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Search Results (2,164)

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Keywords = fatigue test methods

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13 pages, 4277 KB  
Article
Short-Term Recovery Interventions Using Cryosauna, Cold-Water Immersion, and Foam Rolling in Mixed Martial Arts Athletes: A Polish Pilot Study
by Behnam Boobani, Juris Grants, Hubert Makaruk, Dariusz Gierczuk, Tomasz Sacewicz, Marcin Starzak, Žermēna Vazne, Tatjana Glaskova-Kuzmina and Artur Litwiniuk
Sports 2026, 14(6), 244; https://doi.org/10.3390/sports14060244 - 12 Jun 2026
Abstract
Background: Mixed martial arts (MMA) involve repeated high-intensity, explosive actions that cause substantial fatigue, underscoring the importance of effective recovery strategies. Purpose: This pilot study investigated short-term performance responses to different post-exercise recovery interventions in Polish MMA athletes. Methods: Sixteen athletes (14 males [...] Read more.
Background: Mixed martial arts (MMA) involve repeated high-intensity, explosive actions that cause substantial fatigue, underscoring the importance of effective recovery strategies. Purpose: This pilot study investigated short-term performance responses to different post-exercise recovery interventions in Polish MMA athletes. Methods: Sixteen athletes (14 males and 2 females) were randomly assigned to cryosauna (CRYO), cold-water immersion (CWI), foam rolling (FR), or passive recovery (CON), with 4 participants per group. The intervention lasted two weeks, with the assigned recovery intervention applied after each training session. Performance was evaluated before and after the intervention using the countermovement jump (CMJ), isokinetic knee peak torque (flexion and extension), and reactive stress tolerance of the determination test (DT). Data were analyzed using mixed-design ANOVA. Results: CMJ performance improved over time across groups. FR significantly increased knee extension (from 228.67 ± 26.49 N.m to 250.50 ± 22.41 N.m), whereas DT scores significantly increased in the CRYO group (from 247.50 ± 12.50 AU to 291.50 ± 15.61 AU) and significantly decreased in the CON group (from 290.25 ± 24.45 AU to 255.50 ± 24.18 AU). Significant Time × Group interactions were observed for DT (p < 0.001) and knee extension torque (p = 0.008). Conclusions: FR appeared beneficial for knee extension performance, whereas CRYO was associated with improved DT performance. Findings are exploratory and need confirmation in larger, controlled studies. Full article
(This article belongs to the Special Issue Sport-Specific Testing and Training Methods in Youth: 2nd Edition)
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32 pages, 2048 KB  
Article
Performance-Based Assessment of Pakistani Regional Aggregates for Flexible Pavements Using Macro- and Micro-Characterization
by Fazli Karim, Nasir Khan, Md Arifuzzaman and Muhammad Imran Khan
Materials 2026, 19(12), 2535; https://doi.org/10.3390/ma19122535 - 11 Jun 2026
Viewed by 70
Abstract
Aggregates comprise up to 95% of flexible pavement composition, critically influencing performance based on geological source and processing methods. In Pakistan, where approximately 264,175 km of roads carry 96% of inland freight, premium Margalla aggregates face increasing demand and depleting reserves, necessitating sustainable [...] Read more.
Aggregates comprise up to 95% of flexible pavement composition, critically influencing performance based on geological source and processing methods. In Pakistan, where approximately 264,175 km of roads carry 96% of inland freight, premium Margalla aggregates face increasing demand and depleting reserves, necessitating sustainable alternatives. This study comprehensively evaluates aggregates from five key quarries (Margalla, Malakand, Kohat, Swabi, and Besai) for highway suitability. Rigorous laboratory testing encompassed macro-level physical and mechanical properties and micro-characterization using Scanning Electron Microscopy (SEM), Energy Dispersive Spectroscopy (EDS), and Fourier Transform Infrared Spectroscopy (FTIR), alongside performance tests including Indirect Tensile Strength (ITS), rutting resistance, and fatigue analysis. Overall, Margalla aggregates exhibited the best performance, showing the lowest abrasion value (21%), highest Tensile Strength ratio (TSR) (82%), highest conditioned ITS (433.7 kPa), highest dynamic modulus (2120 MPa at 25 Hz), and the lowest rut depth (7.8 mm at 10,000 cycles). These superior properties are attributed to their favorable physical characteristics and high calcium content. Malakand and Kohat aggregates also demonstrated satisfactory performance, with TSR values of 79% and 76%, conditioned ITS values of 408.7 and 377.7 kPa, and rut depths of approximately 8.8 and 10.5 mm, respectively, indicating their suitability for medium-traffic pavements. In contrast, Swabi and Besai aggregates exhibited lower moisture resistance (TSR = 77% and 75%), lower conditioned ITS (355.7 and 337.7 kPa), and higher rut depths (~13.0 and 14.2 mm), making them less suitable for high-stress pavement layers. These findings support Malakand and Kohat aggregates as viable regional alternatives to Margalla. Full article
31 pages, 20866 KB  
Article
Synergistic Effect of Stress Relief Holes and Composite Patches on Fatigue Life Extension of Notched Steel Structures
by Paweł J. Romanowicz, Mateusz Pałac and Bogdan Szybiński
Appl. Sci. 2026, 16(12), 5926; https://doi.org/10.3390/app16125926 - 11 Jun 2026
Viewed by 52
Abstract
In the case of notched specimens, the introduction of additional stress relief holes (SRHs), or a local increase in the cross-section stiffness by means of composite overlays, decreases the stress level in the zone of the notch. The synchronous use of SRHs and [...] Read more.
