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497 Results Found

  • Article
  • Open Access
42 Citations
6,986 Views
20 Pages

Luteolin-Loaded Elastic Liposomes for Transdermal Delivery to Control Breast Cancer: In Vitro and Ex Vivo Evaluations

  • Mohammad A. Altamimi,
  • Afzal Hussain,
  • Mohammad AlRajhi,
  • Sultan Alshehri,
  • Syed Sarim Imam and
  • Wajhul Qamar

11 November 2021

The study aimed to prepare and optimize luteolin (LUT)-loaded transdermal elastic liposomes (LEL1-LEL12), followed by in vitro and ex vivo evaluations of their ability to control breast cancer. Various surfactants (Span 60, Span 80, and Brij 35), and...

  • Article
  • Open Access
5 Citations
2,454 Views
21 Pages

The integration of human–cyber–physical systems (HCPSs), IoT, digital twins, and big data analytics underpins Industry 4.0, transforming traditional manufacturing into smart manufacturing with capabilities for real-time monitoring, qualit...

  • Article
  • Open Access
383 Views
25 Pages

1 January 2026

This paper presents a hybrid knowledge-based expert system (KBES) designed to predict crack incubation and fatigue life in gear design, serving as both a research tool and an educational resource. While crack growth and initiation are well understood...

  • Article
  • Open Access
5 Citations
4,278 Views
21 Pages

31 December 2021

The plastic industry is undergoing drastic changes, due to the customer sustainability perception of plastics, and the eruption of new processes (such 3D printing) and materials (such as renewably sourced resins). To enable a fast transition to high-...

  • Article
  • Open Access
4 Citations
1,906 Views
17 Pages

1 April 2025

Traditional villages, as repositories of cultural heritage and natural landscapes, have gained increasing prominence in the tourism industry. However, balancing authenticity preservation with visitor satisfaction remains a critical challenge. This st...

  • Feature Paper
  • Article
  • Open Access
288 Views
54 Pages

4 February 2026

Airport digital transformation is commonly approached through technological integration and data-driven optimization, yet such perspectives provide limited insight into system-level reasoning and governance. This paper introduces the cognitive airpor...

  • Article
  • Open Access
1,926 Views
18 Pages

Technological roadmaps are essential tools for managing and planning complex projects, especially in the rapidly evolving field of space exploration. Defined as dynamic schedules, they support strategic and long-term planning while coordinating curre...

  • Article
  • Open Access
47 Citations
6,200 Views
35 Pages

Optimal Genetic Design of Type-1 and Interval Type-2 Fuzzy Systems for Blood Pressure Level Classification

  • Juan Carlos Guzmán,
  • Ivette Miramontes,
  • Patricia Melin and
  • German Prado-Arechiga

15 January 2019

The use of artificial intelligence techniques such as fuzzy logic, neural networks and evolutionary computation is currently very important in medicine to be able to provide an effective and timely diagnosis. The use of fuzzy logic allows to design f...

  • Article
  • Open Access
26 Citations
6,630 Views
16 Pages

22 July 2019

This article addresses the design and real-time implementation of an expert model predictive controller (Expert MPC) for the control of the brackish and seawater desalination process in a pilot-scale reverse osmosis (RO) plant. This pilot-scale plant...

  • Article
  • Open Access
18 Citations
5,050 Views
21 Pages

4 August 2017

In reliability-based and cost-oriented product optimization, the target product reliability is apportioned to subsystems or components to achieve the maximum reliability and minimum cost. Main challenges to conducting such optimization design lie in...

  • Article
  • Open Access
1 Citations
2,213 Views
19 Pages

Robotic Arm Trajectory Planning in Dynamic Environments Based on Self-Optimizing Replay Mechanism

  • Pengyao Xu,
  • Chong Di,
  • Jiandong Lv,
  • Peng Zhao,
  • Chao Chen and
  • Ruotong Wang

29 July 2025

In complex dynamic environments, robotic arms face multiple challenges such as real-time environmental changes, high-dimensional state spaces, and strong uncertainties. Trajectory planning tasks based on deep reinforcement learning (DRL) suffer from...

