Search Results (11)

Sesame seed oil is a bioactive-rich lipid source, notable for lignans, tocopherols, and unsaturated fatty acids that underpin its antioxidant and cardioprotective properties. This study optimized two innovative, non-thermal extraction techniques—pulsed electric field (PEF) and ultrasound bath-assisted extraction (UBAE)—to maximize yield and preserve oil quality for functional food applications. A blocked definitive screening design combined with response surface methodology modeled the effects of energy power (X₁, 60–100%), liquid-to-solid ratio (X₂, 10–20 mL/g), and extraction time (X₃, 10–30 min) on fat content, DPPH antiradical activity, and oxidative stability indices (Conjugated Dienes, CDs/Conjugated Trienes, CTs). UBAE achieved the highest fat yield—59.0% at low energy (60%), high X₂ (20 mL/g), and short X₃ (10 min)—while PEF maximized DPPH to 36.0 μmol TEAC/kg oil at high energy (100%), moderate X₂ (17 mL/g), and short X₃ (10 min). CDs were minimized to 19.78 mmol/kg (UBAE, 60%, 10 mL/g, 10 min) and CTs to 3.34 mmol/kg (UBAE, 60%, 12 mL/g, 10 min). Partial least squares analysis identified X₂ and X₃ as the most influential variables (VIP > 0.8), with energy–time interplay (X₁ × X₃) being critical for antioxidant capacity. Compared to cold-pressing and Soxhlet extraction, PEF and cold-pressing retained higher antioxidant activity (~19 μmol TEAC/kg) and oxidative stability (TBARS ≤ 0.30 mmol MDAE/kg), while Soxhlet—though yielding 55.65% fat—showed the poorest quality profile (Totox value > 560). Both non-thermal techniques can deliver bioactive-rich sesame oil with lower oxidative degradation, supporting their application in functional foods aimed at improving dietary antioxidant intake and mitigating lipid oxidation burden. PEF at high energy/short time and UBAE at low energy/short time present complementary, scalable options for producing high-value edible oils aligned with human health priorities. As a limitation, we did not directly quantify lignans or tocopherols in this study, and future work will address their measurement and bioaccessibility. Full article

Background and Objectives: Chronic migraines are a disabling neurological disorder with limited response to preventive pharmacological treatments. Greater occipital nerve (GON)-targeted radiofrequency (RF) procedures have emerged as promising interventions, yet long-term comparative data between pulsed RF (PRF) and continuous-lesion RF (LesionRF) remain scarce. This study evaluated the 12-month efficacy and safety of PRF versus LesionRF. Materials and Methods: A single-center cohort of 211 patients with chronic migraine diagnosed by ICHD-3 criteria (PRF = 107; LesionRF = 104) was analyzed. All patients had a positive diagnostic block and ≥12 months of follow-up. Interventions were performed under ultrasound guidance with standardized protocols (PRF: 42 °C, 4 min, 45 V; LesionRF: 80 °C, 90 s). The primary outcome was a change in monthly migraine days (MMD), while secondary outcomes included responder rates (≥50% MMD reduction), pain intensity (VAS), functional outcomes (HIT-6, MIDAS), quality of life (SF-36, EQ-5D), medication use, retreatment, and complications. Results: Both groups improved, but LesionRF showed greater benefit. At 12 months, LesionRF achieved a larger MMD reduction (−4.8 days vs. PRF, p < 0.001), higher responder rates (83% vs. 65%, p = 0.01), and greater VAS decreases (−1.6, p < 0.001). Functional and quality-of-life scores improved more with LesionRF, with MIDAS reductions surpassing MCID and responder rates meeting PASS. Retreatment was less frequent with LesionRF (8% vs. 19%; HR 2.15, p = 0.037), and two LesionRF patients (1.9%) developed hematomas that resolved conservatively. Conclusions: Compared with PRF, LesionRF provided more sustained and clinically meaningful benefits for chronic migraines. Both approaches appeared to be safe, though confirmation in larger randomized trials is warranted. Full article

In order to reduce space occupation and improve reliability, the modularization and integration of micro switches and their components are a necessary path for development. In this paper, a scheme for an alloy metal inertial micro switch using 3D printing technology is proposed for an integrated design. The switch realizes the turn-on function by causing the deformable electrodes to undergo plastic deformation and make close contact with the outer sleeve under the columnar block extrusion. The influence of electrode structure parameters on electrode contact performance was studied by the orthogonal experimental method. And the best parameter combination scheme for the electrode was determined. The aluminum alloy switch and titanium alloy switch were processed by SLM (selective laser melting) technology. The plastic deformation of the 3D-printed titanium alloy electrode occurred later than that of the 3D-printed aluminum alloy electrode under the same impact. The aluminum alloy electrode underwent plastic deformation and realized stable contact with a response time of 5 µs when the impact load was applied with an amplitude of 627 N and a pulse width of 2.7 ms (simulating high acceleration), which meets the application requirement of the response time being no more than 20 µs. The feasibility of 3D printing technology in high-precision and complex-structure micro switch manufacturing was verified. The research in this paper will provide guidance and reference for engineering applications. Full article

