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29 pages, 12751 KB  
Review
A Research Landscape of Agentic AI and Large Language Models: Applications, Challenges and Future Directions
by Sarfraz Brohi, Qurat-ul-ain Mastoi, N. Z. Jhanjhi and Thulasyammal Ramiah Pillai
Algorithms 2025, 18(8), 499; https://doi.org/10.3390/a18080499 - 11 Aug 2025
Viewed by 1181
Abstract
Agentic AI and Large Language Models (LLMs) are transforming how language is understood and generated while reshaping decision-making, automation, and research practices. LLMs provide underlying reasoning capabilities, and Agentic AI systems use them to perform tasks through interactions with external tools, services, and [...] Read more.
Agentic AI and Large Language Models (LLMs) are transforming how language is understood and generated while reshaping decision-making, automation, and research practices. LLMs provide underlying reasoning capabilities, and Agentic AI systems use them to perform tasks through interactions with external tools, services, and Application Programming Interfaces (APIs). Based on a structured scoping review and thematic analysis, this study identifies that core challenges of LLMs, relating to security, privacy and trust, misinformation, misuse and bias, energy consumption, transparency and explainability, and value alignment, can propagate into Agentic AI. Beyond these inherited concerns, Agentic AI introduces new challenges, including context management, security, privacy and trust, goal misalignment, opaque decision-making, limited human oversight, multi-agent coordination, ethical and legal accountability, and long-term safety. We analyse the applications of Agentic AI powered by LLMs across six domains: education, healthcare, cybersecurity, autonomous vehicles, e-commerce, and customer service, to reveal their real-world impact. Furthermore, we demonstrate some LLM limitations using DeepSeek-R1 and GPT-4o. To the best of our knowledge, this is the first comprehensive study to integrate the challenges and applications of LLMs and Agentic AI within a single forward-looking research landscape that promotes interdisciplinary research and responsible advancement of this emerging field. Full article
(This article belongs to the Special Issue Evolution of Algorithms in the Era of Generative AI)
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19 pages, 26396 KB  
Article
Development of a Networked Multi-Participant Driving Simulator with Synchronized EEG and Telemetry for Traffic Research
by Poorendra Ramlall, Ethan Jones and Subhradeep Roy
Systems 2025, 13(7), 564; https://doi.org/10.3390/systems13070564 - 10 Jul 2025
Viewed by 557
Abstract
This paper presents a multi-participant driving simulation framework designed to support traffic experiments involving the simultaneous collection of vehicle telemetry and cognitive data. The system integrates motion-enabled driving cockpits, high-fidelity steering and pedal systems, immersive visual displays (monitor or virtual reality), and the [...] Read more.
This paper presents a multi-participant driving simulation framework designed to support traffic experiments involving the simultaneous collection of vehicle telemetry and cognitive data. The system integrates motion-enabled driving cockpits, high-fidelity steering and pedal systems, immersive visual displays (monitor or virtual reality), and the Assetto Corsa simulation engine. To capture cognitive states, dry-electrode EEG headsets are used alongside a custom-built software tool that synchronizes EEG signals with vehicle telemetry across multiple drivers. The primary contribution of this work is the development of a modular, scalable, and customizable experimental platform with robust data synchronization, enabling the coordinated collection of neural and telemetry data in multi-driver scenarios. The synchronization software developed through this study is freely available to the research community. This architecture supports the study of human–human interactions by linking driver actions with corresponding neural activity across a range of driving contexts. It provides researchers with a powerful tool to investigate perception, decision-making, and coordination in dynamic, multi-participant traffic environments. Full article
(This article belongs to the Special Issue Modelling and Simulation of Transportation Systems)
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39 pages, 1775 KB  
Article
A Survey on UAV Control with Multi-Agent Reinforcement Learning
by Chijioke C. Ekechi, Tarek Elfouly, Ali Alouani and Tamer Khattab
Drones 2025, 9(7), 484; https://doi.org/10.3390/drones9070484 - 9 Jul 2025
Viewed by 3095
Abstract
Unmanned Aerial Vehicles (UAVs) have become increasingly prevalent in both governmental and civilian applications, offering significant reductions in operational costs by minimizing human involvement. There is a growing demand for autonomous, scalable, and intelligent coordination strategies in complex aerial missions involving multiple Unmanned [...] Read more.
