Search Results (11,703)

The increasing prevalence of multiclass pesticide residues in aquatic environments poses a significant threat to ecosystems and human health. To address this challenge, magnetic Fe₃O₄@Co₅Al-LDH nanoparticles were synthesized as high-performance, easily recoverable catalysts for the peroxymonosulfate (PMS)-mediated degradation of epoxiconazole, atrazine, and metalaxyl. Under optimized conditions (pH 7.0, 35 mg catalyst, and 4.0 mM PMS), the system achieved 100% degradation of the three coexisting pesticides within 15 min. Quenching experiments and electron paramagnetic resonance (EPR) spectroscopy confirmed that SO₄⁻ and ^•OH radicals were the primary reactive species driving the process. Liquid chromatography–mass spectrometry (LC-MS) analysis identified four intermediates for epoxiconazole, three for atrazine, and four for metalaxyl, facilitating the proposal of distinct degradation pathways. The degradation mechanism revealed that electron transfer between Fe/Co and PMS promoted the generation of reactive oxygen species, leading to dechlorination, hydroxylation, and dealkylation of the pesticides transiently adsorbed on the surface of Fe₃O₄@Co₅Al-LDH. In summary, this study demonstrates that Fe₃O₄@Co₅Al-LDH is an easily recoverable, reusable, and cost-effective catalyst for the simultaneous remediation of complex pesticide mixtures in water. Full article

Cadmium (Cd) contamination in agricultural soils poses a severe threat to food safety and human health through the food chain. This study investigated the efficacy of tobacco straw-derived biochar, applied at varying rates (0%, 1%, 2%, and 5% w/w), in mitigating Cd accumulation and modulating the growth and nutritional quality of two amaranth (Amaranthus tricolor L.) cultivars (red and green) grown in Cd-contaminated soil (initial total Cd of 2.18 mg/kg). The pot experiment revealed that biochar significantly reduced Cd uptake in both cultivars. Mechanistically, biochar elevated soil pH and drove the in-situ transformation of highly bioavailable exchangeable Cd into the more stable Fe-Mn oxide-bound fraction. Consequently, shoot Cd concentrations were notably suppressed, with the red cultivar exhibiting a superior response; the 2% biochar treatment optimally reduced its shoot Cd concentration by 37.6% compared to the control. Crucially, the amendments induced highly cultivar-specific growth responses. While biochar application simultaneously mitigated Cd toxicity and promoted biomass accumulation in red amaranth (yielding a 58.6% increase in shoot dry weight at the 2% rate), it exerted antagonistic, inhibitory effects on the growth of green amaranth. In conclusion, the incorporation of 2% tobacco straw biochar serves as a highly effective, dual-purpose strategy for significantly reduced health risks and enhancing the yield of red amaranth in Cd-contaminated fields. However, in green amaranth, biochar application induced a physiological trade-off, inhibiting growth despite successful Cd reduction. Furthermore, while Cd concentrations were significantly reduced on a dry-weight basis, future evaluations based on fresh-weight regulatory limits are required to fully confirm food safety. Full article

Urban natural spaces are increasingly promoted as a strategy to strengthen resilience against chronic lifestyle-related diseases associated with urbanization. Among these, urban blue spaces have gained attention for their mitigative, restorative, and instorative health benefits, making their design for health promotion a growing priority in public health and urban planning. This study investigates outdoor gyms (OGs) and their role in promoting physical activity in coastal San Diego, USA. Users’ behavior was examined by employing the System for Observing Play and Recreation in Communities and the Blue Health Behavioral Assessment Tool. Supplementary, an online survey was used to further examine visitors’ perceptions towards the OGs of our study area and which design characteristics might affect their use. Systematic observation showed that OGs accounted for 28% of vigorous physical activity onsite, suggesting they function as a co-equal component of the physical activity affordance mix. Community members viewed the gyms as cost-effective and valuable additions to the blue space, while noting that design characteristics influence their use. Ocean views, proximity to amenities, and the availability of accessible equipment emerged as key enabling factors. These findings offer actionable insights for local stakeholders and underscore the importance of community co-design in realizing the health potential of urban blue spaces. Full article

