Search Results (29,748)

Background: Childhood obesity is a major public health concern associated with adverse metabolic outcomes later in life. Despite increased awareness, unhealthy lifestyle behaviors—including suboptimal diet quality, physical inactivity, insufficient sleep, and unfavorable body composition—remain prevalent in pediatric populations. Effective, child-centered educational tools for early prevention are still limited. Methods: We developed the Lifestyle Tridimensional Pyramid, an educational model integrating nutrition, physical activity, and sleep within a single, three-dimensional framework. The model also addresses body composition by emphasizing the balance between skeletal muscle and adipose tissue and the interdependence of lifestyle behaviors. This narrative review is supported by an umbrella review of 17 systematic reviews and meta-analyses published between 2010 and 2025, synthesizing evidence on lifestyle behaviors of pediatric obesity. Results: High- to moderate-quality evidence indicates that adherence to Mediterranean-style dietary patterns, regular moderate-to-vigorous physical activity, adequate sleep duration, and a healthier body composition might prevent the development of obesity and improved cardiometabolic profiles in children and adolescents. The pyramid provides a structured, visually accessible tool to support lifestyle counseling in pediatric outpatient settings and is adaptable to school- and community-based health promotion. Conclusions: Although prospective validation studies are warranted, the Lifestyle Tridimensional Pyramid represents a practical, evidence-informed framework to support integrated lifestyle education and improve primary and secondary prevention of pediatric obesity. Full article

This study adopts the theory of planned behavior to investigate consumers’ purchasing decisions under extreme weather conditions. Specifically, this paper examines how extreme global weather events motivate consumers to consider purchasing green products and prioritize environmental sustainability in their consumption choices. It further explores whether consumers’ adoption of green products enhances their satisfaction under abnormal global climate conditions, as well as how consumer satisfaction subsequently improves individuals’ mood, anxiety, and cognitive states. Structural equation modeling was employed to test the hypothesized model using data collected from 352 valid respondents in China. As the global community strives to achieve net-zero CO₂ emissions by 2050, numerous firms and manufacturers have incorporated green product concepts to advance sustainable operations. The empirical results reveal that anxiety and cognition are positively related to green purchasing decisions, which in turn exert a positive influence on consumer satisfaction. Based on these findings, this study proposes actionable strategies to promote green consumption behavior by accounting for relevant psychological factors. Full article

Population aging has markedly increased the burden of cancer in older adults, in whom frailty, sarcopenia, and reduced physiological reserve limit tolerance to treatment and worsen clinical outcomes. Aging is accompanied by progressive functional decline and by biological processes such as cellular senescence, characterized by irreversible cell cycle arrest, chronic low-grade inflammation, and impaired immune surveillance. The accumulation of senescent cells and the persistence of a senescence-associated secretory phenotype contribute to tissue dysfunction and generate a microenvironment that favors tumor initiation and progression. Physical exercise has been associated with attenuation of inflammation, improvements in metabolic and immune function, and with lower levels of senescence-related biomarkers. Although aerobic exercise has been extensively studied in this setting, resistance training holds relevance for older adults due to its capacity to counteract sarcopenia, preserve muscle strength and power, and sustain functional independence. Structured and periodized approaches to resistance exercise may further enhance these benefits by delivering targeted stimuli aligned with age-related physiological deficits. Block strength training (BST), a periodized model that concentrates training adaptations into sequential phases of maximal strength, power, and muscular endurance, has demonstrated consistent improvements in functional performance and reductions in frailty risk in community-dwelling older adults. BST improves physical function. It may also influence biological processes related to aging and cancer; however, mechanistic evidence specific to BST remains to be established. We hypothesized that the exercise in block as a targeted, a structured and physiologically grounded resistance training intervention highlights the potential of BST to promote functional aging and healthy. In the case of cancer biology, and the environment near to tumour, the relationship between aging mechanisms in older adults and controlled exercise effects are currently in advance, but mechanistic trials are still lacking. Finally, we propose a novel training method, structured and personalized, that could impact different clinical outcomes in older patients with cancer. Full article

