Search Results (97)

Antimicrobial resistance (AMR) is a major global concern in both human and veterinary medicine. Among antimicrobial resistance (AMR) bacteria, Extended-Spectrum Beta-Lactamases (ESBLs) pose a serious health risk because infections can be difficult to treat. These Gram-negative bacteria can be frequently found in poultry and in Italy, where such protein production is established. ESBL-producing Escherichia coli, Salmonella and Klebsiella in chicken and turkey may pose a significant public health risk due to potential transmission between poultry and humans. This review aims to assess the prevalence of ESBL-producing E. coli, Salmonella and Klebsiella phenotypically and genotypically in Italian poultry, identifying the most common genes, detection methods and potential information gaps. An initial pool of 1462 studies found in scientific databases (Web of Sciences, PubMed, etc.) was screened and 29 were identified as eligible for our review. Of these studies, 79.3% investigated both phenotypic and genotypic ESBL expression while ${bla}_{CTX-M}$, ${bla}_{TEM}$ and ${bla}_{SHV}$ were considered as targeted gene families. Large differences in prevalence were reported (0–100%). The ${bla}_{CTX-M-1}$ and ${bla}_{TEM-1}$ genes were the most prevalent in Italian territory. ESBL-producing E. coli, Salmonella and Klebsiella were frequently detected in farms and slaughterhouses, posing a potential threat to humans through contact (direct and indirect) with birds through handling, inhalation of infected dust, drinking contaminated water, ingestion of meat and meat products and the environment. Considering the frequent occurrence of ESBL-producing bacteria in Italian poultry, it is advisable to further improve biosecurity and to introduce more systematic surveillance. Additionally, the focus should be on the wild birds as they are ESBL carriers. Full article

In the present study, liquid chromatography–quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) was employed to analyze chlorinated paraffin (CP) homolog distributions and concentrations in household dust from South China and the Midwestern United States. The median levels of short-, medium-, and long-chain CPs (∑SCCPs, ∑MCCPs, ∑LCCPs) in South China were quantified as 23.1, 36.2, and 32.8 μg/g, respectively. Comparatively, the corresponding values in the Midwestern U.S. samples were 9.4, 39.5, and 15.4 μg/g, respectively. Notably, ∑LCCP concentrations in South China significantly exceeded those in the U.S. (p < 0.05), while no difference was found for ∑SCCPs and ∑MCCPs. Additionally, very short-chain CPs (C_≤9) were detected in 13% of samples across both regions. The distribution of CP homologues in the dust samples from the two regions was similar, with C₁₃, C₁₄, and C₁₈ groups as the predominant carbon homologue and Cl_7-8, Cl_7-9, and Cl_9-10 as the predominant chlorine homologue of SCCPs, MCCPs, and LCCPs, respectively. Risk assessment indicated dust ingestion-derived CP intakes for adults and toddlers were 2–5 orders of magnitude below reference doses. However, given other exposure pathways and the combined effects of CP monomers, the potential health risks from exposure via dust should not be underestimated. Full article

Festivals are significant markers of cultural heritage and community traditions. Nevertheless, every year, significant increases in pollution levels are recorded during celebratory events, due to the overuse of firecrackers. This study evaluated gaseous and particulate matter (PM) concentrations using a gas and particulate sampler, alongside noise levels measured by a sound level meter, during the pre-to-post-Diwali period of 2023 and 2024 in Malda, India, and PM concentrations in Warsaw, Poland in 2024, using a DustAir dust meter. The results indicated that during Diwali, the concentrations of PM_2.5 and PM₁ exceeded the standard set by the World Health Organization, while gaseous pollutants remained within acceptable limits. Since no standards set for PM₁ exist, PM_2.5 criteria were utilized as a benchmark. Additionally, on New Year’s Eve in Warsaw, concentrations of PM₁₀, PM_2.5, and PM₁ surpassed the standard around midnight, while gaseous pollutants remained within the standard range. An elemental analysis revealed 13 elements in Diwali PM samples, with toxic metals like arsenic and cadmium more prevalent in PM₁. The risk of carcinogenic and non-carcinogenic effects through ingestion was higher for children compared to adults. The findings of this study could potentially raise awareness among researchers and policymakers, prompting them to develop sustainable substitutes for firecrackers and sparklers. Full article

