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51 pages, 4233 KiB  
Article
Tackling Blind Spot Challenges in Metaheuristics Algorithms Through Exploration and Exploitation
by Matej Črepinšek, Miha Ravber, Luka Mernik and Marjan Mernik
Mathematics 2025, 13(10), 1580; https://doi.org/10.3390/math13101580 - 11 May 2025
Cited by 1 | Viewed by 385
Abstract
This paper defines blind spots in continuous optimization problems as global optima that are inherently difficult to locate due to deceptive, misleading, or barren regions in the fitness landscape. Such regions can mislead the search process, trap metaheuristic algorithms (MAs) in local optima, [...] Read more.
This paper defines blind spots in continuous optimization problems as global optima that are inherently difficult to locate due to deceptive, misleading, or barren regions in the fitness landscape. Such regions can mislead the search process, trap metaheuristic algorithms (MAs) in local optima, or hide global optima in isolated regions, making effective exploration particularly challenging. To address the issue of premature convergence caused by blind spots, we propose LTMA+ (Long-Term Memory Assistance Plus), a novel meta-approach that enhances the search capabilities of MAs. LTMA+ extends the original Long-Term Memory Assistance (LTMA) by introducing strategies for handling duplicate evaluations, shifting the search away from over-exploited regions and dynamically toward unexplored areas and thereby improving global search efficiency and robustness. We introduce the Blind Spot benchmark, a specialized test suite designed to expose weaknesses in exploration by embedding global optima within deceptive fitness landscapes. To validate LTMA+, we benchmark it against a diverse set of MAs selected from the EARS framework, chosen for their different exploration mechanisms and relevance to continuous optimization problems. The tested MAs include ABC, LSHADE, jDElscop, and the more recent GAOA and MRFO. The experimental results show that LTMA+ improves the success rates for all the tested MAs on the Blind Spot benchmark statistically significantly, enhances solution accuracy, and accelerates convergence to the global optima compared to standard MAs with and without LTMA. Furthermore, evaluations on standard benchmarks without blind spots, such as CEC’15 and the soil model problem, confirm that LTMA+ maintains strong optimization performance without introducing significant computational overhead. Full article
(This article belongs to the Section E1: Mathematics and Computer Science)
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18 pages, 6665 KiB  
Article
Multiple LPA3 Receptor Agonist Binding Sites Evidenced Under Docking and Functional Studies
by K. Helivier Solís, M. Teresa Romero-Ávila, Ruth Rincón-Heredia, Sergio Romero-Romero, José Correa-Basurto and J. Adolfo García-Sáinz
Int. J. Mol. Sci. 2025, 26(9), 4123; https://doi.org/10.3390/ijms26094123 - 26 Apr 2025
Viewed by 653
Abstract
Comparative studies using lysophosphatidic acid (LPA) and the synthetic agonist, oleoyl-methoxy glycerophosphothionate (OMPT), in cells expressing the LPA3 receptor revealed differences in the action of these agents. The possibility that more than one recognition cavity might exist for these ligands in the [...] Read more.