Chemotherapy- and/or radiotherapy-induced oral mucositis (CRIOM) is a common complication in patients with head and neck cancer, driven largely by excessive proinflammatory cytokine signalling and treatment-associated bacterial dysbiosis. This narrative review synthesizes current mechanistic evidence and summarizes emerging therapeutic strategies targeting these pathways. Research indicates that elevated levels of IL-1β, IL-6, TNF, iNOS, and nitric oxide amplify tissue injury and ulceration, while disruption of oral and gut microbial communities, characterized by loss of beneficial commensals and enrichment of pathogenic taxa, further exacerbates mucosal inflammation. Anti-inflammatory agents, including pentoxifylline, atorvastatin, trans-caryophyllene, azilsartan, recombinant human IL-11, and low-level laser therapy have been shown in preclinical models to reduce cytokine levels and promote mucosal healing. Similarly, microbiome-targeted approaches, such as oral microbiota transplantation and multi-strain probiotic formulations, have demonstrated potential in restoring microbial balance and attenuating CRIOM severity, with current evidence including both preclinical and clinical studies. Overall, current findings highlight cytokine toxicity and dysbiosis as synergistic drivers of CRIOM and support anti-inflammatory and microbiome-modulating strategies as promising adjunctive approaches; however, further well-designed clinical studies are required to validate their efficacy and guide clinical translation. Full article

The salinization of natural grasslands is a growing global concern. The Songnen Plain in northeastern China represents a typical soda–saline grassland region, yet an integrated understanding of how salinization reshapes plant, soil, and microbial components in this ecosystem remains limited. In this study, we investigated plant community characteristics, soil physicochemical properties, and soil microbial communities across a salinity gradient (from non-saline to extremely severe saline) using field surveys, laboratory analyses, and structural equation modeling (SEM). Our results showed that vegetation species diversity, the Shannon–Wiener index, and Simpson’s index all decreased from mild to severe salinization. Soil nutrient indicators, including total nitrogen (TN), total phosphorus (TP), and total potassium (TK), significantly decreased with increasing salinity. SEM revealed that plant community diversity had a significant positive effect on soil microorganisms, whereas soil properties, particularly available potassium (AK) and electrical conductivity (EC), exerted significant negative effects on microbial diversity. Together, these results provide an integrated view of how salinization restructures plant–soil–microbe interactions across the Songnen Plain grasslands. These findings improve understanding of saline–alkali grassland degradation from a plant–soil–microbe perspective and provide a theoretical basis for ecosystem restoration in this region. Full article

Falls are a leading cause of morbidity, loss of independence, and diminished quality of life among older adults, particularly in underserved ethnic minority populations. Physical activity interventions such as Tai Chi (TC) have been shown to improve balance and reduce the risk of falls. However, the influence of psychosocial factors in maximizing these benefits remains underexplored. This study examined the effectiveness of a community-based TC intervention and the role of psychosocial support in enhancing physical health outcomes among Latino older adults at risk of falling. Twenty-eight subjects were recruited to complete a 12-week TC program, and 23 participants with complete outcome data were included in the data analysis. Balance performance was assessed using the Timed Up and Go (TUG) Test at baseline, immediately after the 12-week intervention, and at a 12-week follow-up assessment (24 weeks from baseline). Psychosocial support was measured using the Norbeck Social Support Questionnaire. Linear mixed models were used to analyze changes in TUG scores and the moderating effect of psychosocial support. Results showed that participants with higher levels of psychosocial support showed significantly greater changes in balance than those with lower support scores (p < 0.05) immediately after the intervention program; these improvements were not maintained at follow-up. The findings should be interpreted cautiously, given the single-group design without a control group. Overall, the results highlight the importance of incorporating psychosocial components into health intervention programs for older adults, suggesting that supportive environments may be associated with improvements in both physical health and psychosocial well-being in aging minority populations. Full article

