Effects of Sleepwear Incorporating a DPV576 Functional Polyester Fabric on Wearable ECG-Derived Sleep Consolidation: A Randomized Two-Period Crossover Study Under Free-Living Conditions
Highlights
- DPV576 sleepwear improved sleep consolidation vs. control (sleep efficiency ↑; awakenings and WASO ↓).
- The condition effects were detectable using wearable ECG-derived sleep metrics with manual verification.
- Functional textile sleepwear may offer a low-burden, nonpharmacological strategy to enhance sleep efficiency in free-living settings.
- Wearable ECG endpoints combined with manual checks provide a practical evaluation framework for future registered trials of textile interventions.
Abstract
1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Study Design
2.3. Interventions (Figure 1A)

2.4. Outcomes
2.4.1. Pittsburgh Sleep Quality Index (PSQI)
2.4.2. Epworth Sleepiness Scale (ESS)
2.4.3. Post-Randomization Daily Questionnaires
Sleep Quality Index for Daily Sleep (SQIDS)
Visual Analog Scale (Sleep VAS)
2.4.4. Measurements
2.4.5. Manual Scoring
2.4.6. Ancillary Voice-Based Measure
2.4.7. Grip Strength
2.5. Statistical Analysis
3. Results
3.1. Baseline Questionnaire Responses
3.1.1. Pittsburgh Sleep Questionnaire (PSQI)
3.1.2. Epworth Sleepiness Scale (ESS)
3.2. Questionnaire Survey Results
3.2.1. Sleep Questionnaire (SQIDS)
3.2.2. Visual Analog Scale (VAS)
3.3. Objective Sleep Measures: Automated Scoring (Silmee)
3.4. Objective Sleep Measures: Manual Scoring
3.5. Comparing Automated and Manual Scoring
Autonomic Indices (HRV)
3.6. Grip Strength
4. Discussion
Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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| (A) Baseline Questionnaires | |||
|---|---|---|---|
| PSQI category | n | % | |
| ≥6 (potential disturbance) | 8 | 57.1 | |
| <6 (no disturbance) | 5 | 35.8 | |
| ≥10 (more severe) | 1 | 7.1 | |
| ESS category | |||
| 0–5 (no EDS) | 9 | 64.3 | |
| 6–10 (mild EDS) | 5 | 35.7 | |
| ≥11 (severe EDS) | 0 | 0.0 | |
| (B) Condition-Level Questionnaires During the Trial | |||
| Scale | DPV576 | Control | Condition p-Value |
| SQIDS (total) | 4.0 ± 0.4 | 4.0 ± 0.4 | 0.536 |
| VAS—sleep quality (mm) | 37.2 ± 1.2 | 40.1 ± 1.4 | 0.186 |
| VAS—drowsiness (mm) | 39.5 ± 1.4 | 38.0 ± 0.8 | 0.776 |
| VAS—mood (mm) | 32.5 ± 0.8 | 33.9 ± 0.6 | 0.314 |
| VAS—activity (mm) | 33.5 ± 1.2 | 34.1 ± 0.5 | 0.768 |
| DPV576 (n = 14) | Control (n = 14) | Difference | p-Value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SE | Mean | SE | Mean | SE | ||||||
| Sleep Time (min) | 392 | ± | 14 | 419 | ± | 17 | −26 | ± | 12 | 0.053 | |
| Sleep Efficiency (%) 1 | 92.9 | ± | 1.0 | 90.2 | ± | 1.2 | 3.0 | ± | 0.7 | 0.002 | ** |
| Sleep Onset Latency (min) | 20.4 | ± | 4.6 | 21.9 | ± | 3.8 | −1.4 | ± | 5.9 | 0.814 | |
| Deep Sleep Time (min) | 68.5 | ± | 6.3 | 68.0 | ± | 7.0 | 0.5 | ± | 6.0 | 0.938 | |