Rapid urbanization and associated transportation play a crucial role in the distribution of heavy metals in road dust, leading to serious environmental and health concerns. This study explored the concentration and spatial variability of metals, including cadmium (Cd), copper (Cu), lead (Pb), and zinc (Zn), in road dust across six urban zones in Guangdong Province (parks, educational, residential, commercial, traffic, and industrial areas). The study also evaluated the bioavailability of these metals to determine their carcinogenic and non-carcinogenic health impacts. The findings revealed significant variations in metal levels, with commercial zones having the highest concentrations of Zn 1316.1 ± 381.6 mg/kg), Cu (426.1 ± 136.7 mg/kg), and Cd (1.29 ± 0.08 mg/kg) due to the deposition of traffic emissions. The bioaccessibility of Pb, Zn, and Cd was found to be higher in the gastric phase, suggesting increased absorption potential when ingested. Children were at a significantly higher non-carcinogenic risk compared to adults, facing more than double the exposure. While the carcinogenic risk from Pb was low but notable, Cd presented minimal risk. These results highlight the need for targeted interventions, including stricter emission regulations and public health strategies, to mitigate the risks of heavy metal exposure in urban areas. Full article

Based on GJB 242A, a detailed experimental procedure for the sand and dust ingestion of a turboshaft engine was established. A specific type of turboshaft engine was used to conduct 54 h full-engine sand and dust ingestion experiments. This research studied the impact of sand and dust ingestion on the engine’s common operating line, power loss, specific fuel consumption, and gas turbine exhaust temperature, among other performance parameters. The experimental results indicate that under the same equivalent power conditions, the impact of short-term sand and dust ingestion on the engine’s common operating line is minimal; as the sand and dust ingestion time increases, the equivalent airflow decreases significantly, causing the engine’s common operating line to shift upward and the gas turbine exhaust temperature to rise, with the maximum increase reaching 27.9 °C. However, the impact of sand and dust ingestion on the gas turbine exhaust temperature at high power levels is relatively small. After completing the sand and dust ingestion test, the engine’s power loss at maximum continuous operation was approximately 11.33%, and the specific fuel consumption increased by about 6.05%. The power loss does not meet the requirement of being less than 10% as stipulated in GJB 242A. Based on the engine disassembly inspection results, subsequent improvement suggestions were proposed. The findings of this paper can provide a scientific and rational basis and reference for the sand and dust resistance design and sand ingestion testing of similar aero-engines. Full article

This comprehensive review reports on concentrations, sources, emissions, and potential health effects from Semi-Volatile Organic Compounds (SVOCs) identified in the internal home environment in European residences. A total of 84 studies were identified, and concentrations were collated for inhalation exposure from dust, air and aerosol. A total of 298 individual SVOCs were identified and 67 compounds belonging to eight chemical classes: phthalates, flame retardants, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), per- and polyfluorinated alkyl substances (PFAS), biocides, bisphenols and musks were prioritised. Phthalates are the most abundant SVOCs with DEHP being the most abundant in both the dust and aerosol phases (WAGMs 426.4 μg g⁻¹ and 52.2 ng m⁻³, respectively) followed by DBP for dust (WAGMs are 95.9 μg g⁻¹). In the air, the most abundant SVOCs are DiBP (284.1 ng m⁻³), DBP (179.5 ng m⁻³), DEHP (106.2 ng m⁻³) and DMP (27.79 ng m⁻³). Chemicals from all SVOC categories are emitted from building and construction materials, furnishings and consumer products, especially phthalates. Both legacy chemicals and their alternatives were detected. Complexities of reporting on SVOCs included differing sampling methodologies, multiple standards in their definition, lack of industry data, and toxicological data focused primarily on ingestion not inhalation exposures. Further research is recommended to develop the evidence base for potential health effects including via inhalation, reporting of emission rates and undertaking future monitoring studies. Full article

