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26 pages, 9773 KiB  
Review
A Narrative Review of the Clinical Applications of Echocardiography in Right Heart Failure
by North J. Noelck, Heather A. Perry, Phyllis L. Talley and D. Elizabeth Le
J. Clin. Med. 2025, 14(15), 5505; https://doi.org/10.3390/jcm14155505 - 5 Aug 2025
Abstract
Background/Objectives: Historically, echocardiographic imaging of the right heart has been challenging because its abnormal geometry is not conducive to reproducible anatomical and functional assessment. With the development of advanced echocardiographic techniques, it is now possible to complete an integrated assessment of the right [...] Read more.
Background/Objectives: Historically, echocardiographic imaging of the right heart has been challenging because its abnormal geometry is not conducive to reproducible anatomical and functional assessment. With the development of advanced echocardiographic techniques, it is now possible to complete an integrated assessment of the right heart that has fewer assumptions, resulting in increased accuracy and precision. Echocardiography continues to be the first-line imaging modality for diagnostic analysis and the management of acute and chronic right heart failure because of its portability, versatility, and affordability compared to cardiac computed tomography, magnetic resonance imaging, nuclear scintigraphy, and positron emission tomography. Virtually all echocardiographic parameters have been well-validated and have demonstrated prognostic significance. The goal of this narrative review of the echocardiographic parameters of the right heart chambers and hemodynamic alterations associated with right ventricular dysfunction is to present information that must be acquired during each examination to deliver a comprehensive assessment of the right heart and to discuss their clinical significance in right heart failure. Methods: Using a literature search in the PubMed database from 1985 to 2025 and the Cochrane database, which included but was not limited to terminology that are descriptive of right heart anatomy and function, disease states involving acute and chronic right heart failure and pulmonary hypertension, and the application of conventional and advanced echocardiographic modalities that strive to elucidate the pathophysiology of right heart failure, we reviewed randomized control trials, observational retrospective and prospective cohort studies, societal guidelines, and systematic review articles. Conclusions: In addition to the conventional 2-dimensional echocardiography and color, spectral, and tissue Doppler measurements, a contemporary echocardiographic assessment of a patient with suspected or proven right heart failure must include 3-dimensional echocardiographic-derived measurements, speckle-tracking echocardiography strain analysis, and hemodynamics parameters to not only characterize the right heart anatomy but to also determine the underlying pathophysiology of right heart failure. Complete and point-of-care echocardiography is available in virtually all clinical settings for routine care, but this imaging tool is particularly indispensable in the emergency department, intensive care units, and operating room, where it can provide an immediate assessment of right ventricular function and associated hemodynamic changes to assist with real-time management decisions. Full article
(This article belongs to the Special Issue Cardiac Imaging in the Diagnosis and Management of Heart Failure)
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24 pages, 1414 KiB  
Review
Microplastics in Water Resources: Threats and Challenges
by Wojciech Strojny, Renata Gruca-Rokosz and Maksymilian Cieśla
Appl. Sci. 2025, 15(8), 4118; https://doi.org/10.3390/app15084118 - 9 Apr 2025
Viewed by 2119
Abstract
This study is a review of current knowledge on microplastics (MPs) in aquatic environments. In addition to identifying the sources of contamination by MPs in water and the hazards of their presence, an attempt is made to systematize the terminology of polymeric microparticles [...] Read more.
This study is a review of current knowledge on microplastics (MPs) in aquatic environments. In addition to identifying the sources of contamination by MPs in water and the hazards of their presence, an attempt is made to systematize the terminology of polymeric microparticles according to their size and to describe other parameters characteristic of MPs, i.e., shape and color. Special focus was placed on a review of the most important methods used to extract MPs from environmental matrices, as well as the latest and most effective analytical methods, highlighting their advantages and disadvantages. The value of the paper is in pointing out important developments in MPs analytics, identifying existing inaccuracies and limitations in the field and providing practical guidance. Thanks to its comprehensive approach, this article is a valuable resource for researchers concerned with the problem of environmental MPs pollution. Full article
(This article belongs to the Special Issue Pollution Control and Environmental Remediation)
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26 pages, 3804 KiB  
Review
Unveiling the Colors of Mustelids: A Historical Review on the Emergence of Chromatic Disorders and Their Ecological Effects in Mustelids Worldwide with Report of the First Case of Erythrism in Eira barbara (Carnivora, Mustelidae)
by Leonardo Cotts, Giovanna Costa, Sofia Isabel Gabriel, Oscar Rocha Barbosa and Caryne Braga
Animals 2024, 14(23), 3354; https://doi.org/10.3390/ani14233354 - 21 Nov 2024
Cited by 2 | Viewed by 2205
Abstract
Mustelidae is the largest and most diverse family within the order Carnivora, encompasses 65 species and 22 genera, and is widely distributed around the world. Mustelids exhibit a multiplicity of coloration patterns, ranging from darker tones, such as black and brown, to lighter [...] Read more.