Unmanned Aerial Vehicles (UAVs) have become increasingly prevalent in both governmental and civilian applications, offering significant reductions in operational costs by minimizing human involvement. There is a growing demand for autonomous, scalable, and intelligent coordination strategies in complex aerial missions involving multiple Unmanned Aerial Vehicles (UAVs). Traditional control techniques often fall short in dynamic, uncertain, or large-scale environments where decentralized decision-making and inter-agent cooperation are crucial. A potentially effective technique used for UAV fleet operation is Multi-Agent Reinforcement Learning (MARL). MARL offers a powerful framework for addressing these challenges by enabling UAVs to learn optimal behaviors through interaction with the environment and each other. Despite significant progress, the field remains fragmented, with a wide variety of algorithms, architectures, and evaluation metrics spread across domains. This survey aims to systematically review and categorize state-of-the-art MARL approaches applied to UAV control, identify prevailing trends and research gaps, and provide a structured foundation for future advancements in cooperative aerial robotics. The advantages and limitations of these techniques are discussed along with suggestions for further research to improve the effectiveness of MARL application to UAV fleet management. Full article
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12 pages, 17214 KB  
Technical Note
A Prototype Crop Management Platform for Low-Tunnel-Covered Strawberries Using Overhead Power Cables
by Omeed Mirbod and Marvin Pritts
AgriEngineering 2025, 7(7), 210; https://doi.org/10.3390/agriengineering7070210 - 2 Jul 2025
Viewed by 443
Abstract
The continuous and reliable operation of autonomous systems is important for farm management decision making, whether such systems perform crop monitoring using imaging systems or crop handling in pruning and harvesting applications using robotic manipulators. Autonomous systems, including robotic ground vehicles, drones, and [...] Read more.
The continuous and reliable operation of autonomous systems is important for farm management decision making, whether such systems perform crop monitoring using imaging systems or crop handling in pruning and harvesting applications using robotic manipulators. Autonomous systems, including robotic ground vehicles, drones, and tractors, are major research efforts of precision crop management. However, these systems may be less effective or require specific customizations for planting systems in low tunnels, high tunnels, or other environmentally controlled enclosures. In this work, a compact and lightweight crop management platform is developed that uses overhead power cables for continuous operation over row crops, requiring less human intervention and independent of the ground terrain conditions. The platform does not carry batteries onboard for its operation, but rather pulls power from overhead cables, which it also uses to navigate over crop rows. It is developed to be modular, with the top section consisting of mobility and power delivery and the bottom section addressing a custom task, such as incorporating additional sensors for crop monitoring or manipulators for crop handling. This prototype illustrates the infrastructure, locomotive mechanism, and sample usage of the system (crop imaging) in the application of low-tunnel-covered strawberries; however, there is potential for other row crop systems with regularly spaced support structures to adopt this platform as well. Full article
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19 pages, 2374 KB  
Article
Analysis of Opportunities to Reduce CO2 and NOX Emissions Through the Improvement of Internal Inter-Operational Transport
by Szymon Pawlak, Tomasz Małysa, Angieszka Fornalczyk, Angieszka Sobianowska-Turek and Marzena Kuczyńska-Chałada
Sustainability 2025, 17(13), 5974; https://doi.org/10.3390/su17135974 - 29 Jun 2025
Viewed by 477
Abstract
The reduction of environmental pollutant emissions—including greenhouse gases, particulate matter, and other harmful substances—represents one of the foremost challenges in climate policy, economics, and industrial management today. Excessive emissions of CO2, NOX, and suspended particulates exert significant impacts on [...] Read more.
