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11 pages, 531 KB  
Article
πForce—Repeatability and Reliability of Peak Force and Rate of Force Development in a Portable Multi-Exercise Device
by Ricardo Pimenta and Abel Pimenta
Muscles 2025, 4(3), 36; https://doi.org/10.3390/muscles4030036 - 1 Sep 2025
Abstract
Isometric strength is widely used to monitor training adaptations, assess neuromuscular fatigue, and play a critical role in the maintenance of muscle health. This study assessed repeatability (intra-session) and reliability (inter-session) of a force production machine in different exercises: Isometric Mid-Thigh Pull (IMTP), [...] Read more.
Isometric strength is widely used to monitor training adaptations, assess neuromuscular fatigue, and play a critical role in the maintenance of muscle health. This study assessed repeatability (intra-session) and reliability (inter-session) of a force production machine in different exercises: Isometric Mid-Thigh Pull (IMTP), Knee Flexion (KF) at 30°, and Seated Calf Raise (SCR). Parameters measured included Peak Force (PF), RFD at 0–50, 0–100, 0–150, 0–200, 50–100, 100–150 and 150–200 ms. Thirty male individuals (IMTP = 30; KF = 11 and SCR = 30) participated (age: 20.6 ± 3.6 years, mass: 75.3 ± 7.5 kg, height: 1.80 ± 0.64 m). Repeatability and reliability were calculated for bilateral PF and RFD for IMTP and SCR, and unilateral for KF. PF demonstrated good to excellent repeatability in all exercises: IMTP (ICC = 0.93), KF (left: ICC = 0.98; right: ICC = 0.97), SCR (ICC = 0.84). RFD displayed poor to good repeatability in IMTP (ICC = 0.45–0.87) and SCR (ICC = 0.40–0.85), moderate to excellent repeatability in KF (left: ICC = 0.53–0.96; right: ICC = 0.61–0.92). PF reliability was excellent in IMTP (ICC = 0.93) and KF (left: ICC = 0.99; right: ICC = 0.97), and moderate in SCR (ICC = 0.64). RFD reliability was moderate to excellent in IMTP (ICC = 0.58–0.94), poor to good in SCR (ICC = 0.13–0.64), and poor to excellent in KF (left: ICC = 0.33–0.96; right: ICC = −0.19–0.95). This study shows that portable dynamometry can measure maximal and explosive strength in different exercises, demonstrating good reliability for most parameters in IMTP and KF. Full article
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13 pages, 1534 KB  
Article
Differences in Body Composition and Lower Limb Strength Between Novice and Amateur Marathon Runners: A Cross-Sectional Study
by Tianxin Shi, Qingzhao Shi, Shuang Ren, Xiaorui Huang, Jun Ren, Xin Gao and Jingxian Zhu
Sports 2025, 13(9), 287; https://doi.org/10.3390/sports13090287 - 26 Aug 2025
Viewed by 333
Abstract
This study compared the body composition and strength of the lower extremity parameters between novice runners (NRs) and amateur marathon runners (AMRs). A total of 50 NRs (33.84 ± 4.32 years) and 50 AMRs (33.36 ± 5.55 years) were analyzed cross-sectionally. Bioelectrical impedance [...] Read more.
This study compared the body composition and strength of the lower extremity parameters between novice runners (NRs) and amateur marathon runners (AMRs). A total of 50 NRs (33.84 ± 4.32 years) and 50 AMRs (33.36 ± 5.55 years) were analyzed cross-sectionally. Bioelectrical impedance analysis measured body composition parameters, and isokinetic testing assessed knee muscle strength. The results showed that compared to AMRs, NRs had lower fat-free mass (FFM), skeletal muscle mass (SMM), and total body water (TBW) (−15, −12, and −5%; all p < 0.01) but higher body fat percentage (PBF) and visceral fat area (VFA) (+27 and +32%; both p < 0.01). They also had 6% lower knee extensor (KE) strength and 31% lower knee flexor (KF) strength on the dominant legs (DLs) and 14% lower KF strength on the non-dominant legs (NDLs). In addition, their hamstring–quadriceps ratio (H: Q) was 24% lower on the DLs and 9% lower on the NDLs. The NRs exhibited significant negative correlations between PBF, VFA, and knee muscle strength (r = −0.54 to −0.42, p < 0.01), while the AMRs had significant negative correlations only for PBF (r = −0.59 to −0.57, p < 0.001). In conclusion, the NRs exhibited lower FFM and TBW, higher PBF and VFA, and reduced muscle strength. In contrast, the AMRs exhibited the opposite pattern. These findings suggest that NRs with elevated body fat (BF) indicators should prioritize fat reduction and performance enhancement, while those with lower muscle mass require targeted programs to increase muscle capacity and joint stability. This approach may advance them toward the level of AMRs. Future studies should adopt longitudinal designs to explore how training interventions influence the physiological adaptations observed in runners at different experience levels. Full article
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16 pages, 3466 KB  
Article
Direction-Dependent Limb Asymmetries in Female Lateral Jumps: A Ground Reaction Force and Knee Torque Study
by Michalina Błażkiewicz, Aleksandra Malec, Marta Trawczyńska, Michał Skalik and Jacek Wąsik
Appl. Sci. 2025, 15(16), 9150; https://doi.org/10.3390/app15169150 - 20 Aug 2025
Viewed by 260
Abstract
Background: Movement symmetry in the lower limbs is critical for biomechanical efficiency, injury prevention, and athletic performance. Lateral (sideways) jumping challenges force production and control in the frontal plane and provide a unique assessment of neuromuscular coordination that may not be detected through [...] Read more.
