Search Results (91)

Background/Objectives: The rapid emergence of antibiotic-resistant Escherichia coli in food and clinical environments necessitates new, clean-label antimicrobials. This study assessed eight Greek native essential oils—oregano, thyme, dittany, rosemary, peppermint, lavender, cistus and helichrysum—for activity against six genetically and phenotypically diverse E. coli strains (reference, pNorm, mecA, mcr-1, blaOXA and O157:H7). We aimed to identify oils with broad-spectrum efficacy and clarify the chemical constituents responsible. Methods: Disk-diffusion assays measured inhibition zones at dilutions from 50% to 1.56% (v/v). MIC and MBC values were determined by broth microdilution. GC–MS profiling identified dominant components, and Spearman rank-order correlations (ρ) linked composition to activity. Shapiro–Wilk tests (W = 0.706–0.913, p ≤ 0.002) indicated non-normal data, so strain comparisons used Kruskal–Wallis one-way ANOVA with Dunn’s post hoc and Bonferroni correction. Results: Oregano, thyme and dittany oils—rich in carvacrol and thymol—exhibited the strongest activity, with MIC/MBC ≤ 0.0625% (v/v) against all strains and inhibition zones > 25 mm at 50%. No strain-specific differences were detected (H = 0.30–3.85; p = 0.998–0.571; p_adj = 1.000). Spearman correlations confirmed that carvacrol and thymol content strongly predicted efficacy (ρ = 0.527–0.881, p < 0.001). Oils dominated by non-phenolic terpenes (rosemary, peppermint, lavender, cistus, helichrysum) showed minimal or no activity. Conclusions: Phenolic-rich EOs maintain potent, strain-independent antimicrobial effects—including against multidrug-resistant and O157:H7 strains—via a multi-target mode that overcomes classical resistance. Their low-dose efficacy and GRAS status support their use as clean-label food preservatives or adjuncts to antibiotics or bacteriophages to combat antimicrobial resistance. Full article

The Western genre has traditionally been associated with American identity and male-dominated narratives. However, recent decades have seen increasing attention to female protagonists, particularly the European woman as a cultural mediator within the frontier context. This study aims to identify the archetypes of the European woman in the Western genre through a diachronic and comparative analysis of the visual language found in European painting from the late 17th to early 19th centuries and in 20th–21st century cinema. The research methodology combines narrative, visual, and semiotic analysis, with a focus on intermedial and intertextual parallels between visual art and film. The study identifies nine archetypal models corresponding to goddesses of the Greek pantheon and traces their transformation across different aesthetic systems. These archetypes, rooted in artistic traditions such as Baroque, Classicism, Romanticism, and others, reappear in Western films through compositional, symbolic, and iconographic strategies, demonstrating their persistence and ability to transcend temporal, medial, and geographical boundaries. The findings suggest that the woman in the Western genre is not merely a central character, but a visual sign that activates cultural memory and engages with deep archetypal structures embedded in the collective unconscious. Full article

The comprehensive analysis of microbial communities reveals the unique microbial identity of different olive varieties, paving the way for new strategies in their development and commercial exploitation. In this context, the present study aimed to explore the microbial diversity and functional characteristics of Tsounati variety olives from the Monemvasia region of Peloponnese, Greece, that were naturally fermented for three months. The bacterial and fungal microbiota of both olives and brines were fingerprinted throughout the fermentation through classical microbiological analysis combined with molecular techniques. Among the 148 isolated bacteria, 85 were lactic acid bacteria (LAB), and 63 belonged to the Enterobacteriaceae family, while the 178 fungal isolates comprised 136 yeasts and 42 non-yeast or yeast-like fungi. Metataxonomic analysis confirmed the dominance of the bacterial genera Lactiplantibacillus, Leuconostoc, along with the Enterobacteriaceae family, and it revealed the presence of Coleofasciculaceae cyanobacteria mostly in olives. The dominant fungal genera were yeasts, namely Saccharomyces, Nakazawaea, and Cyberlindnera. Using the Folin–Ciocalteu assay, the average total polyphenol content of Tsounati fermented olive samples was 761.80 ± 128.87 mg gallic acid equivalents kg⁻¹ after 90 days of fermentation. The concentrations of the triterpenic, maslinic, and oleanolic acids, as determined by HPLC, remained stable throughout fermentation, with average values of 4764 and 1807 mg kg⁻¹, respectively. Finally, sensory analysis revealed the rich aromatic character of Tsounati variety, highlighting its potential to be used for Greek-style table olive production. Full article

