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33 Results Found

  • Article
  • Open Access
14 Citations
3,372 Views
17 Pages

7 August 2021

This paper proposes a two-layer hierarchical longitudinal control approach that optimizes travel time and trajectories along multiple intersections on an arterial under mixed traffic of connected automated vehicles (CAV) and human-driven vehicles (HV...

(This article belongs to the Collection Urban Street Networks and Sustainable Transportation)
  • Article
  • Open Access
11 Citations
4,016 Views
20 Pages

Dapagliflozin Improves Angiogenesis after Hindlimb Ischemia through the PI3K-Akt-eNOS Pathway

  • Li Han,
  • Guoxin Ye,
  • Wenjing Su,
  • Yuankang Zhu,
  • Wenqi Wu,
  • Liangshi Hao,
  • Jing Gao,
  • Zhen Li,
  • Fang Liu and
  • Junli Duan

Recently, the vascular protective effect of anti-diabetic agents has been receiving much attention. Sodium glucose cotransporter 2 (SGLT2) inhibitors had demonstrated reductions in cardiovascular (CV) events. However, the therapeutic effect of dapagl...

  • Article
  • Open Access
4 Citations
2,911 Views
12 Pages

Invasive Assessment of the Myocardial Microcirculation during Beating Heart Coronary Artery Bypass Grafting

  • Marcin Hellmann,
  • Jakub Piotrowski,
  • Mariusz Kaszubowski,
  • Maria Dudziak and
  • Lech Anisimowicz

Coronary artery bypass grafting may be associated with several cardiac complications, including ischemia, acute myocardial infarction, arrhythmias, or hemodynamic instability. Accumulating evidence suggests that well-developed coronary collateral cir...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
6 Citations
3,379 Views
16 Pages

Tetrodotoxin Decreases the Contractility of Mesenteric Arteries, Revealing the Contribution of Voltage-Gated Na+ Channels in Vascular Tone Regulation

  • Joohee Park,
  • Coralyne Proux,
  • William Ehanno,
  • Léa Réthoré,
  • Emilie Vessières,
  • Jennifer Bourreau,
  • Julie Favre,
  • Gilles Kauffenstein,
  • César Mattei and
  • Christian Legros
  • + 3 authors

22 March 2023

Tetrodotoxin (TTX) poisoning through the consumption of contaminated fish leads to lethal symptoms, including severe hypotension. This TTX-induced hypotension is likely due to the downfall of peripheral arterial resistance through direct or indirect...

(This article belongs to the Special Issue Tetrodotoxins: Detection, Biosynthesis and Biological Effects)
  • Article
  • Open Access
15 Citations
4,134 Views
12 Pages

Morphological and Compositional Features of Chronic Internal Carotid Artery Occlusion in MR Vessel Wall Imaging Predict Successful Endovascular Recanalization

  • Jin Zhang,
  • Shenghao Ding,
  • Bing Zhao,
  • Beibei Sun,
  • Qinhua Guo,
  • Yaohua Pan,
  • Xiao Li,
  • Lingling Wang,
  • Jianjian Zhang and
  • Huilin Zhao
  • + 6 authors

Background: We sought to determine if the morphological and compositional features of chronic internal carotid artery occlusion (CICAO), as assessed by MR vessel wall imaging (MR-VWI), initially predict successful endovascular recanalization. Methods...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Case Report
  • Open Access
5 Citations
1 Views
4 Pages

Microemboli Monitoring by Trans-Cranial Doppler in Patient with Acute Cardioemboliogenic Stroke due to Atrial Myxoma

  • Gregory Telman,
  • Orit Mesica,
  • Efim Kouperberg,
  • Oved Cohen,
  • Gil Bolotin and
  • Yoram Agmon

11 March 2010

This is the first reported attempt to examine the emboliogenic potential of cardiac myxoma in patients with acute stroke through the monitoring of microembolic signals (MES) by transcranial doppler. A 43-year old woman was brought to the emergency de...