The reduction of environmental pollutant emissions—including greenhouse gases, particulate matter, and other harmful substances—represents one of the foremost challenges in climate policy, economics, and industrial management today. Excessive emissions of CO2, NOX, and suspended particulates exert significant impacts on climate change as well as human health and welfare. Consequently, numerous studies and regulatory and technological initiatives are underway to mitigate these emissions. One critical area is intra-plant transport within manufacturing facilities, which, despite its localized scope, can substantially contribute to a company’s total emissions. This paper aims to assess the potential of computer simulation using FlexSim software as a decision-support tool for planning inter-operational transport, with a particular focus on environmental aspects. The study analyzes real operational data from a selected production plant (case study), concentrating on the optimization of the number of transport units, their routing, and the layout of workstations. It is hypothesized that reducing the number of trips, shortening transport routes, and efficiently utilizing transport resources can lead to lower emissions of carbon dioxide (CO2) and nitrogen oxides (NOX). The findings provide a basis for a broader adoption of digital tools in sustainable production planning, emphasizing the integration of environmental criteria into decision-making processes. Furthermore, the results offer a foundation for future analyses that consider the development of green transport technologies—such as electric and hydrogen-powered vehicles—in the context of their implementation in the internal logistics of manufacturing enterprises. Full article
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17 pages, 5666 KB  
Article
Mechatronic and Robotic Systems Utilizing Pneumatic Artificial Muscles as Actuators
by Željko Šitum, Juraj Benić and Mihael Cipek
Inventions 2025, 10(4), 44; https://doi.org/10.3390/inventions10040044 - 23 Jun 2025
Viewed by 509
Abstract
This article presents a series of innovative systems developed through student laboratory projects, comprising two autonomous vehicles, a quadrupedal walking robot, an active ankle-foot orthosis, a ball-on-beam balancing mechanism, a ball-on-plate system, and a manipulator arm, all actuated by pneumatic artificial muscles (PAMs). [...] Read more.
This article presents a series of innovative systems developed through student laboratory projects, comprising two autonomous vehicles, a quadrupedal walking robot, an active ankle-foot orthosis, a ball-on-beam balancing mechanism, a ball-on-plate system, and a manipulator arm, all actuated by pneumatic artificial muscles (PAMs). Due to their flexibility, low weight, and compliance, fluidic muscles demonstrate substantial potential for integration into various mechatronic systems, robotic platforms, and manipulators. Their capacity to generate smooth and adaptive motion is particularly advantageous in applications requiring natural and human-like movements, such as rehabilitation technologies and assistive devices. Despite the inherent challenges associated with nonlinear behavior in PAM-actuated control systems, their biologically inspired design remains promising for a wide range of future applications. Potential domains include industrial automation, the automotive and aerospace sectors, as well as sports equipment, medical assistive devices, entertainment systems, and animatronics. The integration of self-constructed laboratory systems powered by PAMs into control systems education provides a comprehensive pedagogical framework that merges theoretical instruction with practical implementation. This methodology enhances the skillset of future engineers by deepening their understanding of core technical principles and equipping them to address emerging challenges in engineering practice. Full article
(This article belongs to the Section Inventions and Innovation in Advanced Manufacturing)
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22 pages, 1664 KB  
Article
Techno-Economic Assessment of Alternative-Fuel Bus Technologies Under Real Driving Conditions in a Developing Country Context
by Marc Haddad and Charbel Mansour
World Electr. Veh. J. 2025, 16(6), 337; https://doi.org/10.3390/wevj16060337 - 19 Jun 2025
Cited by 1 | Viewed by 825
Abstract
The long-standing need for a modern public transportation system in Lebanon, a developing country of the Middle East with an almost exclusive dependence on costly and polluting passenger cars, has become more pressing in recent years due to the worsening economic crisis and [...] Read more.
