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Search Results (568)

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Keywords = market disruptions

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22 pages, 541 KiB  
Article
Patent Licensing Strategy for Supply Chain Reshaping Under Sudden Disruptive Events
by Jianxin Zhu, Xinying Wang, Nengmin Zeng and Huijian Zhong
Systems 2025, 13(8), 672; https://doi.org/10.3390/systems13080672 (registering DOI) - 7 Aug 2025
Abstract
Supply chains are increasingly exposed to sudden disruptive events (SDEs) such as natural disasters and trade wars. We develop a multi-stage game-theoretical model to investigate a novel coping mechanism: when a firm is forced to exit the market because of SDEs, the firm [...] Read more.
Supply chains are increasingly exposed to sudden disruptive events (SDEs) such as natural disasters and trade wars. We develop a multi-stage game-theoretical model to investigate a novel coping mechanism: when a firm is forced to exit the market because of SDEs, the firm can regain profits by licensing its proprietary production tech to a competitor. We find that, compared with the scenario before SDEs, such events can even increase the profit of each manufacturer under certain conditions. Under certain conditions, the cooperative strategy (i.e., supply chain reshaping) yields a higher supply chain system profit than the non-cooperative strategy. After SDEs, the common manufacturer may either accept or reject cooperation, depending on the customer transfer rate and the cooperation cost. Notably, under the cooperation strategy, the high-tech manufacturer extracts part of the common manufacturer’s profit through patent licensing, and the existence of cooperation cost further contributes to a misalignment between the common manufacturer’s optimal decision and the supply chain system optimum. These findings contribute to the literature by identifying a novel supply chain reshaping mechanism driven by patent licensing and offer strategic guidance for firms and policymakers navigating SDE-induced market exits. Full article
(This article belongs to the Special Issue Operation and Supply Chain Risk Management)
16 pages, 1176 KiB  
Article
Evaluating the Use of Rice Husk Ash for Soil Stabilisation to Enhance Sustainable Rural Transport Systems in Low-Income Countries
by Ada Farai Shaba, Esdras Ngezahayo, Goodson Masheka and Kajila Samuel Sakuhuka
Sustainability 2025, 17(15), 7022; https://doi.org/10.3390/su17157022 - 2 Aug 2025
Viewed by 285
Abstract
Rural roads are critical for connecting isolated communities to essential services such as education and health and administrative services, as well as production and market opportunities in low-income countries. More than 70% of movements of people and goods in Sub-Saharan Africa are heavily [...] Read more.
Rural roads are critical for connecting isolated communities to essential services such as education and health and administrative services, as well as production and market opportunities in low-income countries. More than 70% of movements of people and goods in Sub-Saharan Africa are heavily reliant on rural transport systems, using both motorised but mainly alternative means of transport. However, rural roads often suffer from poor construction due to the use of low-strength, in situ soils and limited financial resources, leading to premature failures and subsequent traffic disruptions with significant economic losses. This study investigates the use of rice husk ash (RHA), a waste byproduct from rice production, as a sustainable supplement to Ordinary Portland Cement (OPC) for soil stabilisation in order to increase durability and sustainability of rural roads, hence limit recurrent maintenance needs and associated transport costs and challenges. To conduct this study, soil samples collected from Mulungushi, Zambia, were treated with combinations of 6–10% OPC and 10–15% RHA by weight. Laboratory tests measured maximum dry density (MDD), optimum moisture content (OMC), and California Bearing Ratio (CBR) values; the main parameters assessed to ensure the quality of road construction soils. Results showed that while the MDD did not change significantly and varied between 1505 kg/m3 and 1519 kg/m3, the OMC increased hugely from 19.6% to as high as 26.2% after treatment with RHA. The CBR value improved significantly, with the 8% OPC + 10% RHA mixture achieving the highest resistance to deformation. These results suggest that RHA can enhance the durability and sustainability of rural roads and hence improve transport systems and subsequently improve socioeconomic factors in rural areas. Full article
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30 pages, 1293 KiB  
Article
Obstacles and Drivers of Sustainable Horizontal Logistics Collaboration: Analysis of Logistics Providers’ Behaviour in Slovenia
by Ines Pentek and Tomislav Letnik
Sustainability 2025, 17(15), 7001; https://doi.org/10.3390/su17157001 - 1 Aug 2025
Viewed by 228
Abstract
The logistics industry faces challenges from evolving consumer expectations, technological advances, sustainability demands, and market disruptions. Logistics collaboration is in theory perceived as one of the most promising solutions to solve these issues, but here are still a lot of challenges that needs [...] Read more.