Mustelidae is the largest and most diverse family within the order Carnivora, encompasses 65 species and 22 genera, and is widely distributed around the world. Mustelids exhibit a multiplicity of coloration patterns, ranging from darker tones, such as black and brown, to lighter tones, such as pale yellow and white. Anomalous colorations in wild mustelids are occasionally reported, but these records are still poorly discussed in the scientific literature and are often subject to misidentification and/or incorrect terminology. Among mustelids, the Tayra, Eira barbara, is suggested to have the highest frequency of chromatic disorders reported in the formal scientific literature, although most cases involve hypopigmentation. Here, we report and describe the first case of a reddish-colored tayra, a rare chromatic disorder known as erythrism, and compare their coloration to that observed in the subspecies currently suggested for E. barbara. We also conducted a survey and a review of chromatic variants in mustelids based on the formal scientific literature, reporting 119 anomalously colored individuals from 1890 to 2024, and proposed accurate terminology for misidentified cases. Additionally, we discuss the occurrence of these chromatic disorders on a global scale and their potential ecological effect on wild mustelids. Full article
(This article belongs to the Section Mammals)
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19 pages, 3236 KiB  
Review
A Closer Look at Heritage Systems from Medieval Colors to Modern and Contemporary Artworks
by Maria J. Melo, Márcia Vieira, Paula Nabais, Artur Neves, Marisa Pamplona and Eva Mariasole Angelin
Heritage 2024, 7(10), 5476-5494; https://doi.org/10.3390/heritage7100259 - 3 Oct 2024
Cited by 2 | Viewed by 3043
Abstract
This microreview, conducted by interdisciplinary teams, examines complex heritage material systems, such as medieval colors and modern and contemporary artworks. Our multi-analytical approach, a significant aspect of our research, is a means to this end. The conservation of works of art is our [...] Read more.
This microreview, conducted by interdisciplinary teams, examines complex heritage material systems, such as medieval colors and modern and contemporary artworks. Our multi-analytical approach, a significant aspect of our research, is a means to this end. The conservation of works of art is our shared goal, as it ensures their accessibility and the transfer of cultural heritage to future generations. We seek to interpret the damage, usefulness, and innovation of the experimental design in this context. As Jan Wouters rightly points out, “The terminology used nowadays to describe the potential damage to objects caused by analysis should be refined beyond the destructiveness/non-invasiveness polarization. A terminology should include at least degree level intervention (low, medium, high), usefulness, and innovation”. Complementing micro- or sub-micro-sampling with the appropriate analytical methods is crucial, as exemplified in medieval, modern, and contemporary collections studies. Finally, a novel perspective for exploring the information contained in the multiscale heterogeneity of organic historical materials is envisaged, and it includes UV/Visible photoluminescence spectral imaging using a low-intensity ultraviolet synchrotron beam. Full article
(This article belongs to the Special Issue Non-invasive Technologies Applied in Cultural Heritage)
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20 pages, 1694 KiB  
Article
Centering Women of Color: Chronic Vulvovaginal Pain (CVVP) Communication
by Olivia R. Adams, Amanda N. Gesselman and Margaret Bennett-Brown
Soc. Sci. 2024, 13(5), 265; https://doi.org/10.3390/socsci13050265 - 15 May 2024
Cited by 1 | Viewed by 2278
Abstract
Background: Black and white women describe their chronic vulvar pain (CVVP) symptoms differently, indicating a patient–provider communication deficit. This may contribute to the diagnostic delay commonly reported by patients with CVVP and/or pelvic pain. Methods: A pilot study demonstrated CVVP terminology differences between [...] Read more.