Comparative studies using lysophosphatidic acid (LPA) and the synthetic agonist, oleoyl-methoxy glycerophosphothionate (OMPT), in cells expressing the LPA3 receptor revealed differences in the action of these agents. The possibility that more than one recognition cavity might exist for these ligands in the LPA3 receptor was considered. We performed agonist docking studies exploring the whole protein to obtain tridimensional details of the ligand–receptor interaction. Functional in cellulo experiments using mutants were also executed. Our work includes blind docking using the unrefined and refined proteins subjected to hot spot predictions. Distinct ligand protonation (charge −1 and −2) states were evaluated. One LPA recognition cavity is located near the lower surface of the receptor close to the cytoplasm (Lower Cavity). OMPT displayed an affinity for an additional identification cavity detected in the transmembrane and extracellular regions (Upper Cavity). Docking targeted to Trp102 favored binding of both ligands in the transmembrane domain near the extracellular areas (Upper Cavity), but the associating amino acids were not identical due to close sub-cavities. A receptor model was generated using AlphaFold3, which properly identified the transmembrane regions of the sequence and co-modeled the lipid environment accordingly. These two models independently generated (with and without the membrane) and adopted essentially the same conformation, validating the data obtained. A DeepSite analysis of the model predicted two main binding pockets, providing additional confidence in the predicted ligand-binding regions and support for the relevance of the docking-based interaction models. In addition, mutagenesis was performed of the amino acids of the two detected cavities. In the in cellulo studies, LPA action was much less affected by the distinct mutations than that of OMPT (which was almost abolished). Therefore, docking and functional data indicate the presence of distinct agonist binding cavities in the LPA3 receptor. Full article
(This article belongs to the Section Molecular Biophysics)
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17 pages, 5419 KiB  
Article
Fiber/Free-Space Optics with Open Radio Access Networks Supplements the Coverage of Millimeter-Wave Beamforming for Future 5G and 6G Communication
by Cheng-Kai Yao, Hsin-Piao Lin, Chiun-Lang Cheng, Ming-An Chung, Yu-Shian Lin, Wen-Bo Wu, Chun-Wei Chiang and Peng-Chun Peng
Fibers 2025, 13(4), 39; https://doi.org/10.3390/fib13040039 - 2 Apr 2025
Cited by 2 | Viewed by 913
Abstract
Conceptually, this paper aims to help reduce the communication blind spots originating from the design of millimeter-wave (mmW) beamforming by deploying radio units of an open radio access network (O-RAN) with free-space optics (FSOs) as the backhaul and the fiber-optic link as the [...] Read more.
Conceptually, this paper aims to help reduce the communication blind spots originating from the design of millimeter-wave (mmW) beamforming by deploying radio units of an open radio access network (O-RAN) with free-space optics (FSOs) as the backhaul and the fiber-optic link as the fronthaul. At frequencies exceeding 24 GHz, the transmission reach of 5G/6G beamforming is limited to a few hundred meters, and the periphery area of the sector operational range of beamforming introduces a communication blind spot. Using FSOs as the backhaul and a fiber-optic link as the fronthaul, O-RAN empowers the radio unit to extend over greater distances to supplement the communication range that mmW beamforming cannot adequately cover. Notably, O-RAN is a prime example of next-generation wireless networks renowned for their adaptability and open architecture to enhance the cost-effectiveness of this integration. A 200 meter-long FSO link for backhaul and a fiber-optic link of up to 10 km for fronthaul were erected, thereby enabling the reach of communication services from urban centers to suburban and remote rural areas. Furthermore, in the context of beamforming, reinforcement learning (RL) was employed to optimize the error vector magnitude (EVM) by dynamically adjusting the beamforming phase based on the communication user’s location. In summary, the integration of RL-based mmW beamforming with the proposed O-RAN communication setup is operational. It lends scalability and cost-effectiveness to current and future communication infrastructures in urban, peri-urban, and rural areas. Full article
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20 pages, 18281 KiB  
Article
IMU Sensor-Based Worker Behavior Recognition and Construction of a Cyber–Physical System Environment
by Sehwan Park, Minkyo Youm and Junkyeong Kim
Sensors 2025, 25(2), 442; https://doi.org/10.3390/s25020442 - 13 Jan 2025
Cited by 3 | Viewed by 1698
Abstract
According to South Korea’s Ministry of Employment and Labor, approximately 25,000 construction workers suffered from various injuries between 2015 and 2019. Additionally, about 500 fatalities occur annually, and multiple studies are being conducted to prevent these accidents and quickly identify their occurrence to [...] Read more.