The long-standing need for a modern public transportation system in Lebanon, a developing country of the Middle East with an almost exclusive dependence on costly and polluting passenger cars, has become more pressing in recent years due to the worsening economic crisis and the onset of hyperinflation. This study investigates the potential reductions in energy use, emissions, and costs from the possible introduction of natural gas, hybrid, and battery-electric buses compared to traditional diesel buses in local real driving conditions. Four operating conditions were considered including severe congestion, peak, off-peak, and bus rapid transit (BRT) operation. Battery-electric buses are found to be the best performers in any traffic operation, conditional on having clean energy supply at the power plant and significant subsidy of bus purchase cost. Natural gas buses do not provide significant greenhouse gas emission savings compared to diesel buses but offer substantial reductions in the emission of all major pollutants harmful to human health. Results also show that accounting for additional energy consumption from the use of climate-control auxiliaries in hot and cold weather can significantly impact the performance of all bus technologies by up to 44.7% for electric buses on average. Performance of all considered bus technologies improves considerably in free-flowing traffic conditions, making BRT operation the most beneficial. A vehicle mix of diesel, natural gas, and hybrid bus technologies is found most feasible for the case of Lebanon and similar developing countries lacking necessary infrastructure for a near-term transition to battery-electric technology. Full article
(This article belongs to the Special Issue Zero Emission Buses for Public Transport)
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14 pages, 9364 KB  
Article
Development of Autonomous Electric USV for Water Quality Detection
by Chiung-Hsing Chen, Yi-Jie Shang, Yi-Chen Wu and Yu-Chen Lin
Sensors 2025, 25(12), 3747; https://doi.org/10.3390/s25123747 - 15 Jun 2025
Viewed by 942
Abstract
With the rise of industry, river pollution has become increasingly severe. Countries worldwide now face the challenge of effectively and promptly detecting river pollution. Traditional river detection methods rely on manual sampling and subsequent data analysis at various sampling sites, requiring significant time [...] Read more.
With the rise of industry, river pollution has become increasingly severe. Countries worldwide now face the challenge of effectively and promptly detecting river pollution. Traditional river detection methods rely on manual sampling and subsequent data analysis at various sampling sites, requiring significant time and labor costs. This article proposes using an electric unmanned surface vehicle (USV) to replace manual river and lake water quality detection, utilizing a 2.4 G high-power wireless data transmission system, an M9N GPS antenna, and an automatic identification system (AIS) to achieve remote and unmanned control. The USV is capable of autonomously navigating along pre-defined routes and conducting water quality measurements without human intervention. The water quality detection system includes sensors for pH, dissolved oxygen (DO), electrical conductivity (EC), and oxidation-reduction potential (ORP). This design uses a modular structure, it is easy to maintain, and it supports long-range wireless communication. These features help to reduce operational and maintenance costs in the long term. The data produced using this method effectively reflect the current state of river water quality and indicate whether pollution is present. Through practical testing, this article demonstrates that the USV can perform precise positioning while utilizing AIS to identify potential surrounding collision risks for the remote planning of water quality detection sailing routes. This autonomous approach enhances the efficiency of water sampling in rivers and lakes and significantly reduces labor requirements. At the same time, this contributes to the achievement of the United Nations Sustainable Development Goals (SDG 14), “Life Below Water”. Full article
(This article belongs to the Special Issue Sensors for Water Quality Monitoring and Assessment)
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44 pages, 5969 KB  
Article
iRisk: Towards Responsible AI-Powered Automated Driving by Assessing Crash Risk and Prevention
by Naomi Y. Mbelekani and Klaus Bengler
Electronics 2025, 14(12), 2433; https://doi.org/10.3390/electronics14122433 - 14 Jun 2025
Viewed by 806
Abstract
Advanced technology systems and neuroelectronics for crash risk assessment and anticipation may be a promising field for advancing responsible automated driving on urban roads. In principle, there are prospects of an artificially intelligent (AI)-powered automated vehicle (AV) system that tracks the degree of [...] Read more.