Background: Black and white women describe their chronic vulvar pain (CVVP) symptoms differently, indicating a patient–provider communication deficit. This may contribute to the diagnostic delay commonly reported by patients with CVVP and/or pelvic pain. Methods: A pilot study demonstrated CVVP terminology differences between women of color and white women. The present study (N = 488) includes a sample of predominantly cisgender women who identified their race/ethnicity as Black, Hispanic/Latinx, Native American/American Indian, and/or Asian. Participants reported how they describe their CVVP, their healthcare experiences, and characteristics of their diagnostic journey. Results: Descriptions of CVVP were not uniform. Instead, there was great variability in how women described their pain across racial/ethnic identities and pain contexts (e.g., sexual activity, menstrual product use, and pelvic exam). Some pain experiences and descriptors were associated with healthcare outcomes related to diagnostic delay. Conclusions: This study sheds light on the pain communication experiences of women of color with CVVP, an understudied population within the broader CVVP literature. By resisting white and non-white comparative methodologies, this study demonstrates the applicability of intersectionality principles to the study of CVVP and contributes to the existing literature regarding pain communication, race, and ethnicity. Full article
(This article belongs to the Special Issue Chronic Health Conditions and Bodies: Methods, Meanings, and Medicine)
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19 pages, 11765 KiB  
Article
An Unknown 18th-Century Flemish Dyers Manuscript from Antwerp (1778–1802)
by Emile Lupatini and Natalia Ortega Saez
Heritage 2024, 7(5), 2458-2476; https://doi.org/10.3390/heritage7050117 - 9 May 2024
Cited by 2 | Viewed by 2686
Abstract
This paper presents a historical analysis of a rare dyer’s manuscript, preserved within the Museum of Industry in Ghent, Belgium. The manuscript, originating from a dyer in late 18th-century Antwerp, includes an extensive collection of recipes. The study will enable researchers to better [...] Read more.
This paper presents a historical analysis of a rare dyer’s manuscript, preserved within the Museum of Industry in Ghent, Belgium. The manuscript, originating from a dyer in late 18th-century Antwerp, includes an extensive collection of recipes. The study will enable researchers to better grasp the practices of traditional dyeing techniques and materials in the region during that time. The manuscript focuses primarily on the dyeing of woolen fabrics. Approximately 90 of the 132 recipes utilize red dyes. Recipes for dying orange, brown, black, blue, and green colors are also described. The document mentions the use of madder, brazilwood, redwood, and cochineal. To create a variety of red shades, the dyer describes how fabrics were treated with different mordanting compounds, with alum and tin as the main ingredients, and how the dyeing solutions were prepared. The resulting colors include ‘madder red’, ‘formal red’, ‘crimson’, ‘scarlet’, ‘Turkish red’, ‘fire color’ and ‘flesh color’. In addition to the dyeing recipes, the manuscript contains various accounting documents and correspondences between the dyer, customers, and suppliers. Lastly, over 100 original, colored samples are attached to the described recipes. In this paper, the artifact’s contents will be disclosed, comprising recipes with attached samples and correspondence. Findings resulting from archive research will be included, contextualizing and placing the dyer in their urban and social context. The paper concludes by discussing its potential limitations and provides avenues for possible future research. Full article
(This article belongs to the Special Issue Dyes in History and Archaeology 42)
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21 pages, 972 KiB  
Review
Smartphone-Based Color Evaluation of Passive Samplers for Gases: A Review
by Kanokwan Kiwfo, Kate Grudpan, Andreas Held and Wolfgang Frenzel
Atmosphere 2024, 15(4), 451; https://doi.org/10.3390/atmos15040451 - 4 Apr 2024
Cited by 2 | Viewed by 2700
Abstract
The application of smartphone-based color evaluation of passive sampling devices for gases has only been sparsely reported. The present review aims to compile available publications with respect to the configuration of the passive samplers, conditions of smartphone photographing, analytical procedures for color detection [...] Read more.