Background: Movement symmetry in the lower limbs is critical for biomechanical efficiency, injury prevention, and athletic performance. Lateral (sideways) jumping challenges force production and control in the frontal plane and provide a unique assessment of neuromuscular coordination that may not be detected through sagittal-plane tasks such as running or vertical jumping. This study aimed to evaluate limb asymmetries in isometric knee muscle torque and ground reaction forces (GRFs) during lateral jumps in healthy young women, using the Symmetry Index (SI) to quantify differences between limbs. Methods: Twenty right-limb dominant females (mean age: 20.65 ± 4.51 years) participated in the study. Isometric torque of the knee flexors and extensors was measured using a dynamometric testing station. Lateral jumps were performed onto dual force platforms, with GRF components (vertical (PD), anterior–posterior (AP), mediolateral (ML)) recorded separately for rightward and leftward jumps. SI was calculated for all parameters to determine side-to-side asymmetries, and paired Student’s t-tests were used for statistical comparisons. Results: Right-limb dominance was evident in both knee flexor and extensor torque. Significant asymmetries were observed across all GRF components, varying with jump direction. The trailing limb in each jump direction typically generated greater propulsion forces. In lateral jumps, the trailing limb is generally the leg positioned opposite to the direction of travel, playing a primary role in generating propulsion and absorbing forces during take-off. SI values revealed both inter-individual variability and consistent direction-dependent asymmetry patterns. Conclusions: The or-posterior and vertical components, with greater loading on the dominant leg. Muscle torque measurements also revealed imbalances, with flexors showing more symmetry than extensors. These findings underline the importance of assessing load symmetry to prevent injury and guide rehabilitation. Full article
(This article belongs to the Special Issue Research of Sports Medicine and Health Care: Second Edition)
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20 pages, 2173 KB  
Article
Pain State Classification of Stiff Knee Joint Using Electromyogram for Robot-Based Post-Fracture Rehabilitation Training
by Yang Zheng, Dimao He, Yuan He, Xiangrui Kong, Xiaochen Fan, Min Li, Guanghua Xu and Jichao Yin
Sensors 2025, 25(16), 5142; https://doi.org/10.3390/s25165142 - 19 Aug 2025
Viewed by 520
Abstract
Knee joint stiffness occurs and severely limits its range of motion (ROM) after facture around the knee. During mobility training, knee joints need to be flexed to the maximum angle position (maxAP) that can induce pain at an appropriate level in order to [...] Read more.