In the case of notched specimens, the introduction of additional stress relief holes (SRHs), or a local increase in the cross-section stiffness by means of composite overlays, decreases the stress level in the zone of the notch. The synchronous use of SRHs and composite patches has not been extensively investigated so far. Therefore, the main objective of the proposed research is to analyse the synergistic effect resulting from the simultaneous application of SRHs and structural reinforcement in the form of composite patches bonded to the bare steel element. The influence of this approach is investigated with the use of the finite element solution and experimental fatigue tests. As a result, a reduction in the stress concentration by almost 28% with respect to the bare plate with a hole was received. The use of composite overlays increases fatigue life by over 700% at the same cyclic tensile load in comparison with specimens without reinforcement and SRHs (base configuration). The use of reinforcement overlays or the synergetic application of overlays and SRHs guaranteed higher fatigue life (five and 10 times, respectively) at a higher load (by approximately 11%) compared to the base configuration. This confirmed the synergetic and positive influence of both modifications used in parallel. Full article
(This article belongs to the Special Issue Fatigue and Fracture Behavior of Engineering Materials)
20 pages, 10213 KB  
Article
GA/KH792 Surface Chemical Co-Modification for Enhancing Performance and Interfacial Properties of PET Fiber-Reinforced Asphalt Mastic
by Yingdong Zhao, Jiefen Kang, Yanan Guo, Yongling Ding, Huiling Yu, Qinxi Dong, Huadong Sun, Wenshu Cheng, Shuhua Song, Hong Yin and Kunpeng Zhao
Coatings 2026, 16(6), 703; https://doi.org/10.3390/coatings16060703 (registering DOI) - 11 Jun 2026
Viewed by 113
Abstract
Polyester (PET) fibers are widely used to reinforce asphalt materials; however, their smooth and hydrophobic surfaces limit interfacial bonding and restrict their reinforcing efficiency. This study develops an eco-friendly surface modification method based on the chemical modification of gallic acid (GA) and aminosilane [...] Read more.
Polyester (PET) fibers are widely used to reinforce asphalt materials; however, their smooth and hydrophobic surfaces limit interfacial bonding and restrict their reinforcing efficiency. This study develops an eco-friendly surface modification method based on the chemical modification of gallic acid (GA) and aminosilane (KH792) to enhance the compatibility between PET fibers and asphalt. Modified fibers with various molar ratios of GA/KH792 were prepared and incorporated into asphalt mastic. Their performance was evaluated using softening point, cone penetration, dynamic shear rheometer (DSR), multiple stress creep recovery (MSCR), linear amplitude sweep (LAS), and bending beam rheometer (BBR) tests, combined with interfacial interaction analysis and scanning electron microscopy (SEM). The results show that surface modification significantly improves the reinforcing effect of PET fibers. In particular, the co-modified fiber with a GA/KH792 ratio of 1:1 exhibits the best performance, with increases of 27% in softening point and 105% in shear strength, as well as notable improvements in rutting resistance, fatigue performance, and temperature stability. Interfacial indices and SEM observations confirm enhanced adhesion, dispersion, and load transfer capacity. However, the improvement in low-temperature performance is limited. Overall, GA/KH792 chemical modification effectively enhances fiber asphalt interfacial interaction and provides a simple and sustainable approach for developing high-performance asphalt materials. Full article
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21 pages, 2471 KB  
Article
Prediction of the Remaining Life of Rolling Bearings Based on Health Indicators and Temporal Attention Networks
by Jiale Bai and Hailong Deng
Appl. Sci. 2026, 16(12), 5871; https://doi.org/10.3390/app16125871 - 10 Jun 2026
Viewed by 87
Abstract
Accurate remaining useful life (RUL) prediction of rolling bearings was essential for condition-based maintenance because bearing service degradation was primarily governed by progressive rolling-contact fatigue at the rollingelement–raceway interface, whereas vibration signals provided measurable responses to this degradation rather than being its physical [...] Read more.