Advanced technology systems and neuroelectronics for crash risk assessment and anticipation may be a promising field for advancing responsible automated driving on urban roads. In principle, there are prospects of an artificially intelligent (AI)-powered automated vehicle (AV) system that tracks the degree of perceived crash risk (as either low, mid, or high) and perceived safety. As a result, communicating (verbally or nonverbally) this information to the user based on human factor aspects should be reflected. As humans and vehicle automation systems are prone to error, we need to design advanced information and communication technologies that monitor risks and act as a mediator when necessary. One possible approach is towards designing a crash risk classification and management system. This would be through responsible AI that monitors the user’s mental states associated with risk-taking behaviour and communicates this information to the user, in conjunction with the driving environment and AV states. This concept is based on a literature review and industry experts’ perspectives on designing advanced technology systems that support users in preventing crash risk encounters due to long-term effects. Equally, learning strategies for responsible automated driving on urban roads were designed. In a sense, this paper offers the reader a meticulous discussion on conceptualising a safety-inspired ‘ergonomically responsible AI’ concept in the form of an intelligent risk assessment system (iRisk) and an AI-powered Risk information Human–Machine Interface (AI rHMI) as a useful concept for responsible automated driving and safe human–automation interaction. Full article
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20 pages, 14992 KB  
Article
A Lightweight Bioinspired SMA-Based Grasping Mechanism for Flapping Wing MAVs
by Ahmad Hammad, Mehmet Süer and Sophie F. Armanini
Biomimetics 2025, 10(6), 364; https://doi.org/10.3390/biomimetics10060364 - 4 Jun 2025
Viewed by 710
Abstract
This study presents a novel, bioinspired perching mechanism designed to enhance the landing and takeoff capabilities of flapping wing micro aerial vehicles (FWMAVs). Drawing inspiration from the human hand, the lightweight gripper integrates a compliant claw structure actuated by shape memory alloys (SMAs) [...] Read more.
This study presents a novel, bioinspired perching mechanism designed to enhance the landing and takeoff capabilities of flapping wing micro aerial vehicles (FWMAVs). Drawing inspiration from the human hand, the lightweight gripper integrates a compliant claw structure actuated by shape memory alloys (SMAs) that mimic muscle movement. These SMA springs act as compact, lightweight substitutes for traditional actuators like motors or solenoids. The mechanism operates via short electrical impulses that trigger both opening and closing motions. A detailed design process was undertaken to optimize phalange lengths for cylindrical grasping and to select appropriate SMAs for reliable performance. Weighing only 50 g, the gripper leverages the high power-to-weight ratio and flexibility of SMAs, with the springs directly embedded within the phalanges to reduce size and mass while preserving high-force output. Experimental results demonstrate fast actuation and a grasping force of approximately 16 N, enabling the gripper to hold objects of varying shapes and sizes and perform perching, grasping, and carrying tasks. Compared to existing solutions, this mechanism offers a simpler, highly integrated structure with enhanced miniaturization and adaptability, making it especially suitable for low-payload MAV platforms like FWMAVs. Full article
(This article belongs to the Special Issue Bio-Inspired Robotics and Applications 2025)
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25 pages, 1595 KB  
Review
Research Status and Development Trends of Deep Reinforcement Learning in the Intelligent Transformation of Agricultural Machinery
by Jiamuyang Zhao, Shuxiang Fan, Baohua Zhang, Aichen Wang, Liyuan Zhang and Qingzhen Zhu
Agriculture 2025, 15(11), 1223; https://doi.org/10.3390/agriculture15111223 - 4 Jun 2025
Cited by 2 | Viewed by 1459
Abstract
With the acceleration of agricultural intelligent transformation, deep reinforcement learning (DRL), leveraging its adaptive perception and decision-making capabilities in complex environments, has emerged as a pivotal technology in advancing the intelligent upgrade of agricultural machinery and equipment. For example, in UAV path optimization, [...] Read more.
