual networks operated by different institutions. The deployed slices can support a wide range of applications with conflicting QoS targets. The coexistence of these slices on top of a common infrastructure is challenging and remains an open issue. Identifying traffic associated with a given type of slice is required to operate and control network resources in an efficient and secure way. This work proposes new algorithms operating at the physical and MAC layers. The solutions designed identify traffic generated by URLLC and eMBB slices by defining a new LightGBM framework. The algorithms can operate at the base station level in an O-RAN-type architecture. They provide a valuable input to radio resource management and traffic steering procedures. Full article

Accurate inversion of ionograms of the ionosonde is of great significance for studying ionospheric structure and radio wave propagation. Traditional inversion methods usually describe the electron density profile based on preset polynomial functions, but such functions are difficult to fully match the complex dynamic distribution characteristics of the ionosphere, especially in accurately representing special positions such as the F2 layer peak. To this end, this paper proposes an inversion model based on a Variational Autoencoder, named VSII-VAE, which realizes the mapping from ionograms to electron density profiles through an encoder–decoder structure. To enable the model to learn inversion patterns with physical significance, we introduced physical constraints into the latent variable space and the decoder, constructing a neural network inversion model that integrates data-driven approaches with physical mechanisms. Using multi-class ionograms as input and the electron density measured by Incoherent Scatter Radar as the training target, experimental results show that the electron density profiles retrieved by VSII-VAE are highly consistent with ISR observations, with errors between synthetic virtual heights and measured virtual heights generally below 5 km. On the independent test set, the model evaluation metrics reached ${\mathrm{R}}^2$ = 0.82, RMSE = 0.14 MHz, ${\mathrm{r}}_{\mathrm{p}}$ = 0.94, outperforming the ARTIST method and verifying the effectiveness and superiority of the model inversion. Full article

Accurate prognosis of the remaining useful life (RUL) for lithium-ion batteries is critical for mitigating range anxiety and ensuring the operational safety of electric vehicles. However, existing data-driven methods often struggle to maintain robustness when transferring from controlled laboratory conditions to complex, sensor-limited, real-world environments. To bridge this gap, this study presents U-H-Mamba, a novel uncertainty-aware hierarchical framework trained on a massive hybrid repository comprising over 146,000 charge–discharge cycles from both laboratory benchmarks and operational electric vehicle datasets. The proposed architecture employs a two-level design to decouple degradation dynamics, where a Multi-scale Temporal Convolutional Network functions as the base encoder to extract fine-grained electrochemical fingerprints, including derived virtual impedance proxies, from high-frequency intra-cycle measurements. Subsequently, an enhanced Pressure-Aware Multi-Head Mamba decoder models the long-range inter-cycle degradation trajectories with linear computational complexity. To guarantee reliability in safety-critical applications, a hybrid uncertainty quantification mechanism integrating Monte Carlo Dropout with Inductive Conformal Prediction is implemented to generate calibrated confidence intervals. Extensive empirical evaluations demonstrate the framework’s superior performance, achieving a RMSE of 3.2 cycles on the NASA dataset and 5.4 cycles on the highly variable NDANEV dataset, thereby outperforming state-of-the-art baselines by 20–40%. Furthermore, SHAP-based interpretability analysis confirms that the model correctly identifies physics-informed pressure dynamics as critical degradation drivers, validating its zero-shot generalization capabilities. With high accuracy and linear scalability, the U-H-Mamba model offers a viable and physically interpretable solution for cloud-based prognostics in large-scale electric vehicle fleets. Full article

Cloud computing covers a wide range of practical applications and diverse domains, yet resource scheduling and task scheduling remain significant challenges. To address this, different task scheduling algorithms are implemented across various computing systems to allocate tasks to machines, thereby enhancing performance through data mapping. To meet these challenges, a novel task scheduling model is proposed using a hybrid meta-heuristic integration with a deep learning approach. We employed this novel task scheduling model to integrate deep learning with an optimized DNN, fine-tuned using improved grey wolf–horse herd optimization, with the aim of optimizing cloud-based task allocation and overcoming makespan constraints. Initially, a user initiates a task or request within the cloud environment. Then, these tasks are assigned to Virtual Machines (VMs). Since the scheduling algorithm is constrained by the makespan objective, an optimized Deep Neural Network (DNN) model is developed to perform optimal task scheduling. Random solutions are provided to the optimized DNN, where the hidden neuron count is tuned optimally by the proposed Improved Grey Wolf–Horse Herd Optimization (IGW-HHO) algorithm. The proposed IGW-HHO algorithm is derived from both conventional Grey Wolf Optimization (GWO) and Horse Herd Optimization (HHO). The optimal solutions are acquired from the optimized DNN and processed by the proposed algorithm to efficiently allocate tasks to VMs. The experimental results are validated using various error measures and convergence analysis. The proposed DNN-IGW-HHO model achieved a lower cost function compared to other optimization methods, with a reduction of 1% compared to PSO, 3.5% compared to WOA, 2.7% compared to GWO, and 0.7% compared to HHO. The proposed task scheduling model achieved the minimal Mean Absolute Error (MAE), with performance improvements of 31% over PSO, 20.16% over WOA, 41.72% over GWO, and 9.11% over HHO. Full article