Collagen is a key structural protein of the skin, essential for maintaining its mechanical strength, elasticity, and hydration. Oral collagen supplementation, particularly in the form of collagen peptides, has recently gained significant interest as a nutritional strategy to support skin health and overall wellbeing. However, the evidence regarding its effectiveness in supporting skin health and improving hair, nail, and wound-healing outcomes remains heterogeneous. The aim of this review is to summarize and critically evaluate the current human evidence on oral collagen supplementation and its potential role in supporting skin health, hair and nail quality, and wound healing. A targeted literature search was conducted using PubMed and Web of Science to identify clinical trials and relevant studies assessing the effects of collagen supplementation on skin aging parameters, including elasticity, wrinkles, hydration, and barrier function, as well as hair loss, nail disorders, and wound healing. Collagen-derived peptide supplementation has been associated with improvements in skin hydration, elasticity, wrinkle appearance, and dermal extracellular matrix organization, while also supporting hair thickness and strength, modestly enhancing nail growth, and promoting wound healing. Benefits are most consistent with low-molecular-weight hydroxyproline-rich peptides, with peptide characteristics appearing more important than collagen source. Evidence is limited by short study durations, heterogeneous designs, multi-ingredient formulations, and industry funding, which reduce confidence in the magnitude and consistency of the reported effects. Nevertheless, high-quality, long-term, independently funded trials with standardized outcomes are still required to confirm these findings. Full article

Hydrogen-rich water (HRW) has growth-promoting, antioxidant, anti-inflammatory, and microbiota-modulating properties; however, its effects on juvenile snakeheads (Channa argus) remain underexplored. In this experiment, we investigated the effects of HRW on the antioxidant capacity, immune response, and gut microbiota of juvenile snakeheads. A total of 360 fish (15.32 ± 0.50 g) were randomly assigned to three groups: a control group (aerated water), a low-hydrogen group (H1, 280 ± 50 ppb), and a high-hydrogen group (H2, 550 ± 50 ppb). The results revealed that, compared with the control group, H1 significantly reduced serum levels of total protein, triglycerides, glucose, and urea nitrogen (P < 0.05). In the liver, H1 upregulated tir-2 expression and downregulated tnf-α expression (P < 0.05). Furthermore, serum SOD activity was significantly increased in both H1 and H2 groups compared with the control (P < 0.05), while serum CAT activity was significantly elevated only in the H2 group (P < 0.05). No significant alteration was detected in intestinal morphology (P > 0.05), and similarly, digestive enzyme activity did not change significantly (P > 0.05). Regarding gut microbiota, the H1 group increased the relative abundance of Actinobacteria (P < 0.05); at the genus level, it decreased the abundance of Acinetobacter and Pseudomonas, while increasing the abundance of Agathobacter, Faecalibacterium, and Anaerostipes (P < 0.05). In summary, our findings revealed that optimal HRW supplementation enhances immunomodulatory and antioxidant functions and improves intestinal health, thereby establishing HRW as a promising functional water conditioner for sustainable aquaculture applications. Full article

Against the backdrop of rapid urbanization and climate warming, the urban heat island (UHI) effect has severely affected ecological security and public health. Existing studies have often focused on single-city analyses or large-sample averages, with insufficient attention to the nonlinear driving mechanisms of UHI under different hydrothermal contexts. This study selects Wuhan and Xi’an as representative cities, constructing an explainable machine learning framework to interpret and compare UHI intensity across feature importance, nonlinear responses, factor interactions, and spatial differentiation. The results show that, in Wuhan, the top five factors contribute 62.4%, reflecting a composite dominance of ecology, spatial morphology, location, and human activities. In Xi’an, the top five factors contribute 72.0%, indicating a more concentrated dominant structure. Nonlinear responses reveal that key factors like NDVI have distinct effect thresholds and mechanisms in the two cities. Spatially, Wuhan displays a continuous gradient pattern characterized by center-promoting and peripheral-suppressing effects, whereas Xi’an presents a block-like mosaic structure composed of multiple juxtaposed districts. These differences suggest that UHI mitigation should move beyond a uniform control model and instead adopt climate-sensitive strategies that account for the dominant factor combinations, response thresholds, and spatial organization of each city. The proposed framework and findings provide scientific support for understanding UHI mechanisms under different hydrothermal contexts and offer targeted implications for thermal environment regulation and spatial planning in cities with similar climatic and environmental characteristics. Full article