With the acceleration of agricultural intelligent transformation, deep reinforcement learning (DRL), leveraging its adaptive perception and decision-making capabilities in complex environments, has emerged as a pivotal technology in advancing the intelligent upgrade of agricultural machinery and equipment. For example, in UAV path optimization, DRL can help UAVs plan more efficient flight paths to cover more areas in less time. To enhance the systematicity and credibility of this review, this paper systematically examines the application status, key issues, and development trends of DRL in agricultural scenarios, based on the research literature from mainstream Chinese and English databases spanning from 2018 to 2024. From the perspective of algorithm–hardware synergy, the article provides an in-depth analysis of DRL’s specific applications in agricultural ground platform navigation, path planning for intelligent agricultural end-effectors, and autonomous operations of low-altitude unmanned aerial vehicles. It highlights the technical advantages of DRL by integrating typical experimental outcomes, such as improved path-tracking accuracy and optimized spraying coverage. Meanwhile, this paper identifies three major challenges facing DRL in agricultural contexts: the difficulty of dynamic path planning in unstructured environments, constraints imposed by edge computing resources on algorithmic real-time performance, and risks to policy reliability and safety under human–machine collaboration conditions. Looking forward, the DRL-driven smart transformation of agricultural machinery will focus on three key aspects: (1) The first aspect is developing a hybrid decision-making architecture based on model predictive control (MPC). This aims to enhance the strategic stability and decision-making interpretability of agricultural machinery (like unmanned tractors, harvesters, and drones) in complex and dynamic field environments. This is essential for ensuring the safe and reliable autonomous operation of machinery. (2) The second aspect is designing lightweight models that support edge-cloud collaborative deployment. This can meet the requirements of low-latency responses and low-power operation in edge computing scenarios during field operations, providing computational power for the real-time intelligent decision-making of machinery. (3) The third aspect is integrating meta-learning with self-supervised mechanisms. This helps improve the algorithm’s fast generalization ability across different crop types, climates, and geographical regions, ensuring the smart agricultural machinery system has broad adaptability and robustness and accelerating its application in various agricultural settings. This paper proposes research directions from three key dimensions-“algorithm capability enhancement, deployment architecture optimization, and generalization ability improvement”-offering theoretical references and practical pathways for the continuous evolution of intelligent agricultural equipment. Full article
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25 pages, 10685 KB  
Article
Exploitation and Maintenance of Biomethane-Powered Truck and Bus Fleets to Assure Safety and Mitigation of Greenhouse Gas Emissions
by Saša Milojević, Ondrej Stopka, Olga Orynycz, Karol Tucki, Branislav Šarkan and Slobodan Savić
Energies 2025, 18(9), 2218; https://doi.org/10.3390/en18092218 - 27 Apr 2025
Cited by 1 | Viewed by 722
Abstract
Motor vehicles in transport, as one of the important sectors of the economy, emit a significant amount of carbon dioxide and other products in the form of exhaust gases, which are harmful to human health. The emission of exhaust gases from motor vehicles [...] Read more.