  • Article
  • Open Access
1,431 Views
13 Pages

Radiomic Assessment of Epicardial Adipose Tissue for the Prediction of Non-Calcified Coronary Atherosclerotic Plaques

  • Carlo Di Donna,
  • Armando Ugo Cavallo,
  • Eliseo Picchi,
  • Mario Laudazi,
  • Massimo Federici,
  • Marcello Chiocchi and
  • Francesco Garaci

Epicardial adipose tissue (EAT) has previously been associated with coronary artery calcium scores, an increased burden of coronary artery disease (CAD), and features of plaque instability. These associations are likely mediated by endocrine and para...

(This article belongs to the Special Issue Feature Papers in Imaging—Second Edition)
  • Article
  • Open Access
5 Citations
3,154 Views
13 Pages

Buried Autologous Breast Reconstruction: Outcomes and Technical Considerations

  • Henrietta Creasy,
  • Isabelle Citron,
  • Timothy P. Davis,
  • Lilli Cooper,
  • Asmat H. Din and
  • Victoria Rose

2 March 2024

The purpose of this study is to compare outcomes in patients undergoing buried and non-buried free flaps for breast reconstruction, in addition to evaluating the safety and reliability of venous flow couplers. A retrospective review was performed of...

(This article belongs to the Special Issue Breast Reconstruction: Clinical Updates and Perspectives)
  • Article
  • Open Access
4 Citations
4,118 Views
13 Pages

Smartphone-Based versus Non-Invasive Automatic Oscillometric Brachial Cuff Blood Pressure Measurements: A Prospective Method Comparison Volunteer Study

  • Lila Delmotte,
  • Olivier Desebbe,
  • Brenton Alexander,
  • Karim Kouz,
  • Sean Coeckelenbergh,
  • Patrick Schoettker,
  • Tuna Turgay and
  • Alexandre Joosten

21 December 2023

Introduction: Mobile health diagnostics have demonstrated effectiveness in detecting and managing chronic diseases. This method comparison study aims to assess the accuracy and precision of the previously evaluated OptiBP™ technology over a fou...

(This article belongs to the Section Methodology, Drug and Device Discovery)
  • Article
  • Open Access
12 Citations
4,536 Views
14 Pages

Is There Still a Role for Two-Phase Contrast-Enhanced CT and Virtual Monoenergetic Images in the Era of Photon-Counting Detector CT?

  • Arne Estler,
  • Konstantin Nikolaou,
  • Stefan O. Schönberg,
  • Fabian Bamberg,
  • Matthias F. Froelich,
  • Fabian Tollens,
  • Niklas Verloh,
  • Jakob Weiss,
  • Marius Horger and
  • Florian Hagen

Background: To compare the diagnostic characteristics between arterial phase imaging versus portal venous phase imaging, applying polychromatic T3D images and low keV virtual monochromatic images using a 1st generation photon-counting CT detector, of...

(This article belongs to the Special Issue Advances in CT Images)
  • Article
  • Open Access
3 Citations
2,549 Views
12 Pages

Soluble ST2 in Patients with Carotid Artery Stenosis—Association with Plaque Morphology and Long-Term Outcome

  • Stefan Stojkovic,
  • Stephanie Kampf,
  • Olesya Harkot,
  • Maja Nackenhorst,
  • Mira Brekalo,
  • Kurt Huber,
  • Christian Hengstenberg,
  • Christoph Neumayer,
  • Johann Wojta and
  • Svitlana Demyanets

Interleukin (IL-33) and the ST2 receptor are implicated in the pathogenesis of atherosclerosis. Soluble ST2 (sST2), which negatively regulates IL-33 signaling, is an established biomarker in coronary artery disease and heart failure. Here we aimed to...

(This article belongs to the Special Issue New Applications in the Diagnosis and Therapy of Diseases)
  • Article
  • Open Access
27 Citations
5,115 Views
11 Pages

Deep Learning-Based Image Reconstruction for CT Angiography of the Aorta

  • Andra Heinrich,
  • Felix Streckenbach,
  • Ebba Beller,
  • Justus Groß,
  • Marc-André Weber and
  • Felix G. Meinel

3 November 2021

To evaluate the impact of a novel, deep-learning-based image reconstruction (DLIR) algorithm on image quality in CT angiography of the aorta, we retrospectively analyzed 51 consecutive patients who underwent ECG-gated chest CT angiography and non-gat...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
901 Views
13 Pages

22 March 2025

Travel time information has become an essential component of everyday commuting. Without such information, schedule delays would increase, leading to inevitable losses in traveler utility. In Korea, dedicated short-range communication transponders th...