Background: The COVID-19 pandemic was accompanied by an infodemic that promoted the use of so-called “miracle products” lacking scientific evidence, posing significant public health risks. Despite increasing concern, evidence on effective educational strategies to counteract this misinformation remains limited, particularly in Latin America. Methods: A quasi-experimental pre–post study without a control group was conducted among university students in Mexico City between February and June 2021. Participants were recruited via Facebook using a snowball sampling approach. A validated nine-item questionnaire assessed knowledge about miracle products before and after exposure to an educational video intervention. Paired statistical analyses were performed to evaluate changes in knowledge. Results: A total of 157 participants completed the pre-test, and 103 completed the post-test. The intervention resulted in a significant increase in knowledge scores, from a mean of 5.98 (SD = 1.73) to 9.05 (SD = 1.54) (p < 0.001). Significant improvements were observed in eight of nine items, with the largest increases in knowledge related to high-risk substances and reporting mechanisms. No significant baseline differences were found between participants who completed and those who did not complete the post-test. Conclusions: The video-based educational intervention was effective in improving knowledge about miracle products during COVID-19. These findings support the use of digital health education strategies as scalable tools to combat misinformation, particularly in resource-constrained settings. However, further research using controlled designs is needed to assess long-term effects and behavioral outcomes. Full article

This study assessed the effects of dietary honeycomb supplementation on laying performance, intestinal inflammation, ovarian function, and yolk precursor synthesis in laying hens. A total of 320 Dawu Golden Phoenix laying hens (288-d-old) were randomly assigned into four treatment groups with eight replicates of 10 hens each. Hens were provided diets containing 0, 0.5, 1.0, or 2.0 g/kg honeycomb for 30 d. Dietary honeycomb significantly increased average egg weight, average daily feed intake, and laying rate, while decreasing the feed conversion ratio (p < 0.05). It enhanced serum antioxidant capacity, as reflected by higher GSH, SOD, and CAT activity (p < 0.05). Meanwhile, honeycomb modulated the expression of Nrf2/Keap1 pathway-related genes, accompanied by increased expression of downstream antioxidant-related genes. Additionally, honeycomb downregulated intestinal inflammatory- and apoptosis-related factors (p < 0.05), which effectively alleviated intestinal inflammation responses. In the liver, honeycomb showed favorable histological changes, including fewer lipid droplets and less vacuolar degeneration. Furthermore, it decreased serum ALT, AST, and TG levels and promoted yolk precursor synthesis by upregulating genes associated with lipid transport and vitellogenesis (p < 0.05). In the ovary, honeycomb optimized ovarian morphology and follicle development; elevated serum FSH, E2, and MLT levels; and enhanced the expression of steroidogenesis-related genes (p < 0.05), thereby promoting steroid hormone synthesis and reducing follicular atresia. In conclusion, dietary honeycomb supplementation could maintain intestinal health, modulate hepatic and ovarian metabolism functions, promote yolk precursor synthesis, improve follicle development, and consequently, enhance the laying performance of hens. Full article

The global push to eliminate antibiotic growth promoters in poultry has accelerated the demand for effective natural alternatives. β-Glucans—branched polysaccharides derived from Saccharomyces cerevisiae cell walls—enhance immunity and gut health; however, their mechanistic effect on the somatotropic axis and meat quality in broilers remains unresolved. Herein, the hypothesis that dietary β-glucan modulates somatotropic signaling to improve growth performance and breast muscle quality was tested with 240 one-day-old Ross 308 chicks allocated to three groups—untreated control, 250 mg β-glucan/kg feed, and 1 g β-glucan/kg feed—and reared for 35 d. Growth performance, plasma growth hormone (GH) and prolactin (PRL), somatotropic axis gene expression in liver and breast muscle, and postmortem meat quality were assessed. β-Glucan supplementation significantly elevated final body weight, breast muscle weight, and plasma GH and PRL, and upregulated hepatic IGF-1 and muscle GH receptor mRNA at 35 d, and hepatic GH receptor mRNA at 17 d. Muscle pH was higher and relative drip loss lower in supplemented birds 72 h postmortem. These results support the hypothesis and identify 1 g β-glucan/kg feed as an effective dose for improving growth and meat quality through somatotropic axis modulation—a novel mechanistic demonstration in broiler chickens. Full article

Medium-chain triglycerides (MCTs) are functional lipids with unique physicochemical properties and metabolic advantages. Recently, their regulatory roles in various chronic diseases have attracted considerable attention. This review systematically summarizes recent research progress and the proposed mechanisms of MCTs and their metabolites in metabolic diseases, neurological disorders, gut health, and muscle function. In the metabolic field, MCTs offer potential nutritional strategies for managing obesity, type 2 diabetes mellitus (T2DM), and various metabolic liver diseases. These effects are primarily mediated by improving insulin sensitivity, regulating lipid metabolism, and modulating energy expenditure. In neurological diseases, MCTs demonstrate potential for preventing and treating Alzheimer’s disease (AD), Parkinson’s disease (PD), and epilepsy through multiple pathways, including ketogenic energy supply, anti-inflammatory and antioxidant effects, and mitochondrial protection. Regarding gut health, MCTs and their derivatives may benefit digestive health by modulating gut microbiota and enhancing barrier function. For muscle health, MCTs help optimize energy metabolism and protein homeostasis, showing promise for countering sarcopenia and improving exercise performance. In conclusion, the prospects for MCTs are broad. Future research should focus on promoting their scientific application in precision nutrition and disease therapy, and more rigorous clinical trials are needed to confirm their efficacy and safety. Full article