Knee joint stiffness occurs and severely limits its range of motion (ROM) after facture around the knee. During mobility training, knee joints need to be flexed to the maximum angle position (maxAP) that can induce pain at an appropriate level in order to pull apart intra-articular adhesive structures while avoiding secondary injuries. However, the maxAP varies with training and is mostly determined by the pain level of patients. In this study, the feasibility of utilizing electromyogram (EMG) activities to detect maxAP was investigated. Specifically, the maxAP detection was converted into a binary classification between pain level three of the numerical rating scales (pain) and below (painless) according to clinical requirements. Firstly, 12 post-fracture patients with knee joint stiffness participated in Experiment I, with a therapist performing routine mobility training and EMG signals being recorded from knee flexors and extensors. The results showed that the extracted EMG features were significantly different between the pain and painless states. Then, the maxAP estimation performance was tested on a knee rehabilitation robot in Experiment II, with another seven patients being involved. The support vector machine and random forest models were used to classify between pain and painless states and obtained a mean accuracy of 87.90% ± 4.55% and 89.10% ± 4.39%, respectively, leading to an average estimation bias of 6.5° ± 5.1° and 4.5° ± 3.5°. These results indicated that the pain-induced EMG can be used to accurately classify pain states for the maxAP estimation in post-fracture mobility training, which can potentially facilitate the application of robotic techniques in fracture rehabilitation. Full article
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15 pages, 403 KB  
Article
The Effects of Pedaling-Based Progressive Resistance Training on Range of Motion, Muscle Strength, and Physical Function in Female Patients with Total Knee Arthroplasty: Single-Blind Randomized Controlled Trial
by Jungae An, Junseok Seo and Byoung-Hee Lee
Medicina 2025, 61(8), 1441; https://doi.org/10.3390/medicina61081441 - 10 Aug 2025
Viewed by 548
Abstract
Background and Objectives: Total knee arthroplasty (TKA) is an effective solution for pain relief and functional recovery in patients with end-stage osteoarthritis. However, stiffness of the knee, limited range of motion, and weakened muscle strength are challenges of postoperative rehabilitation. This study [...] Read more.
Background and Objectives: Total knee arthroplasty (TKA) is an effective solution for pain relief and functional recovery in patients with end-stage osteoarthritis. However, stiffness of the knee, limited range of motion, and weakened muscle strength are challenges of postoperative rehabilitation. This study investigated the effects of a pedaling-based progressive resistance training (PPRT) program on range of motion, muscle strength, physical function, and gait in patients who had undergone TKA. Materials and Methods: A total of 48 female patients (aged 65–79) who underwent TKA participated in the study and were randomly assigned to either the PPRT group (n = 24) or the control group (n = 24). The PPRT group performed the training for 60 min per session, twice a day, five days a week, for four weeks. The primary outcomes were the muscle strength and range of motion (ROM) of the knee. Secondary outcomes included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Timed Up and Go (TUG) test. Results: There was a significant time × group interaction effect in all the quadriceps strength values (p < 0.05), with a moderate to large effect size (η2p = 0.142–0.390). The PPRT group showed a smaller decrease in knee flexor and extensor strength and a greater improvement in knee flexion range of motion compared with the control group (p < 0.05). The WOMAC index and TUG time were also significantly improved compared with the control group (p < 0.05). In the time × group interaction, a significant effect was shown in WOMAC pain, physical function, and total score (p < 0.05) with a moderate to large effect size (η2p = 0.099–0.196). TUG time also showed a significant time × group interaction (p < 0.05) with a moderating effect (η2p = 0.0840). Conclusions: This study suggests that pedaling-based progressive resistance training helps maintain knee flexor and extensor strength as well as improves range of motion and physical function in patients following TKA and can be proposed as effective training for post-TKA rehabilitation. Full article
(This article belongs to the Section Sports Medicine and Sports Traumatology)
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9 pages, 284 KB  
Article
Can Conditioning Activity with Blood Flow Restriction Impact Neuromuscular Performance and Perceptual Responses to Exercise?
by Robson Conceição Silva, Leandro Lima Sousa, Hugo de Luca Correa, Thailson Fernandes Silva, Lucas de Souza Martins, Pedro Felix, Martim Bottaro, Denis César Leite Vieira and Carlos Ernesto
Sports 2025, 13(8), 243; https://doi.org/10.3390/sports13080243 - 24 Jul 2025
Viewed by 383
Abstract
Low-load conditioning activity with blood flow restriction has been addressed as an efficient method to enhance an individual’s performance during their main exercise activity. However, the optimal degree of blood flow restriction remains unclear. Therefore, this study investigated the acute effects of low-load [...] Read more.