(This article belongs to the Section Intelligent Sensors)
  • Article
  • Open Access
2 Citations
1,554 Views
17 Pages

An Open Source Validation System for Continuous Arterial Blood Pressure Measuring Sensors

  • Attila Répai,
  • Sándor Földi,
  • Péter Sótonyi and
  • György Cserey

20 August 2025

The advancement of sensor technologies enables the measurement of high-quality continuous blood pressure signals, which has become an important area in healthcare. The development of such application-specific sensors can be time-consuming, expensive,...

(This article belongs to the Special Issue Advanced Sensing and Signal Processing Technologies for Medical Applications)
  • Article
  • Open Access
477 Views
21 Pages

26 May 2026

Adaptive urban traffic management requires timely recognition of changes not only in total traffic volume but also in turning-demand composition. This study develops a structural-entropy framework for identifying sustained changes in turning-demand s...

(This article belongs to the Section Transportation and Future Mobility)
  • Article
  • Open Access
3 Citations
3,198 Views
18 Pages

Endothelium-Dependent Nitric Oxide-Mediated Vasorelaxant Effects of BPC 157 in Human Internal Mammary Artery

  • Alperen Kutay Yildirim,
  • Ahmet Onur Dastan,
  • Meric Demeli Ertus,
  • Mesher Ensarioglu,
  • Kubilay Karabacak and
  • Bilge Pehlivanoglu

Background/Objectives: Body Protection Compound-157 (BPC 157) is a stable gastric pentadecapeptide with cytoprotective, pro-angiogenic, and nitric oxide (NO)-modulating properties that has gained increasing attention for its therapeutic potential. Al...

(This article belongs to the Section Vascular Medicine)
  • Article
  • Open Access
72 Citations
11,863 Views
15 Pages

30 July 2014

Rhynchophylline (Rhy) is an alkaloid isolated from Uncaria which has long been recommended for the treatment of central nervous diseases. In our study, the neuroprotective effect of Rhy was investigated in a stroke model, namely permanent middle cere...

  • Article
  • Open Access
6 Citations
6,273 Views
15 Pages

Comparability of a Blood-Pressure-Monitoring Smartphone Application with Conventional Measurements—A Pilot Study

  • Annina S. Vischer,
  • Jana Rosania,
  • Thenral Socrates,
  • Christina Blaschke,
  • Jens Eckstein,
  • Yara-Maria Proust,
  • Guillaume Bonnier,
  • Martin Proença,
  • Mathieu Lemay and
  • Thilo Burkard

(1) Background: New cuffless technologies attempting blood-pressure measurements (BPM) offer possibilities to improve hypertension awareness and control. The aim of this study was to compare a smartphone application (app)-based algorithm with office...

(This article belongs to the Special Issue New Progress in Diagnostics of Clinical Hypertension)
  • Article
  • Open Access
718 Views
13 Pages

The Safety and Efficacy of Mechanical Thrombectomy with Acute Carotid Artery Stenting in an Extended Time Window: A Single-Center Study

  • Bartosz Jabłoński,
  • Adam Wyszomirski,
  • Aleksandra Pracoń,
  • Marcin Stańczak,
  • Dariusz Gąsecki,
  • Tomasz Gorycki,
  • Waldemar Dorniak,
  • Bartosz Regent,
  • Michał Magnus and
  • Bartosz Karaszewski
  • + 2 authors

17 January 2026

Background/Objectives: Acute ischemic stroke (AIS) associated with cervical carotid artery pathology remains a therapeutic challenge due to uncertainty regarding emergent carotid artery stenting (eCAS) and the need for intensified antithrombotic ther...

(This article belongs to the Section Translational Medicine)
  • Article
  • Open Access
4 Citations
2,999 Views
12 Pages

Ventricular Tachycardia Has Mainly Non-Ischaemic Substrates in Patients with Autoimmune Rheumatic Diseases and a Preserved Ejection Fraction

  • George Markousis-Mavrogenis,
  • George Poulos,
  • Theodoros Dimitroulas,
  • Aikaterini Giannakopoulou,
  • Clio Mavragani,
  • Vasiliki Vartela,
  • Dionysia Manolopoulou,
  • Genovefa Kolovou,
  • Paraskevi Voulgari and
  • Sophie I. Mavrogeni
  • + 2 authors

Non-sustained ventricular tachycardia (NSVT) is a potentially lethal arrhythmia that is most commonly attributed to coronary artery disease. We hypothesised that among patients with NSVT and preserved ejection fraction, cardiovascular magnetic resona...