The logistics industry faces challenges from evolving consumer expectations, technological advances, sustainability demands, and market disruptions. Logistics collaboration is in theory perceived as one of the most promising solutions to solve these issues, but here are still a lot of challenges that needs to be better understood and addressed. While vertical collaboration among supply chain actors is well advanced, horizontal collaboration among competing service providers remains under-explored. This study developed a novel methodology based on the COM-B behaviour-change framework to better understand the main challenges, opportunities, capabilities and drivers that would motivate competing companies to exploit the potential of horizontal logistics collaboration. A survey was designed and conducted among 71 logistics service providers in Slovenia, chosen for its fragmented market and low willingness to collaborate. Statistical analysis reveals cost reduction (M = 4.21/5) and improved vehicle utilization (M = 4.29/5) as the primary motivators. On the other hand, maintaining company reputation (M = 4.64/5), fair resource sharing (M = 4.20/5), and transparency of logistics processes (M = 4.17/5) all persist as key enabling conditions. These findings underscore the pivotal role of behavioural drivers and suggest strategies that combine economic incentives with targeted trust-building measures. Future research should employ experimental designs in diverse national contexts and integrate vertical–horizontal approaches to validate causal pathways and advance theory. Full article
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33 pages, 1497 KiB  
Article
Beyond Compliance: How Disruptive Innovation Unleashes ESG Value Under Digital Institutional Pressure
by Fang Zhang and Jianhua Zhu
Systems 2025, 13(8), 644; https://doi.org/10.3390/systems13080644 - 1 Aug 2025
Viewed by 431
Abstract
Amid intensifying global ESG regulations and the expanding influence of green finance, China’s digital economy policies have emerged as key institutional instruments for promoting corporate sustainability. Leveraging the implementation of the National Big Data Comprehensive Pilot Zone as a quasi-natural experiment, this study [...] Read more.
Amid intensifying global ESG regulations and the expanding influence of green finance, China’s digital economy policies have emerged as key institutional instruments for promoting corporate sustainability. Leveraging the implementation of the National Big Data Comprehensive Pilot Zone as a quasi-natural experiment, this study utilizes panel data of Chinese listed firms from 2009 to 2023 and applies multi-period Difference-in-Differences (DID) and Spatial DID models to rigorously identify the policy’s effects on corporate ESG performance. Empirical results indicate that the impact of digital economy policy is not exerted through a direct linear pathway but operates via three institutional mechanisms, enhanced information transparency, eased financing constraints, and expanded fiscal support, collectively constructing a logic of “institutional embedding–governance restructuring.” Moreover, disruptive technological innovation significantly amplifies the effects of the transparency and fiscal mechanisms, but exhibits no statistically significant moderating effect on the financing constraint pathway, suggesting a misalignment between innovation heterogeneity and financial responsiveness. Further heterogeneity analysis confirms that the policy effect is concentrated among firms characterized by robust governance structures, high levels of property rights marketization, and greater digital maturity. This study contributes to the literature by developing an integrated moderated mediation framework rooted in institutional theory, agency theory, and dynamic capabilities theory. The findings advance the theoretical understanding of ESG policy transmission by unpacking the micro-foundations of institutional response under digital policy regimes, while offering actionable insights into the strategic alignment of digital transformation and sustainability-oriented governance. Full article
(This article belongs to the Section Systems Practice in Social Science)
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18 pages, 475 KiB  
Article
How Environmental Turbulence Shapes the Path from Resilience to Sustainability: Useful Insights Gathered from Small and Medium Enterprises (SMEs)
by Ahmet Serdar İbrahimcioğlu and Hakan Kitapçı
Sustainability 2025, 17(15), 6938; https://doi.org/10.3390/su17156938 - 30 Jul 2025
Viewed by 207
Abstract
In the context of small and medium-sized enterprises (SMEs), organizational resilience has emerged as a critical capability for navigating dynamic and turbulent environments. The ability of firms to sustain their performance despite external disruptions, particularly those arising from market and technological change, is [...] Read more.