Low-load conditioning activity with blood flow restriction has been addressed as an efficient method to enhance an individual’s performance during their main exercise activity. However, the optimal degree of blood flow restriction remains unclear. Therefore, this study investigated the acute effects of low-load conditioning activity with different degrees of blood flow restriction on muscle strength, power, and perceived exertion. Twenty recreationally trained men (20.9 ± 2.3 years) participated in a randomized crossover design including three conditions: control, low-load blood flow restriction at 50%, and 75% of total arterial occlusion pressure. Participants performed squats (three sets of ten reps) followed by isokinetic assessments of the knee flexor and extensor performance at 7 and 10-min post-exercise. The session rating of perceived exertion (SRPE) was recorded 30 min after each session. No significant effects were observed for condition, time, or their interaction on peak torque, total work, or average power (p < 0.05). However, SRPE was significantly higher in the 75% BFR condition compared to both the 50% BFR and control conditions (p < 0.05), with no difference between the 50% BFR and control. These findings suggest that low-load conditioning activity with blood flow restriction does not acutely enhance neuromuscular performance. However, a higher degree of restriction increases perceived exertion. Full article
(This article belongs to the Special Issue Neuromechanical Adaptations to Exercise and Sports Training)
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17 pages, 1123 KB  
Article
Effects of a Single Session of Robot-Assisted Gait Training vs. Aquatic Therapy, Immersion in Water, and Supported Standing on Post-Immediate Knee Musculoskeletal Conditions in Children with Cerebral Palsy: A Case Report
by Andrés Ramiro Ferrando, Anna Arnal-Gómez, Sara Cortés-Amador, Noelia Gimeno Muñoz, Luis Beltrán Alós and Esther Mur-Gimeno
Appl. Sci. 2025, 15(15), 8203; https://doi.org/10.3390/app15158203 - 23 Jul 2025
Viewed by 488
Abstract
Background: Aquatic therapy (AT), immersion in hot water, and supported standing are frequently used to manage spasticity, contractures, and joint retractions in children with cerebral palsy (CP). Recently, the use of exoskeletons has been offering a new treatment option for severe CP. This [...] Read more.
Background: Aquatic therapy (AT), immersion in hot water, and supported standing are frequently used to manage spasticity, contractures, and joint retractions in children with cerebral palsy (CP). Recently, the use of exoskeletons has been offering a new treatment option for severe CP. This study aimed to compare the post-immediate effects of four treatments on spasticity, range of motion, and the heart rate of children with severe CP. Methods: Three children with spastic CP (levels IV and V GMFCS) received a single 30-min session in consecutive weeks of robot-assisted gait training (RAGT), AT, supported standing, and immersion in hot water. Post-immediate assessments included knee flexor spasticity (modified Ashworth scale, MAS, and modified Tardieu scale, MTS); knee range of motion (ROM, in degrees (°)); and heart rate (HR). Results: AT and supported standing induced greater reductions in spasticity based on MAS scores. RAGT demonstrated superior spasticity reduction using MTS and yielded the greatest improvement in popliteal angle (mean increase: 27°). AT and RAGT induced a 14 beats-per-minute change in HR, indicating moderate cardiovascular engagement. Conclusions: RAGT appears particularly effective in improving spasticity and ROM in children with severe CP. Nonetheless, conventional treatments still offer an effective option when addressing spasticity. Full article
(This article belongs to the Section Applied Biosciences and Bioengineering)
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17 pages, 944 KB  
Article
Lower Limb Muscle Strength Matters: Effect of Relative Isometric Strength on Countermovement and Rebound Jump Performance in Elite Youth Female Soccer Players
by Jack Fahey, Paul Comfort and Nicholas Joel Ripley
Muscles 2025, 4(3), 23; https://doi.org/10.3390/muscles4030023 - 10 Jul 2025
Viewed by 529
Abstract
Background: Expression of maximal and rapid force in the hip, knee, and plantar flexors is important for athletic performance in female soccer. This study was designed to determine the effect of relative isometric strength in the isometric mid-thigh pull (IMTP) on countermovement jump [...] Read more.
Background: Expression of maximal and rapid force in the hip, knee, and plantar flexors is important for athletic performance in female soccer. This study was designed to determine the effect of relative isometric strength in the isometric mid-thigh pull (IMTP) on countermovement jump (CMJ) and rebound jump (CMJ-R) performance in female youth soccer players. Methods: Ninety-six female soccer players (age: 14.1 ± 2.3 years, height: 160.5 ± 9.7 cm, mass: 55.0 ± 10.3 kg) completed three trials of the IMTP, CMJ, and CMJ-R using force plates. Players were categorized as stronger (top quartile, n = 19) and weaker players (bottom quartile, n = 23) based on IMTP relative net peak force. One-way Bayesian independent t-tests were performed between stronger and weaker players. Results: Very large difference in lower limb strength between groups (g = 5.05). Moderate to very strong evidence to support that stronger players had greater countermovement depth and time to take-off with similar jump heights than weaker players. Strong evidence was observed for CMJ-R height, with stronger players falling from a greater height and executing similar ground contact times compared to weaker players. Conclusions: Relative strength has implications for CMJ-R, highlighting the importance of developing relative strength in hip, knee, and plantar extensors. Full article
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12 pages, 1184 KB  
Article
Does Proprioceptive Neuromuscular Facilitation-Based Hamstring Stretching Influence Deep Cervical Flexor Muscle Endurance?
by Altay Kosova and Omer Osman Pala
Life 2025, 15(7), 1019; https://doi.org/10.3390/life15071019 - 26 Jun 2025
Viewed by 824
Abstract
Aim: To assess the acute effects of proprioceptive neuromuscular facilitation (PNF), stretching was applied to the hamstring muscles to evaluate deep cervical flexor endurance. Potential variables correlating with endurance adaptations were examined. Methods: This randomized controlled trial performed between September 2023 and June [...] Read more.
