Search Results (296)

Agentic AI systems, possessing capabilities for autonomous planning and action, show great potential across diverse domains. However, their practical deployment is hindered by challenges in aligning their behavior with varied human values, complex safety requirements, and specific compliance needs. Existing alignment methodologies often falter when faced with the complex task of providing personalized context without inducing confabulation or operational inefficiencies. This paper introduces a novel solution: a ‘superego’ agent, designed as a personalized oversight mechanism for agentic AI. This system dynamically steers AI planning by referencing user-selected ‘Creed Constitutions’—encapsulating diverse rule sets—with adjustable adherence levels to fit non-negotiable values. A real-time compliance enforcer validates plans against these constitutions and a universal ethical floor before execution. We present a functional system, including a demonstration interface with a prototypical constitution-sharing portal, and successful integration with third-party models via the Model Context Protocol (MCP). Comprehensive benchmark evaluations (HarmBench, AgentHarm) demonstrate that our Superego agent dramatically reduces harmful outputs—achieving up to a 98.3% harm score reduction and near-perfect refusal rates (e.g., 100% with Claude Sonnet 4 on AgentHarm’s harmful set) for leading LLMs like Gemini 2.5 Flash and GPT-4o. This approach substantially simplifies personalized AI alignment, rendering agentic systems more reliably attuned to individual and cultural contexts, while also enabling substantial safety improvements. Full article

Background/Objectives: Emotional intelligence has emerged as a key factor in shaping nursing performance and care quality, yet its specific mechanisms and impact within the Greek public healthcare context remain underexplored. This study aimed to investigate the role of emotional intelligence in ethical behavior, crisis management, and the perceived quality of care among nurses working in Greek public hospitals. Methods: A cross-sectional survey was conducted among practicing nurses using validated instruments to assess emotional intelligence, ethical compliance, crisis management skills, and care quality. Data were analyzed using covariance-based structural equation modeling (CB SEM) to examine both direct and indirect relationships among variables. Results: The results indicated that emotional intelligence training had a strong and significant effect on nurses’ ethical behavior and their ability to manage critical situations. However, the direct effect of emotional intelligence on the perceived quality of care was not significant; instead, its influence was mediated through improvements in ethics and crisis management. Conclusions: These findings suggest that the benefits of emotional intelligence in nursing are most evident when integrated with supportive organizational practices and ongoing professional development. Overall, this study highlights the need for comprehensive emotional intelligence training and a supportive workplace culture to enhance ethical standards, resilience, and patient care quality in Greek healthcare settings. Full article

Wild-growing edible mushrooms are known to bioaccumulate radionuclides from their environment, particularly the natural isotope potassium-40 (⁴⁰K) and anthropogenic cesium-137 (¹³⁷Cs). However, region-specific data for commercially relevant species in north-eastern Poland remain limited, despite the cultural and economic importance of mushroom foraging and export. This study aimed to assess the radiological safety of wild mushrooms intended for human consumption, with particular attention to regulatory compliance and potential exposure levels. In this study, 230 mushroom samples representing 19 wild edible species were analyzed using gamma spectrometry, alongside composite soil samples collected from corresponding foraging sites. The activity concentration of ¹³⁷Cs in mushrooms ranged from 0.94 to 159.0 Bq/kg fresh mass (f.m.), and that of ⁴⁰K from 64.4 to 150.2 Bq/kg f.m. None of the samples exceeded the regulatory limit of 1250 Bq/kg f.m. for ¹³⁷Cs. The highest estimated annual effective dose was 2.32 µSv from ¹³⁷Cs and 0.93 µSv from ⁴⁰K, with no exceedance of regulatory limits observed in any sample. A strong positive correlation was observed between ¹³⁷Cs activity in soil and mushroom dry mass (Spearman’s Rho = 0.81, p = 0.042), supporting predictable transfer patterns. Additionally, the implications of mushroom drying were assessed considering Council Regulation (Euratom) 2016/52, which mandates radionuclide levels in dried products be evaluated based on their reconstituted form. After such adjustment, even the most contaminated dried samples were found to comply with food safety limits. These findings confirm the radiological safety of wild mushrooms from north-eastern Poland and contribute novel data for a region with limited prior monitoring, in the context of current food safety regulations. Full article