Graphene and its derivatives (GDs) have been applied in many fields, like photocatalysts, sensors, and biomedical delivery, due to its excellent physicochemical properties. However, the widespread use of GDs has significantly increased human exposure to these materials. Some health risks of exposure to GDs have been identified, including organ fibrosis, inflammation, DNA damage, etc. Given that graphene is a novel concern, we especially emphasized the various exposure pathways and potential health risks of exposure to GDs. People get exposed to GDs mainly through inhalation, ingestion, dermal contact, etc. GDs could transfer to the circular system of people and accumulate in blood, cells, and major organs. GDs exposure could induce organ and cell inflammatory responses and damage, such as disrupted kidney function, declined cell vitality, cytotoxicity, etc. These changes at the organ and cell levels might lead to adverse tangible influences on people, like decreased locomotor activity, the accelerated aging process, and even abnormal offspring development. We also summarized the characterization and detection methods of GDs. In addition, we compared the studies of exposure to dust and GDs in the aspects of health risks and study methods. This review could offer a comprehensive summary related to GDs and provide helpful references for further graphene-related studies. Full article

The aim of this study was to evaluate the possible contamination of urban dust in the schoolyards of 27 schools in an urban area of the city of Murcia (SE Spain). The color and degree of magnetism, as well as the heavy metal content (Cd, Cu, Cr, Ni, Pb, and Zn), were determined to establish the absence or the degree of contamination, if present, using environmental and health indices. It was established that the concentrations of heavy metals in the dust samples followed the order Zn (454 mg kg⁻¹) > Cu (77 mg kg⁻¹) > Cr (68 mg kg⁻¹) > Pb (56 mg kg⁻¹) > Ni (19 mg kg⁻¹) > Cd (0.4 mg kg⁻¹). Dark-colored dust showed the highest concentrations of contaminants associated with medium or high magnetism. An analysis of the magnetic and non-magnetic fractions indicated the highest concentrations of all heavy metals in the magnetic fraction. According to the geoenvironmental indices used, the ecological risk in these schoolyards is moderate overall. Based on the health indices, ingestion is the main route of entry of dust particles into the body, which poses the main health risk for adults and children for all heavy metals. Regarding the hazard index (HI) for all elements and the cancer risk (CR) for children and adults, the results indicate that there is no health risk. Full article

Heavy metals in road dusts can directly pose significant health risks through ingestion, inhalation, and dermal contact. This study investigated the pollution, distribution, and health effect of heavy metals in street dust from industrial, capital city, and peri-urban areas of Bangladesh. Inductively coupled plasma mass spectrometry (ICP-MS) examined eight hazardous heavy metals such as Zn, Cu, Pb, Ni, Mn, Cr, Cd, and Co. Results revealed that industrial areas showed the highest metal concentrations, following the order Mn > Zn > Cr > Pb > Ni > Co > Cd, with an average level of 444.35, 299.25, 238.31, 54.22, 52.78, 45.66, and 2.73 mg/kg, respectively, for fine particles (≤20 μm). Conversely, multivariate statistical analyses were conducted to assess pollution levels and sources. Anthropogenic activities like traffic emissions, construction, and industrial processing were the main pollution sources. A pollution load index revealed that industrial areas had significantly higher pollution (PLI of 2.45), while the capital city and peri-urban areas experienced moderate pollution (PLI of 1.54 and 1.59). Hazard index values were below the safety level of 1, but health risk evaluations revealed increased non-carcinogenic risks for children, especially from Cr, Ni, Cd, and Pb where Cr poses the highest cancer risk via inhalation, with values reaching 1.13 × 10⁻⁴–5.96 × 10⁻⁴ falling within the threshold level (10⁻⁴ to 10⁻⁶). These results underline the need for continuous environmental monitoring and pollution control in order to lower health hazards. Full article