(This article belongs to the Special Issue Imaging Cardiac Arrhythmia/Sudden Cardiac Death)
  • Article
  • Open Access
3 Citations
2,458 Views
10 Pages

8 February 2024

Background: We aimed to compared radiation exposure and image quality between tin-filter-based and standard dose thoraco-abdominal computed tomography angiography (TACTA) protocols, aiming to address a gap in the existing literature. Methods: In this...

(This article belongs to the Special Issue Advances in Multimodality Aortic Imaging)
  • Article
  • Open Access
443 Views
33 Pages

29 June 2026

Background/Objectives: Short interdelivery interval (IDI) is associated with adverse perinatal outcomes, but its relationship with objective neonatal acid–base markers, postpartum anemia, and early postnatal depression remains poorly characteri...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
383 Views
14 Pages

Induction-Phase rSO2–MAP Behaviour and Cross-Clamp Desaturation in NIRS-Guided Selective Carotid Endarterectomy: A Retrospective Cohort Study

  • Ilhan Ozgol,
  • Serkan Ketenciler,
  • Cihan Yucel,
  • Melek Yilmaz,
  • Yasar Gokkurt,
  • Ahmet Ozan Koyuncu,
  • Asime Ay,
  • Mehmet Ali Yesiltas and
  • Cennet Yildiz

14 June 2026

Objective: The objectives of this study were to characterise induction-phase regional cerebral oxygen saturation (rSO2)–mean arterial pressure (MAP) dynamics during near-infrared spectroscopy (NIRS)-guided selective carotid endarterectomy (CEA)...

(This article belongs to the Section Vascular Medicine)
  • Article
  • Open Access
3 Citations
4,474 Views
12 Pages

Culprit versus Complete Revascularization during the Initial Intervention in Patients with Acute Coronary Syndrome Using a Virtual Treatment Planning Tool: Results of a Single-Center Pilot Study

  • Deniss Vasiljevs,
  • Natalja Kakurina,
  • Natalja Pontaga,
  • Baiba Kokina,
  • Vladimirs Osipovs,
  • Nikolajs Sorokins,
  • Sergejs Pikta,
  • Karlis Trusinskis and
  • Aivars Lejnieks

31 January 2023

Background and Objectives: The revascularization strategy for percutaneous coronary intervention (PCI) in patients with multivessel (MV) acute coronary syndrome (ACS) remains controversial. Certain gaps in the evidence are related to the optimal timi...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
7 Citations
3,521 Views
18 Pages

NLRP3-Inflammasome Inhibition with IZD334 Does Not Reduce Cardiac Damage in a Pig Model of Myocardial Infarction

  • Max J. M. Silvis,
  • Evelyne J. Demkes,
  • Leo Timmers,
  • Fatih Arslan,
  • Saskia C. A. de Jager,
  • Joost P. G. Sluijter,
  • Arend Mosterd,
  • Dominique P. V. de Kleijn,
  • Lena Bosch and
  • Gerardus P. J. van Hout

28 November 2022

NLRP3-inflammasome-mediated signaling is thought to significantly contribute to the extent of myocardial damage after myocardial infarction (MI). The purpose of this study was to investigate the effects of the NLRP3-inflammasome inhibitor IZD334 on c...

(This article belongs to the Section Molecular and Translational Medicine)
  • Article
  • Open Access
332 Views
18 Pages

Inflammatory Response After Elective PCI and Subsequent Outcomes in Stable Coronary Artery Disease

  • Yalcin Dalgic,
  • Osman Muhsin Celik,
  • Sadiye Nur Dalgic,
  • Furkan Gencer,
  • Mutlu Can Kabaci,
  • Servet Batit,
  • Aziz Inan Celik,
  • Sabiye Yilmaz,
  • Metin Cagdas and
  • Burak Turan
  • + 1 author

25 August 2026

Background/Objectives: Inflammation contributes to atherosclerotic progression and may intensify after percutaneous coronary intervention (PCI). In stable coronary artery disease (CAD), whether post-procedural inflammation is prognostically distinct...

