3,191 Results Found

Emerging studies have suggested several chromosomal regions as potential host genetic factors involved in the susceptibility to SARS-CoV-2 infection and disease outcome. We nested a COVID-19 genome-wide association study using the GR@ACE/DEGESCO stud...

Background: Health literacy (HL) is a key determinant of health outcomes and equity. The European Health Literacy Survey 2019 (HLS₁₉) introduced three domain-specific instruments—HLS₁₉-NAV, HLS₁₉-COM-P-Q11, and HLS₁₉-VAC. We present the transla...

Graphene (Gr) has proved its significant role as a reinforcement material in improving the strength of metal matrix composites due to its excellent mechanical properties. In this paper, Gr/Cu composite film with a layered structure was prepared by la...

Cortisol, a stress hormone, plays key roles in mediating stress and anti-inflammatory responses. As abnormal cortisol levels can induce various adverse effects, screening cortisol and cortisol analogues is important for monitoring stress levels and f...

Due to its superior mechanical properties, graphene (Gr) has the potential to achieve high performance polymer-based nanocomposites. Previous studies have proved that defects in the Gr sheets could greatly reduce the mechanical properties of Gr, whil...

The setae structure of geckos’ toes can create a strong adhesion force, allowing geckos to climb almost vertical walls. Inspired by this, carbon nanotubes–graphite (CNTs-Gr) was prepared by microwave technology, where CNTs like the setae...

The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is the presence of poly-PR/GR dipeptide repeats, which are encoded by the chromosome 9 open reading frame 72 (C9orf72) gene. Recently, it was shown...

Under an internet background involving artificial intelligence and big data—unstructured, materialized, network graph-structured data, such as social networks, knowledge graphs, and compound molecules, have gradually entered into various specif...

Glucocorticoid receptor (GR), which is ubiquitously expressed in nearly all cell types of various organs, mediates the tissue-specific metabolic and immune responses to maintain homeostasis and ensure survival under stressful conditions or pathologic...

GR-2397 (previously VL-2397, ASP2397) is a first-in-class antifungal agent for the treatment of invasive aspergillosis. This siderophore-like molecule resembles ferrichrome; however, it is differentiated by three amino acid changes and an aluminum ra...

The glucocorticoid receptor (GR, also known as NR3C1) coordinates molecular responses to stress. It is a potent transcription activator and repressor that influences hundreds of genes. Enhancers are non-coding DNA regions outside of the core promoter...

Considering persistent years, many researchers continuously seek an optimum way to utilize the idea of magnetorheology (MR) materials to be practically used for everyday life, particularly concerning resistivity sensing application. The rheology and...

The austenitization kinetics of SA508 Gr.3 steel during heating was studied using the isoconversional method combined with continuous thermal dilatometric tests for the first time. The model-free austenitization kinetics was built and the effective a...

A series of creep–fatigue tests of Gr.91 steel were performed at 600 °C. Fatigue life was reduced by tensile strain holding. The minimum life reduction factor was approximately 0.3. The creep–fatigue life could not be estimated proper...

Although in vitro sensors provide facile low-cost ways to screen for biologically active targets, their results may not accurately represent the molecular interactions in biological systems. Cell-based sensors have emerged as promising platforms to s...

As-received Gr.91 steel tube was normalized at either 940 or 1060 °C for 1 h, followed by Ar-assisted cooling to room temperature, then tempered at 760 °C for 2 h. Those samples were designated as 940NT or 1060NT samples. An infrared heating...

Hg(II), as an extremely hazardous heavy metal contaminant in the environment, poses a significant potential hazard to human health and ecosystems. A GR-MWCNTs-COOH/CeO₂/Nafion composite film-modified glassy carbon electrode was prepared using the dro...

The facture and fatigue behaviour of welded joints made of A516 Gr 60 was analysed, bearing in mind their susceptibility to cracking, especially in the case of components which had been in service for a long time period. With respect to fracture, the...

The presence of clays in copper minerals has a significant negative impact during their processing, leading to low recoveries during the flotation process. In saline environments, the presence of these clays promotes operational problems associated w...

Plant-based milk alternatives represent a growing sector of the functional food industry due to consumer demand for more nutritious and sustainable options. Soymilk is abundant in fibre, phytosterols, and isoflavones. In contrast, cow milk has a high...

Lactobacillus rhamnosus GR-1 is a probiotic that has been shown to reduce the risk of urogenital problems and urinary tract infections. Rice pudding is a popular gluten-free dairy product, and could be a vehicle to deliver L. rhamnosus GR-1 to a broa...

Artificial neural networks (ANNs) have recently gained popularity as useful models for grouping, clustering, and analysis in a wide range of fields. An ANN is a kind of machine learning (ML) model that has become competitive with traditional regressi...

Plant-based beverages are growing in popularity due to the rise of vegetarianism and other health trends. A probiotic almond beverage that combines the properties of almonds, inulin, and Lacticaseibacillusrhamnosus GR-1 may meet the demand for a non-...

In the complex tumor microenvironment, cancer stem cells (CSCs), a rare population of cells, are responsible for malignant tumor initiation, metastasis, drug resistance and recurrence. Controlling breast CSCs (BCSCs) using natural compounds is a nove...

The effect of peak temperatures on the grain growth, microstructure transformation and Vickers hardness of the weld coarse grain heat-affected zone (CGHAZ) of SA508 Gr.4N steel for nuclear reactor pressure vessel was studied. The results show that di...

