Search Results (3,687)

Precision Livestock Farming (PLF) tools are increasingly used in dairy production, but their success depends on farmers’ perceptions, needs and investment capacity. This study explores the current use of digital technologies, satisfaction levels and future expectations among Italian dairy farmers. An online questionnaire with 19 questions collected 53 complete responses between May and November 2025. Most of the farms were free-stall Holstein dairy farms located in the Po Valley and managed by relatively young and well-educated farmers, many of whom had a background in animal production. The adoption of PLF tools was widespread: management software (73.6%), automated total mixed ration (TMR) preparation (66.0%), heat stress mitigation systems (62.3%) and collar sensors (52.8%) were the most adopted technologies. Satisfaction with current tools was high, although installation costs and poor system integration were consistently identified as major constraints. Farmers expressed clear priorities for future devices, particularly early diagnosis of health problems, calving, heat, lameness, and feeding and rumination functions. The results suggest that PLF in Italian dairy systems is moving from the adoption phase to that of consolidation. However, improvements in interoperability, affordability and farmer-centred design remain essential to support a wider and more equitable spread of the technology across the sector. Full article

Skeleton-based action recognition is a critical technology for intelligent sports analysis. Although the human skeletal structure exhibits inherent bilateral symmetry, sensor noise on resource-constrained edge devices frequently induces geometric distortion and topological asymmetry. Consequently, achieving a balance between high accuracy and real-time performance remains a significant challenge. To this end, we propose EMS-GCN, an Efficient Multi-scale Shift Graph Convolutional Network that integrates geometric priors. Specifically, we design a Gaussian kernel-driven topology refinement module to mitigate structural noise inherent in sensor data. By leveraging geometric symmetry and Gaussian distances among nodes, this module dynamically constrains graph topology learning, thereby effectively rectifying the structural asymmetry and ambiguity induced by noise. Furthermore, we construct a Multi-scale Shift Linear Attention (MSLA) module to replace computationally intensive temporal convolutions. Leveraging temporal shift invariance, this module captures multi-scale contexts via parameter-free shift operations. Furthermore, we introduce a linear temporal attention mechanism to model global temporal dependencies with linear complexity, effectively resolving the information asymmetry inherent in long-range interactions. Finally, EMS-GCN incorporates a dual-branch attention structure to adaptively calibrate feature responses. Extensive experiments demonstrate that our model maintains high recognition accuracy with only 0.56M parameters, representing a reduction of over 60% compared to mainstream baselines. These results validate the efficacy of leveraging geometric and temporal symmetries to enhance real-time sports analysis. Full article

Hot-filament chemical vapor deposition (HFCVD) facilitates the realization of industrial mass production owing to its simple synthesis device, facile control of process conditions, and low preparation cost. Reactive pressure is one of the deposition parameters that exert a profound influence on the growth of HFCVD diamond films on polycrystalline diamond (PCD) substrates, primarily affecting the growth rate and grain size of the deposited diamond coating. A univariate experimental approach was employed to investigate the effects of reactive pressure (2 kPa, 3 kPa, 4 kPa, 5 kPa) on the properties of as-deposited diamond films. The results show that with the increase in reactive pressure, the growth rate increased first and then decreased, peaking at 5.366 μm/h at 3 kPa. The fractal dimension and grain size follow a similar variation trend, both decreasing first and then increasing. The grain size drops to 15.8 nm when the reactive pressure is 3 kPa, at which point the adhesive strength of the film is maximized. This phenomenon can be attributed to the fact that excessively low reactive pressure extends the mean free path of particles and active species, endowing them with higher kinetic energy and reducing collision-induced energy loss. This in turn significantly promotes diamond nucleation, secondary nucleation and grain refinement, thus facilitating the growth of nanocrystalline diamond. In contrast, an excessively high pressure yields the opposite effect, inhibiting nucleation and promoting grain coarsening. Full article