The application of smartphone-based color evaluation of passive sampling devices for gases has only been sparsely reported. The present review aims to compile available publications with respect to the configuration of the passive samplers, conditions of smartphone photographing, analytical procedures for color detection and quantification (including calibration processes), and their application to different target gases. The performance of the methods—whenever available—is presented regarding the analytical specifications selectivity, sensitivity, and limit of detection in comparison with other color evaluation methods of passive samplers. Practical aspects like requirements of instrumentation and ease of use will be outlined in view of the potential employment in education and citizen science projects. In one section of the review, the inconsistent terminology of passive and diffusive sampling is discussed in order to clarify the distinction of information obtained from the uptake of the passive samplers between gas-phase concentration and the accumulated deposition flux of gaseous analytes. Colorimetric gas sensors are included in the review when applied in passive sampling configurations and evaluation is performed with smartphone-based color evaluation. Differences in the analytical procedures employed after the passive sampling step and prior to the detection of the colored compounds are also presented. Full article
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13 pages, 3018 KiB  
Article
Remote Moderated Usability Testing of a Mobile Phone App for Remote Monitoring of Pregnant Women at High Risk of Preeclampsia in Karachi, Pakistan
by Anam Shahil-Feroz, Haleema Yasmin, Sarah Saleem, Zulfiqar Bhutta and Emily Seto
Informatics 2023, 10(4), 79; https://doi.org/10.3390/informatics10040079 - 17 Oct 2023
Cited by 3 | Viewed by 3069
Abstract
This study assessed the usability of the smartphone app, named “Raabta” from the perspective of pregnant women at high risk of preeclampsia to improve the Raabta app for future implementation. Think-aloud and task-completion techniques were used with a purposive sample of [...] Read more.
This study assessed the usability of the smartphone app, named “Raabta” from the perspective of pregnant women at high risk of preeclampsia to improve the Raabta app for future implementation. Think-aloud and task-completion techniques were used with a purposive sample of 14 pregnant women at high risk of preeclampsia. The sessions were audio-recorded and later professionally transcribed for thematic analysis. The study generated learnings associated with four themes: improving the clarity of instructions, messaging, and terminology; accessibility for non-tech savvy and illiterate Urdu users; enhancing visuals and icons for user engagement; and simplifying navigation and functionality. Overall, user feedback emphasized the importance of enhancing the clarity of instructions, messaging, and terminology within the Raabta app. Voice messages and visuals were valued by users, particularly among the non-tech savvy and illiterate Urdu users, as they enhance accessibility and enable independent monitoring. Suggestions were made to enhance user engagement through visual improvements such as enhanced graphics and culturally aligned color schemes. Lastly, users highlighted the need for improved navigation both between screens and within screens to enhance the overall user experience. The Raabta app prototype will be modified based on the feedback of the users to address the unique needs of diverse groups. Full article
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23 pages, 20552 KiB  
Article
ABANICCO: A New Color Space for Multi-Label Pixel Classification and Color Analysis
by Laura Nicolás-Sáenz, Agapito Ledezma, Javier Pascau and Arrate Muñoz-Barrutia
Sensors 2023, 23(6), 3338; https://doi.org/10.3390/s23063338 - 22 Mar 2023
Cited by 5 | Viewed by 4005
Abstract
Classifying pixels according to color, and segmenting the respective areas, are necessary steps in any computer vision task that involves color images. The gap between human color perception, linguistic color terminology, and digital representation are the main challenges for developing methods that properly [...] Read more.