To unveil the underlying risk structures in complex industrial systems, this paper proposes a hybrid analytical framework that integrates BERTopic modeling, a large language model (LLM), and social network analysis (SNA). This framework aims to extract systemic safety intelligence from unstructured accident reports. It first employs BERTopic to identify latent causal topics based on 745 Chinese accident investigation reports and utilizes DeepSeek-V3.1 (LLM) for semantic refinement and causal mapping of these topics. Subsequently, a semantic network of causal keywords based on positive pointwise mutual information (PPMI) is constructed, and its topological structure is analyzed using SNA methods. The study identifies and analyzes five major risk communities: confined spaces, fire, mining, construction, and road traffic. It reveals that accident causation exhibits the small-world characteristics of multi-factor coupling and non-linearity, with core risk nodes concentrated in systemic inducements such as organizational management and compliance deficiencies. The results demonstrate that this framework effectively identifies the latent systemic risk patterns embedded within the texts, providing methodological support for developing sustainable safety management mechanisms based on design for safety. Full article

Aerosol optical depth (AOD) is a key indicator for quantifying aerosol radiative effects and evaluating air quality. However, atmospheric chemical transport models often exhibit systematic AOD biases, and model capability for column-integrated optical properties is not always consistent with that for near-surface particulate matter concentrations. Here, we evaluate AOD simulated by the Community Multiscale Air Quality (CMAQ) model over five major urban clusters in China, including the Beijing-Tianjin-Hebei (BTH) region, Fenwei Plain (FWP), Sichuan Basin (SCB), Yangtze River Delta (YRD), and Pearl River Delta (PRD), using satellite retrievals from the Moderate Resolution Imaging Spectroradiometer (MODIS), ground-based retrievals from the Aerosol Robotic Network (AERONET), and vertical extinction profiles from the Cloud–Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO). CMAQ reproduces the major spatial patterns and exhibits relatively small biases in near-surface PM_2.5. However, it persistently underestimates AOD relative to MODIS, with the largest negative bias occurring in April (i.e., a typical spring month). This contrast indicates a pronounced inconsistency between column-integrated aerosol amount and surface mass density. Relative to AERONET, CMAQ shows a negative bias (NMB = −38%), whereas MODIS shows a positive bias (NMB = 56%), suggesting that both model and retrieval uncertainties contribute to the CMAQ–MODIS disagreements. CALIPSO-constrained vertical analysis further suggests that insufficient extinction above the planetary boundary layer (PBL) is an important contributor to the negative AOD bias, although the relative roles of boundary-layer and upper-layer contributions vary across regions, underscoring the importance of accurately representing aerosol vertical transport and optical processes. These results indicate that evaluations based solely on surface observations may fail to fully capture the overall structure of AOD errors, particularly given the clear differences between near-surface mass concentrations and column optical properties, which vary across regions. This also highlights the importance of improving the representation of aerosol vertical transport and optical processes in chemical transport models. Full article

Corporate reputation teams rely on media monitoring and qualitative research, both limited in speed and coverage when digital narratives form rapidly. This paper proposes SAPIENT (Sentinel-Augmented Population Intelligence for Emerging Narrative Tracking), a multi-agent system that links a sentinel layer over public text streams with a simulation layer that runs moderated, repeatable in silico focus-group sessions. The sentinel layer ingests social media, news, and forum text to produce a compact signal state (topics, sentiment, anomaly scores, risk labels), which conditions the simulation layer through an orchestrator. Persona agents and a moderator follow an Agentic Focus Group (AFG) protocol with repeated runs, variance reporting, and human review gates. We describe four sustainability communication scenarios: greenwashing backlash prediction, greenhushing risk assessment, campaign pre-testing, and crisis communication simulation. Nine experiments span 280 AFG runs across 20 conditions, three LLM backends (Claude Sonnet 4, GPT-4o, and Gemini 2.5 Flash), and a preregistered pilot human validation study with 54 participants. Signal conditioning improved simulation specificity ($p=0.012$). Cross-lingual sessions revealed a sentiment asymmetry between English and Turkish ($p=0.001$) with preserved persona rank ordering ($r=0.81$, $p=0.015$). Cross-model comparison showed consistent persona differentiation across all three backends (Pearson $r>0.92$, $p<0.002$ for all pairs). Sentiment was robust to prompt paraphrasing ($p=0.061$, n.s.), though credibility was sensitive to prompt wording ($p<0.001$). All significant results from Experiments 1–8 survived Benjamini–Hochberg correction. A preregistered pilot with 54 human participants on Prolific replicated the predicted credibility ranking across framing variants ($p=0.004$) but not the sentiment ranking, identifying a specific calibration target for future work. Full article