  • Article
  • Open Access
1,351 Views
20 Pages

13 October 2024

In the traditional decision-making process for product form design, designers and experts often prioritize schemes based on their own knowledge and experience. This approach can lead to an oversight of user preferences, ultimately affecting decision...

  • Article
  • Open Access
5 Citations
4,902 Views
17 Pages

14 April 2016

Knowledge management systems are widely used to manage the knowledge in organizations. Consulting experts is an effective way to utilize tacit knowledge. The paper aims to optimize the match between users and experts to improve the efficiency of taci...

  • Feature Paper
  • Article
  • Open Access
7 Citations
4,054 Views
18 Pages

To reflect the initiative design and initiative of human security management and safety warning, ecological safety assessment is of great value. In the comprehensive evaluation of regional ecological security with the participation of experts, the ex...

  • Review
  • Open Access
12 Citations
5,373 Views
36 Pages

21 April 2021

New functions and requirements of high performance building (HPB) being added and several regulations and certification conditions being reinforced steadily make it harder for designers to decide HPB designs alone. Although many designers wish to rel...

  • Article
  • Open Access
4 Citations
2,590 Views
25 Pages

A Three-State Space Modeling Method for Aircraft System Reliability Design

  • Yao Wang,
  • Fengtao Wang,
  • Yue Feng and
  • Shancheng Cao

25 December 2023

Reliability is an inherent attribute of a system through optimal system design. However, during the aircraft system development process, the reliability evaluation and system function design efforts are often disconnected, leading to a divide between...

  • Article
  • Open Access
11 Citations
5,055 Views
24 Pages

Procedural- and Reinforcement-Learning-Based Automation Methods for Analog Integrated Circuit Sizing in the Electrical Design Space

  • Yannick Uhlmann,
  • Michael Brunner,
  • Lennart Bramlage,
  • Jürgen Scheible and
  • Cristóbal Curio

Analog integrated circuit sizing is notoriously difficult to automate due to its complexity and scale; thus, it continues to heavily rely on human expert knowledge. This work presents a machine learning-based design automation methodology comprising...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,448 Views
21 Pages

8 January 2022

Based on expert system theory and fluid–structure interaction (FSI), this paper suggests an intelligent design optimization system to derive the optimal shape of both the fluid and solid domain of flow channels. A parametric modeling scheme of flow c...

  • Article
  • Open Access
9 Citations
2,319 Views
21 Pages

16 September 2024

Additive manufacturing (AM) has impacted the manufacturing of complex three-dimensional objects in multiple materials for a wide array of applications. However, additive manufacturing, as an upcoming field, lacks automated and specific design rules f...

  • Feature Paper
  • Review
  • Open Access
33 Citations
8,046 Views
16 Pages

Recent Development and Perspectives of Optimization Design Methods for Piezoelectric Ultrasonic Transducers

  • Dongdong Chen,
  • Linwei Wang,
  • Xingjun Luo,
  • Chunlong Fei,
  • Di Li,
  • Guangbao Shan and
  • Yintang Yang

30 June 2021

A piezoelectric ultrasonic transducer (PUT) is widely used in nondestructive testing, medical imaging, and particle manipulation, etc., and the performance of the PUT determines its functional performance and effectiveness in these applications. The...

  • Article
  • Open Access
1,262 Views
26 Pages

Lithium-Ion Battery Lifetime Prediction Model Based on a Fusion Expert Network

  • Yawei Meng,
  • Qiang Sun,
  • Zhi Wang,
  • Qizheng Yang,
  • Yuchen Song,
  • Rui Xie,
  • Quanyi Liu,
  • Yang Lin and
  • Fei Ren

27 November 2025

Accurate prediction of the State of Health (SOH) of lithium-ion batteries is essential for improving the safety and longevity of energy storage systems. This paper introduces ExpertMixer, a novel model based on a fused expert network for SOH estimati...

  • Article
  • Open Access
747 Views
20 Pages

28 October 2025

The inherent spatial inaccessibility of cliff inscriptions and the dilemma between preservation and public access have made digital dissemination essential for their legacy. Using the digital design of the “Shimen Thirteen Inscriptions” i...

