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64 Results Found

  • Article
  • Open Access
2 Citations
2,900 Views
16 Pages

26 December 2023

An unmanned aerial vehicle (UAV) swarm is a fast-moving system where self-adaption is necessary when conducting a mission. The major causative factors of mission failures are inevitable disruptive events and uncertain threats. Given the unexpected di...

  • Article
  • Open Access
4,308 Views
31 Pages

The Consequences of a Disruption in Cyto-Nuclear Coadaptation on the Molecular Response to a Nitrate Starvation in Arabidopsis

  • Fabien Chardon,
  • Gwendal Cueff,
  • Etienne Delannoy,
  • Fabien Aubé,
  • Aurélia Lornac,
  • Magali Bedu,
  • Françoise Gilard,
  • Stéphanie Pateyron,
  • Hélène Rogniaux and
  • Françoise Budar
  • + 4 authors

1 May 2020

Mitochondria and chloroplasts are important actors in the plant nutritional efficiency. So, it could be expected that a disruption of the coadaptation between nuclear and organellar genomes impact plant response to nutrient stresses. We addressed thi...

  • Article
  • Open Access
18 Citations
5,071 Views
14 Pages

13 May 2019

Conventional myoelectric controllers provide a mapping between electromyographic signals and prosthetic functions. However, due to a number of instabilities continuously challenging this process, an initial mapping may require an extended calibration...

  • Review
  • Open Access
2 Citations
6,186 Views
33 Pages

22 October 2025

Neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), present a growing public health challenge globally. Recent advancements in neurotechnology and neuroengineering have significantly enhanced brain...

  • Review
  • Open Access
341 Citations
35,447 Views
75 Pages

Fluctuating Asymmetry: Methods, Theory, and Applications

  • John H. Graham,
  • Shmuel Raz,
  • Hagit Hel-Or and
  • Eviatar Nevo

25 March 2010

Fluctuating asymmetry consists of random deviations from perfect symmetry in populations of organisms. It is a measure of developmental noise, which reflects a population’s average state of adaptation and coadaptation. Moreover, it increases under bo...

  • Article
  • Open Access
2 Citations
1,939 Views
19 Pages

Co-Adapting a Reflective Video-Based Professional Development in Informal STEM Education

  • Amber Simpson,
  • Alice Anderson,
  • Adam V. Maltese,
  • Lauren Penney and
  • Kelli Paul

12 March 2025

Traditional professional development for informal educators often relies on brief, lecture-based sessions that reinforce familiar teaching practices. In collaboration with 27 informal learning organizations across four years, we attended to the need...

  • Article
  • Open Access
12 Citations
3,172 Views
19 Pages

A Method for In Situ Reverse Genetic Analysis of Proteins Involved mtDNA Replication

  • Natalya Kozhukhar,
  • Domenico Spadafora,
  • Yelitza A. R. Rodriguez and
  • Mikhail F. Alexeyev

11 July 2022

The unavailability of tractable reverse genetic analysis approaches represents an obstacle to a better understanding of mitochondrial DNA replication. Here, we used CRISPR-Cas9 mediated gene editing to establish the conditional viability of knockouts...

  • Article
  • Open Access
24 Citations
10,140 Views
26 Pages

Metacognition as a Consequence of Competing Evolutionary Time Scales

  • Franz Kuchling,
  • Chris Fields and
  • Michael Levin

26 April 2022

Evolution is full of coevolving systems characterized by complex spatio-temporal interactions that lead to intertwined processes of adaptation. Yet, how adaptation across multiple levels of temporal scales and biological complexity is achieved remain...

  • Article
  • Open Access
409 Views
23 Pages

Improving absolute accuracy in industrial manipulators remains difficult because rigid-body kinematic calibration cannot fully represent configuration-dependent non-geometric effects. Drawing inspiration from biological brain–body co-adaptation...

  • Article
  • Open Access
5 Citations
5,734 Views
25 Pages

Sustainable Use of the Littoral by Traditional People of Barbados and Bahamas

  • Brent Stoffle,
  • Richard Stoffle and
  • Kathleen Van Vlack

11 June 2020

This paper is about the traditional people of Barbados and The Bahamas, in the Caribbean and their sustainable adaptations to the littoral, which included both marine and terrestrial components. Traditional people are defined as having lived in a sus...