According to South Korea’s Ministry of Employment and Labor, approximately 25,000 construction workers suffered from various injuries between 2015 and 2019. Additionally, about 500 fatalities occur annually, and multiple studies are being conducted to prevent these accidents and quickly identify their occurrence to secure the golden time for the injured. Recently, AI-based video analysis systems for detecting safety accidents have been introduced. However, these systems are limited to areas where CCTV is installed, and in locations like construction sites, numerous blind spots exist due to the limitations of CCTV coverage. To address this issue, there is active research on the use of MEMS (micro-electromechanical systems) sensors to detect abnormal conditions in workers. In particular, methods such as using accelerometers and gyroscopes within MEMS sensors to acquire data based on workers’ angles, utilizing three-axis accelerometers and barometric pressure sensors to improve the accuracy of fall detection systems, and measuring the wearer’s gait using the x-, y-, and z-axis data from accelerometers and gyroscopes are being studied. However, most methods involve use of MEMS sensors embedded in smartphones, typically attaching the sensors to one or two specific body parts. Therefore, in this study, we developed a novel miniaturized IMU (inertial measurement unit) sensor that can be simultaneously attached to multiple body parts of construction workers (head, body, hands, and legs). The sensor integrates accelerometers, gyroscopes, and barometric pressure sensors to measure various worker movements in real time (e.g., walking, jumping, standing, and working at heights). Additionally, incorporating PPG (photoplethysmography), body temperature, and acoustic sensors, enables the comprehensive observation of both physiological signals and environmental changes. The collected sensor data are preprocessed using Kalman and extended Kalman filters, among others, and an algorithm was proposed to evaluate workers’ safety status and update health-related data in real time. Experimental results demonstrated that the proposed IMU sensor can classify work activities with over 90% accuracy even at a low sampling rate of 15 Hz. Furthermore, by integrating internal filtering, communication modules, and server connectivity within an application, we established a cyber–physical system (CPS), enabling real-time monitoring and immediate alert transmission to safety managers. Through this approach, we verified improved performance in terms of miniaturization, measurement accuracy, and server integration compared to existing commercial sensors. Full article
(This article belongs to the Special Issue Sensor-Based Human Activity Recognition)
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14 pages, 9538 KiB  
Technical Note
Eliminating Inductive Coupling in Small-Loop TEM Through Differential Measurement with Opposing Coils
by Xinghai Chen, Haiyan Yang, Tong Xia, Xiaoping Wu and Shengdong Liu
Remote Sens. 2025, 17(2), 254; https://doi.org/10.3390/rs17020254 - 13 Jan 2025
Viewed by 872
Abstract
The small-loop transient electromagnetic method (TEM) refers to a system in which the coil frame length or diameter is less than 2 m. Due to the inductive effects of the multi-turn coils used for both transmission and reception, the induced electromotive force in [...] Read more.
The small-loop transient electromagnetic method (TEM) refers to a system in which the coil frame length or diameter is less than 2 m. Due to the inductive effects of the multi-turn coils used for both transmission and reception, the induced electromotive force in the measuring coil increases, causing a reduction in the decay rate and an extension of the shutoff time. This results in coupling between the primary and secondary fields in early-time signals, making them difficult to separate and creating a detection blind spot in the shallow subsurface. The opposing coil TEM transmission and reception method can significantly reduce early-time signal distortion caused by coil inductance. However, this approach is constrained by the physical symmetry of the coil dimensions, which makes it challenging to achieve balance in a zero-field space. By performing both forward and reverse measurements at the same location using the opposing coil setup and calculating the difference between the signals, the inductive coupling between coils at the measurement site can theoretically be eliminated. This eliminates the induced potential of the TEM signal, enhancing the induced electromotive force from the formation. As a result, more accurate resistivity values are obtained, detection blind spots are eliminated, and the resolution in shallow TEM exploration is improved. Field experiments were conducted to validate the method on both high-resistivity and low-resistivity anomalies. The results demonstrated that this method effectively identified a high-resistivity corrugated pipe at a depth of 1.2 m and two low-resistivity gas pipelines at a depth of 2 m, thereby essentially eliminating detection blind spots in the shallow subsurface. Full article
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20 pages, 6100 KiB  
Article
Rearview Camera-Based Blind-Spot Detection and Lane Change Assistance System for Autonomous Vehicles
by Yunhee Lee and Manbok Park
Appl. Sci. 2025, 15(1), 419; https://doi.org/10.3390/app15010419 - 4 Jan 2025
Cited by 2 | Viewed by 2298
Abstract
This paper focuses on a method of rearview camera-based blind-spot detection and a lane change assistance system for autonomous vehicles, utilizing a convolutional neural network and lane detection. In this study, we propose a method for providing real-time warnings to autonomous vehicles and [...] Read more.