Aim: To assess the acute effects of proprioceptive neuromuscular facilitation (PNF), stretching was applied to the hamstring muscles to evaluate deep cervical flexor endurance. Potential variables correlating with endurance adaptations were examined. Methods: This randomized controlled trial performed between September 2023 and June 2024 included healthy female university students aged 18–25 years. Participants were randomly assigned to either the control or the PNF group. Variables included age, height, weight, body mass index, Beighton score, hamstring flexibility, and deep cervical flexor muscle endurance; correlations between changes in hamstring flexibility and DCF endurance were explored. Hamstring flexibility was assessed using the Passive Knee Extension Test, and deep cervical flexor endurance was assessed using the Cranio-Cervical Flexion Test. The PNF group received hold–relax exercises while controls did not receive any intervention. Results: The study included 32 control participants and 32 individuals in the PNF group. The PNF group was marginally but significantly older than the control group [22 (21–23) vs. 21 (21–22); p = 0.038]. At baseline, the PNF group showed greater hamstring flexibility (p = 0.010). Both groups showed significant improvements in hamstring flexibility (p < 0.001 for both), but the improvement in the PNF recipients was far greater (p < 0.001). Regarding deep neck flexor endurance, no significant difference was observed between the groups at baseline (p = 0.958) or in final measurements (p = 0.244), although both groups showed significant improvements from baseline (p < 0.001 for both). There were no significant correlations between the change in deep neck flexor endurance and any of the examined variables. Conclusions: Our study found that a single session of PNF stretching significantly improved hamstring flexibility but did not immediately enhance deep neck flexor endurance. This emphasizes the need for further research into longer-term interventions to assess whether interventions on hamstring flexibility can improve cervical function. Full article
(This article belongs to the Special Issue Feature Paper in Physiology and Pathology: 2nd Edition)
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16 pages, 622 KB  
Article
Relationship Between Intermuscular Synchronization of Upper Leg Muscles and Training Level in Karate Kumite Practitioners
by Velimir Jeknić, Milivoj Dopsaj and Nenad Koropanovski
J. Funct. Morphol. Kinesiol. 2025, 10(3), 234; https://doi.org/10.3390/jfmk10030234 - 20 Jun 2025
Viewed by 433
Abstract
Objectives: This study aimed to compare the involuntary stimulated neuromuscular response of thigh muscles in karate subgroups and non-athletes. We investigated whether karate training creates neuromuscular adaptations and if the synchronization of knee flexor and extensor muscles in karate practitioners is level-dependent. [...] Read more.