This study examines institutional processes in digital justice through a mixed conceptual approach that integrates bibliometric analysis and technology-adoption modeling, incorporating artificial intelligence (AI) as a projected component rather than an implemented system. A corpus of approximately 200 Scopus-indexed documents (2003–2024) was analyzed, identifying five dominant thematic clusters: advanced technologies, institutional justice, digital government, judicial information management, and digital criminal justice. The results reveal persistent gaps in the literature, particularly in rural and underserved communities, where connectivity barriers and the limited application of adoption models hinder inclusive digital transformation. As an institutional contribution, the study presents the conceptual design of the digital solution “Travel Permits—Accessible Justice”, developed under a Service-Oriented Architecture (SOA) and projected for future integration with AI-supported components to automate judicial authorizations through biometric validation, electronic signatures, and digital delivery. To evaluate its potential acceptance, the Technology Acceptance Model (TAM) is analytically adapted and extended to the community-based judicial context, framing institutional learning processes as a prospective form of learning analytics focused on user interaction, perceived usefulness, perceived ease of use, and behavioral intention. Taken together, the integration of bibliometric evidence with an extended TAM, along with the projected incorporation of AI-supported institutional learning processes, offers a coherent foundation for future studies on inclusive digital innovation in justice environments. Full article

Objectives: Cardiovascular diseases (CVDs) represent the main global burden of morbidity and mortality, with an accelerated epidemiological transition in regions such as Latin America. The university environment constitutes a period of critical vulnerability due to increased sedentary lifestyles and cardiometabolic risk factors. The objective of this study was to evaluate the cardiovascular risk profile in a university community in the central Andean region of Colombia using anthropometric, haemodynamic and biochemical indicators. Methods: A cross-sectional, observational, and analytical study was conducted on a sample of n = 143 participants (students, teachers, and administrators) aged between 18 and 80 years. Haemodynamic parameters (SBP, DBP, MAP), anthropometric parameters (BMI, % body fat, waist-to-height ratio [WC/W]) and lipid profile were evaluated. Statistical analysis included multiple linear regression models to determine predictors of systolic blood pressure (SBP). Results: Significantly higher levels of SBP were found in the older age groups compared with the younger age groups, reaching stage 1 hypertension levels in the sixth decade. The biochemical profile revealed metabolic deterioration with an atherogenic index (TC/HDL) consistently above the clinical threshold (>4.5) in all groups. The regression model BMI was identified as the statistical predictor with the strongest association with SBP variability in the sample (β = 1.18), followed by age (β = 0.28). A marked sexual dimorphism was observed, with men presenting early haemodynamic risk, while women experienced an accelerated post-menopausal tension and metabolic crisis. Conclusions: The university community presents latent cardiometabolic vulnerability closely linked to modifiable anthropometric factors. These findings underscore the urgency of implementing institutional preventive health policies and weight control intervention programmes to mitigate the future burden of chronic diseases on campus. Full article