In the context of small and medium-sized enterprises (SMEs), organizational resilience has emerged as a critical capability for navigating dynamic and turbulent environments. The ability of firms to sustain their performance despite external disruptions, particularly those arising from market and technological change, is paramount for achieving long-term sustainability. This study offers a novel contribution by examining how two key dimensions of environmental turbulence—market turbulence and technological turbulence—moderate the relationship between organizational resilience capacity and sustainability performance. Our empirical findings, based on data from 423 SMEs, demonstrate that while organizational resilience positively correlates with sustainability performance, this relationship is significantly weakened under high levels of market and technological turbulence, indicating a negative moderating effect. These results advance resource-based and dynamic capabilities theory by highlighting the contingent nature of resilience in unstable contexts. Furthermore, this study provides practical guidance. SMEs should strategically invest in resilience-building efforts and continuously adapt their strategies in response to environmental fluctuations. Targeted approaches to managing different forms of turbulence and forming resilience-oriented collaborations can enhance sustainability outcomes. This research makes significant contributions to theory and practice; however, there are limitations that future research should take into account in order to appropriately utilize this study’s findings. Full article
(This article belongs to the Section Economic and Business Aspects of Sustainability)
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18 pages, 376 KiB  
Article
Resilience or Retreat? The Impact of COVID-19 on Entrepreneurial Intentions of Undergraduate Business Students
by Anas Al-Fattal and Michael Martin
COVID 2025, 5(8), 117; https://doi.org/10.3390/covid5080117 - 26 Jul 2025
Viewed by 225
Abstract
The COVID-19 pandemic fundamentally disrupted assumptions about entrepreneurship, career planning, and professional development. This study explored how the pandemic influenced the entrepreneurial intentions of undergraduate business students in the United States. Using a qualitative methodology based on in-depth interviews with 31 students at [...] Read more.
The COVID-19 pandemic fundamentally disrupted assumptions about entrepreneurship, career planning, and professional development. This study explored how the pandemic influenced the entrepreneurial intentions of undergraduate business students in the United States. Using a qualitative methodology based on in-depth interviews with 31 students at a public Midwestern university, the research interpreted student narratives through the lenses of effectuation theory, resilience theory, and the theory of planned behavior. Findings revealed that many participants reframed entrepreneurship as a strategy for navigating economic uncertainty and enhancing personal agency. Students reported valuing adaptability, resourcefulness, and opportunity recognition, often experimenting with side hustles during the pandemic as a means of resilience. Their entrepreneurial thinking shifted from purely economic motivations toward aspirations for flexibility, self-fulfillment, and purposeful work. The study highlights the formative role of crisis contexts in shaping entrepreneurial identity among emerging professionals. It suggests that entrepreneurship education should move beyond traditional models, fostering skills for navigating complexity and building resilience. In doing so, the findings contribute to broader conversations about youth entrepreneurship, post-pandemic career development, and the evolving demands of the labor market in times of disruption. Full article
(This article belongs to the Section COVID Public Health and Epidemiology)
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17 pages, 1359 KiB  
Article
More Care, More Workers? Gauging the Impact of Child Care Access on Labor Force Participation
by John Reaves, Hope O. Akaeze, Holli A. Schlukebir, Steven R. Miller, Henry O. Akaeze and Jamie Heng-Chieh Wu
Soc. Sci. 2025, 14(8), 458; https://doi.org/10.3390/socsci14080458 - 24 Jul 2025
Viewed by 346
Abstract
This study investigates the critical link between child care accessibility and local labor force participation, addressing a gap in current research that often lacks local spatial granularity. While over half of the U.S. population resides in child care deserts, disproportionately affecting rural, low-income, [...] Read more.
