Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (4,874)

Search Parameters:
Keywords = cone

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
11 pages, 588 KB  
Article
Investigation of the Prevalence and Characteristics of the Retromolar Canal Using Cone-Beam Computed Tomography in a Turkish Sample
by Fatoş Can, Fahrettin Kalabalık and Emre Aytuğar
Diagnostics 2025, 15(19), 2526; https://doi.org/10.3390/diagnostics15192526 - 7 Oct 2025
Abstract
Background: The aim of this study is to investigate the prevalence of the retromolar canal (RMC) and retromolar foramen (RMF) using cone-beam computed tomography (CBCT), and to evaluate the course and anatomical structure of the RMC. Methods: The study group consisted of CBCT [...] Read more.
Background: The aim of this study is to investigate the prevalence of the retromolar canal (RMC) and retromolar foramen (RMF) using cone-beam computed tomography (CBCT), and to evaluate the course and anatomical structure of the RMC. Methods: The study group consisted of CBCT images of 1008 subjects (541 females and 467 males). The prevalence and types of the RMC, as well as the frequency of the RMF, were analyzed according to age and sex. A significance level of 0.05 was accepted for all statistical analyses. Results: According to the findings, 575 (57.0%) RMCs and 298 (29.5%) RMFs were identified in 1008 subjects. Bilateral RMCs were observed in 327 subjects (32.4%), while unilateral RMCs were present in 248 subjects (24.6%). When 2016 retromolar regions were examined, a total of 902 RMCs and 400 RMFs were identified. No statistically significant difference was observed between the right and left retromolar regions or between sexes regarding the overall prevalence of RMCs (p > 0.05). The most frequently observed RMC type was Type A1, and a statistically significant difference was found between RMC types and sex. Conclusions: This study suggested that the RMC is a common anatomical variation that may have surgical relevance. Due to the presence of a neurovascular bundle passing through it, both the RMC and RMF should be considered in surgical and anesthetic procedures involving the retromolar region. CBCT is a reliable tool for detecting these structures and assessing their morphology. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
Show Figures

Figure 1

18 pages, 7307 KB  
Article
Conic Programming Approach to Limit Analysis of Plane Rigid-Plastic Problems
by Artur Zbiciak, Adam Kasprzak and Kazimierz Józefiak
Appl. Sci. 2025, 15(19), 10729; https://doi.org/10.3390/app151910729 - 5 Oct 2025
Abstract
This paper presents the application of conic programming methods to the limit analysis of plane rigid-plastic problems in structural and geotechnical engineering. The approach is based on the formulation of yield criteria as second-order cone constraints and on the dual optimization problem, which [...] Read more.
This paper presents the application of conic programming methods to the limit analysis of plane rigid-plastic problems in structural and geotechnical engineering. The approach is based on the formulation of yield criteria as second-order cone constraints and on the dual optimization problem, which directly provides collapse mechanisms and limit loads. Two benchmark examples are investigated. The first concerns a deep beam under uniform top pressure, analyzed with linear and quadratic finite elements. The results confirm the ability of the method to reproduce realistic collapse mechanisms and demonstrate the effect of mesh refinement and element type on convergence. The second example addresses the ultimate bearing capacity of a strip footing on cohesive-frictional soil. The numerical implementation was carried out in MATLAB using CVX with MOSEK as the solver, which ensures practical applicability and efficient computations. Different soil models are considered, including Mohr–Coulomb and two Drucker–Prager variants, and the results are compared with the classical Terzaghi solution. Additional elastoplastic FEM simulations carried out in a commercial program are also presented. The comparison highlights the differences between rigid-plastic optimization and incremental elastoplastic analyses, showing that both conservative and liberal estimates of bearing capacity can be obtained. The study shows that conic programming is an efficient and flexible framework for limit analysis of plane rigid-plastic problems, providing engineers with complementary tools for assessing ultimate loads, while also ensuring good computational efficiency. Full article
Show Figures