Classifying pixels according to color, and segmenting the respective areas, are necessary steps in any computer vision task that involves color images. The gap between human color perception, linguistic color terminology, and digital representation are the main challenges for developing methods that properly classify pixels based on color. To address these challenges, we propose a novel method combining geometric analysis, color theory, fuzzy color theory, and multi-label systems for the automatic classification of pixels into 12 conventional color categories, and the subsequent accurate description of each of the detected colors. This method presents a robust, unsupervised, and unbiased strategy for color naming, based on statistics and color theory. The proposed model, “ABANICCO” (AB ANgular Illustrative Classification of COlor), was evaluated through different experiments: its color detection, classification, and naming performance were assessed against the standardized ISCC–NBS color system; its usefulness for image segmentation was tested against state-of-the-art methods. This empirical evaluation provided evidence of ABANICCO’s accuracy in color analysis, showing how our proposed model offers a standardized, reliable, and understandable alternative for color naming that is recognizable by both humans and machines. Hence, ABANICCO can serve as a foundation for successfully addressing a myriad of challenges in various areas of computer vision, such as region characterization, histopathology analysis, fire detection, product quality prediction, object description, and hyperspectral imaging. Full article
(This article belongs to the Special Issue Recent Trends and Advances in Color and Spectral Sensors)
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19 pages, 4116 KiB  
Review
On the Importance of the Starting Material Choice and Analytical Procedures Adopted When Developing a Strategy for the Nanoencapsulation of Saffron (Crocus sativus L.) Bioactive Antioxidants
by Maria Z. Tsimidou
Antioxidants 2023, 12(2), 496; https://doi.org/10.3390/antiox12020496 - 16 Feb 2023
Cited by 4 | Viewed by 2985
Abstract
Saffron is known as the most expensive spice in the world. It is comprised of the dried stigmas of the pistil of the Crocus sativus L., which is a cultivated, sterile crocus plant. This plant material is now recognized as the unique edible [...] Read more.
Saffron is known as the most expensive spice in the world. It is comprised of the dried stigmas of the pistil of the Crocus sativus L., which is a cultivated, sterile crocus plant. This plant material is now recognized as the unique edible source of certain bioactive apocarotenoids for which in-vivo antioxidant properties have been reported. Among the latter, crocins, red-orange natural colorants, and their parent molecule crocetin prevail in bioactivity significance. This review is focused on the strategies developed so far for their nanoencapsulation in relation to the characteristics of the starting material, extraction procedures of the bioactive antioxidants and analytical methods applied for their characterization and quantification throughout the process. The literature so far points out gaps that lead to publishable data, on one hand, but not necessarily to repeatable and meaningful processes due to incomplete characterization of the starting and the released material in efficiency and stability studies of the nanoencapsulates. Accurate terminology and quantitative chromatographic or spectrophotometric procedures for the determination of the core compounds are needed. Authenticity control and quality of saffron samples, and the verification of the concentrations of compounds in commercial preparations labeled as ‘crocin,’ are prerequisites in any experimental design setup. Full article
(This article belongs to the Special Issue Nanoantioxidants Volume II)
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15 pages, 2779 KiB  
Article
Sensory Wheel and Lexicon for the Description of Cold-Pressed Hemp Seed Oil
by Matilde Tura, Mara Mandrioli, Enrico Valli, Caterina Dinnella and Tullia Gallina Toschi
Foods 2023, 12(3), 661; https://doi.org/10.3390/foods12030661 - 3 Feb 2023
Cited by 9 | Viewed by 4062
Abstract
Cold-pressed hemp seed oil (CP-HSO) has become available on the market and is gaining popularity mainly for its appeal and nutritional profile. The sensory quality largely depends on seed quality and processing as well as oil storage conditions. Given the “native” nature of [...] Read more.
Cold-pressed hemp seed oil (CP-HSO) has become available on the market and is gaining popularity mainly for its appeal and nutritional profile. The sensory quality largely depends on seed quality and processing as well as oil storage conditions. Given the “native” nature of the product, obtained by cold-pressing, the development of a standardized methodology to evaluate and describe the sensory quality of HSOs is of the utmost importance. To this aim, 16 commercial HSOs were evaluated, covering the main differences in brands and sales channels. A trained panel developed a vocabulary to describe the HSO profile consisting of 44 attributes, and a practical sensory wheel was proposed to classify attributes in different clusters and according to sensory modality. A sensory profile sheet was developed including two color descriptors (yellow, green), seven main positive (sunflower/pumpkin seeds, nutty, toasted nutty, hay, sweet, bitter, and pungent), several secondary positive (herbs, coffee, tobacco, etc.), four main defects (rancid, paint, burnt, and fish), and other secondary negative descriptors (boiled vegetables, cucumber, etc.). Subsequently, specific training of the panelists was carried out, and a satisfactory performance level was reached. This study represents the first attempt to standardize the sensory quality and terminology of HSO. Full article
(This article belongs to the Special Issue Food Flavor Chemistry and Sensory Evaluation)
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18 pages, 5154 KiB  
Article
Conditional Generative Adversarial Networks with Total Variation and Color Correction for Generating Indonesian Face Photo from Sketch
by Mia Rizkinia, Nathaniel Faustine and Masahiro Okuda
Appl. Sci. 2022, 12(19), 10006; https://doi.org/10.3390/app121910006 - 5 Oct 2022
Cited by 8 | Viewed by 3824
Abstract
Historically, hand-drawn face sketches have been commonly used by Indonesia’s police force, especially to quickly describe a person’s facial features in searching for fugitives based on eyewitness testimony. Several studies have been performed, aiming to increase the effectiveness of the method, such as [...] Read more.