This study investigates the critical link between child care accessibility and local labor force participation, addressing a gap in current research that often lacks local spatial granularity. While over half of the U.S. population resides in child care deserts, disproportionately affecting rural, low-income, and minority communities, the economic implications for local labor markets remain underexplored. Leveraging Michigan child care license data and Census tract-level demographic and employment characteristics, this research employs a spatial econometric approach to estimate the impact of geographic distance to child care facilities on labor supply using descriptive data. Our findings consistently demonstrate that increased distance to child care is significantly associated with reduced labor force participation. While female labor force participation is lower in areas with constrained access to child care, we also found that households with two parents are also less likely to have full labor force participation when access to child care is constrained. The cost-effective framework used here can be replicated to identify specific communities most impacted by child care-related employment disruptions. The analytical findings can be instrumental in targeting and prioritizing child care policy interventions. Full article
(This article belongs to the Section Childhood and Youth Studies)
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26 pages, 1378 KiB  
Article
Effects of Electricity Price Volatility, Energy Mix and Training Interval on Prediction Accuracy: An Investigation of Adaptive and Static Regression Models for Germany, France and the Czech Republic
by Marek Pavlík and Matej Bereš
Energies 2025, 18(15), 3893; https://doi.org/10.3390/en18153893 - 22 Jul 2025
Viewed by 308
Abstract
Electricity markets in Europe have undergone major changes in the last decade, mainly due to the increasing share of variable renewable energy sources (RES), changing demand patterns, and geopolitical factors—particularly the war in Ukraine, tensions over energy imports, and disruptions in natural gas [...] Read more.
Electricity markets in Europe have undergone major changes in the last decade, mainly due to the increasing share of variable renewable energy sources (RES), changing demand patterns, and geopolitical factors—particularly the war in Ukraine, tensions over energy imports, and disruptions in natural gas supplies. These changes have led to increased electricity price volatility, reducing the reliability of traditional forecasting tools. This research analyses the potential of static and adaptive linear regression as electricity price forecasting tools in the context of three countries with different energy mixes: Germany, France and the Czech Republic. The static regression approach was compared with an adaptive approach based on incremental model updates at monthly intervals. Testing was carried out in three different scenarios combining stable and turbulent market periods. The quantitative results showed that the adaptive model achieved a lower MAE and RMSE, especially when trained on data from high-volatility periods. However, models trained under turbulent conditions performed poorly in stable environments due to a shift in market dynamics. The results supported several of the hypotheses formulated and demonstrated the need for localised, flexible and continuously updated forecasting. Limitations of the adaptive approach and suggestions for future research, including changing the length of training windows and the use of seasonal models, are also discussed. The research confirms that modern markets require adaptive analytical approaches that account for changing RES dynamics and country specificities. Full article
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22 pages, 430 KiB  
Article
Corporate Social Responsibility as a Buffer in Times of Crisis: Evidence from China’s Stock Market During COVID-19
by Dongdong Huang, Shuyu Hu and Haoxu Wang
Sustainability 2025, 17(14), 6636; https://doi.org/10.3390/su17146636 - 21 Jul 2025
Viewed by 475
Abstract
Prior research often portrays Corporate Social Responsibility (CSR) as a coercive institutional force compelling firms to passively conform for legitimacy. More recent studies, however, suggest firms actively pursue CSR to gain sustainable competitive advantages. Yet, how and when CSR buffers firms against adverse [...] Read more.
Prior research often portrays Corporate Social Responsibility (CSR) as a coercive institutional force compelling firms to passively conform for legitimacy. More recent studies, however, suggest firms actively pursue CSR to gain sustainable competitive advantages. Yet, how and when CSR buffers firms against adverse shocks of crises remains insufficiently understood. This study addresses this gap by using multiple regression analysis to examine the buffering effects of CSR investments during the COVID-19 crisis, which severely disrupted capital markets and firm valuation. Drawing on signaling theory and CSR literature, we analyze the stock market performance of China’s A-share listed firms using a sample of 2577 observations as of the end of 2019. Results indicate that firms with higher CSR investments experienced significantly greater cumulative abnormal returns during the pandemic. Moreover, the buffering effect is amplified among firms with higher debt burdens, greater financing constraints, and those operating in regions with stronger social trust and more severe COVID-19 impact. These findings are robust across multiple robustness checks. This study highlights the strategic value of CSR as a resilience mechanism during crises and supports a more proactive view of CSR engagement for sustainable development, complementing the traditional legitimacy-focused perspective in existing literature. Full article
(This article belongs to the Section Economic and Business Aspects of Sustainability)
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18 pages, 1349 KiB  
Article
Analysing Market Volatility and Economic Policy Uncertainty of South Africa with BRIC and the USA During COVID-19
by Thokozane Ramakau, Daniel Mokatsanyane, Sune Ferreira-Schenk and Kago Matlhaku
J. Risk Financial Manag. 2025, 18(7), 400; https://doi.org/10.3390/jrfm18070400 - 19 Jul 2025
Viewed by 456
Abstract
The contagious COVID-19 disease not only brought about a global health crisis but also a disruption in the global economy. The uncertainty levels regarding the impact of the disease increased volatility. This study analyses stock market volatility and Economic Policy Uncertainty (EPU) of [...] Read more.