This paper focuses on a method of rearview camera-based blind-spot detection and a lane change assistance system for autonomous vehicles, utilizing a convolutional neural network and lane detection. In this study, we propose a method for providing real-time warnings to autonomous vehicles and drivers regarding collision risks during lane-changing maneuvers. We propose a method for lane detection to delineate the area for blind-spot detection and for measuring time to collision—both utilized to ascertain the vehicle’s location and compensate for vertical vibrations caused by vehicle movement. The lane detection method uses edge detection on an input image to extract lane markings by employing edge pairs consisting of positive and negative edges. Lanes were extracted through third-polynomial fitting of the extracted lane markings, with each lane marking being tracked using the results from the previous frame detections. Using the vanishing point where the two lanes converge, the camera calibration information is updated to compensate for the vertical vibrations caused by vehicle movement. Additionally, the proposed method utilized YOLOv9 for object detection, leveraging lane information to define the region of interest (ROI) and detect small-sized objects. The object detection achieved a precision of 90.2% and a recall of 82.8%. The detected object information was subsequently used to calculate the collision risk. A collision risk assessment was performed for various objects using a three-level collision warning system that adapts to the relative speed of obstacles. The proposed method demonstrated a performance of 11.64 fps with an execution time of 85.87 ms. It provides real-time warnings to both drivers and autonomous vehicles regarding potential collisions with detected objects. Full article
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14 pages, 1993 KiB  
Article
Deep Learning Models for Anatomical Location Classification in Esophagogastroduodenoscopy Images and Videos: A Quantitative Evaluation with Clinical Data
by Seong Min Kang, Gi Pyo Lee, Young Jae Kim, Kyoung Oh Kim and Kwang Gi Kim
Diagnostics 2024, 14(21), 2360; https://doi.org/10.3390/diagnostics14212360 - 23 Oct 2024
Viewed by 1333
Abstract
Background/Objectives: During gastroscopy, accurately identifying the anatomical locations of the gastrointestinal tract is crucial for developing diagnostic aids, such as lesion localization and blind spot alerts. Methods: This study utilized a dataset of 31,403 still images from 1000 patients with normal findings to [...] Read more.
Background/Objectives: During gastroscopy, accurately identifying the anatomical locations of the gastrointestinal tract is crucial for developing diagnostic aids, such as lesion localization and blind spot alerts. Methods: This study utilized a dataset of 31,403 still images from 1000 patients with normal findings to annotate the anatomical locations within the images and develop a classification model. The model was then applied to videos of 20 esophagogastroduodenoscopy procedures, where it was validated for real-time location prediction. To address instability of predictions caused by independent frame-by-frame assessment, we implemented a hard-voting-based post-processing algorithm that aggregates results from seven consecutive frames, improving the overall accuracy. Results: Among the tested models, InceptionV3 demonstrated superior performance for still images, achieving an F1 score of 79.79%, precision of 80.57%, and recall of 80.08%. For video data, the InceptionResNetV2 model performed best, achieving an F1 score of 61.37%, precision of 73.08%, and recall of 57.21%. These results indicate that the deep learning models not only achieved high accuracy in position recognition for still images but also performed well on video data. Additionally, the post-processing algorithm effectively stabilized the predictions, highlighting its potential for real-time endoscopic applications. Conclusions: This study demonstrates the feasibility of predicting the gastrointestinal tract locations during gastroscopy and suggests a promising path for the development of advanced diagnostic aids to assist clinicians. Furthermore, the location information generated by this model can be leveraged in future technologies, such as automated report generation and supporting follow-up examinations for patients. Full article
(This article belongs to the Special Issue Innovation in Gastrointestinal Endoscopy)
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26 pages, 10600 KiB  
Article
Deep Learning-Based Stopped Vehicle Detection Method Utilizing In-Vehicle Dashcams
by Jinuk Park, Jaeyong Lee, Yongju Park and Yongseok Lim
Electronics 2024, 13(20), 4097; https://doi.org/10.3390/electronics13204097 - 17 Oct 2024
Cited by 1 | Viewed by 3065
Abstract
In complex urban road conditions, stationary or illegally parked vehicles present a considerable risk to the overall traffic system. In safety-critical applications like autonomous driving, the detection of stopped vehicles is of utmost importance. Previous methods for detecting stopped vehicles have been designed [...] Read more.