Objectives: This study aimed to compare the involuntary stimulated neuromuscular response of thigh muscles in karate subgroups and non-athletes. We investigated whether karate training creates neuromuscular adaptations and if the synchronization of knee flexor and extensor muscles in karate practitioners is level-dependent. Methods: The study included 7 elite karate athletes (KE), 14 sub-elite karate athletes (KSE), 16 individuals with basic karate training (KB), and 14 non–athletes (NA). Tensiomyographic (TMG) measurements were obtained from the rectus femoris, vastus medialis, vastus lateralis, biceps femoris, and semitendinosus muscles. Indexes of Intermuscular Synchronization (IIS) were calculated for contraction time (Tc), total contraction time (TcT), and rate of muscle tension development (RMTD) as variables for the observed muscles of a given muscle group (extensors of the dominant leg, flexors of the dominant leg, extensors of the non-dominant leg, and flexors of the non-dominant leg). Results: Statistically significant differences were observed in the intermuscular synchronization indexes between karate experience levels and non-athletes. Compared to non-athletes, elite (KE), sub-elite (KSE), and beginner karateka (KB) all demonstrated shorter contraction time indexes in dominant knee extensors (p = 0.042, 0.040, and 0.013, respectively). In the non-dominant flexors, KE exhibited significantly better synchronization than KSE (p = 0.001), KB (p = 0.033), and NA (p = 0.002). For the total contraction time index, both KSE and KB outperformed NA in dominant extensors (p = 0.023 and p = 0.008), while KE showed superiority in non-dominant extensors and flexors compared to all other groups (p-values ranging from 0.002 to 0.038). Significant RMTD differences were found in the dominant leg between KE and KSE (p = 0.036) and KE and KB (p = 0.001), as well as in the non-dominant leg between KE and KB (p = 0.011) and KE and NA (p = 0.025). These findings were accompanied by statistical powers exceeding 0.80 in most cases, underscoring the robustness of the observed differences. Conclusions: These findings highlight that muscle coordination patterns, as revealed through non-invasive TMG-based indexes, are sensitive to training level and laterality in karate practitioners. Importantly, elite athletes demonstrated more synchronized activation in key muscle groups, suggesting a neuromuscular adaptation specific to high-level combat sports. From a biomechanical perspective, improved intermuscular synchronization may reflect optimized neural strategies for stability, speed, and efficiency—key components in competitive karate. Thus, this method holds promise not only for performance diagnostics but also for refining individualized training strategies in combat sports and broader athletic contexts. Full article
(This article belongs to the Special Issue Innovative Approaches in Monitoring Individual Sports)
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13 pages, 959 KB  
Article
Ipsilateral Repeated Bout Effect Across Heterologous Muscle Groups: Eccentric Knee Extensor Conditioning Enhances Elbow Flexor Recovery in Young Women
by Fu-Shun Hsu, Chung-Chan Hsieh, Chia-Yu Tang, Chang-Chi Lai, Yu-Jui Li, Yun-Chung Tseng and Szu-Kai Fu
Life 2025, 15(6), 919; https://doi.org/10.3390/life15060919 - 6 Jun 2025
Viewed by 949
Abstract
This study investigated whether prior eccentric exercise of knee extensors could attenuate muscle damage in ipsilateral elbow flexors, supporting the presence of an ipsilateral repeated bout effect (IL-RBE) across heterogeneous muscle groups. Sixteen young women were randomized into an intervention group (NL/NU) and [...] Read more.
This study investigated whether prior eccentric exercise of knee extensors could attenuate muscle damage in ipsilateral elbow flexors, supporting the presence of an ipsilateral repeated bout effect (IL-RBE) across heterogeneous muscle groups. Sixteen young women were randomized into an intervention group (NL/NU) and a control group (C/NU). The NL/NU group performed eccentric knee extensor exercise 14 days before elbow flexor eccentric loading. Compared to the C/NU group, the NL/NU group exhibited an earlier return to baseline in muscle stiffness (D3: NL/NU = 1.14 ± 0.05 vs. Pre = 0.96 ± 0.03 m/s), joint release angle at 30° (D3: NL/NU = 22.79 ± 1.02 vs. Pre = 24.46 ± 0.87°), and joint release angle at 45° (D2: NL/NU = 37.75 ± 1.38 vs. Pre = 38.83 ± 0.87°), indicating a faster recovery trend in these specific neuromuscular and morphological measures. These results suggest that prior remote eccentric loading induces systemic and neuromuscular adaptations, facilitating improved functional recovery. The findings expand IL-RBE applicability to heterologous muscles within the same limb and support its integration into training and rehabilitation protocols. Full article
(This article belongs to the Special Issue Advanced Research in Exercise Medicine)
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15 pages, 755 KB  
Article
Role of Electrically Evoked Muscle Hypertrophy on Spasticity in Persons with Spinal Cord Injury
by Momal A. Wasim, Ahmad M. Alazzam and Ashraf S. Gorgey
J. Clin. Med. 2025, 14(11), 3972; https://doi.org/10.3390/jcm14113972 - 4 Jun 2025
Viewed by 754
Abstract
Study Design: Pilot randomized clinical trial. Objective: To examine the effect of electrically evoked muscle hypertrophy on indices of spasticity, as measured by Biodex after spinal cord injury (SCI). Setting: Medical research center. Methods: Thirteen males with chronic SCI were [...] Read more.