Figure 1

26 pages, 1656 KB  
Article
Day-Ahead Coordinated Scheduling of Distribution Networks Considering 5G Base Stations and Electric Vehicles
by Lin Peng, Aihua Zhou, Junfeng Qiao, Qinghe Sun, Zhonghao Qian, Min Xu and Sen Pan
Electronics 2025, 14(19), 3940; https://doi.org/10.3390/electronics14193940 - 4 Oct 2025
Abstract
The rapid growth of 5G base stations (BSs) and electric vehicles (EVs) introduces significant challenges for distribution network operation due to high energy consumption and variable loads. This paper proposes a coordinated day-ahead scheduling framework that integrates 5G BS task migration, storage utilization, [...] Read more.
The rapid growth of 5G base stations (BSs) and electric vehicles (EVs) introduces significant challenges for distribution network operation due to high energy consumption and variable loads. This paper proposes a coordinated day-ahead scheduling framework that integrates 5G BS task migration, storage utilization, and EV charging or discharging with mobility constraints. A mixed-integer second-order cone programming (MISOCP) model is formulated to optimize network efficiency while ensuring reliable power supply and maintaining service quality. The proposed approach enables dynamic load adjustment via 5G computing task migration and coordinated operation between 5G BSs and EVs. Case studies demonstrate that the proposed method can effectively generate an optimal day-ahead scheduling strategy for the distribution network. By employing the task migration strategy, the computational workloads of heavily loaded 5G BSs are dynamically redistributed to neighboring stations, thereby alleviating computational stress and reducing their associated power consumption. These results highlight the potential of leveraging the joint flexibility of 5G infrastructures and EVs to support more efficient and reliable distribution network operation. Full article
11 pages, 823 KB  
Article
Closed-Form Solution Lagrange Multipliers in Worst-Case Performance Optimization Beamforming
by Tengda Pei and Bingnan Pei
Signals 2025, 6(4), 55; https://doi.org/10.3390/signals6040055 - 4 Oct 2025
Abstract
This study presents a method for deriving closed-form solutions for Lagrange multipliers in worst-case performance optimization (WCPO) beamforming. By approximating the array-received signal autocorrelation matrix as a rank-1 Hermitian matrix using the low-rank approximation theory, analytical expressions for the Lagrange multipliers are derived. [...] Read more.
This study presents a method for deriving closed-form solutions for Lagrange multipliers in worst-case performance optimization (WCPO) beamforming. By approximating the array-received signal autocorrelation matrix as a rank-1 Hermitian matrix using the low-rank approximation theory, analytical expressions for the Lagrange multipliers are derived. The method was first developed for a single plane wave scenario and then generalized to multiplane wave cases with an autocorrelation matrix rank of N. Simulations demonstrate that the proposed Lagrange multiplier formula exhibits a performance comparable to that of the second-order cone programming (SOCP) method in terms of signal-to-interference-plus-noise ratio (SINR) and direction-of-arrival (DOA) estimation accuracy, while offering a significant reduction in computational complexity. The proposed method requires three orders of magnitude less computation time than the SOCP and has a computational efficiency similar to that of the diagonal loading (DL) technique, outperforming DL in SINR and DOA estimations. Fourier amplitude spectrum analysis revealed that the beamforming filters obtained using the proposed method and the SOCP shared frequency distribution structures similar to the ideal optimal beamformer (MVDR), whereas the DL method exhibited distinct characteristics. The proposed analytical expressions for the Lagrange multipliers provide a valuable tool for implementing robust and real-time adaptive beamforming for practical applications. Full article
Show Figures