Fifty-one street dust samples were systematically collected from the urban core of Zhengzhou, China, and analyzed for potentially toxic metals. The concentrations of vanadium (V), manganese (Mn), copper (Cu), zinc (Zn), arsenic (As), lead (Pb), and nickel (Ni) in the samples surpassed the background values of the local soil, indicating a notable potential for contamination. Spatially, the traffic area was the most polluted with a total heavy metal concentration of Cu, Zn, As, Pb, and Ni, while the pollution levels were lower in the culture and education area and commercial area with total concentrations of V and Mn. Seasonal variations were discerned in the concentrations of heavy metals, with V, Cu, Zn, and As exhibiting heightened levels during the fall and winter, while Mn, Ni, and Pb reached peaks in the spring season. Zn exhibited the highest mean geo-accumulation index (I_geo) value at 2.247, followed by Cu at 2.019, Pb at 0.961, As at 0.590, Ni at 0.126, Mn at −0.178, and V at −0.359. The potential ecological risk index (RI) in the traffic-intensive area markedly exceeded other functional areas. Health risk assessments showed that children were more vulnerable to heavy metal exposure than adults, particularly through the ingestion pathway. Correlation analysis, principal component analysis (PCA), and cluster analysis (CA) were applied in conjunction with the spatial–temporal concentration patterns across various functional areas to ascertain the plausible sources of heavy metal pollutants. The results indicated that heavy metals in the urban street dust of Zhengzhou were multifaceted, stemming from natural processes and diverse anthropogenic activities such as coal burning, industrial emissions, traffic, and construction operations. Full article

Studies on tollbooth workers involving the concentration of metal(loid)s in highway dust are scarce. We aimed to assess the levels of metal(loid)s in soils and washed and unwashed leaves of Brachiaria decumbens on roadsides. Dust deposition and heavy metal content in the leaves are used to estimate the exposure of tollbooth workers to oral, inhalation, and dermal ingestion of metals in highway dust. The concentrations of aluminum (Al), arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), iron (Fe), nickel (Ni), zinc (Zn), and lead (Pb) in washed and unwashed soil and leaves were analyzed using inductively coupled plasma optical emission spectroscopy. The results showed that soils along highways had a high concentration of heavy metals. Concentrations of Cd, Cu, Cr, Ni, and Pb near the roundabout and tollbooth are higher than the concentrations at the points between them. The highest transfer factor values were determined for aluminum. In the case of the non-carcinogenic effect, the hazard index (HI < 1) of tollbooth workers due to oral exposure to street dust containing metal(loid)s is higher than dermal contact and inhalation. The Incremental Lifetime Cancer Risk showed a high potential carcinogenic risk for As and Cd. Full article

The global proliferation of synthetic microfiber waste has emerged as a pressing environmental concern due to its widespread distribution in both aquatic and terrestrial ecosystems. Primary sources of synthetic microfibers include laundering of synthetic textiles, manufacturing, and plastic breakdown, with transport via wastewater, runoff, atmospheric deposition, and animal ingestion. This review highlights the sources of microfiber formation and accumulation, ranging from freshwater lakes and rivers to deep-sea sediments. The presence of microfibers in agricultural soils, urban dust, and even remote locations indicates atmospheric transportation and diverse accumulation patterns. Additionally, this review discusses the transportation of microfibers through various pathways and elaborates on various treatment technologies for microfiber removal and reduction. The potential human health impacts and mitigation solutions are also highlighted. Overall, this review aims to provide comprehensive knowledge of the sources, transport mechanisms, and accumulation patterns of synthetic microfibers, emphasizing their multifaceted environmental impact and the need for further research to develop effective solutions. Full article

Heavy metals in road dust pose potential health risks to humans, while oral bioaccessibility and sources are all important factors influencing this health risk. However, few prior studies have combined them for health risk analysis. In this study, road dust samples were collected from different geographical locations of Jinan (west area, WA; central area, CA; and east area, EA) to analyze the source-specific and bioaccessibility-based health risks of heavy metals. The mean concentrations of heavy metals in the three areas were CA > EA > WA, with Cd, Cu, Mn, Pb, and Zn exceeding their corresponding background values. A source analysis using a Positive Matrix Factorization (PMF) model showed that traffic emissions were the main source of heavy metals in the WA and CA, while industrial activities were the main source in the EA. The mean bioaccessibility of heavy metals extracted using the Solubility Bioaccessibility Research Consortium (SBRC) method followed the order of Cd (75.5%) > Zn (42.2%) > Mn (42.1%) > Pb (42.0%) > Cu (32.9%) > As (23.6%) > Ni (20.1%) > V (16.8%) > Cr (13.3%). According to the combined source analysis, traffic was the primary risk factor in the WA (54.5 and 58.3% of NCR and CR, respectively) and CA (61.8 and 51.2%), with solid waste being the main risk factor in the EA (41.9 and 51.3%). In oral bioaccessibility testing, lower non-carcinogenic (<1.0) and carcinogenic risks (<1 × 10⁻⁶) of heavy metals were observed than those based on the total metal content. More importantly, As (43.4%) was replaced by V (29.7%) as the main contributor to NCR. Source-specific and bioaccessibility-based health risk assessments can accurately identify priority pollutants and heavy metals in urban road dust that need to be controlled. This provides more effective and accurate urban environmental risk management recommendations for sustainable urban development and population health. Full article