The contagious COVID-19 disease not only brought about a global health crisis but also a disruption in the global economy. The uncertainty levels regarding the impact of the disease increased volatility. This study analyses stock market volatility and Economic Policy Uncertainty (EPU) of South Africa (SA) with that of the United States of America (USA) and Brazil, Russia, India, and China (BRIC) during the COVID-19 pandemic. The study aims to analyse volatility spillovers from a developed market (USA) to emerging markets (BRIC countries) and also to examine the causality between EPU and stock returns during the COVID-19 pandemic. By employing the GARCH-in-Mean model from a sample of daily returns of national equity market indices from 1 January 2020 to 31 March 2022, SA and China are shown to be the most volatile during the pandemic. By using the diagonal Baba, Engle, Kraft, and Kroner (BEKK) model to analyse spillover effects, evidence of spillover effects from the US to the emerging countries is small but statistically significant, with SA showing the strongest impact from US market shocks. From the Granger causality test, Brazil’s and India’s equity markets are shown to be highly sensitive to changes in EPU relative to the other countries. Full article
(This article belongs to the Section Economics and Finance)
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18 pages, 3989 KiB  
Article
Morphological Analysis, Bud Differentiation, and Regulation of “Bud Jumping” Phenomenon in Oncidium Using Plant Growth Regulators
by Hanqiao Lan, Le Liu, Weishi Li, Daicheng Hao, Shanzhi Lin, Beilei Ye, Minqiang Tang and Peng Ling
Horticulturae 2025, 11(7), 852; https://doi.org/10.3390/horticulturae11070852 - 18 Jul 2025
Viewed by 410
Abstract
Oncidium has an important market value, with important high-grade cut orchids and potted flowers on the flower market. In the Oncidium cut flowers production industry, there is a common phenomenon that the development of vegetative buds disrupts the normal generation cycle of the [...] Read more.
Oncidium has an important market value, with important high-grade cut orchids and potted flowers on the flower market. In the Oncidium cut flowers production industry, there is a common phenomenon that the development of vegetative buds disrupts the normal generation cycle of the inflorescence induction, so-called “bud jumping”. In this study, vegetative bud differentiation and flower bud differentiation were divided into three stages, namely, the initial stage of differentiation, the leaf primordial/flower primordial differentiation stage, and the late stage of leaf bud/flower bud differentiation, as observed by paraffin sectioning. Secondly, we analyzed the differences between the vegetative buds of “bud jumping” plants and the flower buds of normal flowering plants by transcriptome sequencing. The transcriptome analysis results revealed significant differences among plant signaling pathways, particularly in gibberellins, auxins, and cytokinins, which play important roles in this phenomenon’s formation. In conjunction with the transcriptome analysis, the researchers conducted field experiments by applying plant growth regulators on the newborn pseudobulb of young Oncidium plants measuring approximately 49 mm in length. The results showed that the treatment groups of 100 mg/L of gibberellic acid (GA3) and 100 mg/L GA3 + 10 mg/L 6-Benziladenine (6-BA) exhibited the highest rate of flower bud differentiation instead of the least “bud jumping” phenomenon, and the “bud jumping” phenomenon was significantly reduced under 25 mg/L, 50 mg/L, and 75 mg/L 3-indoleacetic acid (IAA) treatments. The application of exogenous gibberellins, cytokinins, and auxins can effectively reduce the occurrence of “bud jumping”. Full article
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18 pages, 849 KiB  
Article
Decision Optimization of Manufacturing Supply Chain Based on Resilience
by Feng Lyu, Jiajie Zhang, Fen Liu and Huili Chu
Sustainability 2025, 17(14), 6519; https://doi.org/10.3390/su17146519 - 16 Jul 2025
Viewed by 344
Abstract
Manufacturing serves as a vital indicator of a nation’s economic strength, technological advancement, and comprehensive competitiveness. In the context of the VUCA (Volatility, Uncertainty, Complexity, Ambiguity) business environment and globalization, uncertain market demand has intensified supply chain disruption risks, necessitating resilience strategies to [...] Read more.