  • Feature Paper
  • Review
  • Open Access
50 Citations
17,683 Views
21 Pages

Myoelectric Control for Upper Limb Prostheses

  • Carles Igual,
  • Luis A. Pardo,
  • Janne M. Hahne and
  • Jorge Igual

30 October 2019

State-of-the-art high-end prostheses are electro-mechanically able to provide a great variety of movements. Nevertheless, in order to functionally replace a human limb, it is essential that each movement is properly controlled. This is the goal of pr...

  • Review
  • Open Access
1 Citations
1,176 Views
35 Pages

Upper-limb motor impairment is a major consequence of stroke and neuromuscular disorders, imposing a sustained clinical and socioeconomic burden worldwide. Quantitative assessment of limb positioning and motion accuracy is fundamental to rehabilitati...

  • Communication
  • Open Access
4 Citations
2,487 Views
9 Pages

Carbon Monoxide (CO) as a Retinal Regulator of Heme Oxygenases -1, and -2 (HO’s) Expression

  • Sławomir Nowak,
  • Przemysław Gilun,
  • Katarzyna Kozioł,
  • Maria Romerowicz-Misielak,
  • Magdalena Koziorowska-Gilun and
  • Barbara Wąsowska

Carbon monoxide (CO) has been proposed as a chemical light signal and neural system modulator via heme oxygenases -1 and -2 (HO-1 and HO-2). Many papers have proven the CO-HO circuit to be important for such physiological pathways as the molecular bi...

  • Review
  • Open Access
50 Citations
5,420 Views
18 Pages

10 April 2020

Due to the endosymbiotic origin of organelles, a pattern of coevolution and coadaptation between organellar and nuclear genomes is required for proper cell function. In this review, we focus on the impact of cytonuclear interaction on the reproductiv...

  • Review
  • Open Access
34 Citations
12,766 Views
19 Pages

24 May 2021

The functions of the female reproductive tract not only encompass sperm migration, storage, and fertilization, but also support the transport and development of the fertilized egg through to the birth of offspring. Further, because the tract is open...

  • Review
  • Open Access
128 Citations
30,299 Views
28 Pages

16 February 2023

Our skin is the largest organ of the body, serving as an important barrier against the harsh extrinsic environment. Alongside preventing desiccation, chemical damage and hypothermia, this barrier protects the body from invading pathogens through a so...

  • Article
  • Open Access
22 Citations
6,696 Views
17 Pages

Different Metabolic Pathways Are Involved in Response of Saccharomyces cerevisiae to L-A and M Viruses

  • Juliana Lukša,
  • Bazilė Ravoitytė,
  • Aleksandras Konovalovas,
  • Lina Aitmanaitė,
  • Anzhelika Butenko,
  • Vyacheslav Yurchenko,
  • Saulius Serva and
  • Elena Servienė

25 July 2017

Competitive and naturally occurring yeast killer phenotype is governed by coinfection with dsRNA viruses. Long-term relationship between the host cell and viruses appear to be beneficial and co-adaptive; however, the impact of viral dsRNA on the host...

  • Article
  • Open Access
1 Citations
1,121 Views
22 Pages

11 August 2025

With the large-scale integration of renewable energy through power electronic inverters,

modern power systems are gradually transitioning to low-inertia systems. Grid-forming

inverters are prone to power overshoot and frequency deviation when facing ex...

  • Article
  • Open Access
455 Views
17 Pages

12 January 2026

This study reports the first complete mitochondrial genome of the traditional medicinal and edible crop, D. opposita (493,268 bp, 45.67% GC). We annotated 39 unique protein-coding genes (PCGs), which included 24 core mitochondrial genes and 15 variab...

  • Brief Report
  • Open Access
1 Citations
396 Views
11 Pages

16 January 2026

Monitoring epibiotic communities on the invasive red king crab (Paralithodes camtschaticus) in the Barents Sea is crucial for understanding the co-adaptation between this species and the local benthic fauna. Red king crabs were collected during regul...

  • Review
  • Open Access
3 Citations
4,582 Views
24 Pages

Investigating the Impact of a Curse: Diseases, Population Isolation, Evolution and the Mother’s Curse

  • Maria-Anna Kyrgiafini,
  • Themistoklis Giannoulis,
  • Katerina A. Moutou and
  • Zissis Mamuris

18 November 2022

The mitochondrion was characterized for years as the energy factory of the cell, but now its role in many more cellular processes is recognized. The mitochondrion and mitochondrial DNA (mtDNA) also possess a set of distinct properties, including mate...