  • Article
  • Open Access
1,198 Views
27 Pages

18 February 2025

Bridges are typically designed by reputable, specialized engineering and design companies with years of experience. In these firms, experienced engineers share and pass on their knowledge to younger colleagues. However, when these experts retire, som...

  • Article
  • Open Access
6 Citations
2,030 Views
25 Pages

22 July 2024

Predicting student performance in the future is a crucial behavior prediction problem in education. By predicting student performance, educational experts can provide individualized instruction, optimize the allocation of resources, and develop educa...

  • Article
  • Open Access
39 Citations
5,575 Views
35 Pages

Optimal Design of Interval Type-2 Fuzzy Heart Rate Level Classification Systems Using the Bird Swarm Algorithm

  • Ivette Miramontes,
  • Juan Carlos Guzman,
  • Patricia Melin and
  • German Prado-Arechiga

14 December 2018

In this paper, the optimal designs of type-1 and interval type-2 fuzzy systems for the classification of the heart rate level are presented. The contribution of this work is a proposed approach for achieving the optimal design of interval type-2 fuzz...

  • Article
  • Open Access
23 Citations
6,298 Views
25 Pages

27 January 2022

In the face of an ever-changing global market, companies able to launch new products meeting consumer needs faster than their competitors may not only gain a larger market share, but also shorten the development cycle to reduce costs. However, there...

  • Article
  • Open Access
14 Citations
4,105 Views
34 Pages

9 July 2024

The complexity of quality function deployment (QFD) matrices often hinders efficient decision-making in product design, leading to missed opportunities and extended development times. This study explores the integration of principal component analysi...

  • Article
  • Open Access
2 Citations
756 Views
20 Pages

Design and Performance Test of Variable-Capacity Spoon-Type Oat Precision Hill Seeder

  • Wenxue Dong,
  • Anbin Zhang,
  • Fei Liu,
  • Xuan Zhao,
  • Yuxing Ren,
  • Hongbin Bai,
  • Dezheng Xuan,
  • Xiang Kong,
  • Shuhan Yang and
  • Xu Yang

Conventional oat seeders suffer from poor seeding uniformity, a large coefficient of variation in seed volume, and significant seed wastage. To address these issues, a variable-capacity spoon-type oat precision hill seeder was designed based on the a...

  • Article
  • Open Access
15 Citations
3,002 Views
14 Pages

26 February 2023

Dynamic analysis can consider the complex behavior of mooring systems. However, the relatively long analysis time of the dynamic analysis makes it difficult to use in the design of mooring systems. To tackle this, we present a Bayesian optimization a...

  • Article
  • Open Access
3 Citations
3,847 Views
16 Pages

Learning History with Location-Based Applications: An Architecture for Points of Interest in Multiple Layers

  • Samuli Laato,
  • Sampsa Rauti,
  • Antti Laato,
  • Teemu H. Laine,
  • Erkki Sutinen and
  • Erno Lehtinen

28 December 2020

Location-based applications (LBAs) capture the user’s physical location via satellite navigation sensors and integrate it as part of the digital application. Because of this connection, the real-world environment needs to be accounted for in LBA desi...

  • Article
  • Open Access
6 Citations
2,856 Views
17 Pages

Optimization of Collective Irrigation Network Layout through the Application of the Analytic Hierarchy Process (AHP) Multicriteria Analysis Method

  • César González-Pavón,
  • Carmen Virginia Palau,
  • Juan Manzano Juárez,
  • Vicente Estruch-Guitart,
  • Santiago Guillem-Picó and
  • Ibán Balbastre-Peralta

23 January 2024

On numerous occasions, we often have very little information or must make a decision considering qualitative aspects that are difficult to evaluate. This study focuses on obtaining objective criteria to assist in decision-making in the design phase o...

  • Article
  • Open Access
2 Citations
1,888 Views
23 Pages

8 April 2025

Consumer attitude shift and green transport advocacy in the sharing economy highlight shared two-wheeled electric scooters (STWESs) for short-distance commuting. Current designs often overlook user emotions and aesthetic alignment with product charac...

