Search Results (37)

Current non-destructive testing (NDT) methods, such as those based on wave velocity measurements, lack the sensitivity necessary to detect early-stage damage in concrete structures. Similarly, common signal processing techniques often assume linearity and stationarity among the signal data. By analyzing wave attenuation measurements using advanced signal processing techniques, mainly Hilbert–Huang transform (HHT), this work aims to enhance the early detection of damage in concrete. This study presents a novel energy-based technique that integrates complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) and Hilbert spectrum analysis (HSA), to accurately capture nonlinear and nonstationary signal behaviors. Ultrasonic non-destructive testing was performed in this study on manufactured concrete specimens subjected to micro-damage characterized by internal microcracks smaller than 0.5 mm, induced through controlled freeze–thaw cycles. The recorded signals were decomposed from the time domain using CEEMDAN into frequency-ordered intrinsic mode functions (IMFs). A multi-criteria selection strategy, including damage index evaluation, was employed to identify the most effective IMFs while distinguishing true damage-induced energy loss from spurious nonlinear artifacts or noise. Localized damage was then analyzed in the frequency domain using HSA, achieving an up to 88% reduction in wave energy via Marginal Hilbert Spectrum analysis, compared to 68% using Fourier-based techniques, demonstrating a 20% improvement in sensitivity. The results indicate that the proposed technique enhances early damage detection through wave attenuation analysis and offers a superior ability to handle nonlinear, nonstationary signals. The Hilbert Spectrum provided a higher time-frequency resolution, enabling clearer identification of damage-related features. These findings highlight the potential of CEEMDAN-HSA as a practical, sensitive tool for early-stage microcrack detection in concrete. Full article

Amid the global transition toward sustainable energy, regional power grids with high wind power penetration are increasingly emerging. The implementation of frequency control is critically essential for enhancing the frequency support capability of grid-connected devices. However, existing studies indicate this may induce ULFOs (ultra-low frequency oscillations). Current research on ULFOs have been predominantly concentrated on hydro-dominated power systems, with limited exploration into systems where thermal power serves as synchronous sources—let alone elucidation of the underlying mechanisms. This study focuses on regional power grids where wind and thermal power generation coexist. Eigenvalue analysis reveals that frequency regulation control of doubly-fed induction generators (DFIGs) can trigger ULFOs. Leveraging common-mode oscillation theory, an extended system frequency response (ESFR) model incorporating DFIG frequency control is formulated and rigorously validated across a range of operational scenarios. Moreover, frequency-domain analysis uncovers the mechanism by which inertia control affects ULFO behavior, and time-domain simulations are conducted to validate the influence of DFIG control parameters on ULFOs. Full article

With the rise of renewable energy penetration in the grid, photovoltaic (PV) panels are connected to the grid via inverters to supply solar energy. Transformer-less grid-tied PV inverters are gaining popularity because of their improved efficiency, reduced size, and lower costs. However, they can induce a path for leakage currents between the PV and the grid due to the absence of galvanic isolation. This leads to serious electromagnetic interference, loss in efficiency, and safety concerns. The leakage current is primarily influenced by the nature of the common mode voltage (CMV), which is determined by the switching techniques of the inverter. In this paper, a novel inverter topology of Hysteresis Controlled H5 with Two Clamping Diodes (HCH5-D2) is derived. The HCH5-D2 topology helps decouple the AC part (Grid) and DC part (PV) during the freewheeling period to make the CMV constant, thereby reducing the leakage current. Additionally, the extra diodes help reduce voltage spikes generated during the freewheeling period and maintain the CMV at a constant value. Finally, a 2.2 kW grid-connected single-phase HCH5-D2 PV inverter system’s MATLAB simulation is presented, showing better results compared to a traditional H4 inverter. Full article

Chinese kale is a native vegetable from the Brassicaceae family that is grown extensively in Southeast Asia and Southern China. Its low genetic transformation and gene editing efficiency hinder gene function research and molecular biology in Chinese kale. CRISPR/Cas9 is a useful tool for plant genome research due to its rapid development and optimization. This study targeted BocPDSs, (BocPDS1, BocPDS2) to establish an effective CRISPR/Cas9 system in Chinese kale. A tandemly arranged tRNA-sgRNA construct was used to express numerous sgRNAs to induce BocPDS1 and BocPDS2 double and single mutations, with a mutation rate of 61.11%. As predicted, several mutant plants showed an albino phenotype with a harbored mutation in an exon and intron region, highlighting the relevance of the intron. The presence of mutations in the intron region suggests that the cleavage process in Chinese kale, utilizing CRISPR/Cas9 shows a preference for AT-rich regions. The distinct and somewhat redundant functions of BocPDS1 and BocPDS2 are demonstrated by the complete albino phenotype of the double mutants and the mosaic albino phenotype of the individual BocPDS1 and BocPDS2 mutants. Specific gene editing modes, including base deletion, base substitution, and base insertion, were identified in the sequence of the target gene. Among them, short nucleotide insertions were the most common type of insertion, with base insertions having the highest frequency (61.54%). Furthermore, no instances of off-target gene editing were detected. The current work demonstrated that the CRISPR/Cas9 gene editing system, which relies on endogenous tRNA processing, can effectively induce mutagenesis in Chinese kale. This finding establishes a theoretical basis and technical backbone for the more effective implementation of CRISPR/Cas9 gene-editing technology in Chinese kale and Brassica plants. Full article