Phthalate acid esters (PAEs) are one of the most widely used plasticizers globally, extensively employed in various decoration materials. However, studies on the impact of these materials on indoor environmental PAE pollution and their effects on human health are limited. In this study, forty dust samples were collected from four types of stores specializing in decoration materials (flooring, furniture boards, wall coverings, and household articles). The levels, sources, exposure doses, and potential health risks of PAEs in dust from decoration material stores were assessed. The total concentrations of Σ₉PAE (the sum of nine PAEs) in dust from all decoration-material stores ranged from 46,100 ng/g to 695,000 ng/g, with a median concentration of 146,000 ng/g. DMP, DEP, DBP, and DEHP were identified as the predominant components. Among all stores, furniture board stores exhibited the highest Σ₉PAE (159,000 ng/g, median value), while flooring stores exhibited the lowest (95,300 ng/g). Principal component analysis (PCA) showed that decoration materials are important sources of PAEs in the indoor environment. The estimated daily intakes of PAEs through non-dietary dust ingestion and dermal-absorption pathways among staff in various decoration-material stores were 60.0 and 0.470 ng/kg-bw/day (flooring stores), 113 and 0.780 ng/kg-bw/day (furniture board stores), 102 and 0.510 ng/kg-bw/day (wall covering stores), and 114 and 0.710 ng/kg-bw/day (household article stores). Particularly, staff in wall-covering and furniture-board stores exhibited relatively higher exposure doses of DEHP. Risk assessment indicated that although certain PAEs posed potential health risks, the exposure levels for staff in decoration material stores were within acceptable limits. However, staff in wall covering stores exhibited relatively higher risks, necessitating targeted risk-management strategies. This study provides new insights into understanding the risk associated with PAEs in indoor environments. Full article

Bisphenol S (BPS), an environmental endocrine disruptor, has been identified in global environmental matrices. Nevertheless, limited studies have investigated the presence of chlorinated analogues of BPS (Clx-BPSs) with potential estrogenic activities in environmental matrices. In this study, the occurrence of BPS and five types of Clx-BPSs was characterized in indoor dust (n = 178) from Hangzhou City. BPS was measurable in 94% of indoor dust samples, with an average level of 0.63 μg/g (<LD–2.4 μg/g). Among the detected Clx-BPSs homologues, Cl₁-BPS (2-chloro-4-(4-hydroxyphenyl)sulfonylphenol; detection frequency 70%), Cl₂-BPS-2 (2-chloro-4-(3-chloro-4-hydroxyphenyl)sulfonylphenol; 65%), and Cl₂-BPS-1 (2,6-dichloro-4-(4-hydroxyphenyl)sulfonylphenol; 61%) were among the frequently detected Clx-BPSs. Cl₁-BPS was the most abundant analyte, with an average of 0.048 μg/g (<LD—0.24 μg/g), followed by Cl₂-BPS-1 (0.035 μg/g, <LD—0.14 μg/g), and Cl₂-BPS-2 (0.031 μg/g, <LD—0.13 μg/g). Significant correlations in indoor dust concentrations were observed between BPS and Cl₁-BPS (p < 0.01), as well as between BPS and Cl₂-BPS-1 (p < 0.01). Moreover, an estimation was made for the total daily intake of Clx-BPSs via the ingestion of indoor dust by infants, children, and adults. This study presents the first evidence of the existence of Clx-BPSs in indoor dust, concurrently highlighting the necessity to address their potential human exposure risks. Full article