It is becoming increasingly common that patients’ preferences move towards non-surgical approaches, such as pulsed magnetic stimulation, for female stress urinary incontinence. Objective: We evaluated the efficacy and safety of a device that uses electromagnetic technology to treat urinary incontinence, with an emphasis on health-related quality of life. Methods: A total of 47 female subjects from 18 to 80 years old were enrolled. After block randomization, treatment consisted of 2 pulsed planar magnetic stimulation sessions per week for 4 weeks (8 sessions). Validated questionnaires: Female Sexual Function Index, International Consultation on Incontinence Questionnaire for Urinary Incontinence: Short Form, and Pelvic Floor Bothersome. Follow-ups were performed at weeks 1, 9, and 14. Results: The present study is one of the first clinical trials published evaluating the efficacy and safety of the electromagnetism-based device with flat configuration in patients with stress urinary incontinence, showing a reduction in PFBQ, ICQSF, and Oxford test scores during follow-up, and significantly at week 14 of follow-up, which implied a favorable impact on clinical outcomes, quality of life, and sexuality. Conclusions: The improved results in the treatment group compared with the simulated group show that pulsed magnetic stimulation is a safe and attractive non-invasive alternative for patients who prefer non-surgical treatments. Full article

The present paper employs a numerical method based on the improved block–pulse basis functions (IBPFs). This was mainly performed to resolve the Volterra–Fredholm integral equations of the second kind. Those equations are often simplified into a linear system of algebraic equations through the use of IBPFs in addition to the operational matrix of integration. Typically, the classical alterations have enhanced the time taken by the computer program to solve the system of algebraic equations. The current modification works perfectly and has improved the efficiency over the regular block–pulse basis functions (BPF). Additionally, the paper handles the uniqueness plus the convergence theorems of the solution. Numerical examples have been presented to illustrate the efficiency as well as the accuracy of the method. Furthermore, tables and graphs are used to show and confirm how the method is highly efficient. Full article

A five-month-old African jenny was presented with a history of exercise intolerance and syncopal episodes. Severe bradycardic arrhythmia due to a high-grade second-degree atrioventricular (AV) block with progression to complete AV block was diagnosed. The jenny underwent a transvenous single-chamber pacemaker implantation. The implantation procedure was performed in a lateral recumbency and the ventricular lead was inserted through the jugular vein. Positioning of the lead was guided by echocardiography. The pacemaker was programmed to VVI mode with a minimal ventricular rate of 40 pulses per minute, a pulse amplitude of 2.4 V, a pulse width of 0.5 ms and sensing amplitude of 2.5 mV. Short-term complications associated with the procedure included lead dislodgement and pacemaker pocket infection. The long-term outcome was satisfactory; the jenny showed improvement in heart function and quality of life after pacemaker implantation. The pulse generator replacement was performed twice (at nine-year intervals) and the intervention was always associated with a local inflammatory reaction around the pacing device. Cardiac examination 18 years after pacemaker implantation revealed no morphological changes in the heart; the electrode lead was still in the correct position and successful pacing and sensing of the ventricle were obtained. Regular follow-up checks are important to evaluate pacemaker function. Full article

Ice accumulation on wind turbine blades due to the impact of supercooled water droplets can be reduced by the application of surfaces with anti-icing properties. Hydrophobic surfaces are considered as a promising solution because of their water repellent behavior. In recent years, short-pulsed laser technologies have been developed as an efficient technique to modify the surface properties of materials. However, the anti-icing properties of such surfaces have not yet been validated. In this work, a hybrid modification of polyester resin-based gelcoats was adopted. Laser patterning (LP) was used to produce periodic surface structures on modified unsaturated polyester resin (UPR) substrates. One of the innovations of this research is the utilization of novel purpose-made chemical modifiers for gelcoats. The implementation of linear polymethylhydrosiloxane (PMHS) as a building block is a key improvement in terms of durability and functionality of the coating, since there is an option of introducing not only groups bonding in the polyester into one molecule, but also groups that increase hydrophobicity. The other novelty is a successfully conducted experiment combining such chemical modification with laser texturization of the surface. The influence of the laser energy, pattern shape, and spatial periods on the topographical characteristics and hydrophobicity as well as the anti-icing properties of the produced surfaces were investigated. To characterize the surface topography of the produced structures, scanning electron microscopy (SEM) and profilometer were utilized. Measurements of the wettability parameters (static contact angle and contact angle hysteresis) on the treated surfaces allowed the identification of the influence of wetting behavior and laser parameters on the investigated materials. Anti-icing properties were characterized by ice adhesion (IA) and freezing delay time (FDT) tests. It was found that hybrid modification of unsaturated polyester resin by chemical modifiers and laser treatment increased the hydrophobic and anti-icing properties of polyester gelcoats. Full article