In complex urban road conditions, stationary or illegally parked vehicles present a considerable risk to the overall traffic system. In safety-critical applications like autonomous driving, the detection of stopped vehicles is of utmost importance. Previous methods for detecting stopped vehicles have been designed for stationary viewpoints, such as security cameras, which consistently monitor fixed locations. However, these methods for detecting stopped vehicles based on stationary views cannot address blind spots and are not applicable from driving vehicles. To address these limitations, we propose a novel deep learning-based framework for detecting stopped vehicles in dynamic environments, particularly those recorded by dashcams. The proposed framework integrates a deep learning-based object detector and tracker, along with movement estimation using the dense optical flow method. We also introduced additional centerline detection and inter-vehicle distance measurement. The experimental results demonstrate that the proposed framework can effectively identify stopped vehicles under real-world road conditions. Full article
(This article belongs to the Special Issue AI Synergy: Vision, Language, and Modality)
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17 pages, 7440 KiB  
Article
Research on Automatic Recharging Technology for Automated Guided Vehicles Based on Multi-Sensor Fusion
by Yuquan Xue, Liming Wang and Longmei Li
Appl. Sci. 2024, 14(19), 8606; https://doi.org/10.3390/app14198606 - 24 Sep 2024
Cited by 1 | Viewed by 1359
Abstract
Automated guided vehicles (AGVs) play a critical role in indoor environments, where battery endurance and reliable recharging are essential. This study proposes a multi-sensor fusion approach that integrates LiDAR, depth cameras, and infrared sensors to address challenges in autonomous navigation and automatic recharging. [...] Read more.
Automated guided vehicles (AGVs) play a critical role in indoor environments, where battery endurance and reliable recharging are essential. This study proposes a multi-sensor fusion approach that integrates LiDAR, depth cameras, and infrared sensors to address challenges in autonomous navigation and automatic recharging. The proposed system overcomes the limitations of LiDAR’s blind spots in near-field detection and the restricted range of vision-based navigation. By combining LiDAR for precise long-distance measurements, depth cameras for enhanced close-range visual positioning, and infrared sensors for accurate docking, the AGV’s ability to locate and autonomously connect to charging stations is significantly improved. Experimental results show a 25% increase in docking success rate (from 70% with LiDAR-only to 95%) and a 70% decrease in docking error (from 10 cm to 3 cm). These improvements demonstrate the effectiveness of the proposed sensor fusion method, ensuring more reliable, efficient, and precise operations for AGVs in complex indoor environments. Full article
(This article belongs to the Collection Advances in Automation and Robotics)
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25 pages, 11489 KiB  
Article
Investigating Blind Spot Design Effects on Drivers’ Cognitive Load with Lane Changing: A Comparative Experiment with Multiple Types of Intelligent Vehicles
by Xiaoye Cui, Yijie Li, Lishengsa Yue, Haoyu Chen and Ziyou Zhou
Appl. Sci. 2024, 14(17), 7570; https://doi.org/10.3390/app14177570 - 27 Aug 2024
Viewed by 2226
Abstract
Lane changing is a frequent traffic accident scenario. To improve the driving safety in lane changing scenarios, the blind spot display of lane changing is increased through human–machine interaction (HMI) interfaces in intelligent vehicles to improve the driver’s rate of risk perception with [...] Read more.