Friedrich Nietzsche can be an awkward topic for classicists and ancient philosophers, especially since an important part of his heavily critical philosophy begins as a reaction to, and critique of, his contemporary classical scholarship with which he was intimately familiar, being one of the most impressive ‘products’ of its development. Nietzsche was a thinker who in many ways turned the prevalent opinions about Greeks and contemporaries upside down, challenging his predecessors and successors with provocative readings of some of the most cherished philosophies in Western culture. This essay examines Nietzsche’s treatment of sophists—an important group of intellectuals whose reception had suffered greatly under the devastating judgement of Plato and Aristotle. While recent scholarship frequently regards sophists as philosophers, Nietzsche’s contemporaries were generally extremely dismissive of this group and regarded them in negative light as illegitimate thinkers and opponents to their contemporary ‘true’ philosophers (i.e., Socrates, Plato, and Aristotle). This paper traces two different moments in Nietzsche’s philosophical output that exhibit closer engagement with the sophists: the ‘early’ Nietzsche regards sophists as innovators in language and style, the ‘late’ Nietzsche sees them as countercultural revolutionaries. Despite the fact that in both stages, sophists are introduced as champions for ideas that are central to Nietzsche’s own philosophical preoccupations (the development of language, the overthrowing of values), his treatment of this group of intellectuals appears at first sight superficial and surprisingly unenthusiastic. The paper will examine our existing sources on Nietzsche’s treatment of the sophists and will suggest, ultimately, that his engagement with them was probably far more complex and multilayered than has been thus far assumed. Full article

Background: Patients with bipolar disorder (BD) face many challenges as many basic cognitive and non-cognitive domains can be affected by their disease. Financial capacity requires complex cognitive functioning and is little investigated in BD, especially in the Greek cultural context. Objectives: This study, for the first time, is focusing on whether financial capacity shows deficits in female euthymic BD patients compared to controls and what the self-estimations of the patients for their performance are. Materials and Methods: Patients and a sample of one-to-one matched healthy controls were examined with a detailed neuropsychological battery and the Legal Capacity for Property Law Transactions Assessment Scale (LCPLTAS). Before their neuropsychological assessment, participants responded to a single-item five-point Likert scale about their financial capacity. Results: Findings extend earlier work in other groups of older patients and indicate that euthymic BD patients’ performance is lower than that of the control group in various subdomains and total score of LCPLTAS (p < 0.001), resembling the performance of patients with a diagnosis of Mild Cognitive Impairment (MCI). However, euthymic BD patients are not aware of their cognitive deficits compared to healthy controls and overestimate their financial capacities as they have more positive estimations regarding their financial capacity than controls (χ²(1) = 8.315, p = 0.004) despite their lower real performance. In addition, from a number of classic neuropsychological tests administered, only Trail Making Part B correlates with LCPLTAS scores for the group of euthymic BD patients (rho = −0.561, p = 0.005). Conclusions: The results support that special care must be provided for euthymic BD individuals, so we can prevent financial exploitation. Full article