Infertility due to ovarian toxicity is a common side effect of cancer treatment in premenopausal women. Tamoxifen (TAM) is a selective estrogen receptor modulator that prevented radiation- and chemotherapy-induced ovarian failure in preclinical studies. In the current study, we examined the potential regulatory role of long noncoding RNAs (lncRNAs) in the mechanism of action of TAM in the ovaries of tumor-bearing rats receiving cyclophosphamide (CPA) as cancer therapy. We identified 166 lncRNAs, among which 49 were demonstrated to be differentially expressed (DELs) in the ovaries of rats receiving TAM and CPA compared to those receiving only CPA. A total of 24 DELs were upregulated and 25 downregulated by tamoxifen. The identified DELs shared the characteristics of noncoding RNAs described in other reproductive tissues. Eleven of the identified DELs displayed divergent modes of action, regulating target transcripts via both cis- and trans-acting pathways. Functional enrichment analysis revealed that, among target genes ascribed to the identified DELs, the majority were involved in apoptosis, cell adhesion, immune response, and ovarian aging. The presented data suggest that the molecular mechanisms behind tamoxifen’s protective effects in the ovaries may involve lncRNA-dependent regulation of critical signaling pathways related to inhibition of follicular transition and ovarian aging, along with the suppression of apoptosis and regulation of cell adhesion. Employing a tumor-bearing animal model undergoing chemotherapy, which accurately reflects the conditions of mammary cancer, reinforces the obtained results. Given that tamoxifen remains a key player in the management and prevention of breast cancer, understanding its ovarian-specific actions in cancer patients is crucial and requires detailed functional studies to clarify the underlying molecular mechanisms. Full article

Multi-drug therapies are common in cardiovascular disease intervention; however, io channel/pump coordination has not been tested electrophysiologically. Apparently, inward currents were not elicited by Yoda1/10 nM or Dobutamine/100 nM alone in Ah-type baroreceptor neurons, but were by their combination. To verify this, electroneurography and the whole-cell patch-clamp technique were performed. The results showed that Ah- and C-volley were dramatically increased by the combination at 0.5 V and 5 V, in contrast to A-volley, as consistent with repetitive discharge elicited by step and ramp with markedly reduced current injection/stimulus intensity. Notably, a frequency-dependent action potential (AP) duration was increased with Iberiotoxin-sensitive K⁺ component. Furthermore, an increased peak in AP measured in phase plots suggested enhanced Na⁺ influx, cytoplasmic Ca²⁺ accumulation through reverse mode of Na⁺/Ca²⁺ exchanger, and, consequently, functional KCa1.1 up-regulation. Strikingly, the Yoda1- or Dbtm-mediated small/transient Na⁺/K⁺-pump currents were robustly increased by their combination, implying a quick ion equilibration that may also be synchronized by hyperpolarization-induced voltage-sag, enabling faster repetitive firing. These novel findings demonstrate multi-channel/pump collaboration together to integrate neurotransmission at the cellular level for baroreflex, providing an afferent explanation in sexual dimorphic blood pressure regulation, and raising the caution regarding the individual drug concentration in multi-drug therapies to optimize efficacy and minimize toxicity. Full article

Islanding occurs when a load is energized solely by local generators and can result in frequency and voltage instability, changes in current, and poor power quality. Poor power quality can interrupt industrial operations, damage sensitive electrical equipment, and induce outages upon the resynchronization of the island with the grid. This study proposes an islanding detection method employing a Duffing oscillator to analyze voltage fluctuations at the point of common coupling (PCC) under a high-noise environment. Unlike existing methods, which overlook the noise effect, this paper mitigates noise impact on islanding detection. Power system noise in PCC measurements arises from switching transients, harmonics, grounding issues, voltage sags and swells, electromagnetic interference, and power quality issues that affect islanding detection. Transient events like lightning-induced traveling waves to the PCC can also introduce noise levels exceeding the voltage amplitude by more than seven times, thus disturbing conventional detection techniques. The noise interferes with measurements and increases the nondetection zone (NDZ), causing failed or delayed islanding detection. The Duffing oscillator nonlinear dynamics enable detection capabilities at a high noise level. The proposed method is designed to detect the PCC voltage fluctuations based on the IEEE standard 1547 through the Duffing oscillator. For the voltages beyond the threshold, the Duffing oscillator phase trajectory changes from periodic to chaotic mode and sends an islanded operation command to the inverter. The proposed islanding detection method distinguishes switching transients and faults from an islanded operation. Experimental validation of the method is conducted using a 3.6 kW PV setup. Full article