Lane changing is a frequent traffic accident scenario. To improve the driving safety in lane changing scenarios, the blind spot display of lane changing is increased through human–machine interaction (HMI) interfaces in intelligent vehicles to improve the driver’s rate of risk perception with regard to the driving environment. However, blind spot information will increase the cognitive load of drivers and lead to driving distraction. To quantify the coupling relationship between blind spot display and drivers’ cognitive load, we proposed a method to quantify the cognitive load of the driver’s interaction by improving the AttenD algorithm, collecting feature data by carrying out a variety of real-vehicle road-testing experiments on three kinds of intelligent vehicles, and then establishing a model blind spot design and driver cognitive load correlation model using Bayesian Logistic Ordinal Regression (BLOR) and Categorical Boosting (CatBoost). The results show that the blind spot image display can reduce the driver’s cognitive load more effectively as it is closer to the driver, has a larger area, and occupies a higher proportion of the center control screen, especially when it is located in the middle and upper regions of the center control screen. The improved AttenD algorithm is able to quantify the cognitive load of the driver, which can be widely used in vehicle testing, HMI interface development and evaluation. In addition, the analytical framework constructed in this paper can help us to understand the complex impact of HMI in intelligent vehicles and provide optimization criteria for lane change blind spot design. Full article
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34 pages, 11123 KiB  
Article
An Improved Golden Jackal Optimization Algorithm Based on Mixed Strategies
by Yancang Li, Qian Yu, Zhao Wang, Zunfeng Du and Zidong Jin
Mathematics 2024, 12(10), 1506; https://doi.org/10.3390/math12101506 - 11 May 2024
Cited by 3 | Viewed by 2358
Abstract
In an effort to overcome the problems with typical optimization algorithms’ slow convergence and tendency to settle on a local optimal solution, an improved golden jackal optimization technique is proposed. Initially, the development mechanism is enhanced to update the prey’s location, addressing the [...] Read more.
In an effort to overcome the problems with typical optimization algorithms’ slow convergence and tendency to settle on a local optimal solution, an improved golden jackal optimization technique is proposed. Initially, the development mechanism is enhanced to update the prey’s location, addressing the limitation of just relying on local search in the later stages of the algorithm. This ensures a more balanced approach to both algorithmic development and exploration. Furthermore, incorporating the instinct of evading natural predators enhances both the effectiveness and precision of the optimization process. Then, cross-mutation enhances population variety and facilitates escaping from local optima. Finally, the crossbar strategy is implemented to change both the individual and global optimal solutions of the population. This technique aims to decrease blind spots, enhance population variety, improve solution accuracy, and accelerate convergence speed. A total of 20 benchmark functions are employed for the purpose of comparing different techniques. The enhanced algorithm’s performance is evaluated using the CEC2017 test function, and the results are assessed using the rank-sum test. Ultimately, three conventional practical engineering simulation experiments are conducted to evaluate the suitability of IWKGJO for engineering issues. The results obtained demonstrate the beneficial effects of the altered methodology and illustrate that the expanded golden jackal optimization algorithm has superior convergence accuracy and a faster convergence rate. Full article
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21 pages, 5735 KiB  
Article
Advancing Borehole Imaging: A Classification Database Developed via Adaptive Ring Segmentation
by Zhaopeng Deng, Shuangyang Han, Zeqi Liu, Jian Wang and Haoran Zhao
Electronics 2024, 13(6), 1107; https://doi.org/10.3390/electronics13061107 - 18 Mar 2024
Viewed by 1620
Abstract
The use of in-hole imaging to investigate geological structure characteristics is one of the crucial methods for the study of rock mass stability and rock engineering design. The in-hole images are usually influenced by the lighting and imaging characteristics, resulting in the presence [...] Read more.