Guaranteeing food safety in the European Union (EU) is a continuing issue affected by diverse national traditions, regulatory power, and consumer culture. Despite the presence of a harmonized regulatory context, there continues to be variability in performance among the 27 member states. This study gives an extensive comparative evaluation of EU food safety based on three indicators: Rapid Alert System for Food and Feed (RASFF) alerts, pesticide maximum-residue-limit (MRL) violation, and per capita food loss. Fuzzy TOPSIS, K-means clustering, and scenario-based sensitivity tests are used to give an extensive appraisal of the performance of member states. Alarming differences are quoted as findings of significance. The highest number of RASFF notifications (212) and percentage of pesticide MRL non-compliance (1.5%) were reported in 2022 by Bulgaria, whereas the lowest values were reported by Estonia and Lithuania—15–20 RASFF notifications and less than 0.6% MRL violation rates. A statistically significant correlation (r = 0.72, p < 0.001) between pesticide MRL violation and food safety warnings was confirmed in favor of pesticide regulation as the optimal predictor of food safety warnings. On the other hand, food loss did not significantly affect safety measures but indicated very high variation (from 76 kg/capita per year in Croatia to 142 kg/capita per year in Greece). These findings suggest that while food loss remains an environmental problem, pesticide control is more central to the protection of food safety. Targeted policy is what the research necessitates: intervention and stricter enforcement in low-income countries, and diffusion of best practice from successful states. The composite approach adds to EU food safety policy discourse through the combination of performance indicators and targeted regulatory emphasis. Full article

Mental health disorders, particularly depression and anxiety, have become increasingly prevalent among elite athletes, exacerbated by factors such as competitive pressure and the Coronavirus Disease 19 (COVID-19) pandemic. This study analyzes trends in the use of antidepressants, anxiolytics, and cannabinoids (delta-9-tetrahydrocannabinol (THC)/cannabidiol (CBD)) among Italian athletes from 2011 to the first half of 2023 (FH2023), referring to anti-doping reports published by the Italian Ministry of Health. Data from 13,079 athletes were examined, with a focus on non-prohibited medications, banned substances, and regulatory impacts, including threshold adjustments for THC since 2013 and the legalization of CBD. The results show fluctuating use of antidepressants/anxiolytics, with peaks in 2021 and the FH2023, coinciding with post-pandemic awareness. Positive THC cases rose following regulatory changes, reflecting socio-cultural trends. Gender disparities emerged, with THC use predominantly among males (e.g., nine males vs. one female in 2013), though female athletes were underrepresented in testing. This study highlights the need for personalized, evidence-based strategies that balance therapeutic efficacy and anti-doping compliance. Clinicians should carefully consider prescribing selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines to address depression and anxiety and should monitor the risks of CBD contamination. Future research should adopt longitudinal, gender-sensitive approaches to refining guidelines and combating stigma in professional sports. Full article

The restoration of gold leaf on sandstone sculptures requires structural stability, aesthetic considerations, and compliance with the principles of cultural heritage preservation. A primary issue is achieving visual and material compatibility between newly restored and original areas. Based on the “Diagnosis–Analysis–Selection–Restoration” methodology, the research team developed a targeted restoration approach for gilded stone sculptures, using the Shakyamuni sculpture at Erfo Temple in Chongqing as a case study. Assessment of the current situation revealed that over 70% of the sculpture’s surface exhibited gold leaf delamination. The composition and structure of the gold-sizing lacquer, lacquer plaster filler, ground layers, and pigments were investigated using SEM-EDS, XRD, Raman spectroscopy, and THM-Py-GC/MS techniques. The results confirmed that the sculpture featured a typical multilayer gilding structure with clear evidence of historical restorations. Considering both material performance and interfacial compatibility, an NHL2/SiO₂/SF016 composite emulsion and traditional lacquer plaster were selected as the optimal materials for reattachment and infill, respectively. A scientific restoration protocol was developed, encompassing gentle cleaning, targeted reattachment and reinforcement, and region-specific repair methods. Principal Component Analysis (PCA) was used to evaluate the influence of temperature and humidity on the curing behavior of lacquer layers. Additionally, a non-invasive gold leaf color-matching technique was developed by controlling the surface roughness of the gold-sizing lacquer, effectively avoiding the damage caused by traditional color-matching methods. Full article