Accurate remaining useful life (RUL) prediction of rolling bearings was essential for condition-based maintenance because bearing service degradation was primarily governed by progressive rolling-contact fatigue at the rollingelement–raceway interface, whereas vibration signals provided measurable responses to this degradation rather than being its physical cause. However, reliable RUL prediction remained challenging because vibration measurements were noisy, nonlinear, stage-dependent, and sensitive to operating-condition shifts. In this study, a health-indicator-guided temporal-attention framework was developed for bearing RUL prediction using public run-to-failure vibration datasets. The novelty of this work lay in integrating degradation-consistent health indicator construction, sliding-window life-cycle representation, and HI-guided temporal attention into a unified and interpretable prediction framework. First, degradation-sensitive vibration features were extracted and fused into a compact health indicator (HI) to represent the progressive deterioration trend. Then, sliding-window sequences were generated and processed by a Transformer-based temporal-attention network, through which long-range temporal dependencies were captured and higher weights were assigned to informative degradation segments near stage transitions and late-life acceleration. Experiments on the XJTU-SY and IMS datasets showed that the proposed method improved prediction stability, reduced late-life error amplification, and achieved better performance than baseline variants without HI or temporal attention. Ablation analysis confirmed that HI construction mitigated cross-stage drift, whereas temporal attention enhanced transition sensitivity during accelerated degradation. Robustness and cross-domain tests further indicated that the method maintained acceptable degradation-following behavior under noise perturbations and operating-condition changes, although explicit domain-adaptation mechanisms were still required for strongly shifted target domains. Full article
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29 pages, 1713 KB  
Article
Preparation and Rheological Properties of Waterborne Epoxy Resin Emulsified Asphalt
by Siyu Wu, Huaxin Chen, Suining Zheng, Yonglu Dong and Wenlan Zhang
Materials 2026, 19(12), 2493; https://doi.org/10.3390/ma19122493 - 10 Jun 2026
Viewed by 137
Abstract
To address the lack of systematic quantitative studies on waterborne epoxy resin (WER)-modified emulsified asphalt regarding its rheological optimization and engineering applicability, this study fills the gap by preparing WER-modified emulsified asphalt via a two-step process. New findings reveal that 20% WER content [...] Read more.
To address the lack of systematic quantitative studies on waterborne epoxy resin (WER)-modified emulsified asphalt regarding its rheological optimization and engineering applicability, this study fills the gap by preparing WER-modified emulsified asphalt via a two-step process. New findings reveal that 20% WER content significantly enhances elastic components, creep–recovery, fatigue life, and fracture energy. The main objective is to establish a theoretical basis for high-performance pavement materials. Modified emulsified asphalt specimens with different waterborne epoxy resin contents were prepared using a two-step method of “emulsification followed by compounding”. The stability of the emulsions was quantitatively evaluated by zeta potential, storage stability, particle size distribution, and demulsification time. Their rheological parameters, multi-stress creep–recovery characteristics, fatigue life, and low-temperature crack resistance were systematically tested across the full temperature range using a dynamic shear rheometer and a bending beam rheometer. In addition, the bonding performance, strength development behavior, and water resistance durability were comprehensively assessed through pull-out tests, Marshall stability and splitting strength tests, as well as freeze–thaw cycle tests. These properties were compared with those of unmodified emulsified asphalt (UEA-0) and SBR-modified emulsified asphalt (SBR-EA). With an increase in waterborne epoxy resin content, the elastic component of the modified asphalt improved significantly, and the phase angle continuously decreased. The specimen with 20% waterborne epoxy resin content (WER-EA-20) exhibited the best performance: its phase angle was lower than those of the other groups under high-, medium-, and low-temperature conditions. After seven creep–recovery cycles, its creep–recovery rate remained at 33%, substantially higher than the 8% observed for the unmodified specimen. The fatigue life