The operation mode of a single strip provides incomplete side-scan sonar image in a specific environment and range, resulting in the overlapping area between adjacent strips often with imperfect detection information or inaccurate target contour. In this paper, a sum-modified Laplacian energy filtering (SMLF) and improved dual-channel pulse coupled neural network (IDPCNN) are proposed for image fusion of side-scan sonar in the domain of nonsubsampled contourlet transform (NSCT). Among them, SMLF energy is applied to extract the fusion coefficients of the low frequency sub-band, which combines the characteristics of energy information, human visual contrast, and guided filtering to eliminate the pseudo contour effect of block flow. In addition, the IDPCNN model, which utilizes the average gradient, soft limit function, and novel sum-modified Laplacian (NSML) to adaptively represent the corresponding excitation parameters, is applied to improve the depth and activity of pulse ignition, so as to quickly and accurately select the image coefficients of the high frequency sub-band. The experimental results show that the proposed method displays fine geomorphic information and clear target contour in the overlapping area of adjacent strips. The objective index values are generally optimal, which reflect the information of image edge, clarity, and overall similarity. Full article

Structural quality of LuFeO ${}_3$ epitaxial layers grown by pulsed-laser deposition on sapphire substrates with and without platinum Pt interlayers has been investigated by in situ high-resolution X-ray diffraction (reciprocal-space mapping). The parameters of the structure such as size and misorientation of mosaic blocks have been determined as functions of the thickness of LuFeO ${}_3$ during growth and for different thicknesses of platinum interlayers up to 40 nm. By means of fitting of the time-resolved X-ray reflectivity curves and by in situ X-ray diffraction measurement, we demonstrate that the LuFeO ${}_3$ growth rate as well as the out-of-plane lattice parameter are almost independent from Pt interlayer thickness, while the in-plane LuFeO ${}_3$ lattice parameter decreases. We reveal that, despite the different morphologies of the Pt interlayers with different thickness, LuFeO ${}_3$ was growing as a continuous mosaic layer and the misorientation of the mosaic blocks decreases with increasing Pt thickness. The X-ray diffraction results combined with ex situ scanning electron microscopy and high-resolution transmission electron microscopy demonstrate that the Pt interlayer significantly improves the structure of LuFeO ${}_3$ by reducing the misfit of the LuFeO ${}_3$ lattice with respect to the material underneath. Full article

In this paper, we present results concerning the design, the realization and the characterization of a photovoltaic system (PV), equipped with a digital controls: Power Point Tracking (MPPT), charge/discharge lead acid batteries, sun tracker and supervision. These different functions are performed with a microcontroller that has capabilities and functions to the reliability of PV systems (signal generation Pulses Width Modulation (PWM), speed etc.). Concerning the MPPT control operation, we improved the accuracy and reliability of research by improving the search algorithm “Hill Climbing” taking into account the optimal operation of PV panels depending on weather conditions (temperature and light).The experiment of each block shows that the MPPT control converges instantly the operating point of the PV panels around the maximum power point, independently of sudden changes of the illumination or the load. The control blocks charge/discharge battery and sun tracking show good control of charge/discharge lead acid batteries and the need of sun tracker to increase the power supplied by the PV panel. By using the improved MPPT control, loss of power supplied by the PV panels are very low (below 5%). Full article

The presence of mesopores in the interior of microporous particles may significantly improve their transport properties. Complementing previous macroscopic transient sorption experiments and pulsed field gradient NMR self-diffusion studies with such materials, the present study is dedicated to an in-depth study of molecular uptake and release on the individual particles of mesoporous zeolitic specimens, notably with samples of the narrow-pore structure types, CHA and LTA. The investigations are focused on determining the time constants and functional dependences of uptake and release. They include a systematic variation of the architecture of the mesopores and of the guest molecules under study as well as a comparison of transient uptake with blocked and un-blocked mesopores. In addition to accelerating intracrystalline mass transfer, transport enhancement by mesopores is found to be, possibly, also caused by a reduction of transport resistances on the particle surfaces. Full article