  • Review
  • Open Access
17 Citations
3,761 Views
17 Pages

20 April 2022

Hybrid rye breeding leads to considerably higher grain yield and a higher revenue to the farmer. The basis of hybrid seed production is the CMS-inducing Pampa (P) cytoplasm derived from an Argentinean landrace and restorer-to-fertility (Rf) genes. Eu...

  • Perspective
  • Open Access
16 Citations
5,320 Views
12 Pages

Healthy Teleworking: Towards Personalized Exercise Recommendations

  • Maricarmen Almarcha,
  • Natàlia Balagué and
  • Carlota Torrents

15 March 2021

Home-based teleworking, associated with sedentary behavior, may impair self-reported adult health status. Current exercise recommendations, based on universal recipes, may be insufficient or even misleading to promote healthy teleworking. From the Ne...

  • Article
  • Open Access
13 Citations
3,325 Views
24 Pages

Genetic Control of Reproductive Traits under Different Temperature Regimes in Inbred Line Populations Derived from Crosses between S. pimpinellifolium and S. lycopersicum Accessions

  • Maria Jose Gonzalo,
  • Luciano Carlos da Maia,
  • Inmaculada Nájera,
  • Carlos Baixauli,
  • Giovanni Giuliano,
  • Paola Ferrante,
  • Antonio Granell,
  • Maria Jose Asins and
  • Antonio Jose Monforte

14 April 2022

In the present work, we study the genetic control of reproductive traits under different heat stress conditions in two populations of inbred lines derived from crosses between two S. pimpinellifolium accessions and two tomato cultivars (E9×L5 a...

  • Article
  • Open Access
503 Views
19 Pages

9 March 2026

Motor imagery EEG decoding often relies on static functional connectivity graphs that cannot capture the dynamic, stage-wise reorganization of brain networks during tasks. This paper aims to develop a graph neural network that explicitly simulates th...

  • Article
  • Open Access
16 Citations
3,230 Views
15 Pages

21 April 2020

Due to the large size of the heavy duty machine tool-foundation systems, space temperature difference is high related to thermal error, which affects to system’s accuracy greatly. The recent highly focused deep learning technology could be an a...

  • Article
  • Open Access
15 Citations
4,968 Views
16 Pages

Olfactory Learning in the Stingless Bee Melipona eburnea Friese (Apidae: Meliponini)

  • Marisol Amaya-Márquez,
  • Sergio Tusso,
  • Juan Hernández,
  • Juan Darío Jiménez,
  • Harrington Wells and
  • Charles I. Abramson

18 November 2019

Olfactory learning and floral scents are co-adaptive traits in the plant–pollinator relationship. However, how scent relates to cognition and learning in the diverse group of Neotropical stingless bees is largely unknown. Here we evaluated the...

  • Article
  • Open Access
2 Citations
1,548 Views
20 Pages

Deep Learning Strategies for Semantic Segmentation in Robot-Assisted Radical Prostatectomy

  • Elena Sibilano,
  • Claudia Delprete,
  • Pietro Maria Marvulli,
  • Antonio Brunetti,
  • Francescomaria Marino,
  • Giuseppe Lucarelli,
  • Michele Battaglia and
  • Vitoantonio Bevilacqua

2 October 2025

Robot-assisted radical prostatectomy (RARP) has become the most prevalent treatment for patients with organ-confined prostate cancer. Despite superior outcomes, suboptimal vesicourethral anastomosis (VUA) may lead to serious complications, including...

  • Review
  • Open Access
107 Citations
11,293 Views
28 Pages

Liquid Biomolecular Condensates and Viral Lifecycles: Review and Perspectives

  • Temitope Akhigbe Etibor,
  • Yohei Yamauchi and
  • Maria João Amorim

25 February 2021

Viruses are highly dependent on the host they infect. Their dependence triggers processes of virus–host co-adaptation, enabling viruses to explore host resources whilst escaping immunity. Scientists have tackled viral–host interplay at differing leve...

  • Review
  • Open Access
89 Citations
19,894 Views
36 Pages

16 December 2016

Fluctuating asymmetry, the random deviation from perfect symmetry, is a widely used population-level index of developmental instability, developmental noise, and robustness. It reflects a population’s state of adaptation and genomic coadaptation. Her...

  • Article
  • Open Access
1,326 Views
21 Pages

30 May 2024

Over the years, alien chromosome substitution has attracted the attention of geneticists and breeders as a rich source of remarkable genetic diversity for improvement in narrowly adapted wheat cultivars. One of the problems encountered along this way...