reached 15,000 cycles under a shear stress of 2.1 MPa. At −10 °C, the fracture strength was 0.92 MPa, and the fracture energy reached 21.4 J. Furthermore, the pull-out strength of WER-EA-20 was 0.86 MPa, with the failure mode identified as asphalt cohesive failure. After 37 days of curing, the Marshall stability reached 22.5 kN, and the splitting strength was 1.36 MPa. After 40 freeze–thaw cycles, the freeze–thaw splitting strength ratio (TSR) of WER-EA-20 remained above 75%, representing an improvement of more than 110% compared to the unmodified UEA-0 (TSR ≈ 35.5%), which highlights the significant enhancement in water resistance imparted by the waterborne epoxy resin. Compared to SBR-EA, WER-EA-20 has a higher softening point, a lower suitable mixing temperature, and better anti-aging properties. Waterborne epoxy resin can effectively improve the viscoelastic properties and overall road performance of emulsified asphalt, and the modification effect increases with increasing dosage. Full article
(This article belongs to the Special Issue Mechanical Dynamics and Rheological Insights in Advanced Materials)
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21 pages, 6186 KB  
Article
Combined Effects of Fast-Melting SBS (F-SBS) and Crumb Rubber (CR) on Asphalt Mixtures Using the Dry Process Method
by Jinyao Li, Hao Wu, Fengqi Guo, Weimin Song, Xiaobao Chen, Hongbo Liao and Zhiqiang Cheng
Polymers 2026, 18(12), 1440; https://doi.org/10.3390/polym18121440 - 9 Jun 2026
Viewed by 182
Abstract
Considering the production efficiency and performance limitations inherent in conventional wet process asphalt mixtures, this study investigates the synergistic potential of fast-melting styrene–butadiene–styrene (F-SBS) and crumb rubber (CR) in enhancing the performance of asphalt mixtures when applied through the dry process modification method. [...] Read more.
Considering the production efficiency and performance limitations inherent in conventional wet process asphalt mixtures, this study investigates the synergistic potential of fast-melting styrene–butadiene–styrene (F-SBS) and crumb rubber (CR) in enhancing the performance of asphalt mixtures when applied through the dry process modification method. Firstly, high- and low-temperature rheological tests were conducted on modified asphalt containing different dosages of F-SBS (1–3%) and CR (1–10%) to determine the optimal dosage of the modifier for the asphalt mixture. Furthermore, a comprehensive comparative analysis was conducted to evaluate the performance of asphalt mixtures modified with conventional SBS/CR against the F-SBS/CR system across both wet and dry modification processes. Finally, microscopic tests were conducted on the modified asphalt and asphalt mixtures to further investigate the synergistic mechanisms and effects of F-SBS and CR. The results indicated that F-SBS (2.5%)/CR (8%)-modified asphalt exhibited superior rheological properties, enhanced compatibility, and improved storage stability. Additionally, the dry process F-SBS/CR asphalt mixture demonstrated a 12.9% improvement in high-temperature stability, a 19.1% improvement in split strength after freeze–thaw cycles, and a 14.4% improvement in fatigue resistance compared to wet process conventional SBS/CR asphalt mixtures. The microscopic test results indicate that F-SBS and CR modify the asphalt primarily through physical blending. Observations further confirm that the dry process enhances interfacial bonding among the modifiers, asphalt binder, and aggregates, promoting closer and more stable interactions and thus improving mixing efficiency and overall performance. This study confirms the advantages of applying F-SBS and CR in dry process asphalt mixtures, thereby providing guidance for establishing a connection between laboratory investigations and field construction practices in the future. Full article
(This article belongs to the Special Issue Mechanical Behaviors of Polymer and Polymer Composites)
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12 pages, 2605 KB  
Proceeding Paper
Design and Development of an Oscillator-Driven Coconut Dried Kernel Scraper for Small Virgin Coconut Oil (VCO) Farmers
by Vicardo J. Aroy, John O. Estillore, Louie Jay P. Manlunas, Jaquelyn L. Quintano and Charlou C. Rivas
Eng. Proc. 2026, 143(1), 1; https://doi.org/10.3390/engproc2026143001 - 8 Jun 2026
Viewed by 197
Abstract
The traditional manual method of removing dried coconut kernels from shells is labor-intensive, time-consuming, and poses a risk of injury to workers. To address these challenges, this study developed an Oscillator-Based Coconut Dried Kernel Scraper to enhance efficiency, safety, and productivity in the [...] Read more.