  • Review
  • Open Access
118 Views
15 Pages

Factors Affecting the Implant Supracrestal Complex: A Consensus Paper from the Global Consensus Meeting Organized by the Osstem Implant Community

  • Marco Tallarico,
  • Francesco Grande,
  • Gianluca Fortunato,
  • Carlotta Cacciò,
  • Soo-young Lee,
  • Young-jin Cho,
  • Kwan-tae Noh,
  • Chikahiro Ohkubo,
  • Felipe Aguirre and
  • Gabriele Cervino
  • + 3 authors

18 February 2026

Aim: To develop clear, evidence-based, and standardized guidelines for the design, selection, and clinical use of implant abutments and prosthetic components in order to optimize the biological, mechanical, and esthetic performance of the implant sup...

  • Article
  • Open Access
1,035 Views
27 Pages

To address the challenges of missed and incorrect segmentation in cabbage head detection under complex field conditions using UAV-based low-altitude remote sensing, this study proposes U-MoEMamba, an innovative dynamic state-space framework with a mi...

  • Article
  • Open Access
5 Citations
1,588 Views
16 Pages

24 March 2025

To address the issues of subjectivity in the selection of design schemes for pocket parks in public building environments, as well as the lack of scientific and objective decision making, a comprehensive TOPSIS method-based optimization decision mode...

  • Article
  • Open Access
14 Citations
3,958 Views
22 Pages

Computer-Aided Engineering Environment for Designing Tailored Forming Components

  • Tim Brockmöller,
  • Renan Siqueira,
  • Paul C. Gembarski,
  • Iryna Mozgova and
  • Roland Lachmayer

27 November 2020

The use of multi-material forming components makes it possible to produce components adapted to the respective requirements, which have advantages over mono-material components. The necessary consideration of an additional material increases the poss...

  • Article
  • Open Access
4,071 Views
21 Pages

30 June 2024

Learning sciences competence refers to a necessary professional competence for educators, which is manifested in their deep understanding of learning sciences knowledge, positive attitudes, and scientific thinking and skills in conducting teaching pr...

  • Article
  • Open Access
16 Citations
8,330 Views
12 Pages

Analysis and Optimization of Grinding Performance of Vertical Roller Mill Based on Experimental Method

  • Chang Liu,
  • Zuobing Chen,
  • Ya Mao,
  • Zhiming Yao,
  • Weili Zhang,
  • Weidong Ye,
  • Yuanyuan Duan and
  • Qiang Xie

23 January 2022

This work concentrates on the energy consumption and grinding energy efficiency of a laboratory vertical roller mill (VRM) under various operating parameters. For design of experiments (DOE), the response surface method (RSM) was employed with the VR...

  • Article
  • Open Access
1,314 Views
21 Pages

26 June 2025

Rendering surface materials to provide realistic tactile sensations is a key focus in haptic interaction research. However, generating texture maps and designing corresponding haptic feedback often requires expert knowledge and significant effort. To...

  • Article
  • Open Access
9 Citations
2,868 Views
10 Pages

Response Surface Methodology Analysis of Energy Harvesting System over Pathway Tiles

  • P. Gothwal,
  • A. Kumar,
  • D. Rathore,
  • R. Mukherji,
  • T. Vetriselvi and
  • S. Anandan

29 January 2023

This paper presents an experimental analysis of the optimization of PZT-based tiles for energy harvesting. The hardware (actual experiment), PZT-based tiles, were developed using 6 × 6 piezoelectric (PZT—lead zirconate titanate) sensors o...

  • Article
  • Open Access
7 Citations
4,326 Views
16 Pages

Dementia Patient Segmentation Using EMR Data Visualization: A Design Study

  • Hyoji Ha,
  • Jihye Lee,
  • Hyunwoo Han,
  • Sungyun Bae,
  • Sangjoon Son,
  • Changhyung Hong,
  • Hyunjung Shin and
  • Kyungwon Lee

(1) Background: The Electronic Medical Record system, which is a digital medical record management architecture, is critical for reliable medical research. It facilitates the investigation of disease patterns and efficient treatment via collaboration...