Manufacturing serves as a vital indicator of a nation’s economic strength, technological advancement, and comprehensive competitiveness. In the context of the VUCA (Volatility, Uncertainty, Complexity, Ambiguity) business environment and globalization, uncertain market demand has intensified supply chain disruption risks, necessitating resilience strategies to enhance supply chain stability. This study proposes five resilience strategies—establishing an information sharing system, multi-sourcing, alternative suppliers, safety stock, and alternative transportation plans—while integrating sustainability requirements. A multi-objective mixed-integer optimization model was developed to balance cost efficiency, resilience, and environmental sustainability. Comparative analysis reveals that the resilience-embedded model outperforms traditional approaches in both cost control and risk mitigation capabilities. The impact of parameter variations on the model results was examined through sensitivity analysis. The findings demonstrate that the proposed optimization model effectively enhances supply chain resilience—mitigating cost fluctuations while maintaining robust demand fulfillment under uncertainties. Full article
(This article belongs to the Special Issue Decision-Making in Sustainable Management)
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26 pages, 1389 KiB  
Article
Forest Biomass Fuels and Energy Price Stability: Policy Implications for U.S. Gasoline and Diesel Markets
by Chukwuemeka Valentine Okolo and Andres Susaeta
Energies 2025, 18(14), 3732; https://doi.org/10.3390/en18143732 - 15 Jul 2025
Viewed by 242
Abstract
U.S. gasoline and diesel prices are often volatile, driven by geopolitical risks and disruptions in the fossil fuel market. Forest biomass fuels, particularly renewable diesel derived from logging residues, offer a low-carbon alternative with the potential to stabilize fuel prices. This study evaluates [...] Read more.
U.S. gasoline and diesel prices are often volatile, driven by geopolitical risks and disruptions in the fossil fuel market. Forest biomass fuels, particularly renewable diesel derived from logging residues, offer a low-carbon alternative with the potential to stabilize fuel prices. This study evaluates whether biomass can moderate fuel price volatility using ANOVA, Tukey post hoc tests, and quadratic regression based on monthly data for biomass production, inventories, and retail fuel prices. Findings reveal the existence of a significant nonlinear relationship between forest biomass inventory levels and fossil fuel prices. Average gasoline prices peaked in the medium-inventory group (M = 0.837) and dropped in the high-inventory group (M = 0.684). Diesel prices followed a similar pattern, with the highest values in the medium-inventory group (M = 0.963) and the lowest in the high-inventory group (M = 0.759). One-way ANOVA results were statistically significant for both gasoline (F(2, 99) = 7.39, p = 0.001) and diesel (F(2, 99) = 7.22, p = 0.0012). Tukey tests confirmed that diesel prices fell significantly from both medium to high and low to high-inventory levels. This result remains robust when using the biomass index level and the biomass production level. These results indicate a threshold effect: only at higher biomass inventories do fossil fuel prices decline, suggesting a potential for substitution. However, current policies inadequately support biomass integration, highlighting the need for targeted reforms. Full article
(This article belongs to the Special Issue Emerging Trends in Energy Economics: 3rd Edition)
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17 pages, 3867 KiB  
Article
A Case-Study-Based Comparative Analysis of Using Prefabricated Structures in Industrial Buildings
by Abdelhadi Salih, Cynthia Changxin Wang, Rui Tian and Mohammad Mojtahedi
Buildings 2025, 15(14), 2416; https://doi.org/10.3390/buildings15142416 - 10 Jul 2025
Viewed by 398
Abstract
Construction costs have increased significantly since the COVID-19 pandemic due to supply chain disruption, labour shortages, and construction material price hikes. The market is increasingly demanding innovative construction methods that can save construction costs, reduce construction time, and minimise waste and carbon emission. [...] Read more.