The use of in-hole imaging to investigate geological structure characteristics is one of the crucial methods for the study of rock mass stability and rock engineering design. The in-hole images are usually influenced by the lighting and imaging characteristics, resulting in the presence of interference noise regions in the images and consequently impacting the classification accuracy. To enhance the analytical efficacy of in-hole images, this paper employs the proposed optimal non-concentric ring segmentation method to establish a new database. This method establishes the transformation function based on the Ansel Adams Zone System and the fluctuation values of the grayscale mean, adjusting the gray-level distribution of images to extract two visual blind spots of different scales. Thus, the inner and outer circles are located with these blind spots to achieve the adaptive acquisition of the optimal ring. Finally, we use the optimal non-concentric ring segmentation method to traverse all original images to obtain the borehole image classification database. To validate the effectiveness of this method, we conduct experiments using various segmentation and classification evaluation metrics. The results show that the Jaccard and Dice of the optimal non-concentric ring segmentation approach are 88.43% and 98.55%, respectively, indicating superior segmentation performance compared to other methods. Furthermore, after employing four commonly used classification models to validate the performance of the new classification database, the results demonstrate a significant improvement in accuracy and macro-average compared to the original database, with the highest increase in accuracy reaching 4.2%. These results fully demonstrate the effectiveness of the proposed optimal non-concentric ring segmentation method. Full article
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31 pages, 24369 KiB  
Article
An Integrated YOLOv5 and Hierarchical Human-Weight-First Path Planning Approach for Efficient UAV Searching Systems
by Ing-Chau Chang, Chin-En Yen, Hao-Fu Chang, Yi-Wei Chen, Ming-Tsung Hsu, Wen-Fu Wang, Da-Yi Yang and Yu-Hsuan Hsieh
Machines 2024, 12(1), 65; https://doi.org/10.3390/machines12010065 - 16 Jan 2024
Cited by 4 | Viewed by 2224
Abstract
Because the average number of missing people in our country is more than 20,000 per year, determining how to efficiently locate missing people is important. The traditional method of finding missing people involves deploying fixed cameras in some hotspots to capture images and [...] Read more.
Because the average number of missing people in our country is more than 20,000 per year, determining how to efficiently locate missing people is important. The traditional method of finding missing people involves deploying fixed cameras in some hotspots to capture images and using humans to identify targets from these images. However, in this approach, high costs are incurred in deploying sufficient cameras in order to avoid blind spots, and a great deal of time and human effort is wasted in identifying possible targets. Further, most AI-based search systems focus on how to improve the human body recognition model, without considering how to speed up the search in order to shorten the search time and improve search efficiency, which is the aim of this study. Hence, by exploiting the high-mobility characteristics of unmanned aerial vehicles (UAVs), this study proposes an integrated YOLOv5 and hierarchical human-weight-first (HWF) path planning framework to serve as an efficient UAV searching system, which works by dividing the whole searching process into two levels. At level one, a searching UAV is dispatched to a higher altitude to capture images, covering the whole search area. Then, the well-known artificial intelligence model YOLOv5 is used to identify all persons in the captured images and compute corresponding weighted scores for each block in the search area, according to the values of the identified human bodies, clothing types, and clothing colors. At level two, the UAV lowers its altitude to sequentially capture images for each block, in descending order according to its weighted score at level one, and it uses the YOLOv5 recognition model repeatedly until the search target is found. Two improved search algorithms, HWFR-S and HWFR-D, which incorporate the concept of the convenient visit threshold and weight difference, respectively, are further proposed to resolve the issue of the lengthy and redundant flight paths of HWF. The simulation results suggest that the HWF, HWFR-S, and HWFR-D search algorithms proposed in this study not only effectively reduce the length of a UAV’s search path and the number of search blocks but also decrease the search time required for a UAV to locate the search target, with a much higher search accuracy than the two traditional search algorithms. Moreover, this integrated YOLOv5 and HWF framework is implemented and tested in a real scenario to demonstrate its capability in enhancing the efficiency of a search and rescue operation. Full article
(This article belongs to the Special Issue Dynamics and Control of UAVs)
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4 pages, 1818 KiB  
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Immunohistochemistry in an Adult Case of Bitot’s Spots Caused by Vitamin A Deficiency
by Hideki Fukuoka, Norihiko Yokoi and Chie Sotozono
Diagnostics 2023, 13(24), 3676; https://doi.org/10.3390/diagnostics13243676 - 15 Dec 2023
Cited by 2 | Viewed by 2974
Abstract
Bitot’s spots (BS) are the buildup of superficially located keratin in the conjunctiva and are early indicators of vitamin A deficiency (VAD), primarily due to malnutrition and malabsorption, thus leading to xerophthalmia. BS are particularly prevalent in developing countries, and their presence necessitates [...] Read more.