(This article belongs to the Special Issue Coronary Artery Disease: Recent Developments and Emerging Trends)
  • Article
  • Open Access
433 Views
13 Pages

Long-Term Predictors of Major Adverse Cerebrovascular and Cardiac Events After Successful Transradial Chronic Total Occlusion Recanalization: Five-Year Results of the TRACTOR Study

  • Tímea Szigethi,
  • Dorottya Olajos,
  • Levente Molnár,
  • István Ferenc Édes,
  • György Bárczi,
  • Dávid Becker,
  • László Gellér,
  • Béla Merkely and
  • Zoltán Ruzsa

16 July 2026

Background: Transradial access has become a preferred strategy for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) because of lower access site complication rates and increasing feasibility for complex CTO techniques using larg...

(This article belongs to the Special Issue Interventional Cardiology: Advances in Personalized Treatment and Management)
  • Article
  • Open Access
1,266 Views
24 Pages

Repurposing Coronary Risk Scores to Identify Increased Likelihood of Atrial Fibrillation in Chronic Coronary Syndrome

  • Alexandru-Florinel Oancea,
  • Mathilde Leonard,
  • Paula Cristina Morariu,
  • Maria Godun,
  • Alexandru Jigoranu,
  • Ionela-Larisa Miftode,
  • Radu Stefan Miftode,
  • Aurelia Mihaela Nica,
  • Alexandra Rotaru and
  • Mariana Floria
  • + 8 authors

24 March 2026

Atrial fibrillation (AF) frequently coexists with chronic coronary syndrome (CCS), reflecting shared cardiovascular risk factors and structural remodeling pathways. Identifying CCS patients at increased likelihood of AF remains clinically relevant, p...

(This article belongs to the Section Cardiovascular Disease)
  • Article
  • Open Access
110 Citations
15,641 Views
11 Pages

10 October 2019

Background: Smartwatches that are able to record a bipolar ECG and Einthoven leads were recently described. Nevertheless, for detection of ischemia or other cardiac diseases more leads are required, especially Wilson’s chest leads. Objectives:...

(This article belongs to the Special Issue Recent Advances in ECG Monitoring)
  • Article
  • Open Access
566 Views
11 Pages

Carotid Duplex-Derived Markers Across Angiographic Coronary Artery Disease Burden: A Pandemic-Era Real-World Cohort Study

  • Tuna Aras,
  • Armine Grigorian,
  • Mahmoud Tayeh,
  • Adel Aswad,
  • Mohamed Sharkawy,
  • Zaki Almuzakki,
  • Bernhard Dorweiler,
  • Grigore Cernaianu and
  • Payman Majd

5 June 2026

Background: Carotid atherosclerosis is a recognised manifestation of systemic vascular disease, and its association with coronary artery disease (CAD) has been well described. However, previous studies have largely been conducted under conventional d...

(This article belongs to the Special Issue Hypertension and Cardiovascular Disease: Clinical Updates and Perspectives: 2nd Edition)
  • Article
  • Open Access
460 Views
18 Pages

23 August 2026

Flexible pressure sensors serve as core sensing components for wearable health monitoring systems, electronic skins for soft robots, and flexible human–machine interaction devices. Benefiting from the interfacial electric double-layer polarizat...

(This article belongs to the Special Issue Advances in Pressure Sensors)
  • Article
  • Open Access
774 Views
14 Pages

8 July 2026

Background: Chronic obstructive pulmonary disease (COPD) is associated with substantial long-term morbidity and mortality. Peripheral blood flow cytometry may provide exploratory information regarding immune-cell distributions and activation-related...

(This article belongs to the Section Respiratory Medicine)
  • Article
  • Open Access
1 Citations
799 Views
17 Pages

28 June 2026

To address prevalent industrial challenges, including the high cost of fabricating microstructures via photolithography and 3D printing, impurity residues easily generated by conventional physical/chemical pore-forming techniques, and the limited sen...

(This article belongs to the Special Issue Micro- and Nanosensors: Fabrication, Applications and Performance Enhancements, 4th Edition)