  • Article
  • Open Access
1 Citations
1,535 Views
16 Pages

Unique Structural Features Relate to Evolutionary Adaptation of Cytochrome P450 in the Abyssal Zone

  • Tatiana Y. Hargrove,
  • David C. Lamb,
  • Zdzislaw Wawrzak,
  • George Minasov,
  • Jared V. Goldstone,
  • Steven L. Kelly,
  • John J. Stegeman and
  • Galina I. Lepesheva

Cytochromes P450 (CYPs) form one of the largest enzyme superfamilies, with similar structural folds yet biological functions varying from synthesis of physiologically essential compounds to metabolism of myriad xenobiotics. Sterol 14α-demethyla...

  • Article
  • Open Access
314 Views
23 Pages

13 February 2026

Surface defect detection in aluminum-based composite core conductors (ACCC) via X-ray imaging has long been constrained by challenges such as small sample sizes, class imbalance, model redundancy, and inadequate adaptation to single-channel industria...

  • Article
  • Open Access
3 Citations
1,977 Views
18 Pages

14 September 2024

Eco-spatial indices are commonly used tools to improve the quality of the environment in cities. Initially modelled on the Berlin BAF, indices have evolved to address current challenges, particularly climate change adaptation. The Ratio of Biological...

  • Article
  • Open Access
22 Citations
4,400 Views
17 Pages

Genomic Analysis of Vavilov’s Historic Chickpea Landraces Reveals Footprints of Environmental and Human Selection

  • Alena Sokolkova,
  • Sergey V. Bulyntsev,
  • Peter L. Chang,
  • Noelia Carrasquilla-Garcia,
  • Anna A. Igolkina,
  • Nina V. Noujdina,
  • Eric von Wettberg,
  • Margarita A. Vishnyakova,
  • Douglas R. Cook and
  • Maria G. Samsonova
  • + 1 author

A defining challenge of the 21st century is meeting the nutritional demands of the growing human population, under a scenario of limited land and water resources and under the specter of climate change. The Vavilov seed bank contains numerous landrac...

  • Review
  • Open Access
10 Citations
6,425 Views
25 Pages

Mono a Mano: ZBP1’s Love–Hate Relationship with the Kissing Virus

  • Alan Herbert,
  • Aleksandr Fedorov and
  • Maria Poptsova

Z-DNA binding protein (ZBP1) very much represents the nuclear option. By initiating inflammatory cell death (ICD), ZBP1 activates host defenses to destroy infectious threats. ZBP1 is also able to induce noninflammatory regulated cell death via apopto...

  • Article
  • Open Access
1,827 Views
18 Pages

Altitudinal Gradient Drives Rhizosphere Microbial Structure and Functional Potential in Prickly Pear Cactus (Opuntia ficus-indica L.)

  • Lorena Jacqueline Gómez-Godínez,
  • José Luis Aguirre-Noyola,
  • Carlos Hugo Avendaño-Arrazate,
  • Sergio de los Santos-Villalobos,
  • Magali Ruiz-Rivas,
  • Ramón Ignacio Arteaga-Garibay and
  • José Martín Ruvalcaba-Gómez

The prickly pear cactus (Opuntia ficus-indica L.) is an emblematic crop for Mexico’s economy, gastronomy, and culture. Microbial communities play an important role in the health, development, and productivity of crops. This study used 16S rRNA...

  • Article
  • Open Access
9 Citations
3,435 Views
19 Pages

Patterns of Coevolutionary Adaptations across Time and Space in Mouse Gammaretroviruses and Three Restrictive Host Factors

  • Guney Boso,
  • Oscar Lam,
  • Devinka Bamunusinghe,
  • Andrew J. Oler,
  • Kurt Wollenberg,
  • Qingping Liu,
  • Esther Shaffer and
  • Christine A. Kozak

18 September 2021

The classical laboratory mouse strains are genetic mosaics of three Mus musculus subspecies that occupy distinct regions of Eurasia. These strains and subspecies carry infectious and endogenous mouse leukemia viruses (MLVs) that can be pathogenic and...

  • Article
  • Open Access
3 Citations
3,306 Views
14 Pages

The Genetic Architecture of a Congenital Heart Defect Is Related to Its Fitness Cost

  • Ehiole Akhirome,
  • Suk D. Regmi,
  • Rachel A. Magnan,
  • Nelson Ugwu,
  • Yidan Qin,
  • Claire E. Schulkey,
  • James M. Cheverud and
  • Patrick Y. Jay

31 August 2021

In newborns, severe congenital heart defects are rarer than mild ones. This epidemiological relationship between heart defect severity and incidence lacks explanation. Here, an analysis of ~10,000 Nkx2-5+/− mice from two inbred strain crosses illustr...