Background/Objectives: Anxiety disorders (ADs) affect up to 20% of mothers in the postpartum period, characterized by psychological symptoms (e.g., emotion dysregulation; ER) and physical symptoms (e.g., disrupted bodily awareness). Although Cognitive Behavioural Therapy effectively reduces anxiety and mood symptoms, it shows limited efficacy in addressing ER difficulties and rarely targets interoceptive dysfunction—both common in postpartum ADs. This study evaluates the effectiveness of a brief mindfulness-based intervention in improving anxiety, ER, and interoception in mothers with postpartum ADs. A secondary aim is to examine changes in brain connectivity associated with these domains. Methods: This protocol describes a proof-of-concept randomized controlled trial involving 50 postpartum mothers with ADs. Participants will be randomized to receive either a 4-week mindfulness intervention plus treatment-as-usual (TAU) or TAU alone. Participants in the mindfulness + TAU group will complete a virtual 4-week group intervention adapted from Mindfulness-Based Cognitive Therapy. The TAU group will receive usual care for 4 weeks and then be offered the mindfulness intervention. Self-report measures of anxiety, ER, and interoception will be collected at baseline, post-intervention, and at a 3-month follow-up. Resting-state functional MRI will be conducted at baseline and post-intervention to assess functional connectivity changes. This trial has been registered on ClinicalTrials.gov (NCT07262801). Results: Improvements in anxiety, ER, and interoception are anticipated, along with decreased default mode network, and increased salience network connectivity post-intervention is hypothesized. Conclusions: This study will be the first to examine the combined psychological and neural effects of mindfulness in postpartum ADs, offering a potentially scalable mind–body treatment. Full article

This paper provides a comprehensive overview of mobile network softwarization, emphasizing the technological foundations and its transformative impact on the energy efficiency of modern and future mobile networks. In the paper, a detailed analysis of communication concepts known as software-defined networking (SDN) and network function virtualization (NFV) is presented, with a description of their architectural principles, operational mechanisms, and the associated interfaces and management frameworks that enable programmability, virtualization, and centralized control in modern mobile networks. The study further explores the role of cloud computing, virtualization platforms, distributed SDN controllers, and resource orchestration systems, outlining how they collectively support mobile network scalability, automation, and service agility. To assess the maturity and evolution of mobile network softwarization, the paper reviews contemporary research directions, including SDN security, machine-learning-assisted traffic management, dynamic service function chaining, virtual network function (VNF) placement and migration, blockchain-based trust mechanisms, and artificial intelligence (AI)-enabled self-optimization. The analysis also evaluates the relationship between mobile network softwarization and energy consumption, presenting the main SDN- and NFV-based techniques that contribute to reducing mobile network power usage, such as traffic-aware control, rule placement optimization, end-host-aware strategies, VNF consolidation, and dynamic resource scaling. Findings indicate that although fifth-generation (5G) mobile network standalone deployments capable of fully exploiting softwarization remain limited, softwarized SDN/NFV-based architectures provide measurable benefits in reducing network operational costs and improving energy efficiency, especially when combined with AI-driven automation. The paper concludes that mobile network softwarization represents an essential enabler for sustainable 5G and future beyond-5G systems, while highlighting the need for continued research into scalable automation, interoperable architectures, and energy-efficient softwarized network designs. Full article