| Number of Awakenings | 8.2 | ± | 1.2 | 10.6 | ± | 1.4 | −2.4 | ± | 0.6 | 0.002 | ** |
| Time Awake (min) | 29.5 | ± | 4.5 | 41.2 | ± | 6.0 | −11.7 | ± | 3.2 | 0.003 | ** |
| Body Movement Frequency 2 | 0.1 | ± | 0.0 | 0.1 | ± | 0.0 | 0.0 | ± | 0.0 | 0.283 | |
| DPV576 | Control | Difference | p-Value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SE | Mean | SE | Mean | SE | ||||||
| Sleep Time (min) | 399 | ± | 16 | 0.42 | ± | 17 | −23 | ± | 12 | 0.096 | |
| Sleep Efficiency (%) 1 | 93.0 | ± | 0.9 | 89.5 | ± | 1.5 | 3.5 | ± | 1.2 | 0.015 | * |
| Sleep Onset Latency (min) | 14.3 | ± | 2.3 | 20.5 | ± | 4.1 | −6.2 | ± | 4.6 | 0.202 | |
| Deep Sleep Time (min) | 69.0 | ± | 6.3 | 68.7 | ± | 6.9 | 0.4 | ± | 6.3 | 0.954 | |
| Number of Awakenings | 8.4 | ± | 1.3 | 10.7 | ± | 1.4 | −2.3 | ± | 0.6 | 0.001 | ** |
| Time Awake (min) | 30.4 | ± | 4.7 | 41.6 | ± | 6.0 | −11.2 | ± | 3.4 | 0.006 | ** |
| Body Movement Frequency 2 | 0.1 | ± | 0.0 | 0.1 | ± | 0.0 | 0.0 | ± | 0.0 | 0.072 | |
| 1/4 | 2/4 | 3/4 | 4/4 | Type | Time | Type * Time | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Control (dimensionless) | 1.79 | ± | 0.18 | 1.64 | ± | 0.18 | 1.77 | ± | 0.18 | 1.81 | ± | 0.18 | F-value | 0.41 | 0.91 | 0.50 |
| DPV576 (dimensionless) | 1.84 | ± | 0.18 | 1.71 | ± | 0.18 | 1.81 | ± | 0.18 | 2.09 | ± | 0.18 | p-value | 0.3049 | 0.0164 * | 0.3049 |
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Katano, H.; Sugita, M.; Tokuno, S.; Nomura, Y.; Nishino, N.; Higuchi, M.; Iwai, Y.; Matsuki, Y.; Deng, P.; Nishino, S. Effects of Sleepwear Incorporating a DPV576 Functional Polyester Fabric on Wearable ECG-Derived Sleep Consolidation: A Randomized Two-Period Crossover Study Under Free-Living Conditions. Sensors 2026, 26, 2247. https://doi.org/10.3390/s26072247
Katano H, Sugita M, Tokuno S, Nomura Y, Nishino N, Higuchi M, Iwai Y, Matsuki Y, Deng P, Nishino S. Effects of Sleepwear Incorporating a DPV576 Functional Polyester Fabric on Wearable ECG-Derived Sleep Consolidation: A Randomized Two-Period Crossover Study Under Free-Living Conditions. Sensors. 2026; 26(7):2247. https://doi.org/10.3390/s26072247
Chicago/Turabian StyleKatano, Hideki, Masaaki Sugita, Shinichi Tokuno, Yumi Nomura, Naoya Nishino, Masakazu Higuchi, Yusuke Iwai, Yuki Matsuki, Pengyu Deng, and Seiji Nishino. 2026. "Effects of Sleepwear Incorporating a DPV576 Functional Polyester Fabric on Wearable ECG-Derived Sleep Consolidation: A Randomized Two-Period Crossover Study Under Free-Living Conditions" Sensors 26, no. 7: 2247. https://doi.org/10.3390/s26072247
APA StyleKatano, H., Sugita, M., Tokuno, S., Nomura, Y., Nishino, N., Higuchi, M., Iwai, Y., Matsuki, Y., Deng, P., & Nishino, S. (2026). Effects of Sleepwear Incorporating a DPV576 Functional Polyester Fabric on Wearable ECG-Derived Sleep Consolidation: A Randomized Two-Period Crossover Study Under Free-Living Conditions. Sensors, 26(7), 2247. https://doi.org/10.3390/s26072247