Construction costs have increased significantly since the COVID-19 pandemic due to supply chain disruption, labour shortages, and construction material price hikes. The market is increasingly demanding innovative construction methods that can save construction costs, reduce construction time, and minimise waste and carbon emission. The prefabrication system has been used for years in industrial construction, resulting in better performance in regard to structure stability, the control of wastage, and the optimisation of construction time and cost. In addition, prefabrication has had a positive contribution on resource utilisation in the construction industry. There are various types of prefabricated wall systems. However, the majority of comparative studies have focused on comparing each prefabrication wall system against the conventional construction system, while limited research has been conducted to compare different prefabrication structures. This study examined four prominent prefabricated wall systems, i.e., precast walls, tilt-up walls, prefabricated steel-frame walls, and on-site-cut steel-frame walls, to determine which one is more suitable for the construction of industrial buildings to minimise cost, time delay, and labourer utilisation on construction sites, as well as to enhance structure durability, construction efficiency, and sustainability. One primary case project and five additional projects were included in this study. For the primary case project, data were collected and analysed; for example, a subcontractor cost comparison for supply and installation was conducted, and shop drawings, construction procedures, timelines, and site photos were collected. For the additional five projects, the overall cost data were compared. The main research finding of this study is that factory-made precast walls and tilt-up wall panels require similar construction time. However, on average, tilt-up prefabrication construction can reduce the cost by around 23.55%. It was also found that prefabricated frame walls provide cost and time savings of around 39% and 10.5%, respectively. These findings can provide architects, developers, builders, suppliers, regulators, and other stakeholders with a comprehensive insight into selecting a method of wall construction that can achieve greater efficiency, cost savings, and environmental sustainability in the construction of industrial and commercial buildings. Full article
(This article belongs to the Collection Buildings for the 21st Century)
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25 pages, 1759 KiB  
Review
Harnessing the Potential of Antibacterial and Antibiofilm Phytochemicals in the Combat Against Superbugs: A One Health Perspective
by Suma Sarojini, Saranya Jayaram, Sandhya Kalathilparambil Santhosh, Pragyan Priyadarshini, Manikantan Pappuswamy and Balamuralikrishnan Balasubramanian
Antibiotics 2025, 14(7), 692; https://doi.org/10.3390/antibiotics14070692 - 9 Jul 2025
Viewed by 660
Abstract
The war between humans and bacteria started centuries ago. With the advent of antibiotics, there was a temporary ceasefire in this war, but the scenario soon started becoming worse with the emergence of drug-resistant strains within years of the deployment of antibiotics in [...] Read more.
The war between humans and bacteria started centuries ago. With the advent of antibiotics, there was a temporary ceasefire in this war, but the scenario soon started becoming worse with the emergence of drug-resistant strains within years of the deployment of antibiotics in the market. With the surge in the misuse of antibiotics, there was a drastic increase in the number of multidrug-resistant (MDR) and extensively drug-resistant bacterial strains, even to antibiotics like Methicillin and vancomycin, aggravating the healthcare scenario. The threat of MDR ESKAPE pathogens is particularly high in nosocomial infections, where biofilms formed by bacteria create a protective barrier that makes them highly resistant to antibiotics, complicating the treatment efforts. Scientists are looking at natural and sustainable solutions, as several studies have projected deaths contributed by drug-resistant bacteria to go beyond 50 million by 2050. Many plant-derived metabolites have shown excellent antibacterial and antibiofilm properties that can be tapped for combating superbugs. The present review explores the current status of various studies on antibacterial plant metabolites like alkaloids and flavonoids and their mechanisms in disrupting biofilms and killing bacteria by way of inhibiting key survival strategies of bacteria like motility, quorum-sensing, reactive oxygen species production, and adhesion. These mechanisms were found to be varied in Gram-positive, Gram-negative, and acid-fast bacteria like Mycobacterium tuberculosis, which will be discussed in detail. The successful tapping of the benefits of such plant-derived chemicals in combination with evolving techniques of nanotechnology and targeted drug delivery can go a long way in achieving the goal of One Health, which advocates the unity of multiple practices for the optimal health of people, animals, and the environment. Full article
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