The SA516 Gr.70 steel possessing excellent toughness and plasticity has been widely used in the cryogenic field. However, the appearance of coarse bainite in the heat affected zone (HAZ) of the fusion welded joint deteriorates the toughness and ducti...

Typically, probiotics are consumed in dairy based products such as yogurt. However, given the rise in various diet types, non-dairy alternatives have been developed, such as inoculating fruit juices with probiotics. Lactobacillus rhamnosus GR-1 is a...

In euryhaline teleost black porgy, Acanthopagrus schlegelii, the glucocorticoid receptor (gr), growth hormone receptor (ghr), prolactin (prl)-receptor (prlr), and sodium–potassium ATPase alpha subunit (α-nka) play essential physiological...

Traditional human-computer interaction technology relies heavily on input devices such as mice and keyboards, which limit the speed and naturalness of interaction and can no longer meet the more advanced interaction needs of users. With the developme...

With the aging trend in megacities, the travel behaviors of the elderly have attracted much attention. Accurate prediction of the travel behaviors of the elderly is a key link to meet the traffic demand and public facilities’ optimization. The...

Bovine alphaherpesvirus 1 (BoHV-1) acute infection leads to latently infected sensory neurons in trigeminal ganglia. During lytic infection, the immediate early expression of infected cell protein 0 (bICP0) and bICP4 is regulated by an immediate earl...

Copper is a mineral element, which is necessary for the normal growth and development of plants, but high levels of copper will seriously damage plants. Studies have shown that AtGR1 improves the tolerance of Arabidopsis to aluminum and cadmium stres...

Pure aluminium poses inferior properties that limit its use in load-bearing applications. Reinforcing multiwall carbon nano-tube (solid lubricant) and graphene to aluminium matrix offers better (antifriction, hardness, and wear resistance) properties...

The present research used the stir-casting method to develop an Al-based composite. The developed composite exhibited challenges while being processed on conventional machining. Thus, a non-traditional machining process was opted to process the compo...

We clear up an ambiguity in the statement of the GRS statistic by providing the correct formula of the GRS statistic and the first proof of its F-distribution in the general multiple-factor case. Casual generalization of the Sharpe-ratio-based interp...

The management of water resources requires as a first step the modeling of rainfall-runoff. It allows simulating the hydrological behavior of the basin for a good evaluation of the potentiality of this in terms of water production. There are differen...

GR24, a synthetic strigolactone analogue, plays a crucial role in a wide range of life processes. Studying the effects of the pre-harvest application of GR24 on strawberry ripening and fruit quality provides a scientific basis for the application of...

The determination of plant growth regulators is of great importance for the quality monitoring of crops. In this work, 4-bromophenoxyacetic acid (4-BPA), one of the phenoxyacetic acids, was detected via the electrochemical method for the first time....

This study aimed to explore the prevalence of learning disabilities (LDs) and the emotional–behavioral difficulties in 208 children from the Crete region in Greece, and who voluntarily presented themselves for study and were evaluated by a univ...

The geosynthetic reinforced soil (GRS) bridge abutment with a staged-construction full height rigid (FHR) facing and an integral bridge (IB) system was developed in Japan in the 2000s. This technology offers several advantages, especially concerning...

Empoasca onukii Matsuda is a primary pest of the tea plant Camellia sinensis (L.) O. Ktze that severely influences the production and quality of tea products. Gustatory receptors (GRs) are an indispensable part of the E. onukii chemosensory machinery...

Hydrological nonstationarity has brought great challenges to the reliable application of conceptual hydrological models with time-invariant parameters. To cope with this, approaches have been proposed to consider time-varying model parameters, which...

Modular Geogrid Reinforced Soil (GRS) retaining walls, as flexible structures, usually have a certain deformation capacity. However, the deformation damage of the facing panels will directly affect the durability performance of the retaining wall and...

The p38 MAPK is a signaling pathway important for cells to respond to environmental and intracellular stress. Upon activation, the p38 kinase phosphorylates downstream effectors, which control the inflammatory response and coordinate fundamental cell...

In large public places such as railway stations and airports, dense pedestrian detection is important for safety and security. Deep learning methods provide relatively effective solutions but still face problems such as feature extraction difficultie...

Gefitinib has been clinically demonstrated to be effective in the first-line setting for patients with advanced EGFR-mutated non-small cell lung cancer (NSCLC). However, acquired therapeutic resistance to gefitinib almost unavoidably develops, posing...

Objectives In Vitro: To study the effects of GR3027 (golexanolone) on neurosteroid-induced GABA-mediated current responses under physiological GABAergic conditions with recombinant human α5β3γ2L and α1β2γ2L GABA_A rec...

Strigolactones (SLs) are classified into plant hormones, playing a key role as a mediator of plant growth in response to several abiotic stresses, including drought and salinity. However, the role of SLs in cadmium (Cd)-induced stress to plants is st...

The rac-GR24, an artificial analog of strigolactone, is known for its roles in inhibiting branches, and previous studies have reported that it has a certain mechanism to relieve abiotic stress, but the underlying metabolic mechanisms of mitigation fo...

Railway communication is undergoing a transitional period worldwide, and 5G for railway (5G-R), which has been adopted by the Railway International Union (UIC) in China and in many other countries, which is a common concern all over the world. The 21...