  • Article
  • Open Access
3 Citations
1,462 Views
23 Pages

An Industrial Internet Security Assessment Model Based on a Selectable Confidence Rule Base

  • Qingqing Yang,
  • Shiming Li,
  • Yuhe Wang,
  • Guoxing Li and
  • Yanbin Yuan

27 November 2024

To mitigate the impact of network security on the production environment in the industrial internet, this paper proposes a confidence rule-based security assessment model for the industrial internet that uses selective modeling. First, a definition o...

  • Article
  • Open Access
17 Citations
7,732 Views
19 Pages

9 March 2017

The traditional hearing aid fitting method, which mainly relies on the audiologist, is timeconsuming and messy. To improve this situation, a self-fitting algorithm based on an improved interactive evolutionary computation (IEC) algorithm and expert s...

  • Article
  • Open Access
685 Views
31 Pages

13 November 2025

Reconfigurable intelligent surfaces (RIS) have emerged as a promising enabler for beyond-5G and 6G networks, offering controllable propagation environments to enhance coverage and spectral efficiency. This study investigates and compares multiple RIS...

  • Article
  • Open Access
16 Citations
4,205 Views
24 Pages

Application of Classic and Novel Metaheuristic Algorithms in a BIM-Based Resource Tradeoff in Dam Projects

  • Milad Baghalzadeh Shishehgarkhaneh,
  • Sina Fard Moradinia,
  • Afram Keivani and
  • Mahdi Azizi

19 October 2022

In recent years, dam construction has become more complex, requiring an effective project management method. Building Information Modeling (BIM) affects how construction projects are planned, designed, executed, and operated. Therefore, reducing exec...

  • Article
  • Open Access
17 Citations
4,579 Views
16 Pages

9 October 2020

University performance has an important effect on the social influence of universities. With increasing emphasis placed on higher education, it is important to improve and optimize university performance management. However, the performance of univer...

  • Review
  • Open Access
4 Citations
4,196 Views
18 Pages

An Expert Opinion on “Glycemic Happiness”: Delineating the Concept and Determinant Factors for Persons with Type 2 Diabetes Mellitus

  • Sanjay Kalra,
  • Ashok Kumar Das,
  • Gagan Priya,
  • Ameya Joshi,
  • Hitesh Punyani,
  • Nareen Krishna and
  • Kumar Gaurav

20 August 2021

The importance of the psychological impact of diabetes is globally well-documented. Evidence suggests that there is a high level of psychosocial burden of diabetes in India. Moreover, there is a lack of relevant knowledge among the patients and careg...

  • Article
  • Open Access
9 Citations
6,991 Views
22 Pages

An Agent-Based Empirical Game Theory Approach for Airport Security Patrols

  • Stef Janssen,
  • Diogo Matias and
  • Alexei Sharpanskykh

Airports are attractive targets for terrorists, as they are designed to accommodate and process large amounts of people, resulting in a high concentration of potential victims. A popular method to mitigate the risk of terrorist attacks is through sec...

  • Article
  • Open Access
5 Citations
2,490 Views
19 Pages

Expert System for Neurocognitive Rehabilitation Based on the Transfer of the ACE-R to CHC Model Factors

  • Martin Kotyrba,
  • Hashim Habiballa,
  • Eva Volná,
  • Robert Jarušek,
  • Pavel Smolka,
  • Martin Prášek,
  • Marek Malina,
  • Vladěna Jaremová,
  • Jan Vantuch and
  • Petr Kulišťák
  • + 1 author

20 December 2022

This article focuses on developing an expert system applicable to the area of neurocognitive rehabilitation. The benefit of this interdisciplinary research is to propose an expert system that has been adapted based on real patients’ results fro...

  • Article
  • Open Access
1,364 Views
18 Pages

The Response Surface Optimization of the Performance of Modified Polyurethane Membranes for Phenol Removal

  • Ziyi Song,
  • Zheng Fan,
  • Genhui Jing,
  • Peihua Liu,
  • Ruijun Liu and
  • Kanghua Lu

14 January 2025

In this study, polyurethane (PU) filter membranes were modified with MIL-53(Al) in order to improve phenol removal efficiency. First, one-way analysis of variance (ANOVA) was used to determine that modifier dosage and temperature were significant inf...

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