The pharmacology of antimicrobial agents comprises pharmacodynamics and pharmacokinetics. Pharmacodynamics refers to studying drugs’ mode of action on their molecular targets at various concentrations and the resulting effect(s). Pharmacokinetics refers to studying the way(s) in which drugs enter the body and are distributed to their targets in various compartments (such as tissues) and how local drug concentrations are modified in time, such as by metabolism or excretion. Pharmacodynamics and pharmacokinetics constitute pivotal knowledge for establishing the breakpoints used to identify the appropriate antimicrobial agents for infection therapy. Antibiotic resistance is the biological force opposing antimicrobials’ pharmacological effects. However, we do not have a term similar to pharmacology for microbial antibiotic resistance reactions. Here, we propose the new scientific field of antechology (from the classic Greek antechó, resistance), studying the dynamics and kinetics of antibiotic resistance molecules which oppose the effect of antimicrobial drugs. Antechodynamics refers to the study of the molecular mechanisms through which antibiotic molecules are chemically modified or degraded by particular bacterial resistance enzymes (primary effectors) or drive the modification of an antibiotic’s target inhibition sites through molecules released by antibiotic action on the microorganism (secondary effectors). Antechokinetics refers to the study of the processes leading to bacterial spatial cellular (subcellular, pericellular, extracellular) localizations of the molecules involved in antibiotic detoxifying mechanisms. Molecules’ local concentrations change over time due to their production, their degradation, and ultimately their excretion rates. We will examine the antechodynamics and antechokinetics for various antimicrobial classes and the relation between pharmacodynamics/pharmacokinetics and antechodynamics/antechokinetics. Full article

This study presents an innovative approach to differentiate Southern Greek yellow prickly pear samples according to geographical origin based on physicochemical parameters, mineral composition, and bioactive compounds using advanced chemometrics. A total of 56 yellow prickly pear samples were collected from four distinct Greek regions (Crete, Paros, Symi, Peloponnese) during the 2019 and 2020 harvest seasons. A multi-platform analytical strategy was employed, combining classical physicochemical analyses and UV spectrophotometry for total antioxidant activity with cutting-edge techniques such as UPLC-MS/MS for precise quantification of vitamins and antioxidants, and ICP-MS for mineral profiling. In total, thirteen physicochemical parameters, nineteen macro-, micro-, and trace elements, nine vitamins, and seven antioxidants were identified and quantified. Application of MANOVA and Linear discriminant analysis (LDA) revealed that eight physicochemical parameters, ten mineral elements, and sixteen bioactive compounds played a crucial role in sample geographical differentiation. The classification success rates using the cross-validation method were 82.1% for physicochemical parameters, 75.0% for minerals, and an impressive 96.4% for vitamins and antioxidants highlighting the robust tool for the geographical differentiation of Southern Greek yellow prickly pears. Full article

This research is driven by the expansion and popularity of the Manosphere network in the last decade, causing online and offline harassment of women. The study examines the phenomenon of the Manosphere in the Greek digital space and, more specifically, it researches the case of the popular, anonymous, and public accessed Facebook page of “Όχι, Δεν Είσαι Μισογύνης” (No, you are not a misogynist). The study’s research questions are whether the Greek Manosphere follows the same patterns of the international Manosphere groups and how gendered identities and roles are represented in its discourse. In order to answer the research questions, the study combines the method of thematic analysis and the approach of critical discourse analysis. The “Όχι, Δεν Είσαι Μισογύνης” (OΔΕΜ) page is found to be a case of the Men’s Rights Activists subculture of the Manosphere, with the main topic of interest being the online activism against feminism. Although the Facebook page reproduces traditional gender stereotypes and representations, a crucial difference from “classic” patriarchal perceptions is that the OΔΕΜ discourse portrays women as privileged, socially dominant and violent, while men are depicted as victims, discriminated by women and the social system. This inversion of reality is executed by the misinterpretation and falsification of data, along with the appropriation of activist and feminist discourse, which could lead to latent, or overt, misogynist perception and stereotypes (re)gaining popularity. Full article