Figure 1

23 pages, 3187 KB  
Article
An Experimental and FE Modeling Investigation of the Pull-Out Behavior of Anchoring Solutions in Concrete: A Comparative Study
by Alexandru-Nicolae Bizu, Dorina Nicolina Isopescu, Gabriela Draghici and Igor Blanari
Materials 2025, 18(19), 4596; https://doi.org/10.3390/ma18194596 - 3 Oct 2025
Abstract
This article presents an original experimental and numerical approach to examining the pull-out behavior of fastening systems made of steel bars simultaneously embedded in both ends of concrete samples. This double-embedded configuration simulates a connection between the existing concrete structure and a new [...] Read more.
This article presents an original experimental and numerical approach to examining the pull-out behavior of fastening systems made of steel bars simultaneously embedded in both ends of concrete samples. This double-embedded configuration simulates a connection between the existing concrete structure and a new external exoskeleton, promoting seismic strengthening. Pull-out tests were performed across six specimen configurations combining different concrete strength classes in order to compare the adhesive solution against traditional monolithic cast-in rebar embedments. The adhesive-anchored bars achieved a peak pull-out force of ~28.6 kN, which is about 18% higher than with mixed anchorage (one end adhesive, one end cast-in). All specimens failed in concrete cracking and pull-out cone formation, with no steel bar yielding, indicating that failure was governed by concrete strength. Finite element simulations in ANSYS Explicit Dynamics were validated against these experiments, confirming the observed behavior and enabling the extension of our analysis to broader concrete strength ranges. Overall, the results demonstrate that double-ended adhesive anchorage significantly increases the connection’s load-bearing capacity and ductility compared to mixed configurations. Full article
(This article belongs to the Section Construction and Building Materials)
Show Figures

Graphical abstract

13 pages, 2022 KB  
Article
Assessment of Standing and Felled Tree Measurements for Volume Estimation
by Maria Triantafyllidou, Elias Milios and Kyriaki Kitikidou
Forests 2025, 16(10), 1540; https://doi.org/10.3390/f16101540 - 3 Oct 2025
Abstract
Accurate stem-volume estimation supports inventory, valuation and carbon accounting, but Pressler’s single-section formula has never been tested in the highly productive European-beech forests of the Central Rhodope Mountains, Greece. We quantified the bias of Pressler estimates and developed size-specific correction factors. Sixty Fagus [...] Read more.
Accurate stem-volume estimation supports inventory, valuation and carbon accounting, but Pressler’s single-section formula has never been tested in the highly productive European-beech forests of the Central Rhodope Mountains, Greece. We quantified the bias of Pressler estimates and developed size-specific correction factors. Sixty Fagus sylvatica L. trees felled in 2023–2024 were measured destructively at 1-m intervals. Pressler standing volumes were compared with Smalian-plus-cone reference volumes (hereafter referred to as true volumes) and analysed with generalized additive models. Pressler underestimated true volume (mean bias = −0.088 m3; RMSE = 0.204 m3; MAPE = 21%). Under-estimation increased with diameter. A GAM with DBH and height explained 96.7% of the variance in true volume. We also fit a Random Forest as a complementary check. Multipliers of 1.30 (<25 cm DBH), 1.20 (25–45 cm), 1.30 (45–55 cm) and ≥1.35 (≥55 cm) cut residual error to ≤20% overall and <10% inside the well-sampled 35–45 cm class. A simple DBH-class correction table restores Pressler’s speed while meeting modern accuracy standards for inventory and carbon reporting. Full article
(This article belongs to the Section Forest Inventory, Modeling and Remote Sensing)
Show Figures