The use of the common mode current for stator winding insulation condition assessment has been extensively studied. Two main approaches have been followed. The first models the electric behavior of ground-wall insulation as an equivalent $RC$ circuit; these methods have been successfully applied to high-voltage high-power machines. The second uses the high frequency of the common mode current which results from the voltage pulses applied by the inverter. This approach has mainly been studied for the case of low-voltage, inverter-fed machines, and has not yet reached the level of maturity of the first. One fact noticed after a literature review is that in most cases, the faults being detected were induced by connecting external elements between winding and stator magnetic core. This paper presents a case study on the use of the high-frequency common mode current to monitor the stator insulation condition. Insulation degradation occurred progressively with the machine operating normally; no exogenous elements were added. Signal processing able to detect the degradation at early stages will be discussed. Full article

Nitrogen-vacancy (NV) centers in diamonds are promising solid-state magnetic sensors with potential applications in power systems, geomagnetic navigation, and diamond NV color center current transformers, in which both high bandwidth and high magnetic field resolution are required. The wide bandwidth requirement often necessitates high laser power, but this induces significant laser fluctuation noise that affects the detection magnetic field resolution severely. Therefore, enhancement of the magnetic field resolution of wide-bandwidth NV center magnetic sensors is highly important because of the reciprocal effects of the bandwidth and magnetic field resolution. In this article, we develop a common mode rejection (CMR) model to eliminate the laser noise effectively. The simulation results show that the noise level of the light-detected magnetic resonance signal is significantly reduced by a factor of 6.2 after applying the CMR technique. After optimization of the laser power and modulation frequency parameters, the optimal system bandwidth was found to be 75 Hz. Simultaneously, the system’s detection magnetic field resolution was enhanced significantly, increasing from 4.49 nT/Hz^1/2 to 790.8 pT/Hz^1/2, which represents an improvement of nearly 5.7 times. This wide-bandwidth, high-magnetic field resolution NV color center magnetic sensor will have applications including power systems, geomagnetic navigation, and diamond NV color center current transformers. Full article

The current literature lacks an effective progressive collapse analysis of a cable dome structure induced by joint damage. In this study, a dynamic analysis was performed using actual construction cases, an ANSYS LS-DYNA analysis platform, and a fully dynamic equivalent load instantaneous removal method. First, the structure’s dynamic responses and collapse modes induced by different joints with different types of damage were explored. Subsequently, joint importance coefficients were proposed depending on the structure’s displacement before and after joint removal, and the relationships between the joint importance coefficients and the joint properties and collapse modes, respectively, were then identified. Finally, the relationship between the joint damage and the connected component damage was explored. The results revealed that different joints and identical joints with different types induced a variety of dynamic responses. However, the dynamic response induced by the discontinuous joint damage was more apparent than that induced by the continuous joint damage. When a continuous joint model was used, the damage on all joints did not result in the progressive or local progressive collapse of the structure. Thus, all these joints were considered as common joints. However, when a discontinuous joint model was used, the failure of the joints resulted in three distinct collapse modes, namely a progressive collapse, a local progressive collapse, and a nonprogressive collapse, corresponding to the key joints, the important joints, and the common joints, respectively. These three types of joints corresponded to different importance coefficients. When damage occurred in the discontinuous joints separately linked to the key components, the important components, and the common components, the joints resulted in the progressive collapse, local progressive collapse, and nonprogressive collapse, respectively, of the structure. Full article

Pulse–width modulated inverters are commonly used to control electrical drives, generating a common mode voltage and current with high–frequency components that excite the parasitic capacitances within electric machines, such as permanent magnet synchronous machines or induction machines. This results in different types of bearing currents that can shorten the service life of electric machines. One significant type of inverter–induced bearing currents are high–frequency circulating bearing currents. In this context, this work employs finite element analysis and time-domain simulations to determine the common mode current and circulating bearing current for various permanent magnet synchronous machine designs based on the traction machines of commercial electric vehicles with a focus on the stator. The results suggest that the ratio between the circulating bearing current and common mode current is much smaller in permanent magnet synchronous machines for traction applications than previously established in conventional induction machines, with values below 10% for all analyzed designs. A further increase in the robustness of such electric machines to the detrimental effects caused by the inverter supply could be achieved by reducing the parasitic winding–to–stator capacitance or by increasing the stator endwinding leakage inductance. Full article