Real-world evidence for wearable noninvasive glucose monitoring (NIGM) remains limited. To evaluate the functional equivalence of a wearable NIGM device and explore its utility for T2DM and prediabetes screening. In this multicenter study, 12-h daytime glucose profiles obtained by a flexible reverse iontophoresis-based electrochemical sensor were compared with capillary glucose using functional equivalence. Subgroup analyses were conducted. Screening models of T2DM and prediabetes were developed using elastic net and Logistic regression. A total of 135 participants (mean age 35.3 years; 60.0% female) were included, and no serious device-related adverse events were reported. Compared to the capillary measurements, functional equivalence was confirmed (T = −6.537 < threshold = −2.081) in the general population but not in older adults or T2DM patients. The T2DM noninvasive screening model demonstrated discrimination and reclassification performance comparable to those of the capillary-based model (AUC: 0.906 vs. 0.850, NRI: 0.044, IDI: −0.078, p > 0.05). Functional principal component scores facilitated the identification of prediabetes (AUC = 0.760). The device demonstrated acceptable accuracy and functional equivalence with reference methods. Its capability to detect T2DM and early glycemic anomalies supports its feasibility as a wearable, interpretative adjunct tool for large-scale screening in free-living populations. Full article

Polymer films and coatings play an increasingly critical role in extending material functionality across industrial, biomedical, and environmental applications. Recent advances in surface engineering have enabled precise control of interfacial properties, leading to enhanced durability, cleanliness, and protection. This review summarizes state-of-the-art strategies for modifying polymer surfaces, with an emphasis on plasma-based surface modification and plasma-induced polymerization as versatile, solvent-free methods for tailoring wettability, chemical functionality, and adhesion. Furthermore, it examines emerging classes of self-cleaning and self-sterilizing coatings that leverage photocatalytic, hydrophobic, or antimicrobial mechanisms to mitigate contamination, biofouling, and pathogen transmission. Additionally, developments in high-performance barrier films designed to protect food products and electronic devices through improved resistance to gases, moisture, and chemical agents are highlighted. By integrating insights from materials chemistry, surface physics, and nanostructured coating design, this review provides a comprehensive overview of current achievements and future directions in functional polymer films and coatings aimed at anti-pollution, antibacterial, and anti-corrosion performance. Full article

The 795 nm wavelength corresponds to the D1 transition of rubidium atoms and is widely used in atomic optical pumping, atomic clocks, magnetometers, and precision spectroscopy. For compact free-space collimation, beam shaping, and efficient fiber coupling, edge-emitting semiconductor lasers with reduced fast-axis (vertical) divergence are highly desirable, yet low-divergence designs at 795 nm remain limited. Here, we propose and demonstrate low-divergence photonic-crystal epitaxy (LD–PC) for 795 nm edge-emitting lasers. By engineering a periodic n-side photonic-crystal stack to place the fundamental vertical mode near the photonic band edge, the vertical mode is expanded while maintaining effective modal discrimination. Narrow-ridge Fabry–Pérot lasers based on GaAsP/AlGaAs single-quantum-well epitaxy were fabricated and characterized. The optimized LD–PC device (3 μm ridge width, 1 mm cavity length) delivers 227 mW at 200 mA with a threshold current of 23 mA, a slope efficiency of 1.28 W/A, and a peak wall-plug efficiency of 55% under continuous-wave operation at 25 °C. The measured far-field divergences (FWHMs) are 7.16° and 18.83° in the lateral and vertical directions, respectively, corresponding to a reduction in the vertical divergence from >40° in the reference structure to <20° with LD–PC. These results validate photonic-crystal epitaxy as an effective route toward compact, high-performance, low-divergence 795 nm semiconductor laser sources for rubidium-based atomic systems. Full article