Background: Suryanamaskar (Sun Salutation) is a dynamic sequence of yoga that incorporates movement, breath and mindfulness, and is known for its many potential multidimensional health benefits. Despite the increasing volume of research, a comprehensive and domain-specific synthesis examining the multidimensional effects of Suryanamaskar and yoga-based interventions incorporating Suryanamaskar remains limited. Hence, the present study was designed to systematically review and synthesize the existing evidence related to the effects of Suryanamaskar and yoga-based interventions using Suryanamaskar sequence on various populations and outcome domains. Methods: This systematic review was conducted in accordance with the PRISMA 2020 statement and Cochrane Handbook recommendations. Literature searches were performed in PubMed, Scopus, Web of Science, and Google Scholar from database inception to 31 December 2025. Studies involving human participants and Suryanamaskar-based interventions reporting measurable physical, physiological, or psychological outcomes were included. Fourteen studies met the eligibility criteria. Study characteristics, intervention protocols, and outcome measures were extracted. Risk of bias was assessed using RoB 2 for randomized studies and ROBINS-I for non-randomized studies. Due to substantial heterogeneity, findings were synthesized narratively. Results: A total of 14 studies met the inclusion criteria. Overall, Suryanamaskar and yoga-based interventions incorporating Suryanamaskar were associated with improvements in physical fitness, physiological health, psychological well-being, and body composition across diverse populations. Most included studies reported favourable changes in physical fitness, physiological, psychological, and body-composition outcomes; however, the magnitude and consistency of findings varied substantially across study designs, participant populations, intervention protocols, and outcome measures. Conclusions: Promising but heterogeneous evidence suggests that Suryanamaskar and yoga-based interventions incorporating Suryanamaskar may contribute to improvements in physical fitness, physiological function, psychological well-being, and body composition across diverse populations. However, these findings should be interpreted with caution because of variability in study designs, intervention protocols, participant characteristics, and risk of bias. Although Suryanamaskar appears to be a practical, low-cost, and holistic intervention with potential applications in educational, sports, and health-promotion settings, further high-quality randomized controlled trials with standardized protocols and larger sample sizes are required to strengthen the evidence base. Full article

Background: Education and employment are widely promoted as pathways to reducing intimate partner violence (IPV) through enhanced economic independence and bargaining power. However, evidence from settings characterised by entrenched gender inequalities suggests that these structural factors may not uniformly translate into protection. This study examines whether education and employment are associated with women’s experiences of IPV in South Africa. Methods: This study utilised nationally representative data from the South Africa Demographic and Health Survey (N = 2354). Education and employment were used as structural proxies for women’s socioeconomic positioning. Survey-adjusted logistic regression models were employed to estimate associations between these factors and lifetime IPV, controlling for key sociodemographic characteristics. Given the cross-sectional design and the use of lifetime IPV alongside contemporaneous measures of education and employment, findings are interpreted as associative rather than causal. Results: Education and employment were not significantly associated with women’s likelihood of experiencing IPV. Women with these characteristics were not less likely to report emotional, physical, or sexual violence compared to those without them. IPV prevalence was higher among women aged 25–34, those with secondary education, and those in lower wealth households. Marital status emerged as a strong correlate, with separated and divorced women facing substantially higher odds of IPV. Discussion: The absence of a significant association suggests that education and employment alone may be insufficient to reduce IPV risk in contexts where gender norms and relational power imbalances remain entrenched. These findings may also reflect the limitations of using structural indicators as proxies for empowerment, as such measures do not capture decision-making power, control over resources, or intra-household dynamics. Conclusions: Interventions to reduce IPV should extend beyond improving women’s access to education and employment to address relational, normative, and structural drivers of violence. Multidimensional approaches that incorporate gender-transformative strategies and strengthen women’s substantive agency are likely to be more effective. Full article