Motor vehicles in transport, as one of the important sectors of the economy, emit a significant amount of carbon dioxide and other products in the form of exhaust gases, which are harmful to human health. The emission of exhaust gases from motor vehicles is limited by appropriate regulations in accordance with environmental goals, such as the Paris Climate Agreement. Reduced emissions and fuel (energy) consumption is mainly achieved by applying modern technologies for the production of internal combustion engines; transitioning to cleaner fuels, such as renewable natural gas or biomethane; and using alternative propulsion systems. Biomethane stored in a liquid state in on-board reservoirs has advantages in truck transport, ships, and air traffic. The reason for this is due to the higher concentration of energy per unit volume of the reservoirs and the lower storage pressure and thus higher safety compared to the high-pressure storage option (compressed biomethane). The presented research is related to a proposition regarding the design of drive systems of city buses using biomethane as fuel in cases when fuel is stored on-board the vehicle as gas in a compressed aggregate state. In this study, the results of a calculation method regarding the roof-supporting structure of an experimental bus with gas reservoirs under higher pressure are discussed as well. This study also presents the possibility of reducing harmful emissions if biomethane is used instead of conventional fuels as a transitional solution to electric-powered vehicles. For the sake of comparison, it is suggested that the engaged energy and the amount of produced carbon dioxide emissions within the drive systems of different fuels are calculated according to the recommendations of the standard EN16258:2012. Full article
(This article belongs to the Section C: Energy Economics and Policy)
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18 pages, 4761 KB  
Article
Fluorescence Resonance Energy Transfer for Drug Loading Assessment in Reconstituted High-Density Lipoprotein Nanoparticles
by R. Max Petty, Luca Ceresa, Emma Alexander, Danh Pham, Nirupama Sabnis, Rafal Fudala, Andras G. Lacko, Raghu R. Krishnamoorthy, Zygmunt Gryczynski and Ignacy Gryczynski
Int. J. Mol. Sci. 2025, 26(7), 3276; https://doi.org/10.3390/ijms26073276 - 1 Apr 2025
Viewed by 749
Abstract
Reconstituted high-density lipoprotein nanoparticles (NPs), which mimic the structure and function of endogenous human plasma HDL, hold promise as a robust drug delivery system. These nanoparticles, when loaded with appropriate agents, serve as powerful tools for targeted drug delivery. The fundamental challenge lies [...] Read more.
Reconstituted high-density lipoprotein nanoparticles (NPs), which mimic the structure and function of endogenous human plasma HDL, hold promise as a robust drug delivery system. These nanoparticles, when loaded with appropriate agents, serve as powerful tools for targeted drug delivery. The fundamental challenge lies in controlling and estimating the actual drug load and the efficiency of drug release at the target. In this report, we present a novel approach based on enhanced Förster Resonance Energy Transfer (FRET) to assess particle load and monitor payload release. The NPs are labeled with donor molecules embedded in the lipid phase, while the spherical core volume is filled with acceptor molecules. Highly enhanced FRET efficiency to multiple acceptors in the NP core has been observed at distances significantly larger than the characteristic Förster distance (R0). To confirm that the observed changes in donor and acceptor emissions are a result of FRET, we developed a theoretical model for nonradiative energy transfer from a single donor to multiple acceptors enclosed in a spherical core volume. The load-dependent shortening of the fluorescence lifetime of the donor correlated with the presence of a negative component in the intensity decay of the acceptor clearly demonstrates that FRET can occur at a large distance comparable to the nanoparticle size (over 100 Å). Comparison of theoretical simulations with the measured intensity decays of the donor and acceptor fluorophores constitute a new method for evaluating particle load. The observed FRET efficiency depends on the number of acceptors in the core, providing a simple way to estimate the nanoparticle load efficiency. Particle disintegration and load release result in a distinct change in donor and acceptor emissions. This approach constitutes a novel strategy for assessing NP core load, monitoring NP integrity, and evaluating payload release efficiency to target cells. Significants: In the last decade, nanoparticles have emerged as a promising strategy for targeted drug delivery, with applications ranging from cancer therapy to ocular neurodegenerative disease treatments. Despite their potential, a significant issue has been the real-time monitoring of these drug delivery vehicles within biological systems. Effective strategies for monitoring NP payload loading, NP integrity, and payload release are needed to assess the quality of new drug delivery systems. In our study, we have found that FRET-enabled NPs function as an improved method for monitoring these aspects currently missing from current drug delivery efforts. Full article
(This article belongs to the Section Molecular Pharmacology)
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15 pages, 6244 KB  
Article
Detailed Investigation of Cobalt-Rich Crusts in Complex Seamount Terrains Using the Haima ROV: Integrating Optical Imaging, Sampling, and Acoustic Methods
by Yonghang Li, Huiqiang Yao, Zongheng Chen, Lixing Wang, Haoyi Zhou, Shi Zhang and Bin Zhao
J. Mar. Sci. Eng. 2025, 13(4), 702; https://doi.org/10.3390/jmse13040702 - 1 Apr 2025
Viewed by 745
Abstract
The remotely operated vehicle (ROV), a vital deep-sea platform, offers key advantages, including operational duration via continuous umbilical power, high task adaptability, and zero human risk. It has become indispensable for deep-sea scientific research and marine engineering. To enhance surveys of cobalt-rich crusts [...] Read more.