Figure 1

24 pages, 4192 KB  
Article
Investigation on Dynamic Thermal Transfer Characteristics of Electromagnetic Rail Spray Cooling in Transient Processes
by Shuo Ma and Hongting Ma
Energies 2025, 18(19), 5254; https://doi.org/10.3390/en18195254 - 3 Oct 2025
Abstract
Electromagnetic Railguns Face Severe Ablation and Melting Risks Due to Extremely High Transient Thermal Loads During High-Speed Launching, Directly Impacting Launch Reliability and Service Life. To address this thermal management challenge, this study proposes and validates the effectiveness of spray cooling technology. Leveraging [...] Read more.
Electromagnetic Railguns Face Severe Ablation and Melting Risks Due to Extremely High Transient Thermal Loads During High-Speed Launching, Directly Impacting Launch Reliability and Service Life. To address this thermal management challenge, this study proposes and validates the effectiveness of spray cooling technology. Leveraging its high heat transfer coefficient, exceptional critical heat flux (CHF) carrying capacity, and strong transient cooling characteristics, it is particularly suitable for the unsteady thermal control during the initial launch phase. An experimental platform was established, and a three-dimensional numerical model was developed to systematically analyze the dynamic influence mechanisms of nozzle inlet pressure, flow rate, spray angle, and spray distance on cooling performance. Experimental results indicate that the system achieves maximum critical heat flux (CHF) and rail temperature drop at an inlet pressure of 0.5 MPa and a spray angle of 0°. Numerical simulations further reveal that a 45° spray cone angle simultaneously achieves the maximum temperature drop and optimal wall temperature uniformity. Key parameter sensitivity analysis demonstrates that while increasing spray distance leads to larger droplet diameters, the minimal droplet velocity decay combined with a significant increase in overall momentum markedly enhances convective heat transfer efficiency. Concurrently, increasing spray distance effectively improves rail surface temperature uniformity by optimizing the spatial distribution of droplet size and velocity. Full article
(This article belongs to the Section J: Thermal Management)
Show Figures

Figure 1

12 pages, 662 KB  
Article
Accuracy of Patient Setup Using Surface Guided Radiotherapy (SGRT) for Abdominal Malignancies
by Varvara Sotiropoulou, Stefanos Kachris and Michalis Mazonakis
Methods Protoc. 2025, 8(5), 119; https://doi.org/10.3390/mps8050119 - 3 Oct 2025
Abstract
This study aimed to evaluate the placement accuracy and reproducibility of Surface Guided Radiotherapy (SGRT) compared with the conventional tattoo/laser method in patients undergoing radiotherapy for abdominal malignancies. A retrospective analysis was conducted on 43 patients treated with either SGRT (Group A) or [...] Read more.
This study aimed to evaluate the placement accuracy and reproducibility of Surface Guided Radiotherapy (SGRT) compared with the conventional tattoo/laser method in patients undergoing radiotherapy for abdominal malignancies. A retrospective analysis was conducted on 43 patients treated with either SGRT (Group A) or the tattoo/laser technique (Group B). Patients in both groups underwent CBCT to quantify the positioning shifts in the vertical (Svrt), lateral (Slat) and longitudinal (Slng) axes, as well as the total shift. Statistical indicators including median, interquartile range (IQR), and range were calculated, and Mann–Whitney U tests were performed due to non-normal data distribution. Median values in all axes were same between groups: Svrt = 0.4 cm, Slat = 0.2 cm, Slng = 0.4 cm. Group A showed a higher total median shift equal to 0.8 cm versus 0.7 cm of Group B. However, IQRs were smaller in the Group B for all directions and total shift, indicating greater method consistency. Statistically significant differences (p < 0.05) were observed in all axes, except the vertical. These findings suggest that, while SGRT achieves comparable median alignment, its use in a highly variable anatomical region such as the abdomen may be associated with greater setup variability. Full article
(This article belongs to the Section Biomedical Sciences and Physiology)
Show Figures

Figure 1

16 pages, 1417 KB  
Article
Flammability and Thermal Properties of Rigid Polyurethane Foams Modified with Waste Biomass and Ash
by Anna Magiera, Monika Kuźnia, Rafał Stanik, Katarzyna Kaczorek-Chrobak, Maik Gude and Bartłomiej K. Papis
Materials 2025, 18(19), 4570; https://doi.org/10.3390/ma18194570 - 1 Oct 2025
Abstract
The increasing demand for sustainable construction materials has driven interest in utilizing waste biomass within polymer composites. Rigid polyurethane foams, widely valued for thermal insulation, exhibit a significant flammability issue. This study investigates the impact of incorporating various waste biomass materials, including brewers’ [...] Read more.
The increasing demand for sustainable construction materials has driven interest in utilizing waste biomass within polymer composites. Rigid polyurethane foams, widely valued for thermal insulation, exhibit a significant flammability issue. This study investigates the impact of incorporating various waste biomass materials, including brewers’ spent grain, coffee grounds, and soybean husk and their combustion ashes on the selected properties of rigid polyurethane foams. The primary objective is to assess the potential of these eco-friendly additives as replacements for traditional raw materials, aiming to enhance fire resistance and thermal stability and thereby promoting circular economy principles in the construction sector. Composite foam samples were fabricated using a mixing and casting technique, incorporating 5% wt. of fillers into the polymer matrix. Thermal stability and flammability were evaluated using cone calorimetry and thermogravimetric analysis. The findings indicated that while biomass inclusion did not significantly improve char formation, the addition of ash substantially increased char yield, a critical factor in fire suppression. Although biomass and ash may influence flammability, they do not inherently bolster the intrinsic thermal stability of the polyurethane matrix itself. Full article
Show Figures