The traditional manual method of removing dried coconut kernels from shells is labor-intensive, time-consuming, and poses a risk of injury to workers. To address these challenges, this study developed an Oscillator-Based Coconut Dried Kernel Scraper to enhance efficiency, safety, and productivity in the coconut processing industry. The device utilizes an oscillatory mechanism driven by an electric motor to produce a controlled scraping motion, facilitating the effective detachment of the dried kernel from the shell with minimal physical effort. Key components of the prototype include a motor-driven oscillating blade, a kernel-holding fixture, and a safety enclosure. The design emphasizes the use of locally available materials and user-friendly operation. Preliminary testing demonstrated a significant reduction in processing time and operator fatigue compared to manual scraping methods. Furthermore, the researchers conducted a comparative performance evaluation between manual and mechanized scraping, with participants indicating a strong preference for the oscillator-based scraper. The product achieved the highest scores for efficiency and user satisfaction, particularly among small- to medium-scale coconut farmers. Based on these findings, it is recommended that future improvements include enhancements in design and the integration of a capacitive sensor to automate and further refine the control system. Full article
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14 pages, 590 KB  
Article
Complementary Error Patterns Between Human Evaluators and GPT-4o in Video-Based Cardiopulmonary Resuscitation Skills Assessment: Implications for Artificial Intelligence-Assisted Second Reading
by Hye Ji Park, Daun Choi and Choung Ah Lee
J. Clin. Med. 2026, 15(12), 4436; https://doi.org/10.3390/jcm15124436 - 8 Jun 2026
Viewed by 107
Abstract
Background/Objectives: Cardiopulmonary resuscitation (CPR) skill assessments are susceptible to evaluator subjectivity, cognitive fatigue, and observational limitations. Although recent advances in multimodal artificial intelligence have increased the possibility of automated video-based assessment, its validity for clinical skill evaluation remains insufficiently examined. Methods: In [...] Read more.
Background/Objectives: Cardiopulmonary resuscitation (CPR) skill assessments are susceptible to evaluator subjectivity, cognitive fatigue, and observational limitations. Although recent advances in multimodal artificial intelligence have increased the possibility of automated video-based assessment, its validity for clinical skill evaluation remains insufficiently examined. Methods: In this cross-sectional study, we enrolled 130 laypersons who underwent Basic Life Support training and skill testing. Twenty recordings were used for prompt development and 110 recordings were analyzed. Expert evaluators and GPT-4o independently assessed participants’ skills using a 12-item checklist. The manikin sensor data were the reference standard for the four chest compression metrics. Agreement was evaluated using Gwet’s agreement coefficient 1 (AC1) and intraclass correlation coefficient (2,1). Diagnostic accuracy, sensitivity, and specificity were compared using McNemar’s test. Results: Procedural items such as confirming cardiac arrest, calling 119, and requesting an automated external defibrillator showed a near-perfect agreement between experts and GPT-4o (AC1 > 0.8). However, the agreement was poor for the compression depth (AC1 = 0.374) and full chest recoil (AC1 = 0.355). Experts demonstrated high sensitivity (77.8–84.3%) but low specificity (24.6–47.8%), whereas GPT-4o showed low sensitivity (35.6–40.6%) but high specificity (69.2–76.1%). Conclusions: GPT-4o cannot serve as a standalone evaluator because of its inherent limitations in inferring three-dimensional spatial information from two-dimensional videos. However, its high agreement on procedural items and complementary error patterns with that of human evaluators on compression metrics suggests its potential as a decision support tool to mitigate expert leniency bias in CPR education. Full article
(This article belongs to the Special Issue Novel Technologies to Assist Emergency Medical Care)
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17 pages, 2928 KB  
Article
Long-Term Follow-Up of Women with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A 16-Year Longitudinal Study
by Slavica Tomić, Aleksandra Pastornački, Maja Drljača, Jelena Glogovac, Vanja Bošković and Snežana Brkić
Medicina 2026, 62(6), 1114; https://doi.org/10.3390/medicina62061114 - 8 Jun 2026
Viewed by 161
Abstract
Background and Objectives: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disorder characterized by persistent or relapsing fatigue lasting at least six months, not alleviated by rest and not previously present. It is accompanied by post-exertional symptom exacerbation and non-restorative sleep. Fatigue [...] Read more.