Background/Objectives: This article explores the use of Ancient Greek as a prompt language in DALL·E 3, an Artificial Intelligence software for image generation. The research investigates three dimensions of Artificial Intelligence’s ability: (a) the sense and visualization of the concept of distance, (b) the mixing of representational as well as mythic contents, and (c) the visualization of emotions. More specifically, the research not only investigates AI’s potentialities in processing and representing Ancient Greek texts but also attempts to assess its interpretative boundaries. The key question is whether AI can faithfully represent the underlying conceptual and narrative structures of ancient literature or whether its representations are superficial and constrained by algorithmic procedures. Methods: This is a mixed-methods experimental research design examining whether a specified Artificial Intelligence software can sense, understand, and graphically represent linguistic and conceptual structures in the Ancient Greek language. Results: The study highlights Artificial Intelligence’s possibility in classical language education as well as digital humanities regarding linguistic complexity versus AI’s power in interpretation. More specifically, the research not only investigates AI’s potentialities in processing and representing Ancient Greek texts but also attempts to assess its interpretative boundaries. The key question is whether AI can faithfully represent the underlying conceptual and narrative structures of ancient literature or whether its representations are superficial and constrained by algorithmic procedures. The study highlights Artificial Intelligence’s possibility in classical language education as well as digital humanities regarding linguistic complexity versus AI’s power in interpretation. Conclusions: The research is a step toward a more extensive discussion on Artificial Intelligence in historical linguistics, digital pedagogy, as well as aesthetic representation by Artificial Intelligence environments. Full article

In classical biological control of weeds, the risk posed by a candidate agent to close relatives of the target weed in the intended area of release is a key criterion (i.e., candidate agents that demonstrate a high degree of host specificity). In this study, we investigated if the rosette crown-feeding fly Botanophila turcica Hennig (Diptera: Anthomyiidae) could meet this criterion and thus be considered a good candidate to control saffron thistle Carthamus lanatus L. (Asteraceae: Cardueae) in Australia. Previous studies indicated that B. turcica is specific to Ca. lanatus and did not infest the closely related crop, safflower (Carthamus tinctorius L.). However, more recent field observations made in Greece reported that B. turcica infested safflower in cultivated fields. To determine if B. turcica is safe for release as a biocontrol agent, we re-examined the host range of B. turcica by performing new host-specificity testing combined with field surveys carried out in the south of France during two consecutive years. We also investigated the species identity of the flies by comparing DNA sequences (COI barcode region) of specimens collected in France from Ca. lanatus and Centaurea solstitialis L. with those from Greece collected from Ce. solstitialis and Centaurea diffusa Lam. Our COI analyses confirmed that French and Greek samples identified as B. turcica belonged to the same species, while a second group of Greek samples matched B. brunneilinea, indicating two distinct species. Our results also demonstrated that B. turcica has a wider host range than previously suggested. Laboratory testing indicated that Ca. lanatus, Ca. tinctorius, and Ce. solstitialis are suitable for the development of B. turcica. Field surveys also revealed that Ce. diffusa is part of the host range of the fly. Based on the results reported here, B. turcica may have the potential to control both the target weed, Ca. lanatus, and Ce. Solstitialis, but it may also be a threat to safflower, Ca. tinctorius. Further investigations to assess under what conditions B. turcica attacks Ca. tinctorius may help clarify the level of risk to Australian growers. Full article

This study explores the relationship between formant frequencies and the directivity patterns of the Greek singing voice. Recordings were conducted in a controlled acoustic environment with four professional singers, two trained in classical music and two in Byzantine chant. Using microphones placed symmetrically on a hemispherical structure, participants sang the Greek vowels across different registers. Directivity patterns were analyzed in third-octave bands centered on each singer’s first three formant frequencies (F1, F2, F3). The results indicate that directivity patterns vary with register and center frequency, with differences observed across vowels and singers. These findings contribute to vocal production research and the development of simulation, auralization, and virtual reality applications for speech and music. Full article