Non-conformities—deviations from established standards or procedures—can significantly impact product quality and process performance. Although various tools and methodologies exist, current research lacks an integrated, deferred, and corrective approach to non-conformance management that bridges day-to-day operations with systematic quality control. The proposed tool aims to address this gap by providing a practical framework that combines batch data processing using the “Daily Challenge” tool with structured problem solving and corrective strategies. It serves as a comprehensive decision-making tool for systematically managing deviations. The methodology begins with identifying non-conformities through data collection and direct observation, followed by focused reporting and active discussion during departmental meetings. Issues are then categorized based on their frequency, operational impact, and resource requirements to determine the appropriate resolution path—whether through immediate correction or detailed analysis using structured tools such as the “Daily Challenge” sheet. It integrates well-established methodologies such as 5M and PDCA into a structured, daily workflow for resolving non-conformities. Implemented solutions are evaluated for effectiveness with ongoing monitoring to ensure continuous improvement. A key feature of this system is the use of the “Daily Challenge” form, which facilitates documentation, accountability, and knowledge retention—helping to reduce the recurrence of similar situations. The case studies illustrate the methodology through two examples: a labeling issue involving the omission of quantity information on product labels due to operator oversight and the management of production downtime caused by equipment and sensor failures. Although a standard existed, the errors revealed the need for reinforced procedures. Corrective actions included revising procedures, retraining personnel, repairing and recalibrating equipment, enhancing maintenance protocols, and using visual documentation to enhance process understanding. The “Daily Challenge” tool provides a replicable framework for managing non-conformities across various industries, aligning operational practices with quality assurance goals. By integrating structured analysis, clear documentation, and corrective strategies, it fosters a culture of continuous improvement and compliance. Full article

Trans fats are linked to numerous chronic diseases and cellular dysfunction; however, Spain has not implemented effective regulatory measures to restrict their presence in food products. This study addressed these gaps by analyzing trans fat content in commercial pastries sold in Spain and their biological impacts on mesenchymal stem cells, further examining its compliance with international guidelines. Also, a novel and scalable method for extracting fatty acids from pastry samples was developed and applied, enabling precise analysis using gas chromatography alongside sensory property assessments. The findings revealed significant variability in TFA levels across samples. To assess the biological implications of these TFAs, mesenchymal stem cells (MSCs) were cultured to perform dose–response experiments using two selected pastry samples with the highest TFA content. Cellular adhesion, cytotoxicity, and proliferation were evaluated through MTT assays, bright-field, and fluorescence staining using FITC and DAPI markers. Results demonstrated dose-dependent impacts of TFAs on MSC viability, including reduced adhesion and proliferation alongside increased cytotoxicity. This study underlines the need for stricter regulatory frameworks to monitor TFA levels worldwide, including in Spain’s food industry. Additionally, it highlights the potential health risks associated with excessive TFA consumption, particularly concerning cellular health and growth mechanisms, which provide insights into its potential bioaccumulation implications. These findings provide a foundation for further research into dietary guidelines and industrial practices aimed at minimizing TFA exposure while promoting public health safety. Full article

Continuous improvement (CI) is vital for Saudi manufacturing firms to remain competitive in the global market. However, cultural factors significantly influence CI adoption. This qualitative study, involving 28 interviews and focus groups with employees from five local manufacturing firms, explored these factors. Seven key cultural themes emerged, including communication, employee wellbeing, talent management, ethics, top management support, organisational learning, and compliance. A conceptual framework was developed to assess a firm’s cultural proximity to an ideal CI state. This framework integrates a diagnostic tool to guide firms in evaluating their cultural landscape and implementing targeted interventions for successful CI adoption. Future research should explore the long-term impacts of cultural shifts on performance and competitiveness. Full article