Background and Objectives: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disorder characterized by persistent or relapsing fatigue lasting at least six months, not alleviated by rest and not previously present. It is accompanied by post-exertional symptom exacerbation and non-restorative sleep. Fatigue is often disabling and reduces daily activity by more than 50%. This study aimed to evaluate the long-term frequency of somatic and psychiatric disorders in women previously diagnosed with ME/CFS and to describe the long-term clinical course, laboratory findings, and fatigue-related changes during a 16-year follow-up period. Materials and Methods: Sixteen years ago, 40 women diagnosed with ME/CFS according to then-current CDC criteria were enrolled at the Clinic for Infectious Diseases and the Center for Laboratory Medicine, University Clinical Center of Vojvodina. All participants provided informed consent. After 16 years, 20 women agreed to follow-up evaluation. At both time points, participants underwent structured questionnaires, clinical examination, psychological assessment, and comprehensive laboratory testing, including hematological, biochemical, endocrinological, and virological analyses. Fatigue severity was assessed using the FibroFatigue Scale (FFS) and the Multidimensional Assessment of Fatigue (MAF) scale. Results: During follow-up, 15% of participants were diagnosed with rheumatoid arthritis, 10% with cervical or breast cancer, 5% experienced premature myocardial infarction, 5% developed bronchial asthma, and 20% were diagnosed with clinical depression. Progression of ME/CFS was observed in 15%, while 5% reported infertility. Additionally, 15% developed arterial hypertension. Only 15% of participants did not report symptom worsening or new diagnoses. Conclusions: Over the 16-year follow-up, 85% of women with ME/CFS developed significant somatic or psychiatric conditions. These findings suggest that women diagnosed with ME/CFS may experience substantial long-term somatic and psychiatric disease burden, supporting the need for continued clinical monitoring and individualized follow-up. Full article
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22 pages, 549 KB  
Article
Plasma Metabolite Profiles of Exercising American Foxhound Dogs Fed Different Diets
by Sara E. Martini, Maria R. C. de Godoy, Alison N. Beloshapka, Preston R. Buff and Kelly S. Swanson
Metabolites 2026, 16(6), 397; https://doi.org/10.3390/metabo16060397 - 8 Jun 2026
Viewed by 166
Abstract
Background/Objectives: Canine athletes have a higher energy requirement and are more susceptible to nutrient depletion, electrolyte imbalance, and metabolic stress than sedentary pets. The objective of this study was to characterize the plasma metabolome of American Foxhound dogs following a bout of unstructured [...] Read more.
Background/Objectives: Canine athletes have a higher energy requirement and are more susceptible to nutrient depletion, electrolyte imbalance, and metabolic stress than sedentary pets. The objective of this study was to characterize the plasma metabolome of American Foxhound dogs following a bout of unstructured exercise. Methods: Thirty-nine adult American Foxhound dogs (32 intact males, 7 spayed females; age: 6.2 ± 3.1 yr; BW: 36.3 ± 5.3 kg) were allotted to a standard performance diet (CTRL) or NUTRO® Natural Choice® Adult High Endurance Formula (TEST). After 80 d in the study, blood samples were collected prior to (0 h), and 3 h and 25 h post-exercise (average: 17.7 km run over 2–3 h). Plasma samples of the 10 top performers of each treatment group were analyzed for untargeted metabolite profiling. Results: Of the 566 named metabolites identified, >200 and >185 metabolites were impacted (p < 0.05) by exercise and diet, respectively. Principal component analysis indicated distinct clustering by diet. Random forest analysis highlighted several metabolites having a high degree of predictive accuracy based on diet and exercise, with most related to amino acid, lipid, xenobiotic, and cofactor and vitamin metabolism. Relating to exercise, glycolytic end-products and citric acid cycle intermediates were increased at 3 h post-exercise. Similarly, tocopherols and omega-3 polyunsaturated fatty acids were higher in dogs fed TEST than those fed CTRL during recovery, indicating a lower oxidative stress and anti-inflammatory response. Conclusions: Overall, the data suggest a protective effect (lower susceptibility to oxidative stress and muscle fatigue) of feeding a nutrient-fortified diet for dogs undergoing unstructured exercise. Full article
(This article belongs to the Section Animal Metabolism)
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20 pages, 10223 KB  
Article
Predictions of Crack Growth Rates, R-Ratio and Overload Effects Based on Smooth Specimen LCF Data and the Moving Plastic Stress Field Ahead of the Crack Tip
by Steve Williams, Mark Whittaker and Mark Hardy
Materials 2026, 19(11), 2411; https://doi.org/10.3390/ma19112411 - 5 Jun 2026
Viewed by 182
Abstract
The use of the stress intensity factor K to characterize the severity of crack tip stress fields is widespread throughout engineering. The relationship between K and the crack growth rate is then usually represented empirically by a straight line Paris law relationship on [...] Read more.