Historically, hand-drawn face sketches have been commonly used by Indonesia’s police force, especially to quickly describe a person’s facial features in searching for fugitives based on eyewitness testimony. Several studies have been performed, aiming to increase the effectiveness of the method, such as comparing the facial sketch with the all-points bulletin (DPO in Indonesian terminology) or generating a facial composite. However, making facial composites using an application takes quite a long time. Moreover, when these composites are directly compared to the DPO, the accuracy is insufficient, and thus, the technique requires further development. This study applies a conditional generative adversarial network (cGAN) to convert a face sketch image into a color face photo with an additional Total Variation (TV) term in the loss function to improve the visual quality of the resulting image. Furthermore, we apply a color correction to adjust the resulting skin tone similar to that of the ground truth. The face image dataset was collected from various sources matching Indonesian skin tone and facial features. We aim to provide a method for Indonesian face sketch-to-photo generation to visualize the facial features more accurately than the conventional method. This approach produces visually realistic photos from face sketches, as well as true skin tones. Full article
(This article belongs to the Special Issue Recent Advances in Deep Learning for Image Analysis)
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46 pages, 10022 KiB  
Systematic Review
A Systematic Review for Establishing Relevant Environmental Parameters for Urban Lighting: Translating Research into Practice
by Catherine Pérez Vega, Karolina M. Zielinska-Dabkowska, Sibylle Schroer, Andreas Jechow and Franz Hölker
Sustainability 2022, 14(3), 1107; https://doi.org/10.3390/su14031107 - 19 Jan 2022
Cited by 33 | Viewed by 10543 | Correction
Abstract
The application of lighting technologies developed in the 20th century has increased the brightness and changed the spectral composition of nocturnal night-time habitats and night skies across urban, peri-urban, rural, and pristine landscapes, and subsequently, researchers have observed the disturbance of biological rhythms [...] Read more.
The application of lighting technologies developed in the 20th century has increased the brightness and changed the spectral composition of nocturnal night-time habitats and night skies across urban, peri-urban, rural, and pristine landscapes, and subsequently, researchers have observed the disturbance of biological rhythms of flora and fauna. To reduce these impacts, it is essential to translate relevant knowledge about the potential adverse effects of artificial light at night (ALAN) from research into applicable urban lighting practice. Therefore, the aim of this paper is to identify and report, via a systematic review, the effects of exposure to different physical properties of artificial light sources on various organism groups, including plants, arthropods, insects, spiders, fish, amphibians, reptiles, birds, and non-human mammals (including bats, rodents, and primates). PRISMA 2020 guidelines were used to identify a total of 1417 studies from Web of Science and PubMed. In 216 studies, diverse behavioral and physiological responses were observed across taxa when organisms were exposed to ALAN. The studies showed that the responses were dependent on high illuminance levels, duration of light exposure, and unnatural color spectra at night and also highlighted where research gaps remain in the domains of ALAN research and urban lighting practice. To avoid misinterpretation, and to define a common language, key terminologies and definitions connected to natural and artificial light have been provided. Furthermore, the adverse impacts of ALAN urgently need to be better researched, understood, and managed for the development of future lighting guidelines and standards to optimize sustainable design applications that preserve night-time environment(s) and their inhabiting flora and fauna. Full article
(This article belongs to the Section Sustainable Engineering and Science)
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26 pages, 2751 KiB  
Review
Forensic Facial Comparison: Current Status, Limitations, and Future Directions
by Nicholas Bacci, Joshua G. Davimes, Maryna Steyn and Nanette Briers
Biology 2021, 10(12), 1269; https://doi.org/10.3390/biology10121269 - 3 Dec 2021
Cited by 14 | Viewed by 9143
Abstract
Global escalation of crime has necessitated the use of digital imagery to aid the identification of perpetrators. Forensic facial comparison (FFC) is increasingly employed, often relying on poor-quality images. In the absence of standardized criteria, especially in terms of video recordings, verification of [...] Read more.