Bitot’s spots (BS) are the buildup of superficially located keratin in the conjunctiva and are early indicators of vitamin A deficiency (VAD), primarily due to malnutrition and malabsorption, thus leading to xerophthalmia. BS are particularly prevalent in developing countries, and their presence necessitates prompt vitamin A supplementation to avert blindness, with the immunohistochemical characteristics of BS aiding in understanding the extent of epithelial abnormalities and the efficacy of vitamin A supplementation. We describe the case of a 34-year-old male with persistent BS despite extensive vitamin A supplementation and topical treatments who underwent surgical excision of the BS followed by amniotic membrane transplantation, thus resulting in symptom relief and epithelialization, with no recurrence observed during follow-up. Histopathologic and immunohistochemical evaluations revealed expression of keratinization-related proteins, along with an absence of mucin-5AC-positive cells, suggesting impaired differentiation into goblet cells due to VAD. This case highlights the potential age-related disparity in the efficacy of vitamin A supplementation, emphasizing the need for early detection and a multidisciplinary approach in the management of VAD, especially in young adults. The favorable outcome of surgical intervention highlights its viability in the management of persistent BS and encourages further investigation to optimize therapeutic strategies for VAD-related ocular manifestations. Full article
(This article belongs to the Special Issue Diagnosis, Treatment and Management of Eye Diseases)
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13 pages, 1174 KiB  
Article
Complementary Role of CEUS and CT/MR LI-RADS for Diagnosis of Recurrent HCC
by Mei-Qing Cheng, Hui Huang, Si-Min Ruan, Ping Xu, Wen-Juan Tong, Dan-Ni He, Yang Huang, Man-Xia Lin, Ming-De Lu, Ming Kuang, Wei Wang, Shao-Hong Wu and Li-Da Chen
Cancers 2023, 15(24), 5743; https://doi.org/10.3390/cancers15245743 - 7 Dec 2023
Cited by 8 | Viewed by 1986
Abstract
Purpose: We retrospectively compared the diagnostic performance of contrast-enhanced ultrasonography (CEUS) and contrast-enhanced computer tomography–magnetic resonance imaging (CT/MRI) for recurrent hepatocellular carcinoma (HCC) after curative treatment. Materials and methods: After curative treatment with 421 ultrasound (US) detected lesions, 303 HCC patients underwent both [...] Read more.
Purpose: We retrospectively compared the diagnostic performance of contrast-enhanced ultrasonography (CEUS) and contrast-enhanced computer tomography–magnetic resonance imaging (CT/MRI) for recurrent hepatocellular carcinoma (HCC) after curative treatment. Materials and methods: After curative treatment with 421 ultrasound (US) detected lesions, 303 HCC patients underwent both CEUS and CT/MRI. Each lesion was assigned a Liver Imaging Reporting and Data System (LI-RADS) category according to CEUS and CT/MRI LI-RADS. Receiver-operating characteristic (ROC) curves were computed to determine the optimal diagnosis algorithms for CEUS, CT and MRI. The diagnostic accuracy, sensitivity, specificity, and area under the curve (AUC) were compared between CEUS and CT/MRI. Results: Among the 421 lesions, 218 were diagnosed as recurrent HCC, whereas 203 lesions were diagnosed as benign. In recurrent HCC, CEUS detected more arterial hyperenhancement (APHE) and washout than CT and more APHE than MRI. CEUS yielded better diagnostic performance than CT (AUC: 0.981 vs. 0.958) (p = 0.024) comparable diagnostic performance to MRI (AUC: 0.952 vs. 0.933) (p > 0.05) when using their optimal diagnostic criteria. CEUS missed 12 recurrent HCCs, CT missed one, and MRI missed none. The detection rate of recurrent HCC on CEUS (94.8%, 218/230) was lower than that on CT/MRI (99.6%, 259/260) (p = 0.001). Lesions located on the US blind spots and visualization score C would hinder the ability of CEUS to detect recurrent HCC. Conclusion: CEUS demonstrated excellent diagnostic performance but an inferior detection rate for recurrent HCC. CEUS and CT/MRI played a complementary role in the detection and characterization of recurrent HCC. Full article
(This article belongs to the Special Issue Radiology for Diagnosis and Treatment of Liver Cancer)
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