The use of the stress intensity factor K to characterize the severity of crack tip stress fields is widespread throughout engineering. The relationship between K and the crack growth rate is then usually represented empirically by a straight line Paris law relationship on logarithmic axes. This study develops an analytical relationship between the two by linking crack growth to the accumulation of fatigue damage ahead of the moving crack tip. A stress-based fatigue model was used, with inputs from plastic 2D plane stress FE analyses representing an edge crack by a sharp semi-circular notch. Stress–distance profiles ahead of the crack tip were extracted at the maximum and minimum points of a range of fatigue loading cycles. These were then used with data from smooth specimen LCF tests to predict the build-up of fatigue damage at regularly spaced locations ahead of the crack tip and hence crack growth rates. Full da/dN–ΔK curves were generated for the nickel-based superalloy RR1000 at 20 °C with loading R-ratios of 0, −1 and 0.5. The R = 0 and R = −1 crack growth rate predictions agreed well with experimental data, as did the steeper growth rate slope calculated at R = 0.5. The method was then extended to predict overload behaviour. Full article
(This article belongs to the Special Issue Fatigue Crack Growth in Metallic Materials (3rd Edition))
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17 pages, 2414 KB  
Article
Experimental and Analytical Investigation of Transverse Bending Resistance in Steel Threaded Joints
by Maurizio Arena, Vincenzo Raiola, Francesco Spinaci, Mario Miano, Martina Castaldo and Francesco Bocchetto
Appl. Sci. 2026, 16(11), 5637; https://doi.org/10.3390/app16115637 - 4 Jun 2026
Viewed by 124
Abstract
Rod ends are critical structural components primarily designed to sustain axial loads in mechanical and aeronautical assemblies. However, operational conditions may involve transverse loading, which induces significant bending stresses concentrated in the threaded shank region. This research presents an experimental investigation aimed at [...] Read more.
Rod ends are critical structural components primarily designed to sustain axial loads in mechanical and aeronautical assemblies. However, operational conditions may involve transverse loading, which induces significant bending stresses concentrated in the threaded shank region. This research presents an experimental investigation aimed at characterizing the elastoplastic bending behavior of the threaded portion of rod ends subjected to such off-axis loads. Specimens manufactured from precipitation-hardened stainless steel 17-4 PH were tested under both displacement and force control strategies. Each specimen was subjected to incremental loading until failure to determine the elastic limit, yield point, ultimate bending strength and fracture mode. The experimental results enabled a preliminary assessment of the static resistance of the threaded region; furthermore, a comparison with analytical formulations and empirical estimation methods available in the literature revealed promising agreement. These findings highlight the importance of accounting for non-axial loading in the design of threaded joints for critical applications. This study establishes a baseline for broader experimental campaigns aimed at validating these results and exploring fatigue behavior under cyclic transverse loads. Full article
(This article belongs to the Special Issue Steel Structures: Modelling, Experiments and Applications)
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16 pages, 1451 KB  
Article
Functional Thresholds Derived from Dynamometry and 6-Minute Walk Test with Morphofunctional Assessment to Guide Individualized Exercise Prescription in Cardiac Rehabilitation
by María del Mar Amaya-Campos, Ramón Zafra Jiménez, Rocío Fernández-Jiménez, Isabel M. Vegas-Aguilar, María García-Olivares, Mónica Diaz-Cordovés Rego, Yolanda Ruiz Molina, Adela María Gómez González, Angel Montiel Trujillo, Francisco Tinahones-Madueño, José Manuel García-Almeida and Lucía Jiménez Laguna
J. Clin. Med. 2026, 15(11), 4336; https://doi.org/10.3390/jcm15114336 - 3 Jun 2026
Viewed by 222
Abstract
Background/Objectives: To evaluate the associations and concurrent validity between baseline functional and morphofunctional assessments in patients with cardiovascular disease participating in a Phase II cardiac rehabilitation program, as a basis for informing individualized exercise prescription. Methods: We conducted an observational retrospective [...] Read more.