Edible and medicinal mushrooms, including cultivated and wild species, are increasingly recognized as valuable functional foods and nutraceutical resources due to their high nutritional value, abundance of bioactive compounds, and documented health-promoting properties. However, their high perishability results in substantial postharvest quality losses and limits commercial shelf life. This review provides a comprehensive overview of recent advances in mushroom preservation technologies, with particular emphasis on emerging non-thermal approaches such as cold plasma treatment, active packaging systems, and electrostatic field technologies. Conventional and advanced drying methods, edible coatings, biopreservation, fermentation and irradiation are also critically evaluated. Cold plasma treatment effectively reduces microbial contamination and enzymatic browning while maintaining firmness and nutritional quality, whereas active packaging systems based on chitosan films, nanocomposites, and modified atmospheres help reduce moisture loss, delay senescence, and preserve physicochemical properties during storage. Electrostatic field treatment combined with modified atmosphere packaging has shown additional potential for extending refrigerated shelf life. Among drying technologies, freeze-drying generally provides the highest retention of colour, texture and bioactive compounds, although its industrial application remains constrained by high energy consumption and operational costs. Overall, current evidence suggests that integrated preservation approaches offer the greatest potential for improving shelf-life extension and quality retention. Nevertheless, further research is required to address challenges related to industrial scalability, process standardization, economic feasibility and long-term quality assessment. Full article

(1) Background: Previous school-based interventions have addressed adolescent health behaviors such as physical activity, screen time, and sleep, but have predominantly targeted these behaviors independently rather than simultaneously. The Erasmus+ project FiTeens developed an integrated intervention combining theoretical content, videos, infographics, and interactive tasks to promote multiple health behaviors concurrently. The objective of the current article is to present the protocol for a school-based intervention study designed to examine the effects of the FiTeens program on adolescents’ physical activity, screen time, and sleep behaviors. We hypothesize that students receiving the FiTeens intervention will demonstrate increased physical activity, reduced screen time, and improved sleep outcomes compared with students in the control group. (2) Methods: Teachers will be introduced to the FiTeens tools prior to delivering the intervention to students in grades 5–9. Students will participate in an eight-week intervention program combining structured lessons and behavior-change challenges. Primary outcomes include changes in physical activity, screen time, and sleep duration and quality. Secondary outcomes include psychological determinants such as motivation and behavioral intentions. Data will be collected at baseline and at 1-, 3-, and 6-month follow-ups and analyzed using repeated measures ANOVA. (3) Expected results: The study will evaluate whether the intervention may contribute to improvements in health-related behaviors among adolescents, including increased physical activity, reduced screen time, and improved sleep outcomes. (4) Conclusions: The intervention based on FiTeens tools could have the potential to promote healthier lifestyle behaviors among students by increasing physical activity during leisure time, supporting the effective limitation of screen time and enhancing bedtime routines to improve sleep quality. Full article

Background: As population aging accelerates, maintaining functional independence among older adults has become a critical public health priority. Cognitive function is a well-established determinant of instrumental activities of daily living (IADL); however, the role of digital literacy in shaping this relationship remains unclear. In the context of increasing digitalization, digital literacy may serve as a key factor supporting aging in place. Therefore, this study aimed to examine the moderating effect of digital literacy on the relationship between cognitive function and IADL among community-dwelling older adults. Methods: This descriptive cross-sectional study was conducted among 147 community-dwelling older adults aged 75 years and older. Cognitive function was assessed using the Korean version of the Montreal Cognitive Assessment (MoCA-K), IADL was measured using the Korean Instrumental Activities of Daily Living (K-IADL) scale, and digital literacy was evaluated using an 11-item dichotomous scale. Data were analyzed using descriptive statistics, Pearson’s correlation analysis, and hierarchical regression analysis. The moderating effect of digital literacy was tested using the PROCESS macro. Results: Cognitive function was positively correlated with digital literacy (r = 0.56, p < 0.001) and IADL (r = 0.26, p < 0.001), and digital literacy was also positively correlated with IADL (r = 0.25, p < 0.001). In the regression analysis, cognitive function significantly predicted IADL (B = 0.11, p = 0.004), but this effect became non-significant after including digital literacy in the model. A significant moderating effect of digital literacy was observed (B = −0.03, p < 0.001). Conditional effects analysis revealed that cognitive function significantly influenced IADL only among older adults with low levels of digital literacy (B = 0.12, p = 0.005), whereas no significant effect was found at moderate or high levels of digital literacy. Conclusions: Digital literacy significantly moderates the relationship between cognitive function and ADL among community-dwelling older adults. These findings suggest that digital literacy may function as a compensatory mechanism that mitigates the impact of cognitive decline on daily functioning. Enhancing digital literacy may represent an effective strategy to promote functional independence and support aging in place in an increasingly digital society. Full article