Figure 1

19 pages, 1061 KB  
Systematic Review
Autologous Tooth-Derived Biomaterials in Alveolar Bone Regeneration: A Systematic Review of Clinical Outcomes and Histological Evidence
by Angelo Michele Inchingolo, Grazia Marinelli, Francesco Inchingolo, Roberto Vito Giorgio, Valeria Colonna, Benito Francesco Pio Pennacchio, Massimo Del Fabbro, Gianluca Tartaglia, Andrea Palermo, Alessio Danilo Inchingolo and Gianna Dipalma
J. Funct. Biomater. 2025, 16(10), 367; https://doi.org/10.3390/jfb16100367 - 1 Oct 2025
Abstract
Background: Autologous tooth-derived grafts have recently gained attention as an innovative alternative to conventional biomaterials for alveolar ridge preservation (ARP) and augmentation (ARA). Their structural similarity to bone and osteoinductive potential support clinical use. Methods: This systematic review was conducted according to PRISMA [...] Read more.
Background: Autologous tooth-derived grafts have recently gained attention as an innovative alternative to conventional biomaterials for alveolar ridge preservation (ARP) and augmentation (ARA). Their structural similarity to bone and osteoinductive potential support clinical use. Methods: This systematic review was conducted according to PRISMA 2020 guidelines and registered in PROSPERO (CRD420251108128). A comprehensive search was performed in PubMed, Scopus, and Web of Science (2010–2025). Randomized controlled trials (RCTs), split-mouth, and prospective clinical studies evaluating autologous dentin-derived grafts were included. Two reviewers independently extracted data and assessed risk of bias using Cochrane RoB 2.0 (for RCTs) and ROBINS-I (for non-randomized studies). Results: Nine studies involving 321 patients were included. Autologous dentin grafts effectively preserved ridge dimensions, with horizontal and vertical bone loss significantly reduced compared to controls. Histomorphometric analyses reported 42–56% new bone formation within 4–6 months, with minimal residual graft particles and favorable vascularization. Implant survival ranged from 96–100%, with stable marginal bone levels and no major complications. Conclusions: Autologous tooth-derived biomaterials represent a safe, biologically active, and cost-effective option for alveolar bone regeneration, showing comparable or superior results to xenografts and autologous bone. Further standardized, long-term RCTs are warranted to confirm their role in clinical practice. Full article
(This article belongs to the Special Issue Property, Evaluation and Development of Dentin Materials)
Show Figures