Occupational safety and health (OSH) training plays a crucial role in preventing workplace accidents, ensuring compliance with legislation, and fostering a safety-oriented culture across all sectors. This article compares traditional OSH training methods with innovative approaches that incorporate interactive elements and virtual reality (VR) technologies, with a particular emphasis on their contributions to sustainability. The study analyzes feedback from training participants across various occupational roles and age groups, focusing on the effectiveness, engagement, and perception of each method. The results demonstrate that interactive training and VR-based training not only enhance participant engagement and improve comprehension of safety procedures but also promote sustainable training practices by reducing the need for physical materials, minimizing travel, and decreasing reliance on extensive on-site infrastructure. These advancements contribute to environmental sustainability within safety training programs. The paper further explores the benefits, challenges, and economic considerations associated with implementing sustainable, technologically enhanced training approaches. The findings suggest that integrating modern, sustainable educational technologies into OSH training leads to more effective knowledge transfer, better preparedness of employees for emergency situations, and a reduction in environmental impact, aligning safety training practices with broader sustainability goals. Full article

This article presents the design process for a modern stage trapdoor, which was designed to optimize the work of cultural facilities personnel and increase the attractiveness of future performances and events. Strength calculations for the supporting structure were carried out in the Soldis DESIGNER program, and based on these, a 3D model of the stage trapdoor was designed and placed in the space of the stage chimney. In order to verify and analyze the strength of the structure, the 3D model was prepared for detailed analysis in the Autodesk Inventor program. Tests were carried out for four load cases of the structure for 15 different load values. Information about the maximum value of the deflection arrow and the maximum stress was obtained. Collected data were organized in tables and displayed in line and column charts, based on which conclusions were drawn. These analyses showed a high degree of compliance between calculations from both programs. It was found that in this type of structure, a detailed analysis in 3D CAD programs is not necessary for the proper design of the supporting structure, which allows for simplification of the design process. The designed trapdoor meets all design requirements and can be implemented as a solution to improve the functionality and aesthetics of the stage’s technical equipment. Full article

Recreational hunting is a highly regulated activity, in part because it can give rise to a variety of deleterious social, environmental, and economic harms. It provides an interesting area for those interested in community safety because of the way in which both formal (e.g., enforcement officers, proscribed areas and times for hunting, licensing, etc.) and informal (e.g., community awareness and education, conservation) methods of crime prevention are applied. And yet, the criminological literature on effective regulation is not only limited but diverse in terms of scope, types of behavior considered (e.g., poaching, wildlife trading, recreation, etc.), and the context that is considered (e.g., geographical, cultural, etc.). In this paper, we present how a crime prevention and compliance response can be used to understand the nature of the issue and the individual and socio-political processes that result in non-compliance with hunting regulations. We present an overview of the status of recreational hunting in an Australian jurisdiction and locate the regulatory issues that arise within the research literature that explores the various motivations that are known to drive illegal hunting. These are then considered in relation to how community-oriented and non-coercive measures might be employed to improve prevent criminal behavior at the primary, secondary, and tertiary levels. Full article