Biosensors based on electrolyte-gated organic field-effect transistors (EGOFETs) have attracted considerable attention due to their advantages, including low cost, inherent signal amplification, and low-voltage operation. A critical step influencing sensing performance is the integration of specific receptors onto the device surface. Among various strategies, the covalent immobilization of biorecognition elements onto gold surfaces via thiol chemistry is one of the most widely used approaches. In this study, we report the optimization of a mixed self-assembled monolayer (SAM) composed of 11-mercaptoundecanoic acid (11-MUA) and 3-mercaptopropionic acid (3-MPA) for label-free detection of human IgG using EGOFETs. The quality of the SAM was systematically modulated by varying the total concentration from 10 to 400 mM and characterized using X-ray Photoelectron Spectroscopy (XPS), Electrochemical Impedance Spectroscopy (EIS), Cyclic Voltammetry (CV), and Atomic Force Microscopy (AFM). The results revealed that a concentration of 50 mM yielded a densely packed and well-ordered monolayer. After covalent immobilization of anti-IgG antibodies via 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) chemistry and subsequent blocking with ethanolamine and bovine serum albumin (BSA), the functionalized gate electrodes were integrated into poly(3-hexylthiophene) (P3HT)-based EGOFETs. Electrical measurements demonstrated that EGOFET biosensors functionalized with the 50 mM SAM achieved optimal sensing performance. The devices exhibited a highly linear response (R² = 0.998) over a wide concentration range from 1 fM to 10 nM, with a LOD of 2.82 fM, and showed excellent selectivity against non-target immunoglobulins A and M (IgA and IgM). This SAM concentration optimization strategy provides a versatile approach for engineering high-performance EGOFET biosensors, with potential applicability to a broad range of disease biomarkers. Full article

Animal welfare in farmed animals is increasingly being identified as an integral part of ethical meat production; yet in most developing nations, including Ghana, little attention is being paid to this area of interest. The demand for chicken meat and egg products in Ghana has also increased because of rapid urbanisation and development; hence, public perception of poultry welfare is paramount in policy formulation and development in Ghana. This study investigates public perception of poultry welfare in Ghana, particularly laying hen farming. The study used a cross-sectional study and surveyed 1275 respondents aged 17 and older in Accra, Kumasi, and Tamale by collecting data in-person, and the questionnaire was administered using tablets or mobile devices. The study found that 69.1% of respondents poorly perceived farmed animal welfare, while 30.9% positively perceived farmed animal welfare in Ghana. There was a significant difference in perception levels among respondents in Accra and Kumasi, and those in Tamale, where respondents in Tamale indicated a slightly positive perception compared to those in Accra and Kumasi. Furthermore, 53.7% of respondents supported state intervention in farmed animal welfare, while 52.0% showed reluctance to pay a premium price for cage-free and free-range egg production in Ghana. Full article

The implementation of stringent regulatory policies for foodborne pathogens necessitates ultra-sensitive analytical methods. Digital detection, characterized by absolute quantification and tolerance to complex matrices, serves as a robust approach for food safety monitoring. This review summarizes recent advances in digital detection for foodborne pathogens, including nucleic acid amplification-based platforms such as droplet digital PCR and digital isothermal amplification, as well as emerging preamplification-free approaches based on enzyme-mediated signal conversion, functional nanomaterials, and microfluidic devices. We also profile the applications of digital detection technologies for achieving highly specific and accurate detection of foodborne pathogens and discuss their capabilities in viable bacteria quantification, antimicrobial resistance analysis, and multiplex detection. We finally discuss emerging trends, including partition-free digital detection and artificial intelligence-assisted analysis. These advances are expected to promote the development of intelligent and data-driven food safety surveillance strategies. Full article