To enhance grid stability with high renewable energy penetration, this paper proposes an adaptive virtual synchronous generator (VSG) control using a backpropagation neural network (BPNN). Traditional VSG control methods exhibit limitations in handling nonlinear dynamics and suppressing power oscillations. Distinguishing from existing studies that apply BPNN solely for damping adjustment, this paper proposes a novel strategy where BPNN simultaneously regulates both VSG virtual inertia and damping coefficients by learning nonlinear relationships among inertia, angular velocity deviation, and its rate of change. A key innovation is redesigning the error function to minimize angular acceleration changes rather than frequency deviations, aligning with rotational inertia’s physical role and preventing excessive adjustments. Additionally, an adaptive damping coefficient is introduced based on optimal damping ratio principles to further suppress power oscillations. Simulation under load disturbances and grid frequency perturbations demonstrates that the proposed BPNN strategy significantly outperforms constant inertia, bang–bang, and radial basis function neural network methods. Full article

This perspective paper aims to set the stage for current development in the field of energy consumption and environmental impacts in two major digital industries: cryptocurrency mining and artificial intelligence (AI). To better understand current developments, this paper uses a comparative analytical framework of life-cycle assessment principles and high-resolution grid modeling to explore the energy impacts from academic and industry data. On the one hand, while both sectors convert energy into digital value, they operate according to completely different logics, in the sense that cryptocurrencies rely on specialized hardware (application-specific integrated circuits) and seek cheap energy, where they can function as “virtual batteries” for the network, quickly shutting down at peak times, with increasing hardware efficiency. On the other hand, AI is a much more rigid emerging energy consumer, in the sense that it needs high-quality, uninterrupted energy and advanced infrastructure for high-performance Graphics Processing Units (GPUs). The training and inference stages generate massive consumption, difficult to quantify, and AI data centers put great pressure on the electricity grid. In this sense, the transition from mining to AI is limited due to differences in infrastructure, with the only reusable advantage being access to electrical capacity. Regarding competition between the two industries, this dynamic can fragment the energy grid, as AI tends to monopolize quality energy, and how states will manage this imbalance will influence the energy and digital security of the next decade. Full article

Network function virtualization (NFV) is an emerging technology that is gaining popularity for network function migration. NFV converts a network function from a dedicated hardware device into a virtual network function (VNF), thereby improving the agility of network services and reducing management costs. A complex network service can be expressed as a service function chain (SFC) request, which consists of an ordered sequence of VNFs. Given the inherent heterogeneity and dynamic nature of network services, effective SFC deployment encounters significant unpredictable challenges. Machine learning-based methods offer the flexibility to predict and select the optimal next action based on existing data models. In this paper, we propose a deep reinforcement learning-based approach for bandwidth-aware service function chaining (DRL-BSFC). Aiming to simultaneously improve the acceptance ratio of SFC requests and maximize the total revenue for Internet service providers, DRL-BSFC integrates a graph convolutional network (GCN) for feature extraction of the underlying physical network, a sequence-to-sequence (Seq2Seq) model for capturing the order information of an SFC request, and a modified A3C (Asynchronous Advantage Actor–Critic) algorithm of deep reinforcement learning. To ensure efficient resource utilization and a higher acceptance ratio of SFC requests, the bandwidth cost for deploying an SFC is explicitly incorporated into the A3C’s reward function. The effectiveness and superiority of DRL-BSFC compared to the existing DRL-SFCP scheme are demonstrated via simulations. The performance measures include the acceptance ratio of SFC requests, the average bandwidth cost, the average remaining link bandwidth, and the average revenue-to-cost ratio under different SFC request arrival rates. Full article

Renewable energy’s growing penetration erodes traditional power systems’ inherent dynamic symmetry—balanced inertia, damping, and frequency response. This paper proposes a self-adaptive virtual synchronous generator (VSG) control strategy for a photovoltaic hybrid energy storage system (PV-HESS) based on a radial basis function (RBF) neural network. The strategy establishes a dynamic adjustment framework for inertia and damping parameters via online learning, demonstrating enhanced system stability and robustness compared to conventional VSG methods. In the structural design, the DC-side energy storage system integrates a passive filter to decouple high- and low-frequency power components, with the supercapacitor attenuating high-frequency power fluctuations and the battery stabilizing low-frequency power variations. A small-signal model of the VSG active power loop is developed, through which the parameter ranges for rotational inertia (J) and damping coefficient (D) are determined by comprehensively considering the active loop cutoff frequency, grid connection standards, stability margin, and frequency regulation time. Building on this analysis, an adaptive parameter control strategy based on an RBF neural network is proposed. Case studies show that under various conditions, the proposed RBF strategy significantly outperforms conventional methods, enhancing key performance metrics in stability and dynamic response by 16.98% to 70.37%. Full article