Global escalation of crime has necessitated the use of digital imagery to aid the identification of perpetrators. Forensic facial comparison (FFC) is increasingly employed, often relying on poor-quality images. In the absence of standardized criteria, especially in terms of video recordings, verification of the methodology is needed. This paper addresses aspects of FFC, discussing relevant terminology, investigating the validity and reliability of the FISWG morphological feature list using a new South African database, and advising on standards for CCTV equipment. Suboptimal conditions, including poor resolution, unfavorable angle of incidence, color, and lighting, affected the accuracy of FFC. Morphological analysis of photographs, standard CCTV, and eye-level CCTV showed improved performance in a strict iteration analysis, but not when using analogue CCTV images. Therefore, both strict and lenient iterations should be conducted, but FFC must be abandoned when a strict iteration performs worse than a lenient one. This threshold ought to be applied to the specific CCTV equipment to determine its utility. Chance-corrected accuracy was the most representative measure of accuracy, as opposed to the commonly used hit rate. While the use of automated systems is increasing, trained human observer-based morphological analysis, using the FISWG feature list and an Analysis, Comparison, Evaluation, and Verification (ACE-V) approach, should be the primary method of facial comparison. Full article
(This article belongs to the Special Issue Recent Advances in Forensic Anthropological Methods and Research)
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16 pages, 3500 KiB  
Article
Objective Evaluation of Risk Factors for Radiation Dermatitis in Whole-Breast Irradiation Using the Spectrophotometric L*a*b Color-Space
by Alexander M. C. Böhner, David Koch, Frederic Carsten Schmeel, Fred Röhner, Felix Schoroth, Gustavo R. Sarria, Alina-Valik Abramian, Brigitta Gertrud Baumert, Frank Anton Giordano and Leonard Christopher Schmeel
Cancers 2020, 12(9), 2444; https://doi.org/10.3390/cancers12092444 - 28 Aug 2020
Cited by 28 | Viewed by 5270
Abstract
Background: Radiation-induced dermatitis (RID) is frequent in breast cancer patients undergoing radiotherapy (RT). Spectrophotometry (SP) is an objective and reliable tool for assessing RID severity. Despite intensive research efforts during the past decades, no sustainable prophylactic and treatment strategies have been found. [...] Read more.
Background: Radiation-induced dermatitis (RID) is frequent in breast cancer patients undergoing radiotherapy (RT). Spectrophotometry (SP) is an objective and reliable tool for assessing RID severity. Despite intensive research efforts during the past decades, no sustainable prophylactic and treatment strategies have been found. Estimation of new and reevaluation of established risk factors leading to severe RID is therefore of major importance. Methods: 142 early breast cancer patients underwent whole-breast irradiation following breast-conserving surgery. RID was evaluated by physician-assessed Common Terminology Criteria of Adverse Events (CTCAE v4.03). Spectrophotometers provided additional semi quantification of RID using the L*a*b color-space. A total of 24 patient- and treatment-related parameters as well as subjective patient-assessed symptoms were analyzed. Results: Values for a*max strongly correlated with the assessment of RID severity by physicians. Breast volume, initial darker skin, boost administration, and treatment technique were identified as risk factors for severe RID. RID severity positively correlated with the patients’ perception of pain, burning, and reduction of everyday activities. Conclusions: Physician-assessed RID gradings correlate with objective SP skin measurements. Treatment technique and high breast volumes were identified as objective and significant predictors of RID. Our data provide a solid benchmark for future studies on RID with objective SP. Full article
(This article belongs to the Section Cancer Survivorship and Quality of Life)
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