Sleep quality is essential for maintaining physical health and psychological resilience. Because sleepwear remains in direct contact with the skin throughout the night, it may affect thermoregulation and comfort and, thereby, influence sleep. This randomized two-period, two-sequence crossover study investigated whether sleepwear infused with nanodiamond and nanoplatinum particles (DPV576) could improve sleep quality and promote fatigue recovery under free-living conditions. Fourteen healthy men (23.9 ± 1.7 years) wore DPV576 sleepwear and visually indistinguishable standard polyester sleepwear for one week each, separated by a one-week washout. Sleep was assessed using a wearable ECG-based actigraphy device; trained researchers additionally performed manual rescoring to verify automated outputs, including independent determination of sleep onset latency. Subjective sleep was assessed daily using the Sleep Quality Index of Daily Sleep and a visual analog scale; exploratory outcomes included voice-derived biomarkers and pre-/post-sleep grip strength. In manual rescoring, DPV576 was associated with higher sleep efficiency (93.0 ± 0.9% vs. 89.5 ± 1.5%, p < 0.05), fewer awakenings (8.4 ± 1.3 vs. 10.7 ± 1.4, p < 0.01), and shorter wake after sleep onset (30.4 ± 4.7 vs. 41.6 ± 6.0 min, p < 0.01), whereas total sleep time did not differ significantly (p = 0.096). These findings suggest that one-week use of DPV576 sleepwear may improve wearable ECG-derived sleep consolidation in young men, supporting a nonpharmacological wearable strategy to enhance sleep efficiency in everyday settings. Full article

Background/Objectives: While intravitreal administration allows for increased ocular exposure to anti-TNF-α monoclonal antibodies, there is still a need for developing delivery systems able to prolong ocular drug exposure and alleviate patient compliance and safety concerns because of repeated injections. Therefore, the objective of this work was to guide the design of sustained-release formulations of anti-TNF-α monoclonal antibodies for intravitreal administration through a model-based strategy in non-infectious uveitis in the preclinical setting. Methods: Using an in-house-developed anterior uveitis disease model in rats, an intravenous reference dose reducing free TNF-α by 90% at the biophase was established. Intravitreal administrations of sustained-release formulations every 24 weeks were then simulated for adalimumab, golimumab and infliximab to evaluate TNF-α kinetics in the anterior chamber of the eye at different release rates. The selected sustained-release formulation was further evaluated for possible formulation issues causing device emptying before the next administration. Results: Intravitreal administration of sustained-release formulations releasing adalimumab, golimumab or infliximab at 1.802, 0.979 and 1.442 μg/week, respectively, met the predefined criteria of ≥90% reduction in free TNF-α at the biophase. TNF-α levels in aqueous humour were anticipated to be the most sensitive to detect possible formulation issues. Formulation emptying 10, 4 or 8 weeks for adalimumab, golimumab and infliximab, respectively, before next administration triggered TNF-α reaching pathological levels at week 24 post-dose. Conclusions: This work underscores the potential of new approach methodologies in the preclinical drug development of sustained-release formulations for intravitreal administration in ocular inflammatory disorders with less animal testing and without compromising the accuracy of model-informed predictions for human translation. Full article

As robotics prehension systems and virtual reality applications are in constant evolution, the need for high-fidelity haptic interaction increases. This helps ensure and enhance user immersion and handling precision. While commercial haptic interfaces offer high performance, their prohibitive cost limits their widespread adoption in general-purpose robotics. Furthermore, many low-cost solutions suffer from limited transparency, where the operator constantly fights the friction of the actuator even during free motion. This article presents the design and development of an innovative, cost-effective master–slave robotic system aimed at democratizing efficient haptic feedback devices. The solution is intended for remote manipulation of objects with a maximum mass of 1 kg, while limiting the gripping force to 50 N, thus ensuring the integrity of objects being manipulated. The device includes a master haptic module in the form of a clamp that reproduces the thumb–index–middle finger gripping motion performed by the user. The system relies on a custom haptic interface measuring the angular position of the master gripper, which is transmitted in real time to the slave gripper, so as to adjust the position of the clamp accordingly, thus optimizing the grasping control loop. As soon as an object is detected, using a force sensor integrated into the slave gripper, the master motor renders a resistive force, preventing the user from closing the haptic module. The other part of the system is the slave mechanical gripper with three fingers, each with three phalanges based on human anatomy, allowing the clamp to mechanically conform to irregular object geometries with a single actuator. The last but not least innovative aspect lies in the implementation of a current sensor, which provides the haptic feedback. The force applied by the user is reproduced by the slave gripper using current sensors, eliminating the need for expensive force-torque sensors while maintaining a responsive feedback loop. Full article