This paper reviews recent work on dynamic virtual power plants (DVPPs) using an Energy–Information–Market framework. It addresses the important problem of how DVPPs can support low-inertia power system operation and feeder-level stability under high renewable penetration. First, system-level studies on low-inertia operation and frequency control are used to frame quantitative requirements on rate of change of frequency, nadir, and quasi-steady-state limits. Second, energy-layer models are surveyed, including participation-factor-based DVPP controllers, grid-forming architectures, model-free frequency regulation, and robust frequency-constrained scheduling for allocating virtual inertia and fast frequency response (FFR) across distributed energy resource fleets. Third, information-layer and market-layer models are reviewed, covering stochastic and robust bidding, distribution locational marginal price-based clearing, peer-to-peer and community markets, privacy-preserving coordination, and emerging governance and cybersecurity schemes for DVPP participation. Across these strands, much of the literature remains centred on steady-state active and reactive power dispatch, with dynamic security enforced as constraints rather than formulated as verifiable and tradable services. This review identifies gaps in dynamic metrics and benchmarks, forecasting of available inertia and FFR capacity, market-physics co-design, multi-aggregator interaction, and experimentally validated DVPP implementations. These findings suggest that DVPPs can “sell stability” at the feeder level only through co-designed control, information, and market mechanisms and outline a research roadmap for this purpose. Full article

Short-form video (SFV) platforms have become a central part of older adults’ digital lives, yet their psychological implications remain theoretically contested. Drawing on social empowerment theory, Self-Determination Theory, attachment theory, and the displacement hypothesis, this study examined whether different sources of social support—family, peer, and community—exert differential effects on life satisfaction through SFV engagement and social connectedness. Survey data were collected from 385 community-dwelling Chinese older adults (mean age = 70.6 years) and analyzed using bootstrapped serial mediation models with 5000 resamples. The results revealed clear source differentiation, as family support most strongly predicted SFV engagement and showed the largest total association with life satisfaction, consistent with a social empowerment mechanism. Community participation showed a weaker but still positive association with engagement, whereas peer support was unrelated to engagement. Across pathways, higher SFV engagement was associated with lower social connectedness, while greater social connectedness was associated with higher life satisfaction. However, none of the chained indirect effects reached significance, suggesting that social support influenced life satisfaction primarily through direct rather than serially mediated pathways. These findings demonstrate the importance of disaggregating social support by source and contribute to a more precise framework for understanding older adults’ digital well-being. Full article

Morocco’s recent legalization of industrial and medicinal cannabis has created a rapidly expanding seed-oil sector whose sustainability has yet to be fully assessed. This study applies an environmental life cycle assessment (LCA) in accordance with ISO 14040:2006 and ISO 14044:2006, complemented by a qualitative social responsibility assessment based on ISO 26000:2010, aiming to evaluate the life cycle sustainability of Moroccan cannabis seed oil. Three representative processing chains, traditional artisanal presses, producer cooperatives and regulated industrial plants are compared using a functional unit of 1 kg of cold-pressed oil packaged for local distribution. Inventory data were drawn from field measurements and interviews and were modeled in OpenLCA with background datasets from Ecoinvent 3.8 and Agribalyse v3.1. Impact assessment used the ReCiPe 2016 (H) method at the midpoint level across nine categories (climate change, fossil resource scarcity, water use, freshwater eutrophication, terrestrial acidification, land occupation, carcinogenic, non-carcinogenic human toxicity, and fine particulate matter formation). Sensitivity analyses varied seed yield, electricity mix and transport distances by ±20% to gauge uncertainty. Results show that the cooperative scenario achieves the lowest impacts across nearly all categories because of higher extraction yields (3 kg seed per kg oil), lower energy use (0.54 kWh kg⁻¹ oil) and more effective co-product recovery. In contrast, artisanal extraction requires approximately 1 kg of additional seed input per functional unit compared to optimized scenarios, significantly increasing upstream environmental burdens and causing upstream agricultural burdens to multiply. Industrial facilities perform comparably to cooperatives if powered by renewable electricity. Integrating a semi-quantitative social responsibility assessment reveals that legalization has markedly improved organizational governance, labor conditions, consumer protection and community involvement. Cooperatives display the most balanced social performance, whereas industrial plants excel in governance and quality control. A set of recommendations, including drip irrigation, cultivar improvement, co-product valorisation, renewable energy adoption, eco-designed packaging and cooperative governance, is proposed to enhance the environmental and socio-economic sustainability of Morocco’s emerging cannabis seed-oil industry. Full article