The remotely operated vehicle (ROV), a vital deep-sea platform, offers key advantages, including operational duration via continuous umbilical power, high task adaptability, and zero human risk. It has become indispensable for deep-sea scientific research and marine engineering. To enhance surveys of cobalt-rich crusts (CRCs) on complex seamount terrains, the 4500-m-class Haima ROV integrates advanced payloads, such as underwater positioning systems, multi-angle cameras, multi-functional manipulators, subsea shallow drilling systems, sediment samplers, and acoustic crust thickness gauges. Coordinated control between deck monitoring and subsea units enables stable multi-task execution within single dives, significantly improving operational efficiency. Survey results from Caiwei Guyot reveal the following: (1) ROV-collected data were highly reliable, with high-definition video mapping CRCs distribution across varied terrains. Captured crust-bearing rocks weighed up to 78 kg, drilled cores reached 110 cm, and acoustic thickness measurements had a 1–2 cm margin of error compared to in situ cores; (2) Video and cores analysis showed summit platforms (3–5° slopes) dominated by tabular crusts with gravel-type counterparts, summit margins (5–10° slopes) hosting gravel crusts partially covered by sediment, and steep slopes (12–15° slopes) exhibiting mixed crust types under sediment coverage. Thicker crusts clustered at summit margins (14 and 15 cm, respectively) compared to thinner crusts on platforms and slopes (10 and 7 cm, respectively). The Haima ROV successfully investigated CRC resources in complex terrains, laying the groundwork for seamount crust resource evaluations. Future advancements will focus on high-precision navigation and control, high-resolution crust thickness measurement, optical imaging optimization, and AI-enhanced image recognition. Full article
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18 pages, 9580 KB  
Article
Development and Implementation of an Autonomous Control System for a Micro-Turbogenerator Installed on an Unmanned Aerial Vehicle
by Tiberius-Florian Frigioescu, Daniel-Eugeniu Crunțeanu, Maria Căldărar, Mădălin Dombrovschi, Gabriel-Petre Badea and Alexandra Nistor
Electronics 2025, 14(6), 1212; https://doi.org/10.3390/electronics14061212 - 19 Mar 2025
Cited by 1 | Viewed by 500
Abstract
The field of unmanned aerial vehicles (UAVs) has experienced substantial growth, with applications expanding across diverse domains. Missions increasingly demand higher autonomy, reducing human intervention and relying more on advanced onboard systems. However, integrating hybrid power sources, especially micro-turboprop engines, into UAVs poses [...] Read more.
The field of unmanned aerial vehicles (UAVs) has experienced substantial growth, with applications expanding across diverse domains. Missions increasingly demand higher autonomy, reducing human intervention and relying more on advanced onboard systems. However, integrating hybrid power sources, especially micro-turboprop engines, into UAVs poses significant challenges due to their complexity, hindering the development of effective power management control systems. This research aims to design a control algorithm for dynamic power allocation based on UAV operational needs. A fuzzy logic-based control algorithm was implemented on the Single-Board Computer (SBC) of a micro-turbogenerator test bench, which was previously developed in an earlier study. After implementing and testing the algorithm, voltage stabilization was achieved at improved levels by tightening the membership function constraints of the fuzzy logic controller. Automating the throttle control of the Electric Ducted Fan (EDF), the test platform’s primary power consumer, enabled the electric generator’s maximum capacity to be reached. This result indicates the necessity of replacing the current electric motor with one that is capable of higher power outputs to support the system’s enhanced performance. Full article
(This article belongs to the Section Systems & Control Engineering)
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