Personal thermal management systems, particularly neck fans, are increasingly popular for providing hands-free, localized cooling to enhance user comfort. We investigate the aerodynamic performance of compact forward-curved centrifugal impellers (<50 mm in diameter) with 30, 28, and 24 blades, selected through benchmarking of commercial products. A baseline impeller and casing were reverse engineered by using 3D scanning and CAD modeling methods, followed by blade count modifications under consistent geometric constraints. CFD simulations in ANSYS Workbench 19.1 were conducted to examine velocity fields, pressure distribution, and flow rate. Results indicate that blade number significantly influences airflow and efficiency: the 28-blade impeller achieved the highest outlet velocity, while the 30-blade configuration provided smoother pressure recovery but higher flow resistance. These insights aid the design of more efficient wearable cooling devices. Full article

Background/Objectives: MRI-guided neurovascular interventions could benefit from lower-field systems due to reduced magnetic and radiofrequency hazards. However, safety and practical visibility of commonly used neurointerventional devices at 0.55 T remain insufficiently characterized. We evaluated magnetic field interactions, RF-induced heating, and qualitative device visibility in 11 commercially available and commonly used neurovascular devices on a 0.55 T MRI system. Methods: Eleven devices, including stent retrievers, guidewires, catheters, and one embolization implant, were tested at 0.55 T. Magnetostatic interactions were quantified using the American Society for Testing and Materials (ASTM)-guided deflection methods for translational force (ASTM-F2052) and a two-string suspension apparatus for torque (adapted from Stoianovici et al.). RF-induced heating was measured in an in vitro perfused cerebral vessel phantom using a 15 min high-specific absorption rate spin echo sequence under static and flow conditions. Qualitative device visibility was assessed using a turbo spin echo (TSE) and balanced steady-state free precession (bSSFP) imaging on each device individually. Results: Eight of eleven devices passed the translational force test, while three devices (D, E, and G), containing significant ferromagnetic components, failed with deflection angles > 45°. Eight devices passed torque testing, remaining below the critical threshold in all rotation positions; three devices (D, G, and J) failed by exceeding the 54° criterion, including one guidewire and two devices with braided/coiled metallic structures. Under static conditions, RF-induced heating ranged from negligible to 10.4 °C (maximum in device D) and generally decreased under flow; in the flow configuration, temperature rise remained below 2 °C for 6/11 devices. Qualitative imaging performance differed by sequence, with bSSFP enabling improved delineation of device structure (best for devices A, C, and H), whereas devices D, E, F, and J produced extensive signal voids that precluded reliable visualization in both sequences. Overall, three devices satisfied all safety criteria while remaining clearly visible under MRI. Conclusions: Devices that pass safety thresholds at 0.55 T can serve as candidates for further sequence optimization and preclinical workflow development, enabling the design of low-SAR, device-compatible imaging protocols tailored for neurointerventional workflows. These results provide key safety data supporting the feasibility of MR-guided neurovascular procedures at 0.55 T. Full article

Optical klystrons have been developed in storage ring free-electron lasers (FELs) as insertion devices to increase the FEL gain in a straight section with limited length. By adjusting the magnetic field in the dispersion section of the optical klystron to shift the relative delay between the electron bunch and FEL pulse from an integer multiple of the FEL wavelength, FELs can oscillate at two wavelengths. The electron density of the electron bunch that interacts with the FEL pulse in a small-signal regime is modulated at the FEL wavelength period. When the FEL oscillates simultaneously at two wavelengths, the electron density of the electron bunch beats through the modulation with two periods. This beat generates long-wavelength coherent edge radiation at a bending magnet located in the straight section containing the optical klystron. Difference-frequency waves induced by dual-wavelength ultraviolet free-electron lasers generate a high-intensity mid-infrared monochromatic beam. Our findings will lay the foundation for the development of the difference-frequency waves of soft X-rays and extreme ultraviolet light using hard X-ray FELs. Full article