Figure 1

9 pages, 660 KB  
Article
Mixed-Reality Visualization of Impacted Teeth: A Survey of Undergraduate Dental Students
by Agnieszka Garlicka, Małgorzata Bilińska, Karolina Kramarczyk, Kuba Chrobociński, Przemysław Korzeniowski and Piotr S. Fudalej
J. Clin. Med. 2025, 14(19), 6930; https://doi.org/10.3390/jcm14196930 - 30 Sep 2025
Abstract
Background/Objectives: Integrating 3D visualization technologies, including virtual reality (VR), augmented reality (AR), and mixed reality (MR), into dental education may enhance students’ understanding of facial anatomy and clinical procedures. This study aimed to assess dental students’ perceptions of using MR for three-dimensional [...] Read more.
Background/Objectives: Integrating 3D visualization technologies, including virtual reality (VR), augmented reality (AR), and mixed reality (MR), into dental education may enhance students’ understanding of facial anatomy and clinical procedures. This study aimed to assess dental students’ perceptions of using MR for three-dimensional visualizations of impacted teeth. Methods: Cone-beam computed tomography (CBCT) scans of patients with impacted teeth were retrospectively selected from a university clinic database. The CBCT images were processed to adjust contrast for optimal visualization before being uploaded to MR goggles (HoloLens 2). A total of 114 final-year dental students participated, each manipulating the 3D images in space using the goggles. Following this, they completed a seven-question survey on a five-point Likert scale (1 = strongly agree, 5 = strongly disagree), evaluating image quality and the usefulness of 3D visualization. Results: The study group consisted of 29 males and 85 females (mean age = 24.11 years, SD = 1.48). The most favorable responses were for enhanced visualization of the impacted tooth’s position relative to adjacent structures and the inclusion of 3D image visualization as a teaching aid, which benefited students while learning and allowed them to better understand the course of the procedure for exposure/extraction of the impacted tooth, with median scores of 1, indicating a highly favorable opinion. A statistically significant relationship was found between the responses of females and males regarding the quality of the presented image using HoloLens 2 goggles. No significant correlation was found between participants with and without prior experience using VR/MR/AR. No significant correlation was found between age and responses. Conclusions: Students reported an improved understanding of the relationships between impacted teeth and adjacent structures, as well as potential benefits for clinical training. These findings demonstrate a high level of acceptance of MR technology among students; however, further research is required to objectively assess its effectiveness in enhancing learning outcomes. Full article
(This article belongs to the Special Issue Orthodontics: Current Advances and Future Options)
Show Figures

Figure 1

16 pages, 7745 KB  
Article
Transient Knockdown of RORB with Cell-Penetrating siRNA Improves Visual Function in a Proteotoxic Mouse Model of Retinitis Pigmentosa
by Chanok Son, Hyo Kyung Lee, Hyoik Jang, Chul-Woo Park, Yu-sang Lee, Daehan Lim, Dong Ki Lee, Semin Lee and Hyewon Chung
Biomedicines 2025, 13(10), 2392; https://doi.org/10.3390/biomedicines13102392 - 29 Sep 2025
Abstract
Objectives: Retinitis pigmentosa (RP) is commonly initiated by rod photoreceptor degeneration due to genetic mutations, followed by secondary cone loss and progressive blindness. Preserving rod function during the earlier stages of RP is a key therapeutic goal, as rod survival supports cone maintenance [...] Read more.
Objectives: Retinitis pigmentosa (RP) is commonly initiated by rod photoreceptor degeneration due to genetic mutations, followed by secondary cone loss and progressive blindness. Preserving rod function during the earlier stages of RP is a key therapeutic goal, as rod survival supports cone maintenance and delays vision loss. In this study, we investigated the therapeutic potential of transient knockdown of retinoid-related orphan receptor beta (RORB) using a cell-penetrating asymmetric small interfering RNA (cp-asiRORB) in RhoP23H mice, a model of autosomal dominant RP. While the role of RORB in the adult retina remains unclear, prior studies of related nuclear receptors suggest potential involvement in proteostasis. Based on this, we hypothesized that persistent RORB expression may influence photoreceptor homeostasis under degenerative stress. Methods: We first optimized the cp-asiRORB design to enhance gene silencing and cellular uptake. In vitro studies were conducted under proteotoxic stress. In vivo studies involved intravitreal administration of cp-asiRORB in RhoP23H mice. Furthermore, single-cell RNA sequencing of rod photoreceptors was performed. Results: In vitro studies demonstrated that RORB knockdown improved cell viability, reduced apoptosis, and diminished aggresome formation under proteotoxic stress. Intravitreal administration of cp-asiRORB in RhoP23H mice effectively reduced RORB expression in the retina, leading to improved photoreceptor survival and preserved visual function. Single-cell RNA sequencing revealed upregulation of proteasomal subunit genes in cp-asiRORB-treated eyes, indicating enhanced proteostasis. Conclusions: Together, these results demonstrate that transient suppression of RORB mitigates proteotoxic stress and slows RP progression, highlighting a novel RNAi-based therapeutic strategy for retinal degeneration. Full article
(This article belongs to the Section Molecular Genetics and Genetic Diseases)
Show Figures