In edge networks, hardware failures and resource pressure may disrupt Service Function Chains (SFCs) deployed on the failed node, making it necessary to efficiently migrate multiple Virtual Network Functions (VNFs) under limited resources. To address these challenges, this paper proposes an offline reinforcement learning-based parallel migration optimization algorithm (RL-PMO) to enable parallel migration of multiple VNFs. The method follows a two-stage framework: in the first stage, improved heuristic algorithms are used to generate high-quality migration trajectories and construct a multi-scenario dataset; in the second stage, the Decision Mamba model is employed to train the policy network. With its selective modeling capability for structured sequences, Decision Mamba can capture the dependencies between VNFs and underlying resources. Combined with a twin-critic architecture and CQL regularization, the model effectively mitigates distribution shift and Q-value overestimation. The simulation results show that RL-PMO maintains approximately a 95% migration success rate across different load conditions and improves performance by about 13% under low and medium loads and up to 17% under high loads compared with typical offline RL algorithms such as IQL. Overall, RL-PMO provides an efficient, reliable, and resource-aware solution for SFC migration in node failure scenarios. Full article

The increasing threat of zoonotic malaria parasites of humans, such as Plasmodium knowlesi, make the search for improved pharmacotherapy imperative. Using protein sequence and structural analyses, phylogenetics, protein network mapping, protein–ligand interaction, and small molecule docking studies, we have identified for the first time the predicted structure, function, and druggability of the P. knowlesi heat shock protein 90s (PkHsp90s). Four isoforms were identified (in the cytosol, endoplasmic reticulum, mitochondrion, and apicoplast), and key structural differences were elucidated compared to human Hsp90s. In particular, the glycine-rich helix loop (GHL) motif of cytosolic PkHsp90 was predicted to have a straight conformation that forms a plasmodial-specific hydrophobic extension of the lid domain of the ATP-binding site, which was not observed for the cytosolic human Hsp90s, HSPC1 (Hsp90α), and HSPC3 (Hsp90β). Virtual screening identified for the first time a number of compounds from the ZINC database (ZINC22007970, ZINC724661072, and ZINC724661078) that were predicted to bind strongly to the GHL-associated pocket of PkHsp90, with weak or no binding to HSPC1. This study has provided a molecular framework in support of rational drug design, targeting PkHsp90s as a promising route for antimalarial drug development in the fight against zoonotic malaria. Full article

The development of electric quarry transport puts a significant strain on local power grids, leading to sharp peaks in consumption and degradation of power quality. Existing methods of peak smoothing, such as generation control, virtual power plants, or intelligent load management, have limited efficiency under the conditions of stochastic and high-power load profiles of industrial charging stations. A new strategy for direct charge and discharge management of a system for integrated battery energy storage (IBES) is based on dynamic iterative adjustment of load boundaries. The mathematical apparatus of the method includes the formalization of an optimization problem with constraints, which is solved using a nonlinear iterative filter with feedback. The key elements are adaptive algorithms that minimize the network power dispersion functionality (i.e., the variance of $P_{grid}\left(t\right)$ over the considered time interval) while respecting the constraints on the state of charge (SOC) and battery power. Numerical simulations and experimental studies demonstrate a 15 to 30% reduction in power dispersion compared to traditional constant power control methods. The results confirm the effectiveness of the proposed approach for optimizing energy consumption and increasing the stability of local power grids of quarry enterprises. Full article

This paper presents a portable cluster architecture based on a lightweight Kubernetes distribution designed to provide enhanced computing capabilities in isolated environments. The architecture is validated in two operational scenarios: (1) machine learning operations (MLOps) for on-site learning, fine-tuning and retraining of models and (2) web hosting for isolated or resource-constrained networks, providing resilient service delivery through failover and load balancing. The cluster leverages low-cost Raspberry Pi 4B units and virtualized nodes, integrated with Docker containerization, Kubernetes orchestration, and Kubeflow-based workflow optimization. System monitoring with Prometheus and Grafana offers continuous visibility into node health, workload distribution, and resource usage, supporting early detection of operational issues within the cluster. The results show that the proposed dual-mode cluster can function as a compact, field-deployable micro-datacenter, enabling both real-time Artificial Intelligence (AI) operations and resilient web service delivery in field environments where autonomy and reliability are critical. In addition to performance and availability measurements, power consumption, scalability bottlenecks, and basic security aspects were analyzed to assess the feasibility of such a platform under constrained conditions. Limitations are discussed, and future work includes scaling the cluster, evaluating GPU/TPU-enabled nodes, and conducting field tests in realistic tactical environments. Full article