  • Article
  • Open Access
5 Citations
5,898 Views
23 Pages

6 November 2024

In the post-COVID-19 era, the need for a resilient workforce to maintain a competitive advantage has become increasingly critical. Despite advancements, there is a research gap in understanding how employee resilience is influenced by high-involvemen...

  • Review
  • Open Access
949 Views
12 Pages

18 November 2025

The interaction between human salivary alpha-amylase (HSAmy) and amylase-binding oral streptococci (ABS) helps determine the bacteria that colonize the oral cavity by establishing dental biofilms. Streptococci are important pioneer species of the ora...

  • Review
  • Open Access
881 Views
45 Pages

15 January 2026

The emerging paradigm of “fusion of lifeforms” represents a transformative shift from conventional human–machine interfaces toward deeply integrated symbiotic systems, where biological and artificial components co-adapt structurally...

  • Article
  • Open Access
5 Citations
2,420 Views
14 Pages

Dissecting the Roles of Phosphorus Use Efficiency, Organic Acid Anions, and Aluminum-Responsive Genes under Aluminum Toxicity and Phosphorus Deficiency in Ryegrass Plants

  • Leyla Parra-Almuna,
  • Sofía Pontigo,
  • Antonieta Ruiz,
  • Felipe González,
  • Nuria Ferrol,
  • María de la Luz Mora and
  • Paula Cartes

23 March 2024

Aluminum (Al) toxicity and phosphorus (P) deficiency are widely recognized as major constraints to agricultural productivity in acidic soils. Under this scenario, the development of ryegrass plants with enhanced P use efficiency and Al resistance is...

  • Feature Paper
  • Article
  • Open Access
27 Citations
9,264 Views
21 Pages

1 July 2019

In this article, the statistical process monitoring problem of the Tennessee Eastman process is considered using deep learning techniques. This work is motivated by three limitations of the existing works for such problem. First, although deep learni...

  • Review
  • Open Access
13 Citations
9,055 Views
17 Pages

22 September 2016

Anaplasma phagocytophilum and Borrelia burgdorferi are two tick-borne bacteria that cause disease in people and animals. For each of these bacteria, there is a complex of closely related genospecies and/or strains that are genetically distinct and ha...

  • Article
  • Open Access
889 Views
17 Pages

The Role of MHC-II Diversity over Enclosure Design in Gut Microbiota Structuring of Captive Bengal Slow Lorises

  • Rong Jiang,
  • Xiaojia Zhang,
  • Lei Xie,
  • Yan Zhang,
  • Changjun Zeng,
  • Yongfang Yao,
  • Huailiang Xu,
  • Caoyang Yang,
  • Xiao Wang and
  • Chuanren Li
  • + 2 authors

21 August 2025

The endangered Bengal slow loris (Nycticebus bengalensis) relies heavily on captive/rescue populations for conservation. This study investigated the critical link between Major Histocompatibility Complex (MHC) class II DRB1 exon 2 (DRB1e2) genetic va...

  • Article
  • Open Access
6 Citations
2,650 Views
11 Pages

The Influence of Temperature and Host Gender on Bacterial Communities in the Asian Citrus Psyllid

  • Rui-Xu Jiang,
  • Feng Shang,
  • Hong-Bo Jiang,
  • Wei Dou,
  • Tomislav Cernava and
  • Jin-Jun Wang

25 November 2021

The Asian citrus psyllid, D. citri Kuwayama is the primary vector for Candidatus Liberibacter asiaticus (CLas), which causes a destructive disease in citrus plants. Bacterial symbionts are important determinants of insect physiology, and they can be...

  • Article
  • Open Access
735 Views
33 Pages

A Replication-Competent Flavivirus Genome with a Stable GFP Insertion at the NS1-NS2A Junction

  • Pavel Tarlykov,
  • Bakytkali Ingirbay,
  • Dana Auganova,
  • Tolganay Kulatay,
  • Viktoriya Keyer,
  • Sabina Atavliyeva,
  • Maral Zhumabekova,
  • Arman Abeev and
  • Alexandr V. Shustov

24 January 2026

The flavivirus NS1 protein is a component of the viral replication complex and plays diverse, yet poorly understood, roles in the viral life cycle. To enable real-time visualization of the developing replication organelle and biochemical analysis of...

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