Background/Objectives: To evaluate the associations and concurrent validity between baseline functional and morphofunctional assessments in patients with cardiovascular disease participating in a Phase II cardiac rehabilitation program, as a basis for informing individualized exercise prescription. Methods: We conducted an observational retrospective cross-sectional study of patients enrolled in a Phase II outpatient cardiac rehabilitation program (January 2021–December 2023, Málaga). Functional assessments included handgrip strength (HGS), isometric biceps and quadriceps dynamometry, and direct assessment of 20-repetition maximum (20RM) through dynamic resistance exercises using external loads (defined as the maximum load allowing approximately 20 repetitions to near muscular fatigue). Aerobic capacity was evaluated using the 6-min walk test (6 MWT) and a modified Bruce exercise stress test with estimated METs. Morphofunctional assessment included vector bioimpedance analysis (phase angle [PhA], fat-free mass [FFM], body cell mass [BCM]) and rectus femoris ultrasound (cross-sectional area [RF-CSA] and contracted diameter [RF-CON]). Correlation and linear regression analyses were performed. Results: The sample included 223 participants (78.0% male; age 57.7 ± 8.6 years). HGSmax correlated strongly with 20RM biceps (r = 0.89) and moderately with quadriceps (r = 0.72). 6 MWT distance and speed correlated with ergometry-derived METs (r = 0.38–0.40; p < 0.001), whereas Borg ratings correlated inversely with METs and exercise time (r = −0.32 to −0.34; p < 0.001). PhA, BCM, FFM, and rectus femoris ultrasound measures correlated with both strength and aerobic outcomes (ρ ≈ 0.33–0.50; all p < 0.001). In regression analyses, HGSmax was the main predictor of 20RM biceps (R2 = 0.792) and showed moderate predictive capacity for quadriceps performance (R2 = 0.521). The MET model demonstrated limited explanatory capacity (R2 = 0.288). Conclusions: The integration of simple, accessible, and reproducible tools such as HGS and the 6 MWT with morphofunctional parameters may provide a pragmatic approach to support individualized exercise prescription in cardiac rehabilitation. While stronger associations were observed for upper-limb resistance performance, the predictive capacity for lower-limb strength and aerobic exercise intensity was more moderate and should be interpreted cautiously. These findings support the potential clinical utility of combining functional and morphofunctional assessments in routine cardiac rehabilitation practice. Full article
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Article
Baseline Functional Performance Predicts Better Long-Term Self-Reported Physical Function After Auto-HSCT
by Lindsey J. Anderson, Lily Okamura, Nina Dhunjishah, Roshni Gowrisankar, Jennifer Song, Thomas R. Chauncey and Jose M. Garcia
J. Clin. Med. 2026, 15(11), 4318; https://doi.org/10.3390/jcm15114318 - 3 Jun 2026
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Abstract
Background/Objectives: Determination of baseline predictors of longer-term quality of life (QOL) after autologous hematopoietic stem cell transplantation (Auto-HSCT) may identify patients with the greatest supportive care needs. We hypothesized that baseline older age, weight loss, and worse functional performance would negatively predict [...] Read more.
Background/Objectives: Determination of baseline predictors of longer-term quality of life (QOL) after autologous hematopoietic stem cell transplantation (Auto-HSCT) may identify patients with the greatest supportive care needs. We hypothesized that baseline older age, weight loss, and worse functional performance would negatively predict QOL over two years post-HSCT. Methods: Physical function, body composition, and QOL were assessed before (PRE) and one month (1MO) after Auto-HSCT in U.S. Veterans (N = 23). QOL and survival were also assessed approximately every six months for two years after Auto-HSCT (5MO, 1YR, 1.5YR, and 2YR). Changes over time were tested via Generalized Estimating Equation regression analyses (p < 0.05 = significant). The impact of PRE variables on QOL at each follow-up was tested via Spearman’s correlations (p < 0.01 = significant). Results: Relative to PRE, depression and anxiety significantly improved (p ≤ 0.039) at 1MO while fatigue and vitality significantly worsened (p ≤ 0.024) 1MO to 5MO post-HSCT. Vitality, depression, and anxiety returned to PRE levels thereafter, while fatigue trajectory varied depending on the survey used. Bone-Marrow-Transplant-related QOL significantly improved at 5MO (p = 0.014) while self-reported function (p ≤ 0.021) and physical activity (p ≤ 0.045) significantly improved 1-2YR post-HSCT. Greater PRE 30 s chair stand test performance consistently correlated with better self-reported function 1-2YR (r = 0.76–0.91, p ≤ 0.007) post-HSCT. Greater PRE 6 min walk test performance consistently correlated with better symptom burden 1-2YR (r = 0.71–0.81, p ≤ 0.01) post-HSCT. Conclusions: In support of our hypothesis, baseline functional performance was associated with QOL during two years of recovery after Auto-HSCT; older age and recent weight loss at baseline only predicted worse baseline QOL. Our data indicates that evaluation of the 30 s chair stand and 6 min walk tests as rehabilitation targets and/or predictors of QOL, fitness, or mortality after Auto-HSCT are warranted. Larger, controlled studies are needed to confirm the findings from this exploratory analysis. Full article
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