Background: Sepsis remains a significant cause of morbidity and mortality in preterm and low birth weight (LBW) neonates, especially in low- and middle-income countries (LMICs). Lactoferrin, a glycoprotein present in breast milk with antimicrobial activity, is a low-cost, readily available, and promising intervention currently under investigation. The available literature presents conflicting results on the impact of lactoferrin on the risk of late-onset sepsis (LOS). This study evaluated the effectiveness of two doses of bovine lactoferrin (bLF) supplementation in preventing LOS and necrotizing enterocolitis (NEC) in preterm and LBW neonates in Pakistan. Methods: A three-arm, double-blind, placebo-controlled, randomized clinical trial in the neonatal intensive care unit of Aga Khan University was conducted from July 2019 to August 2020. Preterm (28 to 36 + 5 weeks gestational age) and low birth weight (≥1000 g to <2500 g) neonates who established enteral feeding by 72 h were eligible. The exclusion criteria included sepsis before randomization, maternal history of chorioamnionitis or group B streptococcus colonization, and congenital anomalies. Enrolled neonates were randomly assigned in a 1:1:1 ratio using a computer-generated random allocation sequence to receive placebo (D-glucose), 150 mg bLF, or 300 mg bLF mixed with breast milk once daily for 28 days. The study staff, parents, and outcome assessors were blinded to the allocation. The primary outcome was late-onset sepsis from the trial entry to 28 days. The secondary outcome was NEC from the trial entry to 28 days. Neonates were followed weekly for 28 ± 2 days, and episodes of LOS and NEC were recorded. Results: Of 305 neonates enrolled, 102, 102, and 101, respectively, were randomized to receive a placebo (arm A), 150 mg bLF (arm B), and 300 mg bLF (arm C), respectively. Outcome data of 291 participants (99 in arm A, 95 in arm B, and 97 in arm C) were available for inclusion in the intention-to-treat analysis. The frequency of culture-proven sepsis was 8/102 (7.8%) in arm A compared to 1/102 (0.98%) (p = 0.020) in arm B and 5/101 (4.9%) in arm C (p = 0.390). We did not find any difference in episodes of NEC between arms A (n = 3, 3%) and B (n = 0, 0%) (p = 0.087) or between arms A and C (n = 2, 2%) (p = 0.650). We reported compliance rates of 79 (79.79%) in arm A, 78 (82.1%) in arm B, and 82 (84.53%) in arm C for investigational products. Arm C recorded two deaths, but neither was attributed to the intervention. Conclusions: Bovine lactoferrin supplementation did not prevent late-onset sepsis in neonates of preterm and low birth weight in our trial. However, given the small sample size, further trials with larger sample sizes are required to investigate its efficacy in these at-risk groups. Full article

Green banking has become a concept of interest, particularly with the focus on the role played by banks in pursuing Sustainable Development Goal 13 on climate action. This study is distinguished from previous ones in that it aimed at investigating the multi-regional view on green banking practices/activities around the world with a special emphasis on the opportunities and challenges that various banks encounter in different geographical areas. A systematic review approach was adopted based on the Web of Science and Scopus databases, in which 159 articles were retrieved and 62 articles synthesized through a thematic analysis. The research process was demonstrated through a Prisma 2020 flowchart. Key multiregional green banking activities identified include digital banking, green loan or sukuk products for Islam-dominated economies, green services and investments, and financing of green infrastructure. In essence, the implementation of green banking is either directly through active green lending and greening their operations or indirectly through enhancing conditions. The key challenges identified include regulatory handles, social economic and culture hinderances, transition risk and the high cost of compliance, greenwashing concerns, and weak investor confidence. The most prevalent opportunities included green banking as a strategic competitive advantage, emerging market niche, and as a strategy for long-term climate risk management. Full article

The increasing digitalization of the world underscores the critical importance of both social and technical aspects in software engineering practice. While prior research links socio-technical congruence (STC) to positive workstream outcomes, the current convergence of digital products, technologies, and social systems introduces novel and often unpredictable results, driven by the complex interplay of leadership, organizational culture, and software engineering practices operating as a complex adaptive system (CAS). This paper proposes a novel model for adopting socio-cultural practices to bridge the social and technical divide through the lens of STC. The innovation of the model lies in its socio-technical evolutionary journey, built upon dual systems: (1) an analytical System-I focused on enhancing robustness via compliance with Lean and Agile socio-cultural practices, and (2) a holistic System-II emphasizing resilience through an acceptance of interdependence of system actors that requires sense-making techniques. A methodology based on this model was piloted across six case studies: three in an Enterprise IT organization and three in two business units undergoing transformations on Lean and Agile plus DevOps adoption. System-I’s robustness was evaluated through surveys and structured STC maturity assessments (self and guided ones). System-II employed sense-making techniques to foster resilience within the system of work (SoW), laying the groundwork for their evolutionary journeys. The findings reveal a significant need for greater alignment between management (as transformation agents) and software engineering practices. However, the study suggests actionable guidelines, grounded in new principles and mental models for operating within a CAS, to cultivate enhanced resilience and robustness in a VUCA world. Full article