A closed-form solution for the common and differential modal currents induced on a pair of infinitely long parallel conductors by a source, field coupled to a power line, is derived. For lossy conductors, the current consists of a continuous spectrum of radiation modes and (for the common mode) a modified low-loss Sommerfeld–Goubau (SG) mode and (for the differential mode) a quasi-TEM mode. This model is used to investigate the influence of a parallel conductor on microwave power line communication systems. When the complete current spectrum is used, it is shown that the SG mode is not the primary reason why low-loss communication is possible on power lines for distances on the order of 100 m. Nevertheless, and consistent with previous research, microwave communication using power lines has advantages over free space communication, and for typical parameters, the performance of these systems can be enhanced if the power line contains more than one conductor. Full article

Memory problems are common among older adults with a history of alcohol use disorder (AUD). Employing a machine learning framework, the current study investigates the use of multi-domain features to classify individuals with and without alcohol-induced memory problems. A group of 94 individuals (ages 50–81 years) with alcohol-induced memory problems (the memory group) were compared with a matched control group who did not have memory problems. The random forests model identified specific features from each domain that contributed to the classification of the memory group vs. the control group (AUC = 88.29%). Specifically, individuals from the memory group manifested a predominant pattern of hyperconnectivity across the default mode network regions except for some connections involving the anterior cingulate cortex, which were predominantly hypoconnected. Other significant contributing features were: (i) polygenic risk scores for AUD, (ii) alcohol consumption and related health consequences during the past five years, such as health problems, past negative experiences, withdrawal symptoms, and the largest number of drinks in a day during the past twelve months, and (iii) elevated neuroticism and increased harm avoidance, and fewer positive “uplift” life events. At the neural systems level, hyperconnectivity across the default mode network regions, including the connections across the hippocampal hub regions, in individuals with memory problems may indicate dysregulation in neural information processing. Overall, the study outlines the importance of utilizing multidomain features, consisting of resting-state brain connectivity data collected ~18 years ago, together with personality, life experiences, polygenic risk, and alcohol consumption and related consequences, to predict the alcohol-related memory problems that arise in later life. Full article

Switching operations in intelligent substations generate a wide range of extremely strong and asymmetric transient spatial electromagnetic fields, and this complex transient electromagnetic field can have a coupling effect with the wireless network sink node equipment cables. We conducted a study on the networking method of wireless network equipment in smart substations and analyzed the types of sink node cables used. In the GIS room of the 110 kV GIS smart substation, the transient spatial electromagnetic field generated by switching operation and the transient induced current of the sink node cable under different operating conditions were tested and obtained, and the time domain and frequency domain comparative analysis was performed. A near-field coupling model of the asymmetric and non-uniform cable transient spatial electric field at the sink node is established, and the validity of the model is verified by comparing and analyzing the measurement and simulation results. The results of the study can provide a reference for transient electromagnetic disturbances in 110 kV GIS intelligent substations and contribute to improving the reliability of wireless network equipment operation. Full article

The traditional route to achieving adequate structural performance in the event of fire is through ensuring that structural elements attain fire resistance ratings. The magnitude of these ratings typically varies in function of the building use, size, and height. In their genesis, fire resistance ratings were a proxy for the specification required of elements such that they had a reasonable likelihood of surviving the full duration of a fire, i.e., burn-out. As such, fire resistance periods were specified in the function of fire load, which, over time, progressively increased in consideration of the consequences of fire induced structural failure. This ratcheting of fire resistance periods was seemingly done so based on the collective experience of the profession, in response to observations from real fires and, where applicable, resulting disasters. That is, the safety levels associated with current fire resistance recommendations in most global codes and guidance documents are not determined. Therefore, this paper presents a review of reliability-based acceptance criteria for structures, ahead of their application, to determine fire resistance recommendations for buildings in England based on both codified reliability indices and the principle of relative (marginal) lifesaving costs. The study applies a novel form of probabilistic time equivalence, which is augmented by fire occurrence related statistics/parameters, to arrive at risk-informed fire resistance ratings that directly relate to the life safety consequences of fire induced structural failure (i.e., fatalities) to adequate fire resistance ratings. In determining these building fire resistance periods, it is observed that safety targets which implicitly include material damage and building reconstruction costs result in fire resistance recommendations that are well-aligned with National codes and standards. That is, to some extent, the ratcheting of fire resistance periods with time has resulted in some potential resilience to fire. Where safety targets are rationalised in consideration of life safety only, i.e., through the principle of relative (marginal) lifesaving costs, it is shown that fire resistance periods can be optimised, particularly in sprinkler protected buildings. However, this has the potential to introduce vulnerabilities to common mode failures. Full article