Accurate drought identification is important for both scientists and decision-makers to be able to make informative decisions. In this study, parametric and non-parametric approaches for analyzing meteorological drought are compared, aiming at simplifying the calculation of the Standardized Precipitation Index (SPI). The comparison is performed across various meteorological stations covering the entire territory of Greece, using monthly rainfall data spanning from 1961 to 2021. Meteorological drought is assessed through the SPI for the 12-month reference period. A two-parameter gamma distribution, with parameters estimated using the maximum likelihood estimation method, is employed for the estimation of the SPI drought index as the parametric classic approach. For the non-parametric approach, the SPI drought index is estimated using six empirical probability plotting positions: Beard, Blom, Cunnane, Gringorten, Hazen, and Weibull. Results indicate that the empirical approach can effectively identify drought events in comparison to the classic approach. However, caution is advised, particularly when different drought classes are identified, as the non-parametric approaches may underestimate drought severity. In addition, for the Greek meteorological conditions, the results revealed that in the case of extreme drought events, the estimation of SPI employing the classic approach is to be preferred. Full article

This review examines how ancient Greek and Roman literature can inform sustainable cultural tourism, offering valuable insights for managing cultural heritage and landscapes responsibly. By analyzing works such as Homer’s Odyssey, Virgil’s Georgics, and Pausanias’ Description of Greece, this study bridges classical wisdom with modern challenges such as climate change, over-tourism, and shifts in accessibility. Key findings and practical solutions include respect for sacred landscapes: for example, ancient reverence for sites such as Delphi demonstrates how cultural heritage can be protected by fostering ethical relationships with significant places. Tourism policies can draw on this perspective to integrate conservation efforts with the promotion of historical sites. Moreover, sustainable resource stewardship is highlighted: for example, Roman agricultural ethics, as seen in Virgil’s Georgics, emphasize harmony between human activity and nature. These principles can inform strategies for managing tourism’s environmental footprint, such as prioritizing local resource sustainability and preserving natural ecosystems. Models for slow tourism are also provided: for example, epic journeys such as Homer’s Odyssey highlight the value of slow, immersive travel. By promoting meaningful engagement with destinations, tourism can reduce environmental stress while enriching visitor experiences. In addition to these findings, the study underscores the communal responsibility inherent in ancient principles, advocating for tourism models that balance individual benefits with collective well-being. Practical applications include promoting community-based tourism models, fostering partnerships with local stakeholders, and incorporating ethical guidelines into tourism management to mitigate negative impacts on cultural sites and ecosystems. In conclusion, this review argues that revisiting classical texts through the lens of the environmental humanities offers actionable strategies for sustainable tourism. By adopting ancient values of stewardship, reverence for nature, and civic responsibility, stakeholders can create tourism models that preserve cultural and environmental heritage while ensuring long-term economic and social benefits. Full article

As a contribution to the reflection on whether classic Greek philosophy gave priority either to Necessity and the Fatum or to freedom, this paper endeavors to prove three theses: (1) according to Aristotle, God caused the being of the world by an act of His will; (2) such an act of divine will was free and not necessary; (3) however, such causation is subject to the necessity of supposition. In order to do this, the paper delves into the interpretation of many passages contained in the Physics, the Metaphysics, De anima, Nicomachean Ethics, Eudemian Ethics as well as Politics, Topika, De generatione et corruptione, De coelo and De partibus animalium. This interpretation benefits from Aquinas’ acute analysis. In such passages, Aristotle holds that (1) God’s causal power must be exercised not in proportion to the magnitude of divine power, but to the requirements of the effect; (2) such a way of acting is similar to human power; (3) nature is subject to teleology because it is caused by an intellectual power; (4) God is the highest intelligible and the highest good, totally autarchic; and (5) just as the highest intelligible is simultaneously also intellect, so too is the highest good simultaneously also will. Full article

This essay will draw from the classical Greek notions of cosmopolis and cosmopolitanism—world citizenship—as a heuristic for contemplating the question of contemporary participation in a wholly good global society. The first part of this paper will explore how the ancient notion of cosmopolis offers contemporary thinkers a compelling hermeneutic for considering cultural growth over history. Then, in part two, it will focus on spirituality, returning to the ancient Greek world through the lens of Pierre Hadot’s work on philosophy as spiritual exercise. Finally, this essay will engage Bernard Lonergan’s suggestion that cosmopolis as a heuristic is fundamentally oriented toward reversing the kinds of decline that emerge from shortsightedness and various forms of bias. Full article