Study Design: Pilot randomized clinical trial. Objective: To examine the effect of electrically evoked muscle hypertrophy on indices of spasticity, as measured by Biodex after spinal cord injury (SCI). Setting: Medical research center. Methods: Thirteen males with chronic SCI were randomized into sixteen weeks of either surface neuromuscular resistance training (NMES-RT) + testosterone treatment (TT) (n = 7) or a TT-only group (n = 6). A Biodex isokinetic dynamometer was used to measure knee extensor and flexor muscle spasticity at the beginning (baseline; BL) and at the end (post-intervention; PI) of 16 weeks. The passive tension of the right knee extensor and flexor muscle groups were evaluated at angles of 5°, 30°, 60°, 90°, 180°, and 270° per second (sec). Dual energy X-ray absorptiometry and magnetic resonance imaging were used to measure leg lean mass and thigh muscle cross-sectional areas (CSAs). Results: Robust muscle hypertrophy was noted in leg lean mass [11%, p = 0.023] as well as whole thigh [17%, p = 0.001] and knee extensor muscle [28%, p = 0.001] CSAs in the NMES-RT+TT compared to the TT-only group. There was no difference in extensor or flexor spasticity between the NMES-RT+TT or TT-only groups at different angular velocities following 16 weeks of intervention. Collapsing the extensor passive torques indicated an (24–28%) increase (p < 0.004) in response to angular velocities at BL and following PI measurements [180 deg/sec (23%; p = 0.03) and 270 deg/sec (32%; p = 0.009)] compared to 5 deg/sec. The extensor slope showed a non-significant (p > 0.05) decrease of 15–28% across all angular velocities. The catch-AB slopes were non-significantly lower in the TT-only group compared to the NMES-RT+TT at higher speeds [90 deg/sec and 270 deg/sec] and attained a trend towards lower passive torque at 180 deg/sec [180 deg/sec: 15.5%, p = 0.05]. Conclusions: Evoking skeletal muscle hypertrophy did not increase spasticity indices at different angular velocities following sixteen weeks of NMES-RT+TT or TT in persons with chronic SCI. Augmenting muscle hypertrophy is likely to attenuate the hyper reflexive slope of the extensor spasticity. The findings may suggest that evoking muscle hypertrophy following NMES-RT does not increase indices of spasticity after SCI. The clinical implications are highly important in managing spasticity after SCI. Full article
(This article belongs to the Section Clinical Rehabilitation)
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13 pages, 245 KB  
Article
Differences in Strength, Muscle Work, and Hamstring/Quadriceps Ratio in Professional and Junior Elite Basketball Players According to Sex
by Raúl Coto Martín, Néstor Pérez Mallada, María Jesús Martínez Beltrán, Lucía Cuéllar Marín, Pablo José Borrás Luján, Oscar Otín Arroyo, María Ana Sáenz-Nuño and Juan Manuel Arribas-Marín
J. Funct. Morphol. Kinesiol. 2025, 10(2), 204; https://doi.org/10.3390/jfmk10020204 - 2 Jun 2025
Viewed by 1035
Abstract
Background: Anterior cruciate ligament (ACL) injury is more prevalent in young athletes and women. A deficit of knee flexor strength and a H/Q strength ratio below 0.6 in athletes are risk factors. Therefore, the main objective of this study is to determine if [...] Read more.
Background: Anterior cruciate ligament (ACL) injury is more prevalent in young athletes and women. A deficit of knee flexor strength and a H/Q strength ratio below 0.6 in athletes are risk factors. Therefore, the main objective of this study is to determine if there are differences in the strength of the knee musculature, joint work, and H/Q ratio between professional and junior elite basketball players and sexes, since there are differences in the incidence of ACL injuries between these groups. Methods: Forty-three professional (27 male and 16 female) and 42 junior elite (28 male and 14 female) basketball players were evaluated. Dynamometric knee flexion and extension measurements were performed on both lower limbs at three angular velocities: 30°/s, 120°/s, and 180°/s. Concentric knee flexion and extension strength variables were measured in Newtons, the strength ratio between flexors and extensors in H/Q ratio, and muscle work (product of force times displacement) in Joules. Comparisons of the measured variables were made between categories and sexes. Results: Significant differences (p < 0.05) were found between categories (professional and junior) in all measured strength parameters as well as in joint work. No differences were found between categories in the H/Q ratios. Significant differences (p < 0.05) were found between sexes in most measured strengths and joint work. However, no differences were found in most of the H/Q ratios. Female basketball players have lower values of strength and muscle work than male players, however, in the H/Q ratio data there are no differences between the two groups. The same occurs between junior and professional athletes. Conclusions: The authors conclude that flexor and extensor strength values should be analyzed in isolation and not in terms of the H/Q ratio. Full article
10 pages, 1243 KB  
Case Report
A Case of Rheumatoid Arthritis Complicated by Compression of the Popliteal Artery and Tibial Nerve Due to an Organized Hematoma in the Popliteal Fossa: A Case Report and Literature Review
by Gi Beom Kim, Min Cheol Chang and Hyun-Je Kim
Diagnostics 2025, 15(10), 1265; https://doi.org/10.3390/diagnostics15101265 - 16 May 2025
Cited by 1 | Viewed by 674
Abstract
Background/Objectives: Among the various types of masses that can cause compression, hematomas are a relatively common but often overlooked cause. Rheumatoid arthritis (RA) is associated with bleeding problems due to vascular inflammation, platelet dysfunction, impaired production of clotting factors, and medication use. Case [...] Read more.