Graphical abstract

9 pages, 780 KB  
Article
Long-Term Stability and Histologic Evaluation of Orthodontically Driven Osteogenesis (ODO): A Preliminary Retrospective Study
by Federico Brugnami, Simonetta Meuli, Valentina Ventura and Davide Gentile
J. Clin. Med. 2025, 14(19), 6896; https://doi.org/10.3390/jcm14196896 - 29 Sep 2025
Abstract
Background: Orthodontically driven osteogenesis (ODO) is a surgical tunnel modification of periodontally accelerated osteogenic orthodontics (PAOO), combining selective corticotomy with bone grafting in sequential and/or segmental fashion. This is a minimally invasive approach that enhances periodontal health and allows orthodontic tooth movement [...] Read more.
Background: Orthodontically driven osteogenesis (ODO) is a surgical tunnel modification of periodontally accelerated osteogenic orthodontics (PAOO), combining selective corticotomy with bone grafting in sequential and/or segmental fashion. This is a minimally invasive approach that enhances periodontal health and allows orthodontic tooth movement beyond the original alveolar envelope. Considering the lack of long-term three-dimensional data on orthodontically driven osteogenesis (ODO), this study aims to quantitatively assess the long-term stability of alveolar bone and buccal cortical thickness following ODO, using CBCT imaging. The null hypothesis is that ODO does not result in significant changes in alveolar bone volume or cortical thickness over a seven-year follow-up period. Methods: Twenty patients (13 females, 7 males; mean age 27.4 ± 5.3 years) who had undergone orthodontically driven osteogenesis (ODO) using a minimally invasive tunnel approach and segmental corticotomy protocol followed by clear aligner therapy were retrospectively evaluated. The mean follow-up period after treatment was 7 years (range: 5–15 years). Cone beam computed tomography (CBCT) scans were obtained at one year postoperatively (T1) and again at the long-term follow-up visit (T2). Buccal bone thickness measurements were taken at standardized levels (3 mm, 5 mm, and 7 mm apical to the cementoenamel junction) and compared between T1 and T2 to evaluate bone stability over time. In addition, histologic evaluation of the previously grafted area was performed in two patients: one sample was collected during an alveolar ridge augmentation procedure six months after ODO, and the other during orthognathic surgery eight months after ODO. The samples were analyzed to assess new bone formation and integration of graft material. Results: Radiographic analysis showed long term stability of the new bone support. Histologic examination showed newly formed lamellar and reticular bone. Bone marrow showed no inflammatory infiltration, and bone particles were still detectable but incorporated in the newly created bone. Conclusions: Based on these findings, ODO appears to be a promising technique that could induce stable bone osteogenesis. A larger cohort study can enhance the evidence of these promising results to popularize this technique. Full article
(This article belongs to the Special Issue New Insights into Orthodontic Treatment)
Show Figures

Figure 1

21 pages, 2027 KB  
Article
Fast Network Reconfiguration Method with SOP Considering Random Output of Distributed Generation
by Zhongqiang Zhou, Yuan Wen, Yixin Xia, Xiaofang Liu, Yusong Huang, Jialong Tan and Jupeng Zeng
Processes 2025, 13(10), 3104; https://doi.org/10.3390/pr13103104 - 28 Sep 2025
Abstract
Power outages in non-faulted zones caused by system failures significantly reduce the reliability of distribution networks. To address this issue, this paper proposes a fault self-healing technique based on the integration of soft open points (SOPs) and network reconfiguration. A mathematical model for [...] Read more.
Power outages in non-faulted zones caused by system failures significantly reduce the reliability of distribution networks. To address this issue, this paper proposes a fault self-healing technique based on the integration of soft open points (SOPs) and network reconfiguration. A mathematical model for power restoration is developed. The model incorporates SOP operational constraints and the stochastic output of photovoltaic (PV) distributed generation. And this formulation enables the determination of the optimal network reconfiguration strategy and enhances the restoration capability. The study first analyzes the operational principles of SOPs and formulates corresponding constraints based on their voltage support and power flow regulation capabilities. The stochastic nature of PV power output is then modeled and integrated into the restoration model to enhance its practical applicability. This restoration model is further reformulated as a second-order cone programming (SOCP) problem to enable efficient computation of the optimal network configuration. The proposed method is simulated and validated in MATLAB R2019a. Results demonstrate that combining the SOP with the reconfiguration strategy achieves a 100% load restoration rate. This represents a significant improvement compared to traditional network reconfiguration methods. Furthermore, the second-order cone programming (SOCP) transformation ensures computational efficiency. The proposed approach effectively enhances both the fault recovery capability and operational reliability of distribution networks with high penetration of renewable energy. Full article
Show Figures

Figure 1

12 pages, 986 KB  
Article
In Vitro Evaluation of Disinfectants on Gutta-Percha Cones: Antimicrobial Efficacy Against Enterococcus faecalis and Candida albicans
by Tringa Kelmendi, Donika Bajrami Shabani, Aida Meto and Hani Ounsi
J. Clin. Med. 2025, 14(19), 6846; https://doi.org/10.3390/jcm14196846 - 27 Sep 2025
Abstract
Background/Objectives: Periradicular disease is largely microbial in origin. Even gutta-percha (GP) cones manufactured under aseptic conditions can acquire contaminants during handling or storage, undermining otherwise adequate canal preparation. To assess residual antimicrobial activity on GP cones after brief exposure to five endodontic disinfectants: [...] Read more.
Background/Objectives: Periradicular disease is largely microbial in origin. Even gutta-percha (GP) cones manufactured under aseptic conditions can acquire contaminants during handling or storage, undermining otherwise adequate canal preparation. To assess residual antimicrobial activity on GP cones after brief exposure to five endodontic disinfectants: sodium hypochlorite (NaOCl) 1%, 2.5%, 5.25%; chlorhexidine (CHX) 2%; and glutaraldehyde 2% against Enterococcus faecalis and Candida albicans. Methods: Standardized GP cones were dipped for 5–120 s, blotted on neutralizing gauze, and placed on agar inoculated with either organism. Using an agar diffusion approach, inhibition-zone diameters were recorded at 0, 24, and 48 h. Data were summarized using descriptive statistics (means, standard deviations, and 95% confidence intervals) for each disinfectant–dip-time combination. Results: By 24 h, inhibition zones were observed for most disinfectants; for C. albicans, glutaraldehyde 2% showed no measurable effect. At later time points, performance depended on both disinfectant and contact time. For E. faecalis, NaOCl 2.5% and 5.25% yielded the largest zones at 48 h (20–21 mm at 120 s), whereas NaOCl 1% was smaller (10 mm) and glutaraldehyde 2% modest (9 mm). For C. albicans, NaOCl 2.5% and CHX 2% were most effective at 48 h (17–19 mm at 120 s); NaOCl 5.25% was intermediate, NaOCl 1% weak, and glutaraldehyde 2% showed no measurable antifungal effect. Longer immersions (≥45 s) consistently increased inhibition zone diameters. Conclusions: Residual antimicrobial activity on GP cones depends on both the agent and the immersion time. For E. faecalis, higher concentration NaOCl produced the largest zones at short contact time, whereas for C. albicans, CHX 2% and NaOCl 2.5% provided the most reliable carryover. Selecting an appropriate concentration and allowing sufficient dip time may reduce reinfection risk at obturation. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Show Figures

Figure 1

Back to TopTop