Background/Objectives: Among the various types of masses that can cause compression, hematomas are a relatively common but often overlooked cause. Rheumatoid arthritis (RA) is associated with bleeding problems due to vascular inflammation, platelet dysfunction, impaired production of clotting factors, and medication use. Case Presentation: We report a case of a 76-year-old woman with RA who developed vascular and neurological symptoms in her right lower leg due to compression of the popliteal artery and tibial nerve by an organized hematoma in the popliteal fossa. She experienced swelling, pain, and plantar flexor weakness in the affected leg with no history of trauma. Magnetic resonance imaging revealed a mass measuring 1.2 × 1.0 × 3.0 cm in size in the right popliteal fossa that was in contact with the popliteal artery and tibial nerve on its posterolateral aspect. Electrodiagnostic examination revealed that the right tibial neuropathy developed most probably around the knee level. Surgical excision of the hematoma resulted in almost complete resolution of symptoms, and excisional biopsy disclosed findings of an organized hematoma. We confirmed that the patient’s symptoms were induced by compression of the popliteal artery and tibial nerve due to the organized hematoma in the right popliteal fossa. Conclusions: This case report emphasizes the importance of considering space-occupying lesions, such as organized hematomas, in patients with RA who develop neurological and vascular symptoms. Full article
(This article belongs to the Special Issue Diagnosis and Management of Musculoskeletal Disorders)
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15 pages, 924 KB  
Article
The Role of Periarticular Knee Muscle Torques in Ensuring the Body Balance of Older Adults with Balance Disturbances
by Piotr Prochor, Łukasz Magnuszewski, Paulina Zalewska, Michał Świętek, Zyta Beata Wojszel and Szczepan Piszczatowski
J. Clin. Med. 2025, 14(9), 3251; https://doi.org/10.3390/jcm14093251 - 7 May 2025
Viewed by 500
Abstract
Background: The role of the periarticular muscles of the knee joint in ensuring body balance is still ambiguous. Therefore, we conducted clinical and biomechanical assessments on 52 older adults (36 women and 16 men, age of 67.58 ± 7.30 years, body weight [...] Read more.
Background: The role of the periarticular muscles of the knee joint in ensuring body balance is still ambiguous. Therefore, we conducted clinical and biomechanical assessments on 52 older adults (36 women and 16 men, age of 67.58 ± 7.30 years, body weight of 75.10 ± 13.42 kg, and height of 163.92 ± 8.80 cm) to determine the role of the knee muscles in balance maintenance. Methods: The clinical examination included the Dizziness Handicap Inventory (DHI), the Geriatric Depression Scale (GDS), the Performance-Oriented Mobility Assessment (POMA), the Functional Reach Test (FRT), the Falls Efficacy Scale—International (FES-I), and bioimpedance parameters (skeletal muscle mass—SMM—and its derived parameter—Diff SMM). The biomechanical assessment involved parameters that characterize muscle torques of knee joint extensors and flexors in isokinetic and isometric conditions, as well as changes in the centre of pressure (COP) position while standing with eyes open and closed. Results: Based on treatment history and DHI results (>10 points), 26 participants were identified as having balance disorders, while the remaining participants formed the control group. Statistical analysis was performed to determine differences between the groups. The groups significantly differed in terms of the results obtained from the DHI (p < 0.001) and GDS (p = 0.04) questionnaires as well as FES-I (p < 0.001) and POMA (p = 0.002) tests. While SMM (p = 0.012) was similar in the groups, Diff SMM (p = 0.04) significantly differed. The multiple regression analysis confirmed the knee joint extensor parameters’ significant role in predicting the COP path (p = 0.03 and p = 0.04 for two assumed models). Conclusions: The obtained results proved that the muscle torques of knee extensors can be used in the diagnostic process of older patients with balance disorders, indicating possible rehabilitation directions. Full article
(This article belongs to the Special Issue Challenges